Basic Information

Insect: Lobophora halterata
Gene Symbol: zfh1
Assembly: GCA_932525835.1
Location: CAKOAV010000033.1:10945874-10956808[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.022 1.3 9.8 0.2 1 23 86 108 86 108 0.94

2 8 4.1e-06 0.00024 21.5 3.0 1 23 119 141 119 141 0.98

3 8 1.8e-06 0.0001 22.7 6.2 1 23 150 172 150 172 0.99

4 8 0.00013 0.0073 16.8 1.0 1 21 178 198 178 199 0.95

5 8 0.0061 0.36 11.5 0.3 3 20 468 485 466 487 0.92

6 8 9.4e-06 0.00055 20.4 1.1 1 23 777 799 777 799 0.94

7 8 0.00016 0.0096 16.5 7.9 1 23 805 827 805 827 0.98

8 8 0.066 3.9 8.3 7.1 1 21 833 853 833 854 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.022	1.3	9.8	0.2	1	23	86	108	86	108	0.94
2	8	4.1e-06	0.00024	21.5	3.0	1	23	119	141	119	141	0.98
3	8	1.8e-06	0.0001	22.7	6.2	1	23	150	172	150	172	0.99
4	8	0.00013	0.0073	16.8	1.0	1	21	178	198	178	199	0.95
5	8	0.0061	0.36	11.5	0.3	3	20	468	485	466	487	0.92
6	8	9.4e-06	0.00055	20.4	1.1	1	23	777	799	777	799	0.94
7	8	0.00016	0.0096	16.5	7.9	1	23	805	827	805	827	0.98
8	8	0.066	3.9	8.3	7.1	1	21	833	853	833	854	0.96

Sequence Information

Coding Sequence: ATGAAAGTGCAGAGCTCGCTTATGGGAGTTGGCAGTTGGTACGAATGCTTGGCGGCCGGTTGGCTCGCGGACATGAGGAGTAAGCAAGTCCCCACCTCCACCACCTCGGCCAGGCGGCTCAAGGCCTTAATTCGTCCGCTGGCAGGCGGCGGTGGCGGCGGTGGCGGCGCGGGCGGGGCGGGCGGGGGCGGCGAGGCCAAGCCCGGGGAGGAGGAGGAGGAGCGCAGCGGCTCGCCGCTCGGGCCCGGCGGCCCCTTCTCGTGCGGCCAGTGCCGCGGCGCCTACCCCACGCGCGACCAGCTCGAGCGCCACGAGACGCTGCACTCGCCCAGCACTCAGGTGGATACACTCAAATATACATGCAAAATCTGCCACAAGTCGTTCGCGAACGTGTACCGGCTGCAGCGGcacatgataagccacgacgagagtgccaacctgcgcaaattcaagtgcaacgactgcgacaaggcgttcaagttcaagcaccacctcaaggagcacttgcgcatccacagcggggagaagcccttcgagtgtgccaactgcggcaagaagttctcacactccggcTCCTACTCCAGCCACATGACCTCTAAAAAGTGCCTCGTCATGAATCTCAAAATGGGTCGGATAAAGCCCAACAACCCCGCCCTGAACCCCGACCGGAGCCCGTCGCGCAAGCGAGCCAGCGCTATGGTCGCGTCGCAACTCAACAACAACATCGCCCCCAACGGTAACTCCTTCCTCTCCATCCTGCCCAAGTACAGCGAAGCCGCCGCGTTCCTGGCATCGTTATCCTCGCAGGAGCACCACTTCTACCGGCCGCCGATGAGCCAGCCCGGCATGAGCCCCTTCTACATGCCGCCTGGCGTGCCTGGCAGCCCCGCCGGTGCAACCGCGCCCTACAGCTTCCCCACGCCGCTCAGCCAGCTGTTCGAGCACTTGGCTTCCTCTCAATATCCCCAGAGGAATATCGAAAGTGCCGCTAGTCCGAGGCAAATGAGCCCGCGCCAGACCAACCCCGAAGATTTGATCGAAGAGGTGACGGAGGAGGATGACAAGCGCTCCGAGAGCAGCGCCGAGCTCGTCATGGACATCGAGGACGAGGAGGCCGGTGTTGTAAAAAAGGAGCGAGACGAGCGCGACGCTGACCTCGTATCGCCCCGACGCAGCTTCCACTCTGGCCCTTTGAATAACAATGCTGAAGATATTGATAATAAGCACTCCAGTTTCAATACGATACTTGAATCCGTAAGCGCTTCTGTCACGAATCATTTCTTCAGAGCTAATATGGAAAACCTCTCTCCAGTTTCTGGAAATATTTGCCCGAACATAGAGTCGCCGCTGACTCCTCATGTGATAGTCAAGGAAGAACCGCATACTGAGGAAACACAGAATTGTTTCAAATGCAACGCTTCTTTCGCCAACAAAAGCGATCTATTAGATCACGAGAAAGAGGTTTGTAACGGTCTATTTAGAAAACACGAAAGCTTAGCAGCTCAAGTGGCCGAAACGGTAGCTCTTAACAGGTTCGAAGCAGAAATTCGTGCCTCCGTACAGAGCGGCGTGAGCGCGAGTGAAGATGAAGAGTTCGGTCGAGACGAGCGCGATGAGAAGGGATCACTTCACGACAGCGACAGAAAGATACGTGTCCGCACCGCGCTCAGCGAGGAGCAGCAGGCGGTGCTCAAAGAACACTACTCCGTGAACCCGCGCCCCAACCGCGACGAATTCAAGCGAATAGCGCACCAGATCGGACTCGACAACAGAGTCGTCCAAGTTTGGTTCCAAAATAACAGAGCGAGAGTTCGACGAATGACCCAGTCCTCTTCGATGTCCGACCAGCCCCTAGATCTGTCGACAAAGAAGTCGAGCCCCTCGATGAGCTTAAGTCCGTCCCCTTCGCCGCCGTGCAGCATTTCAGTGACACATTCCGACTCGGAAGAAGCGGTCAACTTGAGCCAAAAGTCGTCGCGCAGCACGACACCGCAGCGGGCCGGCTACGTGAACGCGTACCCACATTCCAATTGTTCCTCGTCATCGTTCACCGACTTCCGGCTCTCGCCGTCCCCGGGTGAAAACTTGAACGGGCACAGACGGACGCTGGCGCAGAGGCTGAACCCGATGATGCCGATGGACAAACTGCTGCAGTACAACGACCTGGCGTCTGCGCGCTCGCCGCAGCTGGGCGCGCGCGGCCCCGCCAGCCCTGCCTACGAGCGCGCGCTCTGGGACGACGCGCCTGCGCCGCACGGCTACGACGACGACGCCACCGTGCTCAAGAAGAGCAAGCTGAAGGCCGAGTACAAGGAGGGCGAGGGGCAGTTCGTGTGTGACCAGTGCGACAAGACCTTCGTCAAGCAGAGCTCTCTCGCCAGGCACAAATACGAACACTCAGGGCAGCGTCCGTACAAGTGCGTACAGTGCCCCAAGGCGTTCAAGCACAAGCACCACCTGACGGAGCACAAGCGACTGCACACGGGCGAGAAGCCCTTCCAGTGCTGCAAGTGCCTCAAGAAGTTCTCGCACTCCGGCTCCTACAGCCAGCACATGAACCACAGGTTCGCGATCTGCAAGCCGTACCGGGACTGA
Protein Sequence: MKVQSSLMGVGSWYECLAAGWLADMRSKQVPTSTTSARRLKALIRPLAGGGGGGGGAGGAGGGGEAKPGEEEEERSGSPLGPGGPFSCGQCRGAYPTRDQLERHETLHSPSTQVDTLKYTCKICHKSFANVYRLQRHMISHDESANLRKFKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPDRSPSRKRASAMVASQLNNNIAPNGNSFLSILPKYSEAAAFLASLSSQEHHFYRPPMSQPGMSPFYMPPGVPGSPAGATAPYSFPTPLSQLFEHLASSQYPQRNIESAASPRQMSPRQTNPEDLIEEVTEEDDKRSESSAELVMDIEDEEAGVVKKERDERDADLVSPRRSFHSGPLNNNAEDIDNKHSSFNTILESVSASVTNHFFRANMENLSPVSGNICPNIESPLTPHVIVKEEPHTEETQNCFKCNASFANKSDLLDHEKEVCNGLFRKHESLAAQVAETVALNRFEAEIRASVQSGVSASEDEEFGRDERDEKGSLHDSDRKIRVRTALSEEQQAVLKEHYSVNPRPNRDEFKRIAHQIGLDNRVVQVWFQNNRARVRRMTQSSSMSDQPLDLSTKKSSPSMSLSPSPSPPCSISVTHSDSEEAVNLSQKSSRSTTPQRAGYVNAYPHSNCSSSSFTDFRLSPSPGENLNGHRRTLAQRLNPMMPMDKLLQYNDLASARSPQLGARGPASPAYERALWDDAPAPHGYDDDATVLKKSKLKAEYKEGEGQFVCDQCDKTFVKQSSLARHKYEHSGQRPYKCVQCPKAFKHKHHLTEHKRLHTGEKPFQCCKCLKKFSHSGSYSQHMNHRFAICKPYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00281695;
90% Identity: iTF_00909629;
80% Identity: iTF_00909629;