Basic Information

Insect: Locusta migratoria
Gene Symbol: Fasn
Assembly: GCA_026315105.1
Location: scaffold241539:8256-77064[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 1.3e-05 0.0014 19.2 0.8 2 23 717 738 717 738 0.97

2 8 0.0039 0.41 11.4 0.1 1 21 741 761 741 762 0.95

3 8 0.00092 0.098 13.4 4.3 1 23 779 801 779 801 0.98

4 8 1.1e-05 0.0011 19.5 0.5 1 23 813 835 813 835 0.99

5 8 0.0078 0.83 10.5 0.9 2 23 861 882 860 882 0.95

6 8 0.099 11 7.0 7.3 1 23 960 982 960 983 0.95

7 8 0.0015 0.16 12.7 0.7 1 23 1014 1036 1014 1036 0.96

8 8 1.4e-05 0.0015 19.1 2.7 1 20 1040 1059 1040 1061 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	1.3e-05	0.0014	19.2	0.8	2	23	717	738	717	738	0.97
2	8	0.0039	0.41	11.4	0.1	1	21	741	761	741	762	0.95
3	8	0.00092	0.098	13.4	4.3	1	23	779	801	779	801	0.98
4	8	1.1e-05	0.0011	19.5	0.5	1	23	813	835	813	835	0.99
5	8	0.0078	0.83	10.5	0.9	2	23	861	882	860	882	0.95
6	8	0.099	11	7.0	7.3	1	23	960	982	960	983	0.95
7	8	0.0015	0.16	12.7	0.7	1	23	1014	1036	1014	1036	0.96
8	8	1.4e-05	0.0015	19.1	2.7	1	20	1040	1059	1040	1061	0.94

Sequence Information

Coding Sequence: ATGGGAGGCGTGTGCAGAGCTCGTAATTGCTTTCGTTCTAAAGATAAGTGTCCTGATCTACCGTTCTTCACTTTTCCTAAAAACCCTGTCAGTGCCAAGAAATGGATTACAAACATTGGTGACCCAGAACTGCTGAAGCGGCCACCTAGCGCCCTGAAGAACAATGTTGTTTGTGCTCTTCATTTCGAAGAAAAGTGTTTTGTGAACAAGAAGAAACGCTCGCTCGTGAGAAACGCTGTCCCTACAATATTCAACATTCCTCCTCTCAGAACTGAAGAAAGTCATAAAAATGACATTCATTCGAAATCGGAAAGAAGAGACGTTCCGGGGTGTAATAGTGGAGCACTTTTCTCTTGCAATGTTGAAACATTTGATAACTGGCATCATCAGATTGACGCTGTTACAGAGCAGCTACTGTGCTTACTACCCGAAAATAGCAGACATACTCCGCAGCTACAGCCACAAACAGAAAAAAAGTGTGTTGACGCATATACGCAGTATGAGAACGAAACTGAAAGTCGTGAATTTGAAAAAAGATTAAACGATCTGAATAAAACTACCAACGTTGAATCTAGTGATACAGTTCCAAGAGTGCAATTACTGTGTCGTTTGTGTTCAAAGCTTACTCACCGTGAAAGTGTGATACCAATTTTTAGTTATGAAGCGGAAAAAATCCACCTAGAAGCAATGATTAATTCTATTATGCCAACAAAAGTTATACAGGACGATGGTTTGCCACAACAAGTTTGTAACTTGTGTGTACGAAAACTGACATTTTGTTACGATGTAAGAAAAGAATTTTTAGCTTCAGACAAAAGATTACGCGATCTTTTGGGCATTGTAGCTGTGAAGGACTCTGCTGAAATTCCCTCTACTAAAGGAAACGTCGAGGAACAATCAACTGCACAGGGAAGCCCGTCTGCTGAAGCCATCACATCTCCAACAGAAAATGTAACAAAAGTACAACTGAAAGAAAATGAGCCACCCTCAAGAGTACTGCATACTGAGGAAACAACAACAGCACAGTCTGAAACCATGAAAAGGGGTTCTAAGAAAAGAAAGAGAGTTGTGGCTGCAGTGAAAAATAAGAATACTAGGAAAAAGGATGATAAAATCCCAAAAGTAACAAAATCACGTTCTCATGGGAGAAGAACCACAATTGAAGATACACCAAAATTAATAGAGTCTACTCCTCAAGGGAAAAGTACCATAACTGTTGATGTACCAAAATTAATCAAGTTACCTCATAGCAAAAAAGCCACAGATGAAGAAAGCCCAAAATTAATAAAGTCTGCACCTCACATCAAAAAAGCTGCAGCTGAAGAAAGCCCAAAATTAATAAAGTCGGCTCCTCATGGGAAAAAGTCCACAGGAGAAGAGATCACAAAGCTAGTAAAAACTGGCTCTCATGGTAAAAAGACTACAACTGAAGAAAACTCAAAATTAGTGAAGGCTGGTCCTCATGGAAAAAATAATACAGTTGAAGAAATTCCAGAATTAGTTCATGCTGATCCTAATGAAGAAATTCTCACAGTTGAAGAAATACCAAATGTAGCAAAGCCTGGTCCTCAAGATACAAAGACCACAGCTGAAGATAGTGATTTTGAAAATGATAGCAATTATGAAATTCACTGGTATGATGAGGCATATGATGATAGTATTTCAGAAGATATGGGCACCAGTGACAATATCCAGAATAACAAAAAATTATTAATGAACAACGCAAAAAAACAAATTGCAAGTGAGGCTACAAAGATGGATATAGAGCCTATTGCAGACGAAGAAATGAAAAGTGTTAAGGATTGTAACATGACATTAAACCACAAAATGTTGAACGAAAGTAAAGCAGATGATAGTATTGTGAATGATATTCACATGAATGAATGTAAAGTGGATGAGAGCATAATTAATGACAGTAATGTAAATGAGAGCAAATTGGATACTGGTATCTCTGTTCCAATTACAAACAGCCGTCCCTCTCCCAAAGAAGGCTCTCTTAGCAGTGTCTCTCTGAGACAAAAAATTGGATCCGGTAGTGTTAAAGTGCGGCTAATGACAGAGAGGCAAAAACTATTAAAGCTGAAAATGAAAACCCAAAATAAACTCTTAAAACAAGGTAACAAAAAGAAAGTGTTACCCGCAAAAAATTCATGTTCAGAATGTAATAAAAGCTTCGCATCTAAACTGAAGCTGGAGCGACACATACTTATGCATAGTAAATATGAGTGTGCTGTGTGCAGCACCATATTTAATACTTCTGAAGAACTGTCAAATCACAGTAGAGAGAATTGCCTTGCAAAATTGAAGGCTGTCACAGATGCAGCAGCCGCAGCTCATGAATGTGAAATTTGTAGGCGCACATTTAAGACTCGCCAACGATTATTACTTCATACAAAAACGCATTCAACATTCCTAGGTCATTCAGCGACTGTACCTTATACGTGCAAGGTTTGCCCAAAAGCATTCCCAACAAGGATTAGACTGAAACAGCATCTGAAAATTCATAAACCAGAAAAGCCTAAAAATAATCAATCATTATTTCGACGTCGTGTTCAACAGACTGTAAGCACCCCAACTCTAAAATGTGAGACTTGCAGTAAATTTTTCAACAGTGTGATAGAATTTGAAAAACATAGAGAAGAGCATGCTTCCAGTAGCTCCACTATTCACGTGAATGGTGCACATACAGCTGAAATAACTTCAGATACACATAATATAGATAAACCAGGAAGCGGCTCAGGTGGCTCTGTTGATGTGAGTTCTGTGGCCGCAGATGTTCAGGATCCAGAACAGACCAAAACTGTTAAAGAAGATGGTATTATGAAAGTTAAAGTACCTCATTTGGAAAAAAATCTAATAATCACATCTGCTGATCAGTTTGTTTGTGACATATGTGACTGTAAGTTTTCCTCAAAGCACTTCCAAGAGGAACATAAGAAAGTGCACCATTCAACGCCTGAACAAAGCAGTGTTCCTGTGGCTACATCTCCAGTGGAATCAACTGTAGAGCTACTTCAGACGCCAGAACGAGGCAAATTGTACTTTTGTGACCAGTGTGGGGAAGGCTATGAGCGTAAGAGATCTTTAGCATTACACAGGTTTTCACACACATCCAGTCATCGTTGTCCACATTGCCACCAGTCATTTTCTTCAGAGGATTCATTGACACGTCATCTTGAAAACTGTTTAGACGTGAAAGAAGAAGCTGCTGAGGGGAATAATCAGCTATAA
Protein Sequence: MPARFPEVEVHAPVGVRTGDAPTVNSVPNGHWNMDDDIVITGISGRLPESANIEEFKQQLFEGVDLVTDDERRWPSGLHGLPTRTGKLKDLAHFDATFFGVHAKQAHVMDPQLRMLLELTHEAIVDAGVNPVDVRGSRTGVFIGVSDSESDEYWTADPEKVNGYGLTGCCRAMFPNRISYTFDFSGPSYAIDTACSSSMFALQQAMNAMRTGQCDAAIVGGVNLLLKPTCSLQFHRLSMLSPQGMCKAFDSSGNGYVRSEAAVVIYLQKSSVAKRVYATVVNAKTNTDGYKTQGITFPSGEMQKKLVKEVYAEVGLNPSDVAYVEAHGTGTKVGDPQEVNAIADVFCKDRNSPLLIGSVKSNMGHSEPASGLCSIAKVVIAMEAGFLPANLHFKEPNPDIPALLDGRLQVVDKTIPWNGGLAAVNSFGFGGANAHVVLRSNPKPKTPAIQDGIPRLITVSGRTDEAVSAFLEKIENTPRDDDFISLVHEIHSTNITGHNYRGYTVLGSSSPVREVSQFDGEKRPVWFVFSGMGTQWAGMGSDLLQIEVFEKAIRKCSEALQPEGVNLYEIIVNGTETTFDNVLNSFISVAAIQVALVDVLSSLGIHPDGIVGHSVGELGCAYADGTFTAEQTVLAAYWRGRSILESKLPRGSMAAVGLTWEDAKARCPPELVPACHNSADSVTVSGPPDAIDKFVKTLQAEGIFAKEVNSSGVAFHSRYIADAGPKLRKCLEKIIPNPKQRTSRWISSSIPESAWGTSLAQWSSAAYHVNNLLSPVLFSEALKFVPENAIVVEVAPHCLLQAILKRSLAPTCTNVGLMKRGHKDNKEFFFSNIGKLYNVGLQPKLAQFYNKISYPVARGTPMIAPLIQWDHSSEWSVASFSGKGGSRSGECIIEVDLSKEQDNFLSGHAIDGRVLFPATGYLTLVWKTFAKLQGTSFEDLAVVFEDVQFHRATIMPKEGSVKFLVNIFDGSGTFELCEGGAVVVSGRIYVPEDPDHEMLNLPAPAKLSENKELLPLTTSDVYKELRLRGYDYGGIFRGIVESDNRGVNGKLNWVNNWISFMDTMLQFSILGQNTRELYLPTRLQRAVINPKKHKQIVETISEDDGVPVHMYRNINILKSGGIELRGLKASLAPRRQQSQAAPKLEQYTFVPYANVCKKEVTIEEGPRVRQQALTVCLQIALENSGGALKMKVAEVADDRQPETLLAPQIIDILESEPILTVDLTVASASPEMFASTVESLGVKMVNKNISSEPVDQNCHIVVGTGILQRPAGVLDNMVVSLKEGGFILLEEGRSVVENHKIPDGLELVARQDAGLHSFVLLRKAIAPDYAVQIQVTEKNFDWVEPLKSALKQSETEGTKILVVCCGENHCGIIGMINCIKQEPGGNNVRCIFVQDEKAPAFSRNHEFYAAQLKKDLVLNVLKNGIWGSYRHMHLNSVLKDSATALQVEHAYINALTRGDLASLRWIEGPLTYYRPERFPEKELCHVYYAPLNFRDVMLATGKLPPDALPGDLAGQDCILGLEFSGRNSAGKRVMGMVAARGLATTVLADPGFLWEVPDKWTLEEAATVPVVYATSYYALVVRGQMRPGDSVLIHAGTGGVGQAAIAIALHMGCTVFTTVGSAEKRAFLKQRFPQLTDRNIANSRDTSFEQHVLKETDGRGVDLVLNSLAEEKLQASVRCLAKDGRFLEIGKYDLSNNNPLGMAMFLKNTTFHGILLDALFESNSVAKKEVFRLVTEGIKSGAVRPLPATVYTENQVEQAFRFIGSGKHIGKVVLKIRNEEQEKQVKPTTKLVPAIPRTYMNPEKVYILAGGLGGFGLELTNWLISRGATNIVLTSRSGIRTGYQSLCIRRWREAGIVVHVSTADFSKEKGAEQLIKEATKLGPVGGIFNLAAVLRDAFMENQSAENFEAVCMPKVTGTKNLDKVSRLLCPELDYFVVFSSVSCGRGNAGQANYGLANSAMERLCESRQAAGLPGLAIQWGAIGDVGLILETMGDNDTVVGGTLPQRMSSCLATMDTFLQQPYPVLASMVLAEKKGRSADAGSTVALLDAVANILGIKDVSTVSAQASLADLGMDSLMGAEIKQTLERNYDLVLSAQDIRNLTFQRLSELSNSGVQGSVSDANGAAPADSTQVQFENLEELMPKDVMVQMPSKGTNKKNAIFIVHPIEGVVTALRELAAELSQPVWGLQCTSEAPLDSIQELAKFYLQHVKKVQPKGPYTVCGYSFGACVAFEMALQLENAGEAVSLFLLDGSPSYVAAHTGNYRARKSLDQKGEECDALTYFVQLFADVDFQKTRQELMALPTWDARLKRSTEFLAGNVRFPVEQLAKAAESFYHKLMAADKYQPSDQYAGSVTLVRAKDIYVSLGDDYGLSKVCKKPVKIHSLKGNHREILFGDSAKKVAEILCSSVLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00912920;
90% Identity: iTF_00912920;
80% Identity: iTF_00912920;