Lhal009303.1
Basic Information
- Insect
- Lobophora halterata
- Gene Symbol
- zfh1
- Assembly
- GCA_932525835.1
- Location
- CAKOAV010000020.1:2376206-2380333[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.0001 0.006 17.1 1.0 2 21 188 207 187 208 0.94 2 19 0.074 4.3 8.1 0.2 3 23 214 234 213 234 0.94 3 19 1.6 94 3.9 0.1 3 23 241 262 239 262 0.95 4 19 5.7e-05 0.0034 17.9 0.5 1 23 267 289 267 289 0.97 5 19 1.5 89 4.0 4.1 1 20 292 311 292 313 0.91 6 19 0.0039 0.23 12.2 1.9 1 23 325 348 325 348 0.93 7 19 0.00041 0.024 15.2 2.3 1 23 354 376 354 376 0.98 8 19 0.26 15 6.4 2.1 5 23 386 404 385 404 0.97 9 19 0.025 1.4 9.6 0.6 1 23 410 433 410 433 0.97 10 19 5.2 3.1e+02 2.3 0.1 3 15 443 455 443 458 0.88 11 19 0.0015 0.086 13.5 0.7 2 20 573 591 573 593 0.94 12 19 0.0054 0.32 11.7 0.9 3 23 628 649 626 649 0.92 13 19 0.00042 0.024 15.2 0.3 1 23 654 676 654 676 0.97 14 19 0.03 1.8 9.4 2.2 2 20 680 698 680 700 0.92 15 19 0.0022 0.13 12.9 0.4 1 23 726 749 726 749 0.95 16 19 0.00053 0.031 14.9 0.9 1 23 755 777 755 777 0.96 17 19 0.0032 0.18 12.4 0.2 1 23 783 805 783 805 0.98 18 19 0.0095 0.56 10.9 0.2 1 23 811 834 811 834 0.94 19 19 6.9e-05 0.004 17.7 0.2 2 23 841 863 840 863 0.91
Sequence Information
- Coding Sequence
- ATGGAGGAGACATCAGTGATGCCCCAGCAATTGTGCACTCACTGTGTGTCTCACATCACCAGCTTTCTGCCATTCTTCAAAATGTGCCGAGAATCTATCGCTCAATGGAACCGCATATCCGAACACCTGATCAAAACATCCGTCCACACGAAAGCTAGAACAGCATTTATCCTCGTTACAGACGACGGTATAAAAACTGTGGAACGAAAGGATGCTGTGAACAAATCACTGAAACACGTTGAGGAAGACGCCAGCCTACCGCCGGGGCTGTGCCACGCATGCTCCGGAGACGTCCTAGTCGCCGCCAATTTCAAACACTTATTTGACAAATCCACAGAAAACTGGGATGACGCTACCAATTACCTTTCCACAATTAACATTGAAACAGAGGACAAAACTGTTATCCTTCTTTGTGATGACCATCTAGATGACCACGACGTGATTTTGTGCAAGAAAAGGTTGGATAGTGTCGAATCGGCTGTGACTACACTAAAGAGGTTTCAAAGGAAACGAAAACAGATGCGGCACCAAAAACAAAAGCGATCGAACACAATACCGTCCACATGTCCATACTGCAACAAAGAGTTCACATCTCTTAACCAATTGAACGAACATCTGAAACATGGGGATAGCCAAGCTTGTACGATTTGCGGCGAAGTGTTGAAGAAAAATGACCTATCTAAGCATATTCTTCAATATCATGATATAGAAACGATAGACTGCAAGATTTGCTTCAATCTATTCGATAGTTACGGAGATGCGAATTGGCATATTATGCGATACCATGGACCGAAATCGTTTACTTGTAAAGTTTGCGGCAGAGGGTACCGAAATGAGAGAGGCTTGCGAGCTCATTTGTACTCACATTCTCTCTTTTGTTGTAACGCTTGCGGGGTAACTTTTGAAAACAACGCTTGTTACAAATACCACAAAACAACTTGCAAAGAAACCAAACTTAAAATTGATGAACTTTACGAATGTCATCACTGCGGGTTGCAATACGCGCTCAAACCTTCCCTCCGCACACATATCGTCCAAAAACATCTGAATGTCCTCCCATACGTTTGCCAAACGTGTGGAAAACGTACATCGACGATCACTCACTTAAAATCGCATGAAGATACGCACTCAACAGATCGAAAGACTTTCATATGTCACTGCGGGGCTAAATTCCGCACTCTATTAGGCTTTAAACTTCATTTGAGGATTCACTCGGGAGAAAAGCCGTATCGATGTGATCAATGTGGAGACAGCTTTATATCAGCGTCTAGACGATTGGATCATATCAAGAGAAAGCATAAACCTACAAAAGATATGGCTCACGGATGCGACCGATGTCCCGCCAGGTTTTCCCGAAATTATCTGATTACCGTTCTGTCTCATTCTTTCCAGATATCAGATGAAACTCTCTGCCCCAATGGCGTTTGCGAGACGTGCGCCAGCGCAGCGCTCGCAGCTGAGGAATTCCGACTATTCGTTCAAAACGCAGAAAAAATGTGGCATAAAGCAATATCTAATTTAGAAGACGTGCCGTTAGAGTACAATGAACACGCCAAATCTATCTGCGCTTACCTATCGCAAAATGAACTATCCATGGAGATATACAAAGACTACAGTGGAGGAGAGCCTGAAACTGTCGTCAACAGATCTAAATCTAGGGCTCATAAGAAGATAGAAAGGAAACCTAGAGTCCTTCGCGGCGTAGGGCCGGTGGCAACGTGTCCGGACTGCCACAAACTGTTCCCAAGCCCTCATCTTCTACACGCACATTTGATAAACAGCGAACAGAAAGATGCTTGTCTCGTATGCGGGATAGTTAAAGCCAAAGGCATCGAAATGAAGGAGCATATGGAGTCAGTCCATAACCAAACCACGTGTCTGTGCAAGCAATGCCCTTTGATATTCAACACGGATTCAGAACTTAAAAAGCATGTGGCAAACGCGCACAAATCTGGAGCGTTTGCATGTAACGCTTGCGGGAGGATATTCCCAAGAAAAACGTCCTATGATAACCACATACAAATGCATTTAGTACGGACTTGTAGATCTTGTGGTCAACAGTTCACGAATAGAAGCTGCTATCGAGCACATAGATCCGTATGCGAACCAGATGCTAAACCACCATCTAAAGCAGTACCCAGGAATAGACGCTCGAACTTACGAGACCCCGGGAACTACATTTGCGATTACTGCAATAAAAAGTACCTGTCCAGACCCCAATTGAAGAACCATATTCTCTGGATACATTTAGACCACCGGCCGCATCAATGCAGTTGGTGTGGAAAGAGGTTTTTCACGGCGGCTAGGTTGAATGAGCATACTGTTGTACATACGCGTGTTAGAAAATTTGAGTGCGATTTGTGTGGACTTAAACTGGTTTCCAAAAGTGCTGTGATATACCACAGACGGCGGCATACAGGCGAAAAACCTTACGTTTGTGATGATTGTGGAGCCGCCTTCATATCTTCCTCAAGGAGGTCGGAACACGCTAAAAGAAAACATAATAAAGGAGTCAAATTGCAGTGCCCTGAGTGTCCGGCCTCGTTTGTTAGAAAAAATGAGCTGAAGAAGCATAACGACAAAGTCCATGGAATTGTTGAAATAGTTGTTCCAATGTTTATGCAGTAG
- Protein Sequence
- MEETSVMPQQLCTHCVSHITSFLPFFKMCRESIAQWNRISEHLIKTSVHTKARTAFILVTDDGIKTVERKDAVNKSLKHVEEDASLPPGLCHACSGDVLVAANFKHLFDKSTENWDDATNYLSTINIETEDKTVILLCDDHLDDHDVILCKKRLDSVESAVTTLKRFQRKRKQMRHQKQKRSNTIPSTCPYCNKEFTSLNQLNEHLKHGDSQACTICGEVLKKNDLSKHILQYHDIETIDCKICFNLFDSYGDANWHIMRYHGPKSFTCKVCGRGYRNERGLRAHLYSHSLFCCNACGVTFENNACYKYHKTTCKETKLKIDELYECHHCGLQYALKPSLRTHIVQKHLNVLPYVCQTCGKRTSTITHLKSHEDTHSTDRKTFICHCGAKFRTLLGFKLHLRIHSGEKPYRCDQCGDSFISASRRLDHIKRKHKPTKDMAHGCDRCPARFSRNYLITVLSHSFQISDETLCPNGVCETCASAALAAEEFRLFVQNAEKMWHKAISNLEDVPLEYNEHAKSICAYLSQNELSMEIYKDYSGGEPETVVNRSKSRAHKKIERKPRVLRGVGPVATCPDCHKLFPSPHLLHAHLINSEQKDACLVCGIVKAKGIEMKEHMESVHNQTTCLCKQCPLIFNTDSELKKHVANAHKSGAFACNACGRIFPRKTSYDNHIQMHLVRTCRSCGQQFTNRSCYRAHRSVCEPDAKPPSKAVPRNRRSNLRDPGNYICDYCNKKYLSRPQLKNHILWIHLDHRPHQCSWCGKRFFTAARLNEHTVVHTRVRKFECDLCGLKLVSKSAVIYHRRRHTGEKPYVCDDCGAAFISSSRRSEHAKRKHNKGVKLQCPECPASFVRKNELKKHNDKVHGIVEIVVPMFMQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -