Basic Information

Insect: Lissagria laeviuscula
Gene Symbol: Zfhx4
Assembly: GCA_030264695.1
Location: JARJDU010001750.1:1-9294[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0002 0.022 15.4 0.2 1 23 24 47 24 47 0.96

2 14 3.8 4.1e+02 2.0 2.5 2 21 144 163 144 167 0.87

3 14 0.064 7 7.5 1.2 1 23 179 204 179 204 0.90

4 14 0.0026 0.28 11.9 1.6 1 23 222 244 222 244 0.97

5 14 0.00056 0.061 14.0 0.7 2 23 251 273 250 273 0.94

6 14 0.00072 0.078 13.7 3.2 1 23 375 399 375 399 0.92

7 14 0.0044 0.48 11.2 0.6 1 22 419 440 419 443 0.89

8 14 0.00088 0.096 13.4 0.2 1 23 497 521 497 521 0.93

9 14 0.0011 0.12 13.1 0.1 3 21 595 613 595 614 0.96

10 14 0.18 19 6.2 2.3 2 19 722 739 721 744 0.90

11 14 9.4e-05 0.01 16.5 2.5 1 23 1312 1334 1312 1334 0.99

12 14 0.0014 0.15 12.8 0.6 1 23 1422 1444 1422 1444 0.98

13 14 0.0051 0.56 11.0 0.4 2 23 1596 1618 1595 1618 0.96

14 14 0.047 5.2 8.0 2.7 3 23 1880 1902 1878 1902 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0002	0.022	15.4	0.2	1	23	24	47	24	47	0.96
2	14	3.8	4.1e+02	2.0	2.5	2	21	144	163	144	167	0.87
3	14	0.064	7	7.5	1.2	1	23	179	204	179	204	0.90
4	14	0.0026	0.28	11.9	1.6	1	23	222	244	222	244	0.97
5	14	0.00056	0.061	14.0	0.7	2	23	251	273	250	273	0.94
6	14	0.00072	0.078	13.7	3.2	1	23	375	399	375	399	0.92
7	14	0.0044	0.48	11.2	0.6	1	22	419	440	419	443	0.89
8	14	0.00088	0.096	13.4	0.2	1	23	497	521	497	521	0.93
9	14	0.0011	0.12	13.1	0.1	3	21	595	613	595	614	0.96
10	14	0.18	19	6.2	2.3	2	19	722	739	721	744	0.90
11	14	9.4e-05	0.01	16.5	2.5	1	23	1312	1334	1312	1334	0.99
12	14	0.0014	0.15	12.8	0.6	1	23	1422	1444	1422	1444	0.98
13	14	0.0051	0.56	11.0	0.4	2	23	1596	1618	1595	1618	0.96
14	14	0.047	5.2	8.0	2.7	3	23	1880	1902	1878	1902	0.89

Sequence Information

Coding Sequence: ATGCGAATGCAAGCCCATGTGTTAGCCCAACACGCGGGTGCATCGGCCTCCTCCAGTGAATCTCCTGGCTTCCAATGTCCACTCTGCCAAGACTCATTTAAAGATCGAGCTAGTTTAGAGCGGCACGTCATGCAGATCCATAGCGTAAACAGCGAGGGCTTGCAGCGTTTGCTAATGCTAGTTGATCAAAGCCATTGGCTCAACGCTGCTTCGCGTACACCGACACCAAATAACAATCATGCAGCAAGCGCACCGCCAACGCCGCCGACGACGGCAACGACAGCGGCTAGTCAACTAGTCTCGCCGACTTCAGCGTCTTCCAAAGACTCGAAGGAAAAGGGTGACGCCACCCCTAACCATAATGCAGATCTCGACGCCGGGTTACTCTCACCTCACAGCGATGATGCCGCTGATCTTGGCGAATGCGAGAGATGCACCACGTGTATGAAAAGCTTCCGCAATATCGACGAGCTGTGCTTCCATCAAAACGAGACCGGTCACTTGGAGATTAAACAAACACCAAGTGGTCCAGGGTATGCGTGCTGGAAGAAAGGATGTAATCAATTCTTTCCTACTGCGCACACTCtccaaatgcattttaaagaGGTGCATGCAAAGAACTCCGTTACACAGATGTCCGTCAGCGAGAAGCACGTATACAAATATCGGTGCAATCAATGCTCATTGGCTTTCAAAACTTTGGAGAAACTTCAGCTGCATTCGCAATACCATCTGATCAGGGATGCGACAAAATGCGTGCTATGCGGGCGCAGTTTTCGCTCGCTGGTGGCGCTCCATAAGCATGTCGAGAGCGTGCATTCCGAACTGACCGACGATGAATTGCTCGCGTACAAACAGAGCTTAATGAATAATCCATTGTTGTTAGCAGGGTTACAAGGTCAAGTCCTAGACAGCTCGACGAACGACATCTTGCGTAAAGAGTCCTTGCGCAATAACGAAGAGGTTGATGGATGCGACGATAGTGCCGAACACGACGACAGTAATATTAATGACGGCGACAATTCCGATGATAGCATCGTGTACAAAGATCAGCAGTTCCTAGAGGACTACCTCAACAGTCAGGCCATGGCCGAGGATAGTTATAATGATCCTAACCGGAAGTACAAGTGTCACCGTTGTAAGGTGGCATTCACACGGCAGAATTACCTCACCGCGCATAACAAGACTCTATTGCATCGCAAAGGCGAGAAACTGAGCTACCCCATGGAGAAGTATCTCGACCCAAATCGACCGTATAAGTGCGATGTGTGTAAGGAGAGCTTCACCCAGAAGAATATCCTCTTGGTGCATTACAACTCCGTGAGTCATTTGCATAAGTTAAAGCGTGCAATGCAAGAACAACAGcagaacaataacaataatccgCCGGTGTCACCAGTTTCGGGGCAGCAAGCTCAACCGGCTCAACCCACGACACCGCTGACACCCAAAAGCACTTCGAGCACCGAAGAAGATGACAAGAAGCGTTACCGTTGTAATATTTGTAAGGTAGCGTATACGCAAGGCTCCACGCTTGACATTCACATGCGTAGCGTATTGCATCAGACGAGAGCCAGCAAGCTCCAGGACCTGGCGCTCGCCGGGCAGATAGACCTCTCGAAGCCGCTCATTGAGCAACCAGAATCGCCAAAACGCGGCAGTCCGACGCCGAGCGGTGTAGTAGGGGAGAAGACGAGCGCCTCACCAACCACCACCCCGCCGTCGCCGAACCCCTCAGGTAATACGGCGAGCGGCGCAGGTAGCCAAGGGCTGATGGCGGGCTGTCCCAAGTGCGGTGCGCTCTTCAGTTCGTCCGATCAGTTGAACGCGCACCAGCAGCTGTACTGCATGTTCGCCGCTCCGAACATGGCCATCTTCCAGCAAGCGCAAGAGCCGGGCGCAGCCAAAAGTCCACCGCCGATGTCCGCCGAACAAGACGTCGCCGCCGGCCGCCTCGCGTTACCCAAACGCATCAATTCACAGATGCAGAAGCATCTCTTGGAGAGCTACGGCTTCGACGTGGTGATGCATTACAACGAGAGCCAACACCGCCAGCGGATGGCGAGCGCCGAAGACACAGACGCCGCCGCGCAGCCGCCGCCGACCAAGTCCGAGGAGAGCGCCGCCAGCAGCGAGAACAACTTACCCGAAGTAAGTACATCCACGTGCCAACATTGCAATAAGCCGTTCTCTAGTGTGTGGGTGTTAAAATCTCACTGTGAAGAAGTACATAAAGATTTAGTGCCGCTAGAATTCTTAGAAAAGTATGCTCAACAGTTCAAGAACGAATACGAAAAGAAAACGGTGGTGGTGACCGCGGCGACGTCGTCGACGTTAAACAGCGGCCCGCGCGTATCCACGCCGGCAGCCGATGAGAAGGAATCCGCCACAGCCGCTGCCGCCAACGCTGCGCCCGCCGACGAGTCGAAAGAGGCGCTGCACGCCAAGCTGAGCTTGCCGCCCCAGTCGGCGGCGGAAGCCGCGTCGCCGGCGCCCTCGACACCCGCCAGCAGCACCGATTCACTGCCCGCCAATATCCAGGCAATGATTGCGCAGACCATGGCGCAGAATCCGATGGCGTTTGCTCAGCAGATGACTGAGATGCAAGCAGCGCTGAATGTGATGCAGCTGCAACAGCAGCTTAACTTCAACCCCATGATGCAGATGATGGGCATGGGGCTGCCGCTCGGCTTGAATGCGCTCGCTGCCATGAATCTGCAGCCGCCGCTCGTCCCGCTCATgatgccgccgccgccgttcGACTCCATGCAACAGTTCAATCCGCAGGAACAGCAAGCCATGATGGCTAAACAGCAGCAACAGATGATGCAGCAACAGCAGGCGGCCGTGAGCGCAGCTGCAAACCAGAAACGCGCCCGCACGCGTATCACTGACGACCAGCTTAAGATTCTTCGAGCCCACTTCGACATCAACAATTCTCCTTCGGAGGAACAGATCCATGAGATGGCCTCACAATCAGGTCTACCACCAAAAGTCATCAAGCATTGGTTCCGCAACACGTTGTTCAAGGAACGCCAGAGAAATAAAGACAGTCCGTATAACTTCAACAACCCGCCATCGACCACCCTCAATTTGGAAGAATACGAAAAGACAGGGGAAACCAAAGTCATGCCGTTGAACAGCAGCGGGAGTAGTACCGATGAacctaaaaacaaagaatCTCCACCGCCGATGCCCTTTCAGCCGGCGGAGATCAAAACCGAGATGAAAGAAGAACCCAGTGAAGATCCAAAATTCGAGGATAAGGTGATCAATGATGGGGTAGATGAGAAACCGAATATCTTCAACCTTCCACCACATCTTCAACCACCTCAAAGTCCTGCCTCTTCTATGAGTAGCACAGATAATAATCATCACACCTCGACTTCAGCTCCTTCGACTCCAAACAATCTGACCTTAACTTCTATCATTGCTTCCCAATTAGGTGACAGTATAATTACCACGAGCACACCATCATCGCTCAATTTGACCGCATCCCCAATGCTGCCACCACCTAAACTCAATCAACAGAACTTCACACCGGGGAATTCTAGTATGCAAGGAATGCTCCCATTAACACCTAATCGCTGTCTCAGTCCGAATCGTGACTTCGCCACTATGAATTCCAACAGTAACAGTTCCACCGGAAGTAGTGGGAAACGTGCTAATCGTACGAGATTCACCGATTATCAGATCAAAGTTCTTCAAGAGTTCTTTGAGAATAATGCGTATCCCAAAGACGATGATCTCGAATACTTATCGAAATTGCTGAGTCTTAGTCCGCGAGTAATTGTAGTATGGTTTCAAAATGCAAGACAGAAAGCGCGCAAAGTATACGAAAACCAACCGGCGACGGAACCTTCGCCTGGAATTGCCGAGCAACAGCCCACTGAAGCAGGCGCTAATCGATTTCAACGAACTCCAGGTCTGAACTACCAATGCAAGAAGTGCCTGTTGGTATTCCAAAGATACTACGAGTTGATACGTCATCAAAAGACGCACTGCTtcaaagaagaagatgctAAGCGCTCGGCACAAGCGCAAGCCGCCGCCGCACAGATTGCAGCTGTTTTAAGTTCCGAAGATTCCAATTCGAGTACCACCATCGAACAGAACAATGCTCAGCAACCACCAAGTcaacaaaccatgcagccagcgcaTAGTCCGGCACAACCACAACCTCCAACGACACCCACACCTACTGGGAATACTCGCCCGCCGTCCCCAGCGCAATCCCCAGTCGATTCCTCCAAAGACGGCACCTTCCAATGTGACAAGTGCAATCTCGTGTTCCAACGGTTTGATCTCTGGCGTGAGCATCAATTGGTACACATCATGAATCCTACATTATTCCCGTCATATCCACCTGATTCCCCATTCGGGATTCTTCAGCAACATGCACAGTTACAACAACTGAATGCTGCGAATCTTGGAGTGGCTGATCTCACCATGAACAATGACAAGTCAGCGTCCCCGATACCATTACCTTTGATCAATATGTTGAACAATGTGACAGCGCAGAAACGCAAACTTGAGGAATACGATGGTGAGAGTGATGTTTCCGATCAACCGAAGGACAAACGCCTCAGAACTACTATCCTTCCTGAGCAACTGGACTACCTGTATCAGAAGTACCAAATCGAGAGTAATCCTTCCCGCAAGATGTTGGAGAACATCGCCAGAGAGGTAGGTCTAAAAAAGCGGGTGGTTCAAGTGTGGTTTCAGAACACACGCGCCCGAGAACGTAAAGGACAGTTTCGGGCACACGCACAAGTAATTAACAAGCGATGTCCCTTTTGTCCAGCACTCTTCAAAGTGAAGTCCGCCCTGGAATCACATCTCACCACCAAACATGCAGATCAATGTGCCCGAGGTGAGATCAATATCGACGCTCTCCCCGATGAAGAAAATAGTTTGGAATCATCGCCTAGTCTCAGTTCGGGAGGTGATAACAAGTTTAATGCGACACCAAACATGATGCCACCGCTGTTTCCTAATCTACACCCTGACATGGAGAATTCtatcaagaaatattatgaGGAGAGCATGAAGAGATACATCAGTGAATTGCAAGCACATGCTTCGAATGGTGACAAGAGTGAGATCAAAAGTGGCAAAGATGAAGGCACTGGAGAAATCCCTTTGGATCTATCCAAACCTGTAGATCTCTCGCGCCCAATGAAAGTAAACATGGACCATGAACGTAGTCTCTGTGATCCTGGTCCATTGACTGATCTCAGTGAACGTTCTTTGTGTGATGAACGCATGTCCGATTCGATGTCTGAAACTGCAGAATTCATGGATGACGAAAGCAATCCTACATCACCAGCTTCCAGTACCCAGAGCACCAATAATCCAGGAAGGCAAGGTGGCAGCACTACGAATTCCAATAAACGCTTCCGAACGCAGATGTCAGCTGTTCAAGTGAAAATCATGAAGTCTTTGTTTTCTGATTATAAGACACCGACAATGGCAGAATGTGAGATGTTAGGAAGAGAAATTGGTCTACCTAAGAGAGTCGTACAAGTGTGGTTTCAAAATGCACGCGCGAAAGAGAAGAAAGGAAAGATTGCCTTGCAAAAAGTCTTAGGAAATACTGAAACCAGTGAGAATACGACTCCTACATTACCTGACGATTGCAAATTCTGCGGGTTCAAATACTCTCATAAGTACTCAGTCCAGGACCATATCTTCACCAAAACTCACATTGCCAATGTGCGGACGCATCTCGAGAACGCCAGTTTGAAAGATTCTCGAGACAGAGACGGCTCTACCAATGAAAGCGGCGAGTTTACAGTGCCACCCATTCCTGGTGCTTCGGTCTCCGCTGATTCGACTACAAATCCACAACAAGCCCTGAACAACAACACacatttgcaattgttgcaaatGGCTGGGATGCAAATGGCCGCTGCAGTTAAAGCCGGAGATGGTGGTGACGATGCTAATCAAGAAGCCCTTTTCCAGCAGTTGTATGCACTAGGAAACAGTGGGAACTTCGGAGGACAGAACCAGTTCTTACACCATCCCATGTTCGGATCTAATG
Protein Sequence: MRMQAHVLAQHAGASASSSESPGFQCPLCQDSFKDRASLERHVMQIHSVNSEGLQRLLMLVDQSHWLNAASRTPTPNNNHAASAPPTPPTTATTAASQLVSPTSASSKDSKEKGDATPNHNADLDAGLLSPHSDDAADLGECERCTTCMKSFRNIDELCFHQNETGHLEIKQTPSGPGYACWKKGCNQFFPTAHTLQMHFKEVHAKNSVTQMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHLIRDATKCVLCGRSFRSLVALHKHVESVHSELTDDELLAYKQSLMNNPLLLAGLQGQVLDSSTNDILRKESLRNNEEVDGCDDSAEHDDSNINDGDNSDDSIVYKDQQFLEDYLNSQAMAEDSYNDPNRKYKCHRCKVAFTRQNYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQQNNNNNPPVSPVSGQQAQPAQPTTPLTPKSTSSTEEDDKKRYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLALAGQIDLSKPLIEQPESPKRGSPTPSGVVGEKTSASPTTTPPSPNPSGNTASGAGSQGLMAGCPKCGALFSSSDQLNAHQQLYCMFAAPNMAIFQQAQEPGAAKSPPPMSAEQDVAAGRLALPKRINSQMQKHLLESYGFDVVMHYNESQHRQRMASAEDTDAAAQPPPTKSEESAASSENNLPEVSTSTCQHCNKPFSSVWVLKSHCEEVHKDLVPLEFLEKYAQQFKNEYEKKTVVVTAATSSTLNSGPRVSTPAADEKESATAAAANAAPADESKEALHAKLSLPPQSAAEAASPAPSTPASSTDSLPANIQAMIAQTMAQNPMAFAQQMTEMQAALNVMQLQQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPFDSMQQFNPQEQQAMMAKQQQQMMQQQQAAVSAAANQKRARTRITDDQLKILRAHFDINNSPSEEQIHEMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGETKVMPLNSSGSSTDEPKNKESPPPMPFQPAEIKTEMKEEPSEDPKFEDKVINDGVDEKPNIFNLPPHLQPPQSPASSMSSTDNNHHTSTSAPSTPNNLTLTSIIASQLGDSIITTSTPSSLNLTASPMLPPPKLNQQNFTPGNSSMQGMLPLTPNRCLSPNRDFATMNSNSNSSTGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLSLSPRVIVVWFQNARQKARKVYENQPATEPSPGIAEQQPTEAGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTIEQNNAQQPPSQQTMQPAHSPAQPQPPTTPTPTGNTRPPSPAQSPVDSSKDGTFQCDKCNLVFQRFDLWREHQLVHIMNPTLFPSYPPDSPFGILQQHAQLQQLNAANLGVADLTMNNDKSASPIPLPLINMLNNVTAQKRKLEEYDGESDVSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCARGEINIDALPDEENSLESSPSLSSGGDNKFNATPNMMPPLFPNLHPDMENSIKKYYEESMKRYISELQAHASNGDKSEIKSGKDEGTGEIPLDLSKPVDLSRPMKVNMDHERSLCDPGPLTDLSERSLCDERMSDSMSETAEFMDDESNPTSPASSTQSTNNPGRQGGSTTNSNKRFRTQMSAVQVKIMKSLFSDYKTPTMAECEMLGREIGLPKRVVQVWFQNARAKEKKGKIALQKVLGNTETSENTTPTLPDDCKFCGFKYSHKYSVQDHIFTKTHIANVRTHLENASLKDSRDRDGSTNESGEFTVPPIPGASVSADSTTNPQQALNNNTHLQLLQMAGMQMAAAVKAGDGGDDANQEALFQQLYALGNSGNFGGQNQFLHHPMFGSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00903925;
90% Identity: iTF_00903925;
80% Identity: iTF_00903925;