Basic Information

Insect: Locusta migratoria
Gene Symbol: pol
Assembly: GCA_026315105.1
Location: scaffold41225:322231-482636[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00016 0.017 15.8 0.4 1 23 27 50 27 50 0.97

2 12 7.3e-06 0.00078 20.0 2.0 1 23 226 249 226 249 0.98

3 12 0.54 57 4.7 2.3 1 23 421 444 421 444 0.89

4 12 0.034 3.6 8.5 0.2 1 23 495 518 495 518 0.92

5 12 0.00035 0.037 14.7 2.4 1 23 1008 1030 1008 1030 0.98

6 12 0.22 24 5.9 0.8 1 20 1039 1058 1039 1060 0.85

7 12 0.72 76 4.3 2.3 1 17 1122 1138 1122 1139 0.90

8 12 0.00032 0.034 14.9 0.3 1 23 1152 1174 1152 1174 0.97

9 12 0.39 41 5.1 0.2 2 19 1181 1198 1180 1202 0.84

10 12 1.5e-05 0.0016 19.0 1.0 1 23 1208 1230 1208 1230 0.96

11 12 0.11 12 6.8 0.3 1 12 1236 1247 1236 1252 0.85

12 12 1.1e-05 0.0012 19.5 1.4 2 23 1265 1286 1264 1286 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00016	0.017	15.8	0.4	1	23	27	50	27	50	0.97
2	12	7.3e-06	0.00078	20.0	2.0	1	23	226	249	226	249	0.98
3	12	0.54	57	4.7	2.3	1	23	421	444	421	444	0.89
4	12	0.034	3.6	8.5	0.2	1	23	495	518	495	518	0.92
5	12	0.00035	0.037	14.7	2.4	1	23	1008	1030	1008	1030	0.98
6	12	0.22	24	5.9	0.8	1	20	1039	1058	1039	1060	0.85
7	12	0.72	76	4.3	2.3	1	17	1122	1138	1122	1139	0.90
8	12	0.00032	0.034	14.9	0.3	1	23	1152	1174	1152	1174	0.97
9	12	0.39	41	5.1	0.2	2	19	1181	1198	1180	1202	0.84
10	12	1.5e-05	0.0016	19.0	1.0	1	23	1208	1230	1208	1230	0.96
11	12	0.11	12	6.8	0.3	1	12	1236	1247	1236	1252	0.85
12	12	1.1e-05	0.0012	19.5	1.4	2	23	1265	1286	1264	1286	0.96

Sequence Information

Coding Sequence: ATGTCCAAGTGGTCGCGCACCGTGCCGCCGACGCTGCGCCACTCCTCCGACTCCGTGCCGCAGGGCGACTCCTCGCGCTACGTCTGCCTGTACTGTGACAGACGGTTTGATATCCAGAAGAGTCTCCTGTTGCACATGAAGATAGAGCACAAGAACGAGATCATCTCGTCCTCGTCAAAGGAGGCGGAGACCGAGGGCAACTCGGACGACGCGTCAGCGGACGAAGGTGACTGCGGTTGGCAAGAATCGAAAGTCAGTGTTTGGACACTAGAAAGACCTAGTGAAGAAGTGGGAGGTGACGATGATTTCCTCTGCTCGGGGGAGAAAGGAGTGGATAAGGAGTCCCTAAGCGAGTCGGCAACCGGAGCTGCCGCACCGGTCCGTGGCGACGAGGCGCGGGGGCTGAAGACGCACATTTTGACAGCTTTTGGCGGGCTGCTGGAGCGAGCCGTCAGCAGCCGGCTGGAGAAGGGGCTCATCCCTAGAATGGGGCGCCGGCGGGCACCCGTACCATCGCCCGCACCCACGCCCGCGCCGAGAGGCCGGAAGCGCCGCATCTACGCCACGGACCTGGCCAAGCGGGTGCGCCAGCACCTGTCGTCCGGGCAGCCGCGCACGCCGACTCCGCGGCTGCGCTGCGCGGCCGACTCCGTGCCGCAGGGGGACTCCTGGCGCTACACCTGCCTGTACTGCGACCGCCGGTTTGATTTCCGGACGTCTCTCCAGTGGCACATGAAGACGGATCACGAGAACGAGACTGTTGCCTCCACATTGAAGGAGGAGGATTCCGAGGATATTTCAGATGAAGAATTGCCGTGTGAAGATGAATACTGTGAGTCTAAGCCGGCGGTGGAGGAGTATCCGGCCTCGGAGTGGTCCGACATCCGGCCGGACGCGAGAGGTGCGGCAGTGCCGGACGCGGGCAGCAATTCCCCCCCGCGTTACGCGACCGCGCCCACCGCCCCGCCATGCATGCCGCCCCACCCTGACTCCCCAACGGGGAGAGATGCTCCGCCGGGGCGCAGTGCCGACCGGCACTCGGACAGTGTCCCGTCGACCGACCCCACGGCGGCGACAGCACCGTCGGGCCGAGACACCCGGTCGGTGGGGCTGAAGACGCAAATCTCGACGGCACTCGGCGGGCTGCTGGAGCGTGCCGCCGGCACTCGACTGGAGACGGGCGACCCCGCGCACCTCCCTGGCCGCGAGCGTCCGCCACGTGCGTCCGTGAGCGTCTCCGGTGACTGCAGCTCGCACCGCTACGCCTGCTTCTACTGCGACATACGATTCAATAACCTGGGCTCCCACATGTGGCACGTGAAACACGAGCACAAGGACGAGTCTATCTTCTCGGAGTTGAAGCAGACGGAGCCCGGGGACGACGCCTCGACCGGCGGGGACTGCGGCCGTGGTTGGCCCGAACAGAGCCCCGCCAACTGCCCAGTGGAGACGGCCGGTGAAGACACTGTTCGTATCGGCGACTACCTCTGCTCAGAATGTGGTGCCTTGTTCGTCACTTTACACGAACTACTGTTGCACGAGAAAGAGGAGCATACGGCAGCATCGGCAGGGGGTAGACACTCCTCCAGCACGGAGACTGCGTCGGCGAGGGACGGACATTCCTCTAGCACGGAGACCGCGTCTGCGAGGGACGGACATTCCTCTAGCACGGAGACTGTGTCGGCGAGGGATGGACATTCCTCCAGCACGGAAACTGCAGTGTGGCAGGACGACGAGACGGACCTAATGAAATCTCCAGGGCTAGATGCTGATGCCATATTTATTAAGGAAGAAGTGCCAGATGAAATGGGCCCAGTTGTATCTCCACAACCAGAGATCGAGACAATATTTATTAAGGAAGAAACTTCGGCATGGGAGTCACCTGATGACGGCGCTACTGCGCGGGATCCCCTAAGTTTAGAGGAAGAGATTCAGGAAGATCCAGTTGTAGGCTCAGGGTTCAGTGGCTGTATTAAAGAGGAACCAGACGTAGATTTGACCATGGATTCGAGTGACAGCACAATTCAGGAAGATCCAGTTGTAGGCTCAGGGTTCAGTGGCTGTATTAAAGAGGAACCAGACGTAGATTTGACCATGGATTCGAGTGACAGCACAGAGGTTGCCACACGAGGACACACTTCAGATATTACATGCACCGCCGTCCCCGTCTCGACCCGCCCGTCGTTCTCCAAGGTTGGCGGAATCGGACAGACTGCCGCGATCTCGCCCCCCCTCGACAATGGCCGCGAGGAGGACGACACCTCAGCGTTGGGCGCGGTGACGTCGGTGGGCGACCCCGTTACTCCGTTCGGTGTCGCCGACACTGACGGAGGGAACACTACCGCGGGCACACTCGGTGATGACGACAGGAGGCCGCCATACTGTTACGCGGAGCTCATCGCCATGGCCATAGAAAATTCACCGGACAGGCGGGCCAAAGTGACGGAGATCTGCGCCTTCATCCAGAACCGCTTCCCCTACTACCGCAACCGAAAGGCCTGGCAGAAGTCGATCCGCGCCAACCTGTCGATGCACGAGTGCTTCATCAAAGTGTACAGTGGCAGAATCCGCAACAACTACTGGACAATCGATTCAAAATACAAGGACATGTTCGAGAACGGTAACTACCGACGTCAGTCTAATTGGTCGGTGGTATCGGATGCCAAGGCGGTCTCTCGCCCACACTACGTGGCGGATCCTGGGCACCGGCTGCAACACCCGTCAGCCGACTCTCAGCTGCCGGTCGACACCGAGGATTCGGGTGCAGACATTGGTAACGGAGATGGCACCGTGCTGCCATTCGCCTCCCCGCATCGCACCAGGTCGCCTCCAGTTTACGATGGAAGTAACACTGCATCCTTTGAAGAACAGAACGTTCAAAGTGCAGACCACAACGAAGTGGTAACGGAGCGAGAGGAGTCGACAGAAAGCATCAGTTGTGGTGTTTGGACACGAGACAGAGAGGATAATCCCATCTGTGGCACAGATAATATGAGGAAAATGGACAGTGACTTTCCTGCCTTCACCTGCAGTTCGTGCCTACAGAGCTTCTCATCAAAATACAGCCTCATAAAGCACGTGTTCACTCACATTGATAGGGTAGAGCCACCCTCACACATTTGTAGGGACTGTGGTGAAGTGTTTTCCTGTGATGACAGCCTGAATGAGCACTCGAAGATGAGGGGCAGTGGCAAGACGGGAAAGGTATGTAGCCCTAGTGGTACATCTAGAGACGAGACAATCACTGGTAACAATTCCTATAGACAAATTGCTAATATTGATCATTCACAGGGACACTGTTGTCAATCCAGTAACTGCTCTCTCTGTCAAGAGAGATCTACATCTCTCGTACACAAGAAGCCCTACAAGTGTAATGCATGTAGCAAATCCTTTGCCTTTTCTTGTTATCTTCGGATTCAGAAATGTGCAAACATGGATTACAGAAAAAAGCCACACGAGTGCGAAGTTTGTGGAAAATTGTTTCCTAAAGTTTACGACCTCAAGCTCCATTTATTAGTTCATTCTGGGTTGAAGTCCCTCAATTGTGATGTCTGTGATAAATTATTTGCCACAGTTGACGAACTGAAATTCCATTCTGCACTGCACTGTGTAGCGAACTCTCACAGGTGCGACATTTGTGACAAATCGTTTGACACGCTGGCGTCTCTCAAATCCCACGTCGTACGGCACTCCATAGTGGAGTCGCACAAATGCGACGACTGCGGCAAACTGTTTGCCAGGGTCGGTAAGTTTGAATTCCTCTTGTCAGTGCATTCTGGTACCAAATCCCTTGTGTGTAGTGTATGTAGCAAACCCTTTAAAAGTGCACTTAACCTCAGACGGCATATGCATATGCACACTTAA
Protein Sequence: MKENFCLTTDASNYGLGACLFQNINNEIRIIGFASRVLTSCERSYSTTELEALAIVWSLKKFHYYVFGKHVKIYCDHQALSFLLPCKLVHECLARWVLSIQEYSFEIIYIKGQDNVVADMLSRLPQGLPNYTKVIDQHLDFKIMIMKDEGNRKKFLTLCKNIVKLQEQDQRWTEIRQKLLADSNQNLSQHFRLNNQILYYRPHLDSEEWKLCIPEDSLETLILHTHKVWGHFGTSKCTAKLQHFYFPNLRKYVAKVFHTCSLCQRTKHLNQTNLSELHPIIPNKPLRIVSLDVSGPYPKSRAGVKYLVGIIDIFTKYLKLYAIKSISAKAIVKKLVQDYLPAIGKPTAILTDNASYFTGNVWKEFIQQNNIQHILISRFHPSANPIERSFRDFNRFVRTYVVHKKTKWFDLIGPYQQIVYNLPHITTNFTPTELLLNKQEDNEWVKVIPKNPSTVMPHQQKLDRAHENLQHKVRLRKMKFDSHLKKIQRFQLGEKVLLRNHPKSSLLKKLNSKWQYLYIGPFVITNIPHPGCYFLSYPKSLRPRGLYTHSDLRKYYMKSNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00912738;
90% Identity: iTF_00912738;
80% Identity: iTF_00912738;