Lmig011046.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Locusta migratoria
Gene Symbol
trio
Assembly
GCA_026315105.1
Location
scaffold165770:741866-1019020[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 2.2e-06 0.00023 21.6 1.1 1 23 113 136 113 136 0.98
2 24 1e-05 0.0011 19.6 0.5 1 23 142 164 142 164 0.99
3 24 4e-06 0.00042 20.8 1.7 1 20 170 189 170 191 0.95
4 24 8.9e-08 9.5e-06 26.0 0.5 1 23 202 224 202 224 0.97
5 24 0.0012 0.12 13.1 4.9 1 23 234 256 234 256 0.99
6 24 5e-07 5.3e-05 23.7 0.8 1 23 262 284 262 284 0.98
7 24 2e-06 0.00021 21.8 1.2 1 23 290 312 290 312 0.99
8 24 8.3e-05 0.0089 16.7 2.7 1 23 318 340 318 340 0.93
9 24 1.4e-05 0.0014 19.2 1.0 1 23 346 369 346 369 0.96
10 24 3.7e-06 0.00039 20.9 0.4 1 23 375 397 375 397 0.97
11 24 5.8e-07 6.2e-05 23.5 1.7 1 23 403 425 403 425 0.98
12 24 1e-06 0.00011 22.7 2.0 2 23 432 454 432 454 0.97
13 24 1.4e-06 0.00014 22.3 0.9 1 23 647 670 647 670 0.97
14 24 1.6e-05 0.0018 18.9 0.7 1 23 676 698 676 698 0.99
15 24 1.4e-05 0.0015 19.1 2.6 1 20 704 723 704 725 0.95
16 24 3.7e-08 4e-06 27.2 0.5 1 23 736 758 736 758 0.98
17 24 9.8e-05 0.01 16.5 3.1 1 23 768 790 768 790 0.99
18 24 9.1e-06 0.00096 19.7 0.3 1 23 796 818 796 818 0.98
19 24 3.4e-05 0.0036 17.9 0.5 1 23 824 846 824 846 0.99
20 24 2.9e-05 0.0031 18.1 2.8 1 23 852 874 852 874 0.94
21 24 0.0007 0.074 13.8 2.8 1 23 880 903 880 903 0.96
22 24 1.6e-06 0.00017 22.1 0.2 1 23 909 931 909 931 0.97
23 24 2.2e-06 0.00023 21.7 1.7 1 23 937 959 937 959 0.98
24 24 1e-06 0.00011 22.7 2.0 2 23 966 988 966 988 0.97

Sequence Information

Coding Sequence
ATGACAGCTCTGAGCTTAAATCCTGCAGCCGACGATGAAGGTTGCAAAAGGCACATGCGTTACTGTGCACTAGCTGATGGAGCATTGACAGTGGTAGACAGAAGTAAATTGAACAACTCCATTGCACCTGACAACAACAAAGGAGAAACACAAACCGCAGCAAATAGTGTAGCAGAAAACTCAACAGAAGCACAAGATGATGGCAGCCTTCAACAACAGGTGAAAGGCATGATGCTGAGTCAAGTAAATGGGCTTAAAGATGAAACTTCAGCTTTGGGTCCGGGCAAATGTCATTGTTGTGGTGAAGACATTGACACTGCACATTCGGGAGGTGACTATGAATGTCTTGACTGTTCTAAAAGCTTCAAGTTGAAGTCCAGTCTGGAGAGGCACAAAAGAGTGATTCACATGGAAGGAGAAACATACACATGCCCAGAGTGTGACGCGAGATGTCCAGACAAAGGAACTCTTGCAAGACACATGTACACACATACTGGTCTGAAACCCTACTCATGCTTACAGTGCCAAAAAACCTTTAGCCGAAAATATCATTTGGAGCGACATATTGCACAAACAGGTTGTGATGGGAAGTTGAGGCAAAGGTTTCCATGTCAGGTGTGTGGGCGAATATTTACCCGAAAAGATAATTTGAGGCAACATCTCCGTGCTCATGCAGGTCAGGTAATACGCAAGAAGACTTACACTTGTGAACATTGTCATCATGAGTTCCAGGGTGCAACACTCTTGCAGGTGCATCTGAGGACCCATACAGGTGAGAAGCCATATCCATGTGATTTCTGTCCAAAGAGATTTACTTCAAGTGGTGCCTTGAAGAAACACCGGCGGATACACACAGGCGAACGACCTTTCGAATGCAAGGAGTGCTATGCCAAATTCGCAACAAAGGAAACACTGAATCGTCACATACGCACGCACACGGGTATCAAACCTCATATCTGCCAGTTCTGTGGCAAGAGTTTTATACAGTCTGCTCAACTTCGAGCTCATGTCTTCCATCACACAGGTGAAAATGGCTTCACATGTTCCCAGTGTGGCAAGGCATTCAATCGCAGATCTCGTCTAATTATGCATGTGAAATATGTTCATGAGGGTGCAAAACCATATGAATGTGAGCAATGTTCAAAAACATTTGTTCGAAAGGAAGATCTGGCGCGTCACACTATTCTACACTCGGGCATAAAAGCACACAAATGTCCAATTTGTCAAAAAAGCTTCGCCATGAAATCTTCACTGAAGATTCATCTTTTGACACATACAAAGGAACCACCCCGCTCTTGTGATGAATGCGGAAGAGCATTCATTCGTCAAGATTGTTTACTCCGCCACATGCGCACCAAGCATAGGGACATGTTGGAGGAAATATTGGCTGAAACAGAAAAGAAGAAACTGCAACAGCAACTTCTTGCTGCTGCAGCAGCTCAGGACAGTGTTGGATCTGGTGTGGGCTTGAATGGTAGGAGTGATGGAGGTCCTGGTAGCATACCTTCACTCAGTGAAGCTGCACTTGCTGATTCAGTCCGTGAACTGCTGGCACTGCTGGTTGACGAAGTGACTCTAAAGGCTTTTGGGATTAGTACACCAGCAAATTTTTCAGAATGGCTGAGGAACATGCAACTGAAGGGCTGCAAAAGGCACATGCGTTACTGTGCATCGGCTGATGGGTCATCTTCTGTGGTGGACAGGAGGAACATTGACAACTCTAGTGGACCTGAGAACAGTTTAGGAGAAAGTCAGATTTTAGATGAAAGTGAAGTTGATAACCCACCAGAACCACAAGACAGTGGCAGTCTTCAGCAACAGATGAAAGACATGGCACTAAACAAAGTAAATGGCTTTATTGATGAAACCCCAGCTTTGGGTCCAGGTAAATGTCACTGCTGTGGTGAAGATCTGGACACTGCACACTCGGGTGGTGACTTTGAATGTGTTGACTGTTCTAAAAGCTTCAAGTTGAAGTCCAGCCTTGAGAGGCACAGAAGAGTGATTCACATGGAAGGAGAAACATACACATGTCCAGAGTGTAATGCAAGATGTCCAGACAAAGGAACTCTTGCACGGCACATGTACACTCACACTGGTCTGAAACCTTATTCATGTTTACGATGTCAGAAAACTTTTAGTAGAAAATATCATTTAGAGAGACACATTTCACAAACGGGCTGTGATGGAAAGTCGAGGTCTAGTTACCCATGTCAGGTATGTGGGCGAATGTTCAGTCGCAAGGATAATTTGAGGCAGCACCTACGTGCTCATGCAGGTCAAGTAGTACGCAAGAAGACTTACACTTGTGAACATTGTCATCGAGAATTTCAGGGTGCTACTCTCTTGCAGGTGCATTTGAGGACTCATACAGGTGAGAGGCCATATGCATGTGATCTCTGCCCAAAGAGATTTCCATCAAGTGGTGCAATGAAGAAACACCGACGGATGCACACTGGCGAGCGACCTTATGAATGTAAGGAGTGCTATGCCAAATTTGCTGCAAGGGAAACATTAAATCGTCACATACGTACGCACACAGGTATCAGGCCGCATATCTGTCAATTCTGTGGAAAGAGTTTCATACAGTCTGCTCAACTTAGAGCTCACATCTTCCATCACACAGGTGAAAATGGCTTTACCTGTGTTCACTGCAGCAAGGCATTCAATCGCCGATCTCGCCTTCTTATGCATGTGAAATATGTTCATGAAGGTGCAAAACCTTATGAGTGTGAGCAGTGTCCAAAAACATTTGTTCGAAAGGAAGATCTGGCACGTCATACAATTCTACACTCAGGCATTAAAGCCCACAAATGTCCAATTTGTCAGAAGAATTTTGCAATGAAATCTTCACTGAAGATACATCTTCTGACGCATACTAAGGAACCACCTCGTTCTTGTGATGAATGTGGAAGAGCATTCATTCGGCAAGACTGTTTACTTCGTCACATGCGCACCAAGCATAGAGACATGCTGGAGGAGATATTGGCTGAAACAGAAAAGAAAAAACTTCAACAGCAGCTTCTGGCTGCAGCAGCATCTCAAGGCACTGGTGGAACTGGCGTGGGTCTGAATGGTAGTGGAAGTGATGGGGCATCAGACGGTTCTGGTATCATACCATCACTTAGTGAAGCTGCTCTCGCTGATTCAGTCCGTGAATTGTTGGCACTGCTGGTTGATGAAGCCACTCTAAAAGCATTTGGATGGCCAGAAACACAAGTTGACCAGTTGCTGGAGGCAGTCATTCGTCGATGTGGGCATCAACCTGTTACATCAGAGGAACTGTTGTACCCAGATAGATTGCGTGAAAATGCCAAGCTGCTGTTCACTGTTGTCATAGATGACTCTGCTGTCAAGACTTTGCTTAACAATCAGACTGTTGATGAAGTGATCCTGCATGTACTTCGTCTAGCCAAATCATAA
Protein Sequence
NTYTNAEKLLTAAEELAQTGECNADEIYSVARELESHVTSFAARVEQRRRRLDLAVLFYTHEKELSGWADELRGELVPDEAADTLEAAERLLEQCREQRASSLDACASTIAQGETLLQELRSAGVTPEMDATGSVAAVEAALGRLGKTRDELEALWDARKLRLDLCLRLRLFERDALEVSSQLDLWSDQLQRADTCRDAAQAEAMLRLHNESVARMQATTFAVLQQGQELAQAFETSGLSLMADSQYSAQTRVQVLLEFLHEREMDLEDLAELRRVKLEQCLQLCQFQADANQVVSWIRNGEAMLMASFAIPSCLQDAEQLKKEHEQFQVAIEKTHTSAVQVKHRAEALISANHYDPQSIREIAEEVTKRWQQLVTCAEERHKLVTASINFYKTAEQVCSVLDSLEREYKRDEDWCGSSTGTSSTSDKTDKATMVSQLINKHQEQKEAFLKACTLARRTAETFLKYTSRSLQYYNYQGEASSRNSENRVKNILEKLLSQENKVLEHWTQRKKRLDQCQQYVLFERSAKQAIEWIHETGEFYLSTHTNVGQNKEETETLLSEHNEFKGTAKETRERVKLLIQLADSLVEKGHAHASSIKQWVAAVDNRYKDFSSRMDKYRAQLESSLGIQEEGENRQDLSIDRNSDPLLETKLKEAANKELKELNEEKRKSARRKEFIMAELLQTERTYVKDLETCIKSFLDEMKSNPSVPGPIQGKDDIIFGNMEEIYDFHNSVFLKELEKYETMPEDVGHCFVTWAQKFDMYVKYCKNKPESNSLLVQHGGSFFEEMQKKHKVEHPIAAYLIKPVQRITKYQLLLKDLQSCCEEDQGEIKDGLDVMLNVPKKANDAMHLSLLEGCDMSSDKLGEVVLQDTFHVWDPKQIIRKGRERHIFLFELYLLFSKEVKDSSGKAKYIYKNKLMTSELGVTEHIEGDECKFAVWTGRAPISDYRIVLKASSLDVKQTWVKKLREVIQETYFSSALPLSMPKSPAKLKPGSQRSSRDLEDSASLDESVENLDRGSLASFGSGNTTDSDKAGGVEMTWVVADHVAAAGSHELSVSKGQQVEVVEAAAGDWCLVRVPSAGADSPPEGLVPLAVLKQPPTAAAAAKTTSPQRKPAAPTATDHDSEPGTSDGSSVGPATTNSPVNKRRVFSGRKWLPPPLRKLSQGSKVDKSAAAPAAAAAPADRPPLKKTASDKRFKLPSGEMGNKQAVAQPEGEESSAEERLAPAASSRPPFVDQNGEEPEDEVELPPPMKPISEPLVVAGAASADESQGKRSSSLSLKALEGATSADLAEIEQIVKERMEQHTENQERNSLLNRDSKVSSEMASDGEASTNTGSEGQGTCEEETADDKGGGVREGGEAQGSASGTAAAPSDSESVEDAAAAAIRKREYVIRELVETERDYVRDLEYVTEGYMSLMRNPDCEIPMPEDLRGGKDKMVFGNLEAIYEWHRDFFLKALEKCLSHPEELGPLFKRYERKLHMYVVYCQNKPVSEYIVSEYDIYFEELRQKLGHKLTLGDLLIKPVQRIMKYQLLLRDIYKYTERAKLQNEIDSLRIALQVMQVVPKAANDMMDVGRLQGFDGKITAQGKLLLHGPLVCCEGNSTFNFKGKELHVFFFEQNVIFSEAVGKKTQFSNPVYIYKAHIQVNKMSLEEVTDDCEPGKFIIRSTDPNKPNLSYVCQPTSKESCEEWVSTIRSILQTQKDFLKALQSPIDYQRGQEKKKEVSAPELSSVWTPSLRKSLSHPASSTEKENGRAYKNFDDSASLPCPSTAASALLDAYSVPSKAIYDSDQRSFTSSTDESHCSDKSNRTQSPTKMKLNFLEGFRNTLRSRTKSDVACYNECEWNSVKPSSPYAGSGTDKSIARRWSEAGTPNLVEAPPPNIIAPGTVVRVAVDFPAVHSDELTTYRGEHVQVVTYNADRNSYMVRRRSESSAPEDGWVPAHILMRTVSRKPWSFRFRKPGFSTGGRRGERRSFDGSLGPSPSSSGRVSPDSLIPEYPVAPPEFIEKLHCVNIHCGMRVELRCRICTPAGIGDFSDVNIVWRRSSNVQRLNPHDPGGSSILRTGGRLSISLMEDGTAQLVIENCQPSDAGEYSCTASNEAGSVTTSASLCITGTGLTSTMQPRVQVVTGTSVLLQWEGDSSSYYQVECYRHCLGDDWLPVGGPIRGLTHVVDGLTPGETYTFRVLSTGHGMSTPVASMPSSPIVIPPPDTGHWQQEQFRRRYSELEEIGYGRFSVVRKARDRGTSQEVAVKQVYCKRQSREVTQAEYALLARLQHSNIVRALALFENAPQPGIDSIVMELVNGPSLFSYLCKQVVYDEETVSHYMQQLVSALATLHQQNISHLDLKPENVLVDLSTTKPVLKLIDFGDSVSTRGSEVLPPSNLEFAAPEMVLGQPVCCQTDMWSVGVFLYVFLSGLSPFLDDSMEETTSNILKCDYCFPDEYFSEITNDGKDLIFRLLVLTPAQRASPAEFLSSPWFKDVQKICSIPTARLASFMERRQSLARPIHPIHASSQQQSPPE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-