Basic Information

Gene Symbol
-
Assembly
GCA_932525835.1
Location
CAKOAV010000047.1:1141318-1142448[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.34 20 6.0 0.7 1 23 39 61 39 61 0.91
2 10 0.013 0.78 10.5 0.2 3 23 90 111 88 111 0.94
3 10 0.00026 0.015 15.8 2.8 2 23 135 156 134 156 0.96
4 10 0.047 2.7 8.8 0.3 2 23 160 181 159 181 0.95
5 10 0.37 22 5.9 4.7 1 23 186 209 186 209 0.94
6 10 0.22 13 6.6 3.8 2 23 221 243 220 243 0.94
7 10 0.029 1.7 9.4 0.2 1 23 249 272 249 272 0.95
8 10 1.4e-07 8.4e-06 26.1 2.0 2 23 277 298 276 298 0.97
9 10 0.00019 0.011 16.3 2.3 1 23 304 326 304 326 0.97
10 10 5.1e-05 0.003 18.1 1.2 1 23 332 355 332 355 0.97

Sequence Information

Coding Sequence
ATGACATCGAGAGATCGCACGAGCGTTTGGCAAATGACCAAATCCGAGCGTCAGAATGCAGCCACATTTCTGGAGTGCACCACTGTCAAGCCGTTCTTCTACCAGCAAGCCAACTACAAATGCTTCTACTGCAACGAACTCTTCCCAGAAGTACAAGCAGTTCTACATCACACAGCCAGTCATACGACTCCAGAACGAACCGCGTTGCTGAAGGAATTCTTGATTAAAGGCAAAAGAGTCATCAAAGTAGACATATCGGGCTTAGCATGCAGACTCTGCCAGCAGAGATACTCCGATCTAGATGATATAAGGAAGCATTTGGGAACCGCTCATAAAAAAGAGTTCAATCCTGCGGGGAATGGTTTAATGGCTTACGATTTGAGTTCTACGAACGGGATGCTGTCTTGCCATAAATGCGCTAAGAGTTTCAACTCTTTCTTCTtattgaaccagcatatgaacgcgcatttcagcgtcgtatgcgagacctgcggactaggattcatgtcgcatcaaagattggtgaatcacaaaatagtccaccaaaacggggtccacaaatgtgacaaatgccaagacgtttttccaaccaaactaaagctcagataccacaccttcaagaagcatgaagtcaccaatctaaagaagattaagcctctgaaatgtccgcactgcttagagcggttttcggaacactacaagaagatgacgcatttgaaagaagtgcacggaatttcgtttactttcgactgtcaggtgtgcaaagctgtattaccgacgaggcgagcactgactgaacacacgactaaactccacacacagaggatccagtgcaaaatatgcgggaagtgcttcgggacccgatctctgctgaagatgcatatgcgagggcatacaggagagagaaacttcttctgcagcgtttgccaaaaagcatatatgcacgctaagactttgcgacagcatatgagcgtccatggagctgttttcaaattcacatgttcagaatgtgggaatgggttccagaatagaaatgagttTAACAAGCATATGAAACAATGGCATCCGCAATGGCAGTTCAAAACAATTGTGAAGAATTTCGGCGCTAACATCAGTGTGAATCCAACGTGA
Protein Sequence
MTSRDRTSVWQMTKSERQNAATFLECTTVKPFFYQQANYKCFYCNELFPEVQAVLHHTASHTTPERTALLKEFLIKGKRVIKVDISGLACRLCQQRYSDLDDIRKHLGTAHKKEFNPAGNGLMAYDLSSTNGMLSCHKCAKSFNSFFLLNQHMNAHFSVVCETCGLGFMSHQRLVNHKIVHQNGVHKCDKCQDVFPTKLKLRYHTFKKHEVTNLKKIKPLKCPHCLERFSEHYKKMTHLKEVHGISFTFDCQVCKAVLPTRRALTEHTTKLHTQRIQCKICGKCFGTRSLLKMHMRGHTGERNFFCSVCQKAYMHAKTLRQHMSVHGAVFKFTCSECGNGFQNRNEFNKHMKQWHPQWQFKTIVKNFGANISVNPT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01158205;
90% Identity
iTF_01170911;
80% Identity
-