Basic Information

Insect: Lithophane leautieri
Gene Symbol: -
Assembly: GCA_949152455.1
Location: OX424469.1:3542280-3554557[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.048 3.8 8.9 0.4 1 23 263 285 263 285 0.98

2 10 0.038 2.9 9.2 7.9 1 23 292 315 292 315 0.97

3 10 0.0021 0.17 13.1 0.9 1 23 346 369 346 369 0.97

4 10 0.03 2.3 9.5 0.1 2 23 378 400 377 400 0.94

5 10 0.19 15 7.0 0.1 2 20 411 429 411 431 0.94

6 10 0.00013 0.0098 17.0 0.4 3 23 441 461 441 461 0.99

7 10 5.2e-05 0.0041 18.2 4.0 1 23 516 538 516 538 0.98

8 10 8.1e-05 0.0063 17.6 0.7 1 23 544 566 544 566 0.98

9 10 4.1e-06 0.00032 21.7 2.4 1 23 572 594 572 594 0.98

10 10 0.0018 0.14 13.4 4.2 1 23 600 623 600 623 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.048	3.8	8.9	0.4	1	23	263	285	263	285	0.98
2	10	0.038	2.9	9.2	7.9	1	23	292	315	292	315	0.97
3	10	0.0021	0.17	13.1	0.9	1	23	346	369	346	369	0.97
4	10	0.03	2.3	9.5	0.1	2	23	378	400	377	400	0.94
5	10	0.19	15	7.0	0.1	2	20	411	429	411	431	0.94
6	10	0.00013	0.0098	17.0	0.4	3	23	441	461	441	461	0.99
7	10	5.2e-05	0.0041	18.2	4.0	1	23	516	538	516	538	0.98
8	10	8.1e-05	0.0063	17.6	0.7	1	23	544	566	544	566	0.98
9	10	4.1e-06	0.00032	21.7	2.4	1	23	572	594	572	594	0.98
10	10	0.0018	0.14	13.4	4.2	1	23	600	623	600	623	0.96

Sequence Information

Coding Sequence: ATGGATGAGTTAAAATATTGCAGAGTATGTCTTGTGACTGATGTGAAGATGTTTAGCTTGGAAACTACGTCGAGCGATTCCATCGGTGTTGTTTACTCACATTTGGCGCAGATTCCGATATTTGATAGGAATCAGCATGTGTGTTTTGAATGTGCCAGTCTCCTCCACAAGTATCAAGAGTTCAAGTCAAAATCTCTCAGAGCTCACAACATTATATCTAGACTCAAACTTGGTTCATCACAGATAACAAGAAAAATCCTCAAAAAAGTAgataggaaaataaataaattggaatcCAACTTAATATTATCTCCGGTAGCTATCCTTTATGAAGAACCTGCAAGTAACACagaaacagaaatacatctacaagacaaagaaaataaacaatttgaaattaatgttaaaatagaAACAGTCAATAACAGTCAAGAAATAGAAAAGACATATGATTACAATGAATCATTTAATGAAGATTACATTGACTTTACAGAAGACTCAGTCCCTGAGAAGGTTACACAACCAAAACATAAAAGTAAACCAAATAaggaaacaaaaagtaaaaaaagaaaagtaaaaactgttattaAGAGCGAGGATGATTTCAGTGATGATGAACCTTTATCAAAAAGTGCTACGAGAGTAAACACAAagcctattaaaaaaaagaatggcCTAAACATTAGTTACTTTGATGAATATGCTACTGTTGTGTTTCTGACCCCTGAAGATGCCAGAAAAGAGGTGCTCTTGAGAAAAGAGTCCAGTAACTATAAAAAGTCACCATTCAAGTGTGATTTGTGTTATAGAGGATTTGAAGCAATAGCAGCATTTGAGaatcatacaaaaaaacatagCATTGAGAACGGGAACTATGAATGTGATGCCTGCCATCTCAGGTTTCCTCAACAAGTACACTTGTGTAAACATAGACTTTCATGTCATAAGAGAAAGTTTAGCTGTAAATTATGCTCATACATTTGTTATTGCACTTACCAAGCGAAAACCCATGTTAGTCTACACAAAGGAAAGAAATATCCATGTAAACACTGTGGAGATATATTCAGcATGCCAAACAGCTTACTAATGCATAAACGTATCAAGCATTTGAAGGAGTTTGTACGGGAAAGTGTTTGTGAGCTTTGTGGAAGTACCTTCGGCACGCCCAGGGGACTGTTCTTACATAACATGAAAGTGCACAGGCAGgatAAAAACGACAAGCTCGGCCCTGAGTGTGAAGACTGCGAGGCGCACTTCACATCAGAACTAGCCTGGAAGCGACACTTAGTGCTTTCTACTAAACATAAAGTCAGTAACGGTTGCAAATTCTGCGGAGACACATTCTCGAACGAGGACGATCTTAAGGTTCACTTGAGAGTGCACTCTCGGAAGCCAATGAACAGATGCAATAATGTAAAACTACCCGCCGCCTGTGCTATTTGCGCCAAATGGTTAGTTAACCGCGTGGAGTACAAGAAACACGTGACATCAGAGCACCCTCACAGCGACGAGGCGAAGAAGTTCCACGCAGAAGACCAGACGCCCTTCGTTTGCGAAGTTTGTGGTCAGATGTTTAAGCAACAGTGCTTCCTAACATACCACCAACGGAAGCACACGGGCGAGCGTCCCTACAAGTGCCACGAATGTGACAAAACGTTCCAACTGGCCGGGGCGCTGTCTATACACCGCAGTATACACAATCGGAAGAGGACACATAAGTGTGAGATGTGCGCCCGTGTGTTTACATTCAAGAGTGCCCTTAACAAGCATATGaagGTCCACCTCGGCATCCGTCCCCACAAATGTGCGATCTGCGACAAAGGCTTCATACACATGTGCGACTTAAAGCTGCACATCAAATACGTGCACGACAAGATACCGTGGcctaagaaaaaaaacaagagaACTCTTGTTGATGATACTCCGTATTTAGAATACCACTGA
Protein Sequence: MDELKYCRVCLVTDVKMFSLETTSSDSIGVVYSHLAQIPIFDRNQHVCFECASLLHKYQEFKSKSLRAHNIISRLKLGSSQITRKILKKVDRKINKLESNLILSPVAILYEEPASNTETEIHLQDKENKQFEINVKIETVNNSQEIEKTYDYNESFNEDYIDFTEDSVPEKVTQPKHKSKPNKETKSKKRKVKTVIKSEDDFSDDEPLSKSATRVNTKPIKKKNGLNISYFDEYATVVFLTPEDARKEVLLRKESSNYKKSPFKCDLCYRGFEAIAAFENHTKKHSIENGNYECDACHLRFPQQVHLCKHRLSCHKRKFSCKLCSYICYCTYQAKTHVSLHKGKKYPCKHCGDIFSMPNSLLMHKRIKHLKEFVRESVCELCGSTFGTPRGLFLHNMKVHRQDKNDKLGPECEDCEAHFTSELAWKRHLVLSTKHKVSNGCKFCGDTFSNEDDLKVHLRVHSRKPMNRCNNVKLPAACAICAKWLVNRVEYKKHVTSEHPHSDEAKKFHAEDQTPFVCEVCGQMFKQQCFLTYHQRKHTGERPYKCHECDKTFQLAGALSIHRSIHNRKRTHKCEMCARVFTFKSALNKHMKVHLGIRPHKCAICDKGFIHMCDLKLHIKYVHDKIPWPKKKNKRTLVDDTPYLEYH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01027699;
90% Identity: iTF_00238121;
80% Identity: -