Basic Information

Insect: Lithophane leautieri
Gene Symbol: ZNF280A
Assembly: GCA_949152455.1
Location: OX424487.1:4614103-4626373[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0077 0.6 11.4 2.1 3 23 239 260 238 260 0.94

2 10 0.015 1.2 10.4 0.3 2 23 286 308 285 308 0.95

3 10 0.017 1.3 10.3 0.5 2 23 332 353 331 353 0.95

4 10 2.2e-06 0.00017 22.5 1.5 1 23 357 379 357 379 0.98

5 10 0.13 9.8 7.6 1.3 1 13 384 396 384 398 0.91

6 10 0.0022 0.17 13.1 1.6 2 23 416 438 415 438 0.93

7 10 4.4e-06 0.00035 21.6 1.7 1 23 445 468 445 468 0.98

8 10 0.016 1.2 10.4 0.5 1 23 474 496 474 496 0.96

9 10 3e-06 0.00023 22.1 0.9 1 23 502 524 502 524 0.99

10 10 0.00036 0.028 15.5 1.3 1 23 530 553 530 553 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0077	0.6	11.4	2.1	3	23	239	260	238	260	0.94
2	10	0.015	1.2	10.4	0.3	2	23	286	308	285	308	0.95
3	10	0.017	1.3	10.3	0.5	2	23	332	353	331	353	0.95
4	10	2.2e-06	0.00017	22.5	1.5	1	23	357	379	357	379	0.98
5	10	0.13	9.8	7.6	1.3	1	13	384	396	384	398	0.91
6	10	0.0022	0.17	13.1	1.6	2	23	416	438	415	438	0.93
7	10	4.4e-06	0.00035	21.6	1.7	1	23	445	468	445	468	0.98
8	10	0.016	1.2	10.4	0.5	1	23	474	496	474	496	0.96
9	10	3e-06	0.00023	22.1	0.9	1	23	502	524	502	524	0.99
10	10	0.00036	0.028	15.5	1.3	1	23	530	553	530	553	0.97

Sequence Information

Coding Sequence: ATGTCGCACGGCATCGTTTGCCGCTGCTGCCTCTTGCGAGCTCCTGATAAAGACCTGACGACTCAATATTCAATACTGGGCAAGTCAGAAGTTTACGCCGATATGTTGAAAGATTGCTTCGAAATTCAGATATCTCTGGACCCTAATAACAGCGATGGCGGTATTTGTGAAGTCTGTATCACAAGGCTACGGGATGCATGCAACTTCAAAGAACAAGTACAGCAGTGTCAGAAGGAGTTCATGTCTAAACTTAACACTTACAATGTTAAAGATGAATCGGGTCCAAAGGTGAAGGAAGAATTTCTAGATTTGGACGACGACAATGGCATATATTTTCTAGAATTAAAAGAAGAAATGTCAGATGATTTCGACGATTTCAAAGACGAGGATGATAACAAGAAACTCGCTGAAATGCTTGGGTTTAATGACGTCACGATCAAGAAGAGATCCGAAAAACGTCGGAGTAAGAAACGGCTGCTTCTTGAAAATAGCAGGAAAGaattgaAATCTAAACGCCGCAGCATGAAGATTTCCCTTGATGATCTGACCCAACAACGAGTGATGATGAACAAGATCCTGAAGCCTGTCAAGaTATCCTCGGACACCGGCAAGCGTCTGATCAGCGATGCTTCTAAAAACAGATTTAATGTGGACATACTGCTCAAATACTCCAACTGTACGCCATTCGCGAACAAGACTATTGCAGGGATCCTCTGCGCTTACTGCAAGACAACGTACCGAGACCTACCTCACCTGCGCACACACATACACGAAGAACATGCCAACGACAATCTCATAGAAACTAAACGAATGGACAAGAACAATCTTTCCATCAAAATGGACATTACAGACTTACGGTGCAATATATGTAATAATAGTGCAGACACcataaccaatttaaaaaatcatttgtcTATGGAACATGATATCAAGTTCTATCCAGATGTAAATGATTACGTCCTGGAGTTCAAGCTAACTGACGGTGAAATTTTAAACTGTGCGCTGTGCAACTCAACTTTTGAAACGTTTAAAATGTTACTGCAACACATGAATGGACATTACAGAAACTACATTTGTGAAATATGTGATTTAGGCTTCATAAACCAACATAAGTTAAGAAATCATCAACGCACTCATGAAGTTGGGAATTTCAACTGTTCATTCTGTGATAAAATGTTCACTACTCGAGTTAGGAAGTTGTGCCATGAGAAGTATACTCATAACCCCAGTGCTAGATACACCACTAGTTGCCCACACTGCGAGGAATCGTTTACTAGCTACTATAGAAGAAACCGTCACATGGCGTTAGAACACAACATTTCTGCGGCaacatacaaatgtaacatctgtgacaaatattttattcttaaaTCTAAATTGACGTCTCACATAAAAAAAGTACACTTAATGGAACGAAACCACATCTGCCTGGAATGTGGACAGGGCTTTTTCATAAAGCAGTCGCTAGACGAACATATGATAAAACACAACGGTGAAAGGGTCTTCAAATGTACCGTCTGTGCTAAGGCATATGCTAGGAAAAAGACGTTAAGAGAGCATATGAGGATACATAATAATGATCGGAGATTCAAGTGTGGGGTGTGTGCTTTAGCGTTTGTGCAAAAGTGTAGTTTAAAAAGTCATATGCTCTCAAACCATGGGGTTACTTTAGCGGAGTATGAGAATGGAAGAGAGAGAACACGGGTTTGTAGTCCCTAA
Protein Sequence: MSHGIVCRCCLLRAPDKDLTTQYSILGKSEVYADMLKDCFEIQISLDPNNSDGGICEVCITRLRDACNFKEQVQQCQKEFMSKLNTYNVKDESGPKVKEEFLDLDDDNGIYFLELKEEMSDDFDDFKDEDDNKKLAEMLGFNDVTIKKRSEKRRSKKRLLLENSRKELKSKRRSMKISLDDLTQQRVMMNKILKPVKISSDTGKRLISDASKNRFNVDILLKYSNCTPFANKTIAGILCAYCKTTYRDLPHLRTHIHEEHANDNLIETKRMDKNNLSIKMDITDLRCNICNNSADTITNLKNHLSMEHDIKFYPDVNDYVLEFKLTDGEILNCALCNSTFETFKMLLQHMNGHYRNYICEICDLGFINQHKLRNHQRTHEVGNFNCSFCDKMFTTRVRKLCHEKYTHNPSARYTTSCPHCEESFTSYYRRNRHMALEHNISAATYKCNICDKYFILKSKLTSHIKKVHLMERNHICLECGQGFFIKQSLDEHMIKHNGERVFKCTVCAKAYARKKTLREHMRIHNNDRRFKCGVCALAFVQKCSLKSHMLSNHGVTLAEYENGRERTRVCSP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00449560;
90% Identity: iTF_00238089;
80% Identity: -