Basic Information

Insect: Locusta migratoria
Gene Symbol: -
Assembly: GCA_026315105.1
Location: scaffold167315:199540-372052[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.022 2.3 9.1 0.3 2 23 439 461 438 461 0.96

2 16 0.0089 0.95 10.3 0.4 3 23 468 488 467 488 0.98

3 16 4.3e-05 0.0045 17.6 1.9 1 23 501 524 501 524 0.94

4 16 0.0013 0.13 13.0 0.3 1 23 530 552 530 552 0.98

5 16 0.0014 0.15 12.8 5.4 1 21 558 578 558 580 0.92

6 16 3.7e-06 0.00039 20.9 2.9 3 23 591 611 590 611 0.98

7 16 0.00031 0.033 14.9 2.7 1 23 617 639 617 639 0.93

8 16 4.2e-06 0.00045 20.8 2.8 1 23 645 667 645 667 0.98

9 16 0.0013 0.14 12.9 0.2 1 23 673 695 673 695 0.98

10 16 4.5e-05 0.0048 17.5 0.3 1 23 717 739 717 739 0.99

11 16 1.7e-06 0.00018 22.0 1.2 1 23 745 768 745 768 0.98

12 16 0.28 30 5.6 0.6 1 23 774 796 774 796 0.95

13 16 7.9e-05 0.0084 16.8 1.7 1 23 802 824 802 824 0.99

14 16 1.1e-06 0.00011 22.7 1.9 1 23 830 852 830 852 0.97

15 16 1.4e-06 0.00015 22.3 0.9 1 23 858 880 858 880 0.98

16 16 0.00066 0.07 13.9 3.0 1 23 886 908 886 908 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.022	2.3	9.1	0.3	2	23	439	461	438	461	0.96
2	16	0.0089	0.95	10.3	0.4	3	23	468	488	467	488	0.98
3	16	4.3e-05	0.0045	17.6	1.9	1	23	501	524	501	524	0.94
4	16	0.0013	0.13	13.0	0.3	1	23	530	552	530	552	0.98
5	16	0.0014	0.15	12.8	5.4	1	21	558	578	558	580	0.92
6	16	3.7e-06	0.00039	20.9	2.9	3	23	591	611	590	611	0.98
7	16	0.00031	0.033	14.9	2.7	1	23	617	639	617	639	0.93
8	16	4.2e-06	0.00045	20.8	2.8	1	23	645	667	645	667	0.98
9	16	0.0013	0.14	12.9	0.2	1	23	673	695	673	695	0.98
10	16	4.5e-05	0.0048	17.5	0.3	1	23	717	739	717	739	0.99
11	16	1.7e-06	0.00018	22.0	1.2	1	23	745	768	745	768	0.98
12	16	0.28	30	5.6	0.6	1	23	774	796	774	796	0.95
13	16	7.9e-05	0.0084	16.8	1.7	1	23	802	824	802	824	0.99
14	16	1.1e-06	0.00011	22.7	1.9	1	23	830	852	830	852	0.97
15	16	1.4e-06	0.00015	22.3	0.9	1	23	858	880	858	880	0.98
16	16	0.00066	0.07	13.9	3.0	1	23	886	908	886	908	0.97

Sequence Information

Coding Sequence: ATGTCTGTAAACTGTGCCTTGAAGTCTTGCGTAGCTCATGAAGCAAATCACGACACGTTGGAACTGCACTTTTTCCCGTTCCCGGAGGACGCAAAATTATGTGAACTGTGGATTAAGAAGTGCAATAGACTGGATTTGCTTAGCAAGCCCTACAGTGAAATTCACCGTACGCTGTACCTCTGTGAAAGACATTTTAGTGAAGATGCATTCGAATCGCCAAATGTCCTGAAACCTAACGCCGAGCCAAGTATTTCTATTCAAGATACTTCACCTACTCTAAGTGCCGATAAAACTGGGAATAGGATGGGTCCTGAAGTGGTAGTTATTCCTTACACCATCTCTGCCAACGAAGAAGAAATTGTGGAATATGGAGGAGGGGAAATTAAAGAAGAAGAACAGGAAGTTGCAGAAATAGAAACACGTTATGAAATAGCCGAAGGTGAGGTGTACATTGAACCGCTGGGAGAGAACTCTGCTGAACAAGGAGAACAGCAAGAAAGCCACTATGAAATAATTGATGAAAATGTCTTCGTCAGTCAAGAAACTGTGCAGGGGAATGATGAGACTGGGACTGATGATGCAAATATCAATAACTGTTTGGAAATGCAGAAGTCTAATGTTGTGGGAATAATAGTAGAAGAAAATTCCTATGACAGAGATGATTGGCAGCAAGGTCAAGAGGCAACCCTTGCTAATATATTGTGTCGAATATGTGCATCAGAAGAAGGAGAACTAATTCCGGTCTTTGGAGAGAAGGGTGAAGAGCTGCAGTTAATAGAAAAGATAAAATGGCATCTACCAATTGAGGTCAGAGAAGATGATAAACTTCCACTACAGATATGTATAACATGTATTGATAAATTAAACTCGTGTCATGAATTAGTCAGTTCTTGCTTGGAAGCTGATGCAAAGTTAAGAAAATTATTCTGCATTGAAGATGAAGAATCCATTGAAAAGAGGAATGATATACTGCAGTCATTTTCTGGCATGGAGGCAGAGCACACTGAAAGGAGAAGTAGAAAGAAGAACTACAGTTACAGTACAACTGATGGAATTGAAGATGAGCATCAGTTTGAAGATGGAGATGGTGAAGAATCTGAAGACAGTTCAAGGCTTAAAATGAATCATGCATATCAAATTGTGGATTCTGCAGGAGAGACTGAAGATAGTGATATGATGCAGATGCATGTGACAACTGAACTGACAGAGTGTGATCCTGGCCTTAAATCTAAAATAGCTGGTGCTATGAAAGACATAATGGTAAAAGATGATGTTCCACAATTTTTCAATAATGAAGAAGAAAATGCAATATGGAGATGTGATATGTGTGATTATGAAGCTTCCAAAAAATCTATTTTAATTAATCACATCAGGAAAAGACATGCTGCTGGTGCTGTAGCATGTAATTATTGTGAAAAATATTTTTTTGATGAAGAGTCAGCCAAACTTCACGAAAGAACTCACCTGAAATCAAAGGAGGACGATTCGGAGCCACCTATGTACGTGTGTGAATTCTGTGGGAAGTCATTCCGTGGACGAAAATCTTTGAAAGAACATCATTTAGCTAATCACAGTGAAGTGAAACCCTTCAAATGTGATCAGTGCGATAAAAACTACGGTTCGTTAGCTAGCTTAGACATCCATAAAGCGACACACTCTACAGAGACTCCCTATCTTTGTGATTTGTGTGGCAAGAGTTTCAAGCACATAAATAACTTAAGAAGCCATAAACGTTGTCATATGGATGACTCTTATAAAAATAGACAACTGTGTACAAAGTGTGGGAAAGGGTTTAGATCTAAGTTTCACCTCAATGAACATATGAATGTACACAATGGAGTCCGTCCATACAGTTGTGAGAAATGTGGTAAACGTTTCCATAAGAAGATACAGCTCCGCCAGCACGGCTCGGCTCATTTAGGTGAACAGCCATTTTCGTGTCATATCTGTGGCGTGAAGTTTAATCGACGTGGTAACATGACACAACACATTAAAAGGCACGAACACGAAAGAAAATACACGTGCAGGGTCTGCAACGAGTCATTCCCCACGTTGGGTGCCGTTCTTACTCATCGAAAGTTGCATACTGATCTAGAAGTAGAAAAAAGTATCCAGATGCAGGCAGGCGACGATCCCGAGCAGGCCGCCTTTAAATGTGTTATCTGTGGTAAACTTCTTGTCAAGAAGGAATCCCTGGCAACACACATGAGATCACATACTGGAGAAAAACTTTTTGAATGTACAGTGTGTGGAAAAAAATTGTCCAATAAAGGTTCTTTAACGTATCACATGCGGTCTTTCCACACCGGAGAGCGGCCTCATACATGCCAGTTCTGTGGTGAAGGGTTCCTTTCAAAGGAGGCACGCCTTGTTCACGAGCGAATACATACGGGAGAAAAGCCGTACAAATGTTCAGTGTGTGGTATGGCATTCCGTTGCTCCAGCAATCTGTCACAGCATGTAAAAGTACATTCAGAAGAACGCCCACACCCGTGTCAGCATTGTGGTAAAGCATTTCAGAGGAAAGGTGCCCTCGACGTGCATATGCGAACGCACACCGGTGAACGACCATTTACGTGTGATATATGTGGTAGAGGCTTCACACAAAAGAATGACATGCTTAAACATAGACGTATTCACACACAGGAGAAGCCTTTCCGTTGTGATCAGTGCGGTCATCTTTTTATGCAAAAACGAGATCTGACGAAGCACTTGAGCCTTCACTCTCATAAGCAGGAAGTTGTTGAGGAAGAAGAGACCCCTACACAGACAGTTGTAATAACGACAACTGATAATAATGTGATAACTTTTCCAGAAATACCAGTGAATGTACCTGTTATGGAAAATACTCAGACTGTTATCTTGCATAGGTTTTAG
Protein Sequence: MKPEEETNSRVVVFAAVPKPSDLCCIVAKVNVSEKRDSSAKSDYQWQILKCRQLIFSVPEIIASPVLGSQGWIYIITTKGNKATGRLEVHLQKFGLTEQGPIHLSNSIYEACLRYTLVAHIAPLWNQVDTYLIQGRDFLLSNCPLNAVKLEVAVKDEEVHLVIWPLRMKLPHLNLEDMEIIPSVCQDFFSHKISAISEMSIIPQWVHVLPSMKKGKVISVSHHLPESSPFKSYKELRRHWKNLYGYRLPESDEKLIYYNVFFMPLAPNQYSYPNVCICHMNAMIMKQVNFEAVLKEFLRDVNKKMPSVCGQSFILNCRLGYAIPKPMTLNQNLSLPNLSSSSRVQHKDLQRINPAFLKMTPVCSLEPECSITKSSEKKGKVQLAQAKGSPSGSKCISLMSSSEHAPTPAGVCSVLNCDLSNPTVADSAPDFQMQAAVNENCAEISNTNQIKYVPIFKKRVCVPYRRTLEGQHESTKNDINNSSSKYAEKCEQPTGQITTEKHPTALSQLLMQTHETSAPATLQVPVPSGQLQVKFIAHTLQNPLLNSVASLKRSVPTTSPSSTVPTNKKPRPRPQVQNDVDVEILARNNDLVKVNTVTLVSWLRQKNVPCKVKDKKGDLVEKVMNYLNNQKNESH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00912923;
90% Identity: iTF_00912923;
80% Identity: iTF_00912923;