Basic Information

Insect: Lithophane leautieri
Gene Symbol: THAP3
Assembly: GCA_949152455.1
Location: OX424488.1:3576125-3598174[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.25 19 6.6 1.2 1 23 358 380 358 380 0.92

2 11 0.0023 0.18 13.0 1.2 1 23 387 410 387 410 0.93

3 11 0.33 26 6.2 0.2 1 23 414 436 414 436 0.92

4 11 0.13 10 7.5 0.9 1 23 441 464 441 464 0.97

5 11 0.0035 0.27 12.5 0.3 1 23 468 491 468 491 0.96

6 11 6.3 4.9e+02 2.2 0.1 2 19 503 520 503 523 0.78

7 11 1.2 94 4.5 0.2 3 23 579 600 577 600 0.94

8 11 0.0047 0.37 12.0 0.6 2 20 616 634 615 637 0.92

9 11 3.5e-05 0.0027 18.7 3.1 1 23 643 665 643 665 0.99

10 11 0.00027 0.021 15.9 2.8 1 23 672 694 672 694 0.98

11 11 0.0038 0.3 12.3 4.0 1 23 700 723 700 723 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.25	19	6.6	1.2	1	23	358	380	358	380	0.92
2	11	0.0023	0.18	13.0	1.2	1	23	387	410	387	410	0.93
3	11	0.33	26	6.2	0.2	1	23	414	436	414	436	0.92
4	11	0.13	10	7.5	0.9	1	23	441	464	441	464	0.97
5	11	0.0035	0.27	12.5	0.3	1	23	468	491	468	491	0.96
6	11	6.3	4.9e+02	2.2	0.1	2	19	503	520	503	523	0.78
7	11	1.2	94	4.5	0.2	3	23	579	600	577	600	0.94
8	11	0.0047	0.37	12.0	0.6	2	20	616	634	615	637	0.92
9	11	3.5e-05	0.0027	18.7	3.1	1	23	643	665	643	665	0.99
10	11	0.00027	0.021	15.9	2.8	1	23	672	694	672	694	0.98
11	11	0.0038	0.3	12.3	4.0	1	23	700	723	700	723	0.89

Sequence Information

Coding Sequence: ATGAGGTGCAGTGTTCAAAATTGTTCTAATGACACAAGAACAACTAACAAAAGCCATGGAATCACATTTCATATGTTTCCGAAACAGCTGGACCTCCGCGCTGCCTGGGTGGAGGCTCTGGGCATGTCTGACTGGGAGCCCAAAGACAGAAGCACCATATGCTCCGAGCACTTCCGGAGTGATGACATCTATGAGACAAAGGGTGGGTTGAGAAAGATAAAGTGCGGAGCAGTGCCTGTTGTGACAACTCACTCCGCAGATGACCTTGAAGCACCAGCCGCATTGAGGGTGTGCCGAATATGCCTTGTAATGGACAGAAAGATGTATCACATAAGAGAGTTAAAATTGGATCAAATGTACGAGCAGATCACTGGCTTGATGGCTAGTTCAGAAGAGTGCCTACCGCAGCGTGTGTGCTGGGAATGCGCCGCTCGTCTGAACTCGGCGTGTCGCTTCAGAAATAAGGCTCTACGCAGCGATGCTTTGTTACATGATATGCTGCAGACAGACTCTTATATAAAAATCCGCGACATAAAATCGGTTAACCGAAAACACAACCACCTCAGTTCCACGTTAATACATCAGATTTATGAAAATGATGATTTCGACCTTCGCATCAAAGACCTTTCTAGCATCAAAACAGAAGAAATACCGGATTCATCCGAAATTATACCTATTACTACCGAAGAAATTGACGTCAAAAGCCTAGCACCTATAAATGAAGTCGAAATTAAAGATGAAAGTAGTAGTAATGAGATATTTTTTGAAGAATACGATCATTTTGATGACGAGGATGATAAGTTGCTAAGTGAGGTTTATGTGGAGAAGAAAGAAAAGCCAAAAGTTAAGAAAAAGAGAGAAAAGATTGTAAAAAAAGTAAAGCCGAAGAAGGTGGAGGAAGAAGATGATCCCGACACTACCAGTGATAAgtacaaaaaaaatgacGTAAAACGTCGTCGAAACAACGAAGCCTTCGACGAGTCGTTGTTCACAATCACTTCACTGACTTACGACCAGCAGATAGAAGAAATATTGAAAAGACAAGAGAGTTACAACTATACAAGCGCGCCTTACAAATGTACGATATGTTATCGAGGATTCCAAATCAGGGATCGGTTTACCGCCCATTCTGTGAGGCATACTGAGCAATGCGGTGCGTACGAATGTTTTATCTgcaaaactagactaaaaactAGTCGCGCGCTACGGAAACATCTAACGGCGCAACACACAGAACAATATAGTTGTAAAGGTTGTCCATTTGTCACTAGAAATCGAGGTGTAGCGAGAGAACATGAGAAGTGGCATGCGGGGACTAAATACCAGTGTCCACACTGTGCCAGCGAGTTTGATAAAATAACAACATATATGGGACATATTCGTATCAAACATGTGTCGGATTTCGTATGTGAACTCTGTGGGTACACGTTTGTCAGTGAGAAGGGCATCGCTGTCCATAAGAAGAAGAAGCATCGGATTGATAAAGCGTTAACATTAGAAGGGCCCTACTGTGAGCTGTGTGACGTGAAGTTCGTGTCGGAAGAGGCTCATGACAGACATCTGAAGCTATCTTCAAAACATAGCAGTGATCATGACCCTAACCGAATCCGGAACGACTCTCAAAGCATGAACGCAGAACGCAACGGTCGCGTTATGCGTCGCATTGAGAGGAGGCCGGTCATACACCCGCGCTTACCGAGCGACAGCGATCATGAACCGCACACACCCGTCAACTGCGAACAGTGCGGCATGCAACTTCGCGACCTGCGAGTGTATGCGCAACACTTTCGTCGAGCTCACCCGGACAAGAACCGAACCAAGTACCCCGCGATGAAGACACCGTGCATGTGTGAGCAGTGCGGGAAGATATTCCAGAGCATGGCCCTTCTCAAAGACCACATGTGGGTCCACACCGGTGAAAAACGTTTCAAATGTGACCGCTGCACTAAGAGCTTTACCCAAAAAACAAACCTCGTGTTCCATATGAGGGTCCACAGCGCCACACGACCGAGCTACGAGTGTCCGCTGTGCGGGAAACACTTCGCGTTCTTCAATAACAGAAGACGACATATGTTTATCCACACCGGCTTGAAGCCCTTCAAATGCGACACGTGCGGCAAATGTTTCACTACAGCGGGCGAACACAGGGCGCATGTTGAACACGTGCATCTGAAGAAGCCCTGGCCCAAGCGGGCGCGCCAGAGACACAGGGACTGGAAGTGTGATGACCCCAGTGTTGAGGACTGA
Protein Sequence: MRCSVQNCSNDTRTTNKSHGITFHMFPKQLDLRAAWVEALGMSDWEPKDRSTICSEHFRSDDIYETKGGLRKIKCGAVPVVTTHSADDLEAPAALRVCRICLVMDRKMYHIRELKLDQMYEQITGLMASSEECLPQRVCWECAARLNSACRFRNKALRSDALLHDMLQTDSYIKIRDIKSVNRKHNHLSSTLIHQIYENDDFDLRIKDLSSIKTEEIPDSSEIIPITTEEIDVKSLAPINEVEIKDESSSNEIFFEEYDHFDDEDDKLLSEVYVEKKEKPKVKKKREKIVKKVKPKKVEEEDDPDTTSDKYKKNDVKRRRNNEAFDESLFTITSLTYDQQIEEILKRQESYNYTSAPYKCTICYRGFQIRDRFTAHSVRHTEQCGAYECFICKTRLKTSRALRKHLTAQHTEQYSCKGCPFVTRNRGVAREHEKWHAGTKYQCPHCASEFDKITTYMGHIRIKHVSDFVCELCGYTFVSEKGIAVHKKKKHRIDKALTLEGPYCELCDVKFVSEEAHDRHLKLSSKHSSDHDPNRIRNDSQSMNAERNGRVMRRIERRPVIHPRLPSDSDHEPHTPVNCEQCGMQLRDLRVYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGKIFQSMALLKDHMWVHTGEKRFKCDRCTKSFTQKTNLVFHMRVHSATRPSYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDTCGKCFTTAGEHRAHVEHVHLKKPWPKRARQRHRDWKCDDPSVED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01441464;
90% Identity: iTF_00449181;
80% Identity: iTF_00906223;