Basic Information

Gene Symbol
-
Assembly
GCA_932525835.1
Location
CAKOAV010000047.1:396509-397888[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.026 1.5 9.5 1.4 1 23 111 134 111 134 0.96
2 10 2.2 1.3e+02 3.5 0.0 2 23 161 183 160 183 0.87
3 10 0.003 0.18 12.5 3.4 2 23 206 227 205 227 0.98
4 10 0.018 1 10.1 0.0 1 23 231 253 231 253 0.88
5 10 0.00023 0.013 16.0 2.8 1 23 258 281 258 281 0.97
6 10 0.00016 0.0093 16.5 3.4 1 23 288 311 288 311 0.97
7 10 0.00017 0.0098 16.5 3.0 2 23 319 341 318 341 0.96
8 10 5.2e-05 0.0031 18.0 1.4 1 23 347 369 347 369 0.98
9 10 2.3e-07 1.3e-05 25.5 4.0 1 23 375 397 375 397 0.99
10 10 0.0029 0.17 12.5 3.7 1 23 403 426 403 426 0.98

Sequence Information

Coding Sequence
ATGTTGAATAATGTCGGCATCAAAGACGACGATGACGACGATTCCATAAAATTGGAGATAGATGAAGATGAGGATACGCCTATTGTAAAGCTAAAATGTCTCAAAGGCGCAGACACAAATGTTGTCGCTGTTAAAACTAAAATTAAACAAGCTACAAACAGCCAGTCGAAGAAAAATGAAAAGAACAAGATTCTCAAAAAGATTAAGACAAAACTCTCTTCAGATATTTCGCCGGAATCGTTAGAGCTCAACAAACAAAGATATAACATTCGAACTATAATGCAACACtcaaacgccacgcccatccgaactcacatcgtcggcagcggatacatttgctgtttctgcaaagcgtatttccctaaagctgcggacctcaaaacgcacaccatacgagaccacgaccaaccgacgaaaaataaattcatgcaaaaaacttttctgagcaaatacatggtgaaactggatatcacatcgctaaagtgcaccatttgcaacgcgctcgcggataccctcgaacgactcattgcccatctcaacgatactcaccagataggactccacacagacattaaaaatcatatcgttagtttcaaactcgacggagaagccatgaagtgtcacgtctgttcggtagaatataaaagtttcaaaaagttgcaagagcatatgaataaacatttttccaattatatatgtgacatttgtggcgcgggcttcatcaaccgtcagcagcttcttcctcacgcggatatacacaaagttggcgcgcacaagtgtactacctgtgagaaagtattccagtcagcaaaaaaactaaaggatcatgaacgagtcacgcatttgtcaatcacaggcgtgtacaagtgttatcaatgcggtagaaagttcaaaaataacaaggctaagaaagatcacatgaaagaaactcacggatctgaatttgccgaactgaagtgcgaagcctgtgataggactttcagtagtaatgattgcttgcgaattcacagaaacagatttcatttgttggagcgaagataccagtgtgaactgtgtgatcggagattctttacgtcaacccttttgaaagatcacagtataacgcacactggtttgcgaagttttaaatgtgaagtgtgcaccaaatgttactcgagaaaatccggcctaagagaacacatgcggatgcacaatggcgaccgccgattcaagtgttcctactgcgacatggcattcttgcaaaaatgcagcttgaaaggccatcttcgaagccgacacgatgcagaacttttgcaaacatAA
Protein Sequence
MLNNVGIKDDDDDDSIKLEIDEDEDTPIVKLKCLKGADTNVVAVKTKIKQATNSQSKKNEKNKILKKIKTKLSSDISPESLELNKQRYNIRTIMQHSNATPIRTHIVGSGYICCFCKAYFPKAADLKTHTIRDHDQPTKNKFMQKTFLSKYMVKLDITSLKCTICNALADTLERLIAHLNDTHQIGLHTDIKNHIVSFKLDGEAMKCHVCSVEYKSFKKLQEHMNKHFSNYICDICGAGFINRQQLLPHADIHKVGAHKCTTCEKVFQSAKKLKDHERVTHLSITGVYKCYQCGRKFKNNKAKKDHMKETHGSEFAELKCEACDRTFSSNDCLRIHRNRFHLLERRYQCELCDRRFFTSTLLKDHSITHTGLRSFKCEVCTKCYSRKSGLREHMRMHNGDRRFKCSYCDMAFLQKCSLKGHLRSRHDAELLQT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-