Llae007311.2
Basic Information
- Insect
- Lissagria laeviuscula
- Gene Symbol
- topi
- Assembly
- GCA_030264695.1
- Location
- JARJDU010017677.1:8942-12129[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0011 0.11 13.2 3.5 2 21 134 153 133 154 0.94 2 13 3.3e-06 0.00036 21.0 1.0 1 23 179 201 179 201 0.98 3 13 0.0053 0.58 11.0 1.2 3 23 209 229 208 229 0.95 4 13 0.11 12 6.8 0.3 2 19 248 265 247 267 0.86 5 13 0.00024 0.027 15.2 2.0 2 23 333 354 332 354 0.96 6 13 0.22 24 5.9 0.1 1 20 360 379 360 381 0.91 7 13 0.0064 0.7 10.7 0.2 1 23 575 598 575 598 0.97 8 13 0.0018 0.19 12.5 0.2 1 23 602 624 602 624 0.97 9 13 8.2e-06 0.00089 19.8 5.4 1 23 630 652 630 652 0.98 10 13 0.017 1.8 9.4 0.2 1 23 658 683 658 683 0.96 11 13 0.15 17 6.4 3.3 1 23 689 711 689 711 0.86 12 13 1.9e-06 0.0002 21.8 0.4 1 23 717 739 717 739 0.98 13 13 2.9e-06 0.00031 21.2 0.9 1 23 745 768 745 768 0.98
Sequence Information
- Coding Sequence
- atgaTACGAAACGAACACCTTGGCTACATGAAACTACATCGATTATTCCCAGACGCAACAACTCTCTCAATGCAATTGAAGATCGATTGGAAGAATCAAAAGGTGGTCGGACAAAAAACCATCGCGCAATCCATCGTCTACAAATGCATCAACGATCAACAAGACAATGACTTCGAATTCAAGTTTAAACCATTCCATTCGAATGATTCATCCTCGATACGAGTGATCCGCTTAGGCGGCGTTGAGGATCTCAATCGGCATAATTTCCCGATCAATGTCGCCCCATTACTAAACGCAAATGGGAACAATGGCAAACAGCCATTCATCAATCAGAATGGCACGATCGCGAAGGCTCTGAAGAGGGGCGACACGAAGGTGCCGAATTTCCCTATGATGACAGTATGCCAAAATTGCGACACGCACTTCCCCACCAAATACCAATTTCAACGTCACCAATGTGAATTCAATGCCAACAAAGTCGTTCTGAAAGCAAATGTTGCCGAAAAAGATACCGAAGATGGTGTCCGCATGAAGTTCAGTTGTTCCACGTGTGGAAAACAATTTGTCAGTAAGAATAACTTAGATCGACATCTTATCAGTCACGATAAGGATAATGTCAACATATGTAAATACTGCCAGAAGCAGTTTGTCAGCGAGAATCGGCTTCGTATTCATAAAGAGAATCATTGTAAGAAAGCCGGGGGGTTGAATAAGTTTTATAGGAGCGATGTGAAAGTCTGGCGATGCAAGAAATGCTATCAAGTATTTTCATCGAACGAGTATGCGGGAAAGCATGCCAATGCATGTATGGATCTGATAACAGATCCTGAGGCGCTTAAGAATGCTAATGAAGGGATCAAAGTCGAATTGGTCGAGTTGAAGAATGAAGATGATCTCGATTGTAAGGACGATGAGAATAATCCGATGAGTGACGATGGTTCGCCATCTGCGAGTATCAATCCGTTCATTGATATGGTCTGTACAGAGTTACTGTTACATTGCGAATTCTGCAATCGGACCTATGCCAATAAGTATACTTTGTTATGGCATCAAGATACACATACGACTAGCGTTAATTACAATTGTGTTAATTGCAAGACTACGTTCGAGTCGTATATCAATGCTGCTAAGCATTGGCTGGCAGTATGCGCCAACGAGGCTAATCTCTTCTATCTACCAAAACTGATCTATTGCAAATGTTGCGACCGCACTTTTAAGTCCCACGAGATTCTCTATATGcacaaaataaagaagaaacacTACTGCCCTAAGAAACACACATCCACCGGAAATGAATACGTTCCTGATAAACATATATCAGAATCGAGTCTAATCAATGACGAAGAAGATAAAGATGACGATGCGGAAGTAGATCCCAAACCTGAGGATCAACAAActacaaaagaaaacattgGTCAAATAAAAGAAGACGAACGAAAGCACCGAGAAGAAACTGTTCAAAGTAAGGAACCTCTTATACTCCTAATGGAAGATGTCTGCGCTTCCAATCGAATAGAAAGACAACAAGAGCTCGATGAAAGTGACAATGTTAGTATAAAGTCTGAAAAGTTAAGTCATACTAGTCTCACACAATCTGAGTATACTCCCAGTATCCAGGAGAAGAATCctgagaagaaaaagaaacgtGGACGGAAACGAAAATCTTGTGCGCAGTATAATCGATCGAAGAAGATGACGGCTAATGTAGAATCTGGCTATAAGTATCAATGCGAACGATGTATTATTGTCTTCAATACAATATCTGATTTGGAAATGCATAGGAATAAGGATCATCCGGCGAATTACAAATGCGAGGAATGCGATCAGGTTGTACATAGTGCTAAGGCTTTGATGATCCATAGTCGTGCACATCAAAGCTTGAAGCCGTACGTTTGCGAAATTTGTAAACGGTGTTATTCGCAGACTTCACATTTATGGCAGCATATGAGATTCCATCAGGGAATTAAACCATTTGCATGCCCACATGAAGGATGCGAAGCTAGGTATACCATTCGTCCGGACTTGAAGGATCACATTAGAAAAGTGCACACTCGGGAGCGTCCATTTAAGTGCTCCGTGTGTAACAAATGCTTTCTGACAGGATCAGTTTACTACCAACATCGACTGATTCATACGAATGACAGGCGTTATGCTTGTGATGTTTGCAACAAGCGGTTTTTCCGTGCCGACGCATTAAATAATCACCGGCGCATCCATACTGACGAACGACCGTATCCTTGCAATGTTTGTGGACGAAATTTTAGACAGAAAGGTGATAGGAATAAACATGTGCGAACGCAGCATCCAGATTTCCAAATGTGA
- Protein Sequence
- MIRNEHLGYMKLHRLFPDATTLSMQLKIDWKNQKVVGQKTIAQSIVYKCINDQQDNDFEFKFKPFHSNDSSSIRVIRLGGVEDLNRHNFPINVAPLLNANGNNGKQPFINQNGTIAKALKRGDTKVPNFPMMTVCQNCDTHFPTKYQFQRHQCEFNANKVVLKANVAEKDTEDGVRMKFSCSTCGKQFVSKNNLDRHLISHDKDNVNICKYCQKQFVSENRLRIHKENHCKKAGGLNKFYRSDVKVWRCKKCYQVFSSNEYAGKHANACMDLITDPEALKNANEGIKVELVELKNEDDLDCKDDENNPMSDDGSPSASINPFIDMVCTELLLHCEFCNRTYANKYTLLWHQDTHTTSVNYNCVNCKTTFESYINAAKHWLAVCANEANLFYLPKLIYCKCCDRTFKSHEILYMHKIKKKHYCPKKHTSTGNEYVPDKHISESSLINDEEDKDDDAEVDPKPEDQQTTKENIGQIKEDERKHREETVQSKEPLILLMEDVCASNRIERQQELDESDNVSIKSEKLSHTSLTQSEYTPSIQEKNPEKKKKRGRKRKSCAQYNRSKKMTANVESGYKYQCERCIIVFNTISDLEMHRNKDHPANYKCEECDQVVHSAKALMIHSRAHQSLKPYVCEICKRCYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCNKCFLTGSVYYQHRLIHTNDRRYACDVCNKRFFRADALNNHRRIHTDERPYPCNVCGRNFRQKGDRNKHVRTQHPDFQM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -