Lcra004781.1
Basic Information
- Insect
- Lochmaea crataegi
- Gene Symbol
- topi
- Assembly
- GCA_947563755.1
- Location
- OX387422.1:36136943-36146400[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 1.3e-05 0.003 19.5 1.5 1 23 1246 1268 1246 1268 0.98 2 12 0.039 9.1 8.5 0.6 2 20 1275 1293 1275 1295 0.92 3 12 0.43 1e+02 5.2 0.3 2 19 1315 1332 1314 1335 0.84 4 12 0.0033 0.78 11.9 0.8 2 23 1387 1408 1386 1408 0.97 5 12 7.1 1.7e+03 1.4 0.9 1 12 1414 1425 1414 1427 0.89 6 12 0.0047 1.1 11.4 2.4 2 20 1451 1469 1450 1482 0.92 7 12 0.047 11 8.2 0.1 1 23 1576 1599 1576 1599 0.97 8 12 0.0052 1.2 11.2 0.1 1 23 1603 1625 1603 1625 0.97 9 12 5.4e-07 0.00013 23.8 0.7 1 23 1631 1653 1631 1653 0.98 10 12 0.05 12 8.1 0.1 1 23 1659 1684 1659 1684 0.96 11 12 0.00011 0.026 16.5 0.3 1 23 1718 1740 1718 1740 0.98 12 12 0.0002 0.046 15.7 3.6 1 23 1746 1769 1746 1769 0.98
Sequence Information
- Coding Sequence
- ATGAATGAATTTGTGGTAATTCTACAGGGGTACCTCAAAAAGATACTGAAGAAAATATTGCTGTGTAGATATTTGTTTGAAAAGAAAATGGAAGGGCATTTTAAGTGTTGTAAAAAAAAGGAATTTTCAAACTTAATGTGTATTGTTTGTTTTGATGTGTATCATTTCTCATGTTTGGATAGGAAAAAAGAATATAAGCTCATTGATCGTAATAAAATTTATTGCTCAGTAAAATGTGAAGAAAATGATCCAAAAATAGAAATTAACAAACTAAATGAAGAAGTAACTAGATTAAAAAATAAAATAAGAGAAAAGGATCTAGAATTAGAAAAAGTAGAAGGTGAAAATGTTGACAAAATGAATGACATGCAACAAGAAGTAAACGAGCTACACAAAGAAATAAAGGATAAAAATTGTTATATACTAAGAATGAAAAAAAGGACGCAGGACTTTGAAGATGAGGTATTTGAGTTAGAAAATAGTGATACCAAGAGAATAAGAGAGCAAGATGAAAAAATAAAACAATTAAATAGAGAAATTAAACAAATTGAAAATAAGTTAAAAGCGCAAGAGAAAGATTTACAAAGCGGAATTGATAACCAAGTTTTACTAAACAATAGAATTAAGGAAATGGATACTGTTAGTCGGGAAATGGTGAATGCAATACGAATTCTTGAGGAAGAAAATGATAGAACCAATGAAGAACTATCTAGATATAAAAAATTGGGAAATGAAAATAGGATAGGGCTGACAGAAACAACGCAAACAGTGCAACTATCAGATGGAGTAGGGAAAGCTATTAATAAACGAGACAGTGGAAAAGGAGGAAACATTAAGCAGAGGAAATTGTTAATACTGTGTGATGAAAATGGACGTAAGTTAAGAAAGACAATAGAGTTAGAATTAGAAAATTTAGGATATAAGGATTTTTTGTTAGAAACGATTATAAAACCGGGGGCTACTTATGAGAATGTTATTGCAAACATAGATGGACTAACAATTAATTACAATCTAAATGACTATGTAATTATATTGGGTGGTATAAATAATTTTAAAAATAATAAGTACCCGAGTGTACAGTTCATACATAATAAAATAAGACACTGTACACATACAAATTTGGTATTTGTCAAAATTCCAGAGGGAAACTTTCAAAAATATAGTAAAAAATATGTAAATAATTTCAACTTCAGATTTCAGGATTATATAAAAAGGCTGGACAATTATGCTCAAGGTTTCGCAAGGGTAATTGATTTATGTGATAGAAAGGGATTTTTTAATATTAATATGTATGGAAAAGTATGCAATAAGTTAGTTAATGAGATATTACAGGCAAAAAAGAATAATAATCTTGTATTCATTGAAACTCACCTCTTTTTTAGAAATAGCAAACAGCGAAAACGTCACAGCATAGAAAATAACTTTAAAAATAACTCTTTTATATTGTATCTAAATGCTCAAAGTCTTCCAGCTCATATAGATGATGTTAGGAATTTAGTTCAAACAAGAAAACCTTTAATTGTATGTCTATCAGAAACTCATGTTACAGAGGACATATTTAATTCTGAAATTAATATTAATAATTATGTTGTCCATAGGACAGACAGTAATAGCAGACACACGGGTGGAACTGCAGTATTTGTAGATAATAAATTAAAAATAGTTGATGTGCAGGGATATTGTATTGAGGGAGTGTTGTGGATAACTGGAGTGTCCATTATATTCCAAAATAAAAAATATTGGGTATTTGTTCTATATAGATCTCCAAGTAGTAGCATGATAAGATTTTTGCAATTATTTGAAGATTGGTTTGAAGAACATATCAAGGAGGAAAATGATAAAACTATTTTATGTGGGGATTTTAATTTGAATTGGCTAGATAAGGATAACAATTGCAGTTGTAGGCTACGAAGTTTTATAACGGATATGGGATTTATAAATTCAGTGACAGAATACACTCACTTAACAAAGGGGGGAGGTACATTAATTGATCTAGCTTTATCGAATTTAGAAATGGATGTAAGTGTTTTTGATTTCCCTAAAATAAGCTCTCACCGCAATATAGCAATATATTTAAAACACATAAAAgCGTTCATTCCAAATGATGAACAAGAAAATAATCTTAATATAATAGATATGGGTAATGGTGATTTAGTATCGGATATAAATGTAATACCAAATTGTTTAAATACATATTATGTTAAAAGTATTATGGATAAAGCAGAACAAATTGATAAAACTTTTACAAATAGTTTTCCAGTAGTAGATAAAGTTATTACTAATAAAATGACCACTTTTAATTTAATTAGTCTAGAGGAATTGGAAAAAATAATTAGTTCATTAAAGAATAAAAGTAGTCCTGATGATATCAGTGTAGAATTATTAAAAAAGTGTTTCAAAGATATTTTCATAAACGCTGCTCTAAAAAGGGTGCATATGTATTGTTGTGCAAATTTGTTAAAAATTAATATACAGAAAACAAAATGTATGGTATTGGGGGTAAAAGATAGGTATAGGGAAGTTAGTTTAAATATAAGATTTGGTGATGACACAGTGGAGACAGTAAAAAAATTTGTCTACTTAGGAGTAACTATTGACAATAATTTAAAATTTAAGGAGCATGCAAACCAAGTTATTAAAACTGTGGCCTATAAAATTAACTATTTGAGACGATGCTCTCCACATCTAAGCCAATGTCGCGATGCAAGCAAAATAACCCTGATATATTATAATTATGTTCACTGTTACGCACACTGTTTAAATTTAACTCTGGAAGATGCTTGCTGCTCTCACTCGAATAACAAGTTAATATTTGATTTTTTTGGAATTATTCAATGTGTTTATTCGTTTCTCGAAGGTAGTTGCGTAAGACATGCAATTCTAGAGAAAATAGCTAACAGTATAAATATGTCACTCAAGACATTGAAAATCGTTGATAATTATGAAATTTTGATATTAGCTCTTCAAGAAATTATTGAAACCTCCAAACAATCTGATGTTAAAATAAAAGCTGTAGGATTACTGGCGCAGTTGAAATCATTTAATTTCTTGATTTGTTTACATATGACTGCTCCTATTCTAGTAATGATACTCAAAGTAAGCAAAGCATTACAAACGGAAAATTTGAATTTACTGTCCGCAATCTATTCTGTGAAGAGTTTACAATCAAGTTTACAAAAATTGAGACTGGATTCTGAAACTTTTTTCAATAAAATGTATGTTGAAGTTGAAAAAATATTAGACAAACATGGTATTACAATTCCGGAAACTAGGAAAAGAAAAATTCCGCGTAAAATAGATCAGATGTGTGATAATCAACATGAATTTGGAAATATGAAAGATTTTGTTAGAATAAACACATTTTATCCATTTTTAGATTCACTTGTCTCCAGAATAGACCAACGTTTTAGTCAAGAAACGACAGACATTCTTAAAAGTGTGAACGAACTCTCTAATAGTCTTGGTGTACATAACTATAATACAAGAAATAAGGAAAATTTAAGAATTGAAATGTGTAGGAGAAGCAGTACATACCACTCTGTATTTCACAAAGGTATTAATTCTTTCAATAGTTTACCAGAATACATTAAACAAAGTTCATCTTGCGATAACTGTGACGGAAATATGAATACTGAATATCAATATCAAAGGCATCAGTGTGAATTTAATGCAGAAAAAGTTGTTTTAAAATCGGATGTTGATTCTAGTGAAACTGATGGCGGTATTCCCGTTAAATACATTTGCGAATTTTGCAATAAACAGTTTGTTAATAAAAATAATTTGGTTCGTCACCAGTCTAGCCACGAAAATACACAAGAAAATGTGTGTGAACATTGCAACAAACAATTTATTAGTGAAAATCGTTTAAGGATACACAAAGAAAACTATTGTAAAAAAGCTGGACACATTTCTAAATTTTACAGAAGCGATGTGGATGTTTGGAAATGCAAGAAGTGTTATGAAGTATTTTCTTCACCTTTATCAGCAAATTATCACACGACATCTTGTGTAGAAATCGTAGAAATCGAAGAAGATGAAGCAGAAAAAACAACACAATTATCGGACGAAGATAAAGTTGTCTTGACTAACGAAAATATTCACACCAAAGAAGCAATTGACAAGAAAAACATAGAAAAAATATCAACCGAGCTTCTACTACAATGTGAATTTTGTAACAGAACTTACGCCGAAAAAAAGGTTCTGCTTATACACCAAAGGAAACACACTACAGCCAGAAATTACGAATGTGTTAATTGCTTTAAAGTTTTCGATTCTTATCCAATAGCCGCCCAACATTGGATGAAAAAGTGTTCGGAATACGTAAATCTGTTTTACTTGCCAAAATTAACTTACTGTGAATATTGCGACAGAACATTCAAATCTCACGAACTACTCTACACGCACAAAATAGAAAATAAGCACTTTACTTACAAGCCTCATCTACGACAAACTGAAGAAACCAACAAAGATGTCGATGTTACAGTTCCCGAAGATAACAAAAATATCCTCAACAAACTAATCGACGACGATTTAAAAACTTTAGACGTCCCAGTTAACAAAATCCACTATCAAGGAACAGACGCAAATAAAGAGAATACCGGCGAACAACTTGAAAATTCTGTTGATACAACGGAAAAGGAGAAGAGAGGTAGAAAACGAAAATGGCCGACAAATCTGAGTGCGAGAACGATAAAACCGAGTCTTCAAGTCGACGACGGTTATAAATATCAATGCGAAAGGTGCATCGAAACTTTTATAAATGTTGACGATCTTGAGGAACATCGGGAGAAGGTACATGCTTCGAATTTCACTTGTGATGAATGTGGACAGGTTTTGCATAACGCCACAGCTTTGATAGTACACAGTCGTGCTCATAAGATGTTGAAACCGTATGTTTGTGAAACTTGCGGCCGAAGCTATACCAAACCTTCTCAACTTTGGCAACATATGCGCTTCCATCAAGGGATAAAGCCGTTTGCGTGCCCTCACGAAGGCTGTGAAGCGAGATACACGATACGTCCGGATTTGAAGGATCATATAAGAAAAGCCCACACTAGAGAGAGACCATTCAAATGCATCGTTTGCGATAAATGTTTTTTAACTGGTTCTGTTTATTACCAACACCGTTTGATACATGCCAATGACAGAAGATATGCATGTGATCTCTGTCCTAAACGGTTTTTTAGAGCCGATGCTGTCAAAAATCACCGAAGGATCCATACCGACGAACGCCCTTACCCTTGCCATGTATGCCGAAAGCAGTTTAGACAGAAAGGAGATCGTAACAAACATGTTAGGACTCAGCATCCTGTTTCAGTTTAA
- Protein Sequence
- MNEFVVILQGYLKKILKKILLCRYLFEKKMEGHFKCCKKKEFSNLMCIVCFDVYHFSCLDRKKEYKLIDRNKIYCSVKCEENDPKIEINKLNEEVTRLKNKIREKDLELEKVEGENVDKMNDMQQEVNELHKEIKDKNCYILRMKKRTQDFEDEVFELENSDTKRIREQDEKIKQLNREIKQIENKLKAQEKDLQSGIDNQVLLNNRIKEMDTVSREMVNAIRILEEENDRTNEELSRYKKLGNENRIGLTETTQTVQLSDGVGKAINKRDSGKGGNIKQRKLLILCDENGRKLRKTIELELENLGYKDFLLETIIKPGATYENVIANIDGLTINYNLNDYVIILGGINNFKNNKYPSVQFIHNKIRHCTHTNLVFVKIPEGNFQKYSKKYVNNFNFRFQDYIKRLDNYAQGFARVIDLCDRKGFFNINMYGKVCNKLVNEILQAKKNNNLVFIETHLFFRNSKQRKRHSIENNFKNNSFILYLNAQSLPAHIDDVRNLVQTRKPLIVCLSETHVTEDIFNSEININNYVVHRTDSNSRHTGGTAVFVDNKLKIVDVQGYCIEGVLWITGVSIIFQNKKYWVFVLYRSPSSSMIRFLQLFEDWFEEHIKEENDKTILCGDFNLNWLDKDNNCSCRLRSFITDMGFINSVTEYTHLTKGGGTLIDLALSNLEMDVSVFDFPKISSHRNIAIYLKHIKAFIPNDEQENNLNIIDMGNGDLVSDINVIPNCLNTYYVKSIMDKAEQIDKTFTNSFPVVDKVITNKMTTFNLISLEELEKIISSLKNKSSPDDISVELLKKCFKDIFINAALKRVHMYCCANLLKINIQKTKCMVLGVKDRYREVSLNIRFGDDTVETVKKFVYLGVTIDNNLKFKEHANQVIKTVAYKINYLRRCSPHLSQCRDASKITLIYYNYVHCYAHCLNLTLEDACCSHSNNKLIFDFFGIIQCVYSFLEGSCVRHAILEKIANSINMSLKTLKIVDNYEILILALQEIIETSKQSDVKIKAVGLLAQLKSFNFLICLHMTAPILVMILKVSKALQTENLNLLSAIYSVKSLQSSLQKLRLDSETFFNKMYVEVEKILDKHGITIPETRKRKIPRKIDQMCDNQHEFGNMKDFVRINTFYPFLDSLVSRIDQRFSQETTDILKSVNELSNSLGVHNYNTRNKENLRIEMCRRSSTYHSVFHKGINSFNSLPEYIKQSSSCDNCDGNMNTEYQYQRHQCEFNAEKVVLKSDVDSSETDGGIPVKYICEFCNKQFVNKNNLVRHQSSHENTQENVCEHCNKQFISENRLRIHKENYCKKAGHISKFYRSDVDVWKCKKCYEVFSSPLSANYHTTSCVEIVEIEEDEAEKTTQLSDEDKVVLTNENIHTKEAIDKKNIEKISTELLLQCEFCNRTYAEKKVLLIHQRKHTTARNYECVNCFKVFDSYPIAAQHWMKKCSEYVNLFYLPKLTYCEYCDRTFKSHELLYTHKIENKHFTYKPHLRQTEETNKDVDVTVPEDNKNILNKLIDDDLKTLDVPVNKIHYQGTDANKENTGEQLENSVDTTEKEKRGRKRKWPTNLSARTIKPSLQVDDGYKYQCERCIETFINVDDLEEHREKVHASNFTCDECGQVLHNATALIVHSRAHKMLKPYVCETCGRSYTKPSQLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKAHTRERPFKCIVCDKCFLTGSVYYQHRLIHANDRRYACDLCPKRFFRADAVKNHRRIHTDERPYPCHVCRKQFRQKGDRNKHVRTQHPVSV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -