Basic Information

Gene Symbol
-
Assembly
GCA_932525835.1
Location
CAKOAV010000047.1:388499-391451[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.0067 0.39 11.4 0.6 1 23 88 111 88 111 0.94
2 18 2.5 1.4e+02 3.3 0.1 2 23 138 160 137 160 0.92
3 18 0.02 1.2 9.9 5.5 2 23 183 204 182 204 0.98
4 18 0.016 0.94 10.2 0.1 1 23 208 230 208 230 0.97
5 18 1.3 78 4.2 3.4 1 23 235 258 235 258 0.89
6 18 0.00057 0.033 14.8 1.1 1 23 265 288 265 288 0.95
7 18 0.045 2.6 8.8 7.2 1 23 295 318 295 318 0.95
8 18 0.0084 0.49 11.1 0.4 3 23 325 345 323 345 0.96
9 18 9.2e-07 5.4e-05 23.6 1.7 1 23 351 373 351 373 0.99
10 18 0.0067 0.39 11.4 0.6 1 23 481 504 481 504 0.94
11 18 2.9 1.7e+02 3.1 0.0 2 23 531 553 530 553 0.90
12 18 0.11 6.6 7.5 7.7 2 23 576 597 575 597 0.98
13 18 0.15 9 7.1 0.0 1 23 601 623 601 623 0.97
14 18 3.6e-05 0.0021 18.5 1.5 1 23 628 651 628 651 0.97
15 18 0.0064 0.38 11.5 4.0 1 23 658 681 658 681 0.91
16 18 0.19 11 6.9 4.1 1 23 688 711 688 711 0.95
17 18 3 1.7e+02 3.1 5.7 2 23 718 739 717 739 0.91
18 18 8.8e-07 5.2e-05 23.6 1.8 1 23 745 767 745 767 0.99

Sequence Information

Coding Sequence
ATGAAAGTAAAAATTAAAGTGTTGGATACTGACAACTCACGTTCAACTTTCGGCGATAAACCAAAAGCAACATCAGCTAAAAAACTTCCAACGAAGAACAAACAGAAATCGAAAACAACAGTTATTAAAAAAAAGATTACAAAGCAAGGAGCTAACATCGTTTCAGATAAGTTAAAGCTTATAAAGCACCTCTATAATATTCGGACTCTTTTGAAATATTCAAACGCAACTCCGATCCGAAACCACTTTACAGGAAGTGGGTATGTCTGTTGTTTTTGCAAAGCTGTTTTCCCGAAAGCCGCGGATCTGAAAACGCACACAATACTAGACCATGACGCCGTAACGAAGAGCAAATTTATGCAAAGATGCTGTCTCTCTTCATTGATAGTGAAACTCGACATCACATCTCTGAAATGCAACATGTGCAGCACACTCGCGGACTCTCTGGAACTACTCATAGAGCACCTTAACAATGTTCACCAGAAAGGATTCCACACGGACATCCCGAGCCACATCATGTGTTTCAAACTGGACGGAGAAGCGATGAAGTGCCACATTTGCTCGATAGAATGCAACAGCTTCAGATACCTACAACAACATATGAACAAACACGTCACTAATTTCATTTGCGATGAATGTGGCGCGGGGCGTATCAATAAGACTCTTCTTTCGGTACATACGAAGGTGCACGAAGTGGCCGATCATAAATGTATCACGTGCGGAAAAGTATTTCTCTCAGAGTTAAAGCTCAAACACCACATGAGCTTTGTGCATTTACACAGCACTAGCAAGTACAAATGTAACCAATGTGGTGAAAAATTCATAAATAGAAATAGGAAGAAAAAACATATGATCGCAGCTCACGGTGCCGTATTCGCAGATTTTAAATGCAATACTTGCTCGAAAACTTTCAAAAATTTCAAATGTATGCAAGAACACAAAGCCAAGTATCACTTGATGAAGCCACTCTTTTGTGGGATTTGTGATGGTACATTCTACAACACTGGACGCTTGAGGCGCCATGAATTGACCCACACGAACCCGCGAGGGTTCAAATGTGATGTGTGCTCCAAATCGTATTCGAGGAATGAGGGGCTGAAATATCACATGCGGTCTCATACCAGTATCTACATCAAGGACGAAAAAATCAAAACGGATAGAGATGATACAGAAAATCTAATGAGAGTTAAAATTGAGGTGTTGGATACTGACAACTCATGTTCAACTTTCGGTGATAAAAAAAAACTAACACCAGCTAAAAAGCGGACAACGAAAAACAAACCGAAATCGAAAAAGACAGTTGTCAAAAAAATGATTACAAAGCAAAGAGCTAACACCGTTTCAGATAGGTTAAAGCTTACAAAACACCGCTCTAATATTCAAACTCTTTTGAAATATTCCAACGCCACTCCGATCCGAAATCACTTTACAGGAAGTGGGTATGTCTGTTGTTTTTGCAAAGCAGTTTTCCCGAAAGCCGCAGATCTTAAAACGCACACAATACTAGACCATGACGCCGTAACGAAAAGCAAATTCATGCAAAGAGTCGGCATCACTTCATACATAGTGAAACTCGACATCACATCCCTAAAATGCAATATTTGCAGCGCACTCGCGGAATCTCTCGAACAACTCATAGAGCACCTCAACGATACTCACCAGAAGGGATTCCACACCGACATCCCGAGCCACATCATGTGTTTCAAACTGGACGGAGAAGCGATGAAGTGCCACATTTGTTCGGTAGAATGTAACAGCTTCAGATACCTTCAGCACCATATGAACAAACACGTCACTAATTTCATTTGTGTGCAGTGTGGCGCGGGCCGCATCAATATGGCACAGTTGACGATCCATGCCAAGACGCACGAAGTGGGTGCTCATAAATGCGACAGGTGTGGGAAAGTTTTTCTCTCGCCATACAAACTGCAGACGCACATACGTATGGTACACATATTCAGTACAGAAAAGTACAAGTGTTATCAATGCGGGGAAAAGTTCAACAACAGAAACAGAAAGAAACATCATATGATTTCCGCTCATGGAGCTGTGTTCGCCGACTTCAAGTGCAACGCTTGTCCTCAAACATTCAGGACATTTCAGTGTATGCAAGAACACAAGGCGAGATATCACATGACGAAACAGCCGCTGTGTTGTAAATTGTGTGATCGTACGTTCTACAGCACTGGACGCTTGAGGTGCCATGAACTTACGCACACGAACCCGCAAGGGTTCAAATGTGATGTGTGCTCCAAATCTTATTCGAGGAGGACTGGGCTGAGAGATCACATGCGTTCTCACGCAGTGTGA
Protein Sequence
MKVKIKVLDTDNSRSTFGDKPKATSAKKLPTKNKQKSKTTVIKKKITKQGANIVSDKLKLIKHLYNIRTLLKYSNATPIRNHFTGSGYVCCFCKAVFPKAADLKTHTILDHDAVTKSKFMQRCCLSSLIVKLDITSLKCNMCSTLADSLELLIEHLNNVHQKGFHTDIPSHIMCFKLDGEAMKCHICSIECNSFRYLQQHMNKHVTNFICDECGAGRINKTLLSVHTKVHEVADHKCITCGKVFLSELKLKHHMSFVHLHSTSKYKCNQCGEKFINRNRKKKHMIAAHGAVFADFKCNTCSKTFKNFKCMQEHKAKYHLMKPLFCGICDGTFYNTGRLRRHELTHTNPRGFKCDVCSKSYSRNEGLKYHMRSHTSIYIKDEKIKTDRDDTENLMRVKIEVLDTDNSCSTFGDKKKLTPAKKRTTKNKPKSKKTVVKKMITKQRANTVSDRLKLTKHRSNIQTLLKYSNATPIRNHFTGSGYVCCFCKAVFPKAADLKTHTILDHDAVTKSKFMQRVGITSYIVKLDITSLKCNICSALAESLEQLIEHLNDTHQKGFHTDIPSHIMCFKLDGEAMKCHICSVECNSFRYLQHHMNKHVTNFICVQCGAGRINMAQLTIHAKTHEVGAHKCDRCGKVFLSPYKLQTHIRMVHIFSTEKYKCYQCGEKFNNRNRKKHHMISAHGAVFADFKCNACPQTFRTFQCMQEHKARYHMTKQPLCCKLCDRTFYSTGRLRCHELTHTNPQGFKCDVCSKSYSRRTGLRDHMRSHAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-