Lmig004819.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Locusta migratoria
Gene Symbol
ERCC2
Assembly
GCA_026315105.1
Location
scaffold8330:651580-667363[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00016 0.017 15.8 1.5 1 23 247 269 247 269 0.96
2 16 1.1e-06 0.00012 22.5 1.6 1 23 312 334 312 334 0.98
3 16 6.1e-06 0.00064 20.3 4.2 1 23 343 365 343 365 0.98
4 16 0.00031 0.033 14.9 4.0 1 23 371 393 371 393 0.98
5 16 4.8e-07 5.1e-05 23.7 3.8 1 23 399 421 399 421 0.99
6 16 6.4e-06 0.00068 20.2 1.2 1 23 427 449 427 449 0.93
7 16 1.6e-05 0.0017 18.9 0.9 1 23 455 477 455 477 0.97
8 16 9.4e-06 0.00099 19.7 3.0 1 23 483 505 483 505 0.95
9 16 0.0021 0.23 12.3 1.0 1 23 511 533 511 533 0.95
10 16 0.00064 0.068 13.9 0.6 1 23 538 560 538 560 0.96
11 16 6.9e-05 0.0073 16.9 3.4 1 23 568 590 568 590 0.97
12 16 1.1e-06 0.00012 22.6 1.3 1 23 596 618 596 618 0.98
13 16 2.9e-06 0.00031 21.3 0.2 1 23 624 646 624 646 0.98
14 16 0.0006 0.064 14.0 1.0 1 23 652 674 652 674 0.94
15 16 0.0001 0.011 16.4 0.1 1 19 680 698 680 702 0.94
16 16 0.00014 0.014 16.0 2.2 1 23 707 729 707 729 0.96

Sequence Information

Coding Sequence
ATGCATGCTCAACTACTAAGCATCCACCCAGAACCTTCACAGAGTGAGTTTCCTGGAGCCATTGTGCAATCGCGGCTCAATTATGGGGCTGTACGGCCATCCTATTTAAAGATGCTGGACACGGTTCACCGTACAGGAATTCGGCTGGCCACTGGGGCATTCAGAACGAGCCCCATACCGAGTCTCTGTGCTGAGGCTGCCGAGCCGCCACTGAAACGTCATTTAACGGAAGCAGACAGGAATTGCCTGCTCAGATTTTATAGAGCCATTGTGCAATCGCGGCTCAATTATGGGTCTGTACGGCCATCCTATTTAAAGATGCTGGACACGGTTCACCGTACAGGAATTCGGCTGGCCACTGGGGCATTCAGAACGAGCCCCATACCGAGTCTCTGTGCTGAGGCTGCCGAGCCGCCACTGAAACGTCATTTAACGGTTACTCATGGAGTCGTCTCGTGTGACAGAGCGTCGGGAAGGACACCTGCTCTTGAGCATCAAATAGAAGTGAACCCAGCCAAACCATCCATCGACCCGTCTAACGACATCACAGCAAAATTCCCCAGTGCTACACAAGGAAATATTCTTCAAAAAGTGATACCCAGTGAGTCGGAGGTGAGCCCGAAAGCATCAAAATGTACTCTCAGCCGTGCCGTCGAAAGACGGCGAACTGTCTTTCAAGAGGACAACTCCTGCTTAACTGCAAATAACAAGAGATTGTCACAAGGTAAACTGGGCGTCTTCATCTGCAGTTCGTGTCAACAGAGGTTTTCATCGAAATACAGCCTCATAAAGCACGTGTTCATTCACATTGACGGTGTGGATCCACCATCACACATTTGTAGGTGCTGCGGTGAGGTGTACTTAACTCGTGTCAGTCTGCATAAGCACTTGATGGTGCAAAATCACGGAATAGTGCATTCTATTGAGAAACCTTACAAATGTTATGATTGCGGTAAATCGTTTGTTAAACCTAGTTTTTTCAAGGCCCACCAACAACTGCATTGTAGAAAGAATACACAAAAGCCGCACAAATGTGTCTTGTGTGACAAATCATTTACTACTGCTTATTACCTGAGGCACCACATCGTTACACATTCTGGGGTGAAGTTACACAAATGTGAGGTTTGTTACAAATCCTTTTACTCAGCTCTAGAGTTGAAGCACCACCAAATAAGTCACTCTGATCCGGGGCGATACAAATGCGAGGTTTGCGGAAAGTTTTTTGCCAGACCTCATCACCTGAGAGACCACAAAAGGATCCATTCTGGAGTGAAGGCACACAAGTGTGACGTCTGTGGTAAATTTTTCCGTACGGCTACCCAGCTGAGGAACCACGGAGTGGTACACTGTGAAGTGAAGCCTTACAGATGTGATGTCTGTGGGACACGGTATAGTACCATCAGCAATCTGAAATACCACACATTACTTCATTCCGAAGTCCCGCCTTACAAATGTGACATATGTGGTAAATTTTTTTCTAGACCTTCCCGCTTTAAGCAACACAAGTATCTGCATTGTGAACAGAAAACACACCAGTGTGACGTGTGTACTAAATTCTACGCTTCTGTCGACCTTCTCAAGCAACACAAAGTAGTGCACGAAGAGAAACTATACAAATGTCTCGTGTGTAGTAAATCCTTCCGTAAGGCTTTACTTCTGAAATACCATGAAGCAGTACATTCCGATGTACGAGTAAAGCAGCACGTGTGTGATACTTGCGGCAAATCATTTTTACACGCCAAAAGTCTGAAGCAGCATCTACGAATCCATTCTGATCTGAAGCCATACAAATGTGGTGTCTGTAGTAAATCGTTTCGTACACTTGGCTCTCTGAGAAGGCACAGAGTCACACATTCTGAAGTGAAACCGTACAAATGTGATGTTTGTGGCAAATTATTTGCCACAGCTTCTTATTTGAAGACCCATGCGCTAATCCATTCAGACGTGAAACCGCACAAGTGCGACAAGTGTGGCAAATCCTTTCTTAAGCTTGCCCTTCTGAGAAGGCATGCAGTAATTCATTCTGGTATTAAGTCATACAAGTGTGATGTTTGTGGCAGATTGTTTGCGAGGCGTGGCGACCTGAAGAGCCATGCTCCAATGCATTCCGAAAAGGTACACAAATGTGACGTGTGTTTTAAAACATTTTCTAGACCTCTTCTTCTGAAGCAACATTCGTTAGTGCATAGTGAGAAAGCACACATGTGA
Protein Sequence
MRLDVDGLPVYFPYDYIYPEQYAYMLELKKGLDAKGHCLLEMPSGTGKTISLLSLIVAYMANNPLDVTKLIYCSRTVPEIEKVIEELKKLVAYIEKQTEEKPRLLGLVLSSRKNLCIHPQVSKERDGKIVDGRCHSLTASYIRDRHSYDESVPVCNFYEAFNSFGREAPMAPGIYNLDDLKDYGRDMGWCPYFLARYAITHANIVVYSYHYLLDPKIAEIVSKELSKTSVVVFDEAHNIDNVCIDSMSVKITRRIVDKSTANIQLLERTIAEMKEDDAQKLKEEYQRLVEGLRDANLARETDIVLANPVLPDEVLQEVVPGNIRNAEHFVAFLKRFVEYLKTRLRVQHVVQESPAGFLKDVAQKVCIERKPLRFCHERLTSLLKTLEISDLTDFSPLVLVTHLATLVATYTKGFTIIVEPFDDKTPTVSNPILHFSCLDSSIAVKPIFDRFQSVVITSGTLSPLDMYPKILDFHPVIMSSFTMTLARPCLLPMIVSKGNDQVAISSRFETREDVAVVRNYGQLLVEVASNVPDGVVCFFTSYLYLESVVASWYDQGVVDNIQRHKLLFIETQDAAETSLALLNYIKACESGRGAVLLSVARGKVSEGVDFDHHLGRAVLMFGIPYVYTQSRILRARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRALRGKTDYGIMIFADKRFSRQDKRSKLPKWIQEHLKDSLCNLSTEEAIQIAKRWLRQMAQPFSRDDQLGVSLLTLEQLQNEEMRRNQQAAAEQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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