Lnew011097.1
Basic Information
- Insect
- Liometoxenus newtonarum
- Gene Symbol
- topi
- Assembly
- GCA_030264535.1
- Location
- JARJEB010017676.1:6474-9153[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00066 0.052 14.4 2.4 2 21 136 155 135 156 0.94 2 12 1.5e-05 0.0012 19.5 1.6 1 23 181 203 181 203 0.97 3 12 0.0076 0.6 11.0 1.9 3 23 211 231 210 231 0.95 4 12 1.1 87 4.2 0.2 2 13 250 261 249 268 0.84 5 12 7e-05 0.0055 17.4 0.9 2 23 336 357 335 357 0.97 6 12 0.0099 0.77 10.7 0.2 1 23 610 633 610 633 0.98 7 12 0.0033 0.26 12.2 0.3 1 23 637 659 637 659 0.97 8 12 1.3e-05 0.001 19.7 5.4 1 23 665 687 665 687 0.98 9 12 0.026 2.1 9.3 0.2 1 23 693 718 693 718 0.96 10 12 0.13 10 7.1 2.9 1 23 724 746 724 746 0.86 11 12 1.7e-06 0.00013 22.5 0.5 1 23 752 774 752 774 0.98 12 12 1.4e-05 0.0011 19.6 2.5 1 23 780 803 780 803 0.98
Sequence Information
- Coding Sequence
- ATGAATCGCAATGAAAACATAGCGTAtttgaaaatacataaaatgttCGCCGACTCGACGATACAATCAACTCAATTGAAGATCGACTGTAAGACACAAAAGGTGATTGGTAAATTACCAATCGTCGCCGATCCGCAGCCAATCTACATGACATTTTTCAACTGCGACGATGATCAACTGTTCCAGTTCAATTCGAATTTTAACTTTAGTGATTCGTCGATTAGGGTGATCAAACTAGGCGGCGTTGAGGATCTAAATCCATTGAAATTCGCCACAGAAATAAGTACACTCTTTAATGATTGTGATATAAAAAATCCAGCACTCACTGCCGAAGCAAATTCATCAAACAATAGTATCCAAGCACCTAAAAGGGAGTCAAAGGTGCCTAATATTCCAATGATGATTCGATGCCAGAATTGCGATACGAATTTTCCAACGAAATACCAATTTCAACGACATcagtgtgaatttaacgccgACAAAGTGGTGCTTAAACCTAATGTCGACGCTAAAGATATTGAAAAGGGTGTtcgaatgaaatttaattgctCTACATGTGGAAAACAATTTGTTAGCAAGAACAATTTGGATAGGCACTTAACAAGTCACGATGAAGACAATGTTAATATTTGCGAATATTgcaataaacattttgttaGTGAGAATCGATTGAGGATACATAAAGAAAACCATTGTAAGAAGGCTGGGGACATTAGCAAATTCTACAGGAGTGATGTGTCTGTTTGGAGGTGCACTAAATGTTATCAGGTATTTTCAAATGAAGTCTTCGCATCTTCACATGCTGAAAATTGCACCGACATTATAACTGATCCAATTGCCATCAAAAATGCCAACGAGGATATATCCGAAGTAAGCGAGATGAAACAAGAAATGAATGTGGATTCTGTTTCTGGACACGCTGGAGGAGGTGAAGTAATATTGCCTatgaatttaacaaataattcacCAAAGTTCGTTGAAAAGATCCGAACTGAATTATTGCTACAATGTGAATTTTGCAATCGGACATACGCGAACAAAAAGTCATTGTTGTGGCATCAAGATACCCACACAACAAGCATCAATTACAATTGCGTCATGTGTTGTGAAACATTCGAATCATATGTCTTAGCTGCCAAGCATTGGCTAACAAAATGCGCGAACGAAGCAAATTTGTTCTATCTACCTAAACTGATCTATTGTAAATGCTGTGATCGCACATTTAAATCACATGAAATATTGTATATGcacaaaattaagaagaaGCATTACTCTGCGAAAAGACACATTTCGACTGGGAACGACGATGATACGGCACAATCGGAAACGAATGAAAACGGCCCTTGTGGTGAAGAACCAAAAACTTCCACTCATCAGTCAGCCAGTACGGGCGATCCGATTATTAAAGAAGTGGAGATGGAAATTGATGTTTGCAAAGAAAGTAAAATCGTAGAGAAGGGGCGCAAACGAGCAAAGAAACAAGATGCAAAATCAGCCAAATCAGAggataaaacagaaaataaagaaacgatTATAAAACTCATCGAAGACGTTTTGTGTTCCATCAAACACAAAATGAACAGCGACAACGAAGAACAGAAGAATTCTGATGAGGAGTGCGTAGAAGGACATGAAGAAGGGGAAGAAGACAAAGAAAATCCGTTATCGATAAAATCCGAGGTTGCAAGTCAGAGCAGTCTTATAATCGCTGAGGAAGTACCACCGGAAGAGAAAACAACCGGTAAGAAAAAGCGGGGACGTAAAAGGAAACCAGTTTCCCAATctaataaaaacaagaaagCGGTGGTAGTTGAACCTGGTTACAAATATCAGTGTGAACGCTGCATTAAAGTATTTGCCTCAATTATGGATCTGGAAGTACATCGCAATAAAGATCATCCAGCAAACTATAAATGCGAAGAATGCGATCAAGTCGTTCACAGCTCGAAAGCGCTAGTAATTCATAGCAGAGCACATCAAAGTTTGAAACCGTATGTTTGCGAAATTTGTAAAAGATGTTACTCGCAGACTTCACATTTGTGGCAGCATATGAGATTTCATCAAGGTATTAAGCCGTTTGCTTGTCCACATGAAGGATGTGAAGCTCGTTATACAATTCGTCCTGACCTTAAAGATCATATTAGAAAAGTTCATACAAGAGAACGTCCTTTCAAGTGTTCCGTCTGCGATAAATGTTTTTTGACTGGATCAGTTTATTATCAACATCGACTTATTCATACGAATGACAGAAGATATGCTTGTGATATTTGCAACAAGCGATTCTTCCGGGCAGATGCCCTTAATAATCATCGACGGATACACACTGATGAGCGTCCTTATCCATGCACTGTCTGTGGCCGTCATTTCCGGCAAAAAGGCGATCGGAATAAACACGTACGAACTCAACATCCTGATTGTCAAATATAA
- Protein Sequence
- MNRNENIAYLKIHKMFADSTIQSTQLKIDCKTQKVIGKLPIVADPQPIYMTFFNCDDDQLFQFNSNFNFSDSSIRVIKLGGVEDLNPLKFATEISTLFNDCDIKNPALTAEANSSNNSIQAPKRESKVPNIPMMIRCQNCDTNFPTKYQFQRHQCEFNADKVVLKPNVDAKDIEKGVRMKFNCSTCGKQFVSKNNLDRHLTSHDEDNVNICEYCNKHFVSENRLRIHKENHCKKAGDISKFYRSDVSVWRCTKCYQVFSNEVFASSHAENCTDIITDPIAIKNANEDISEVSEMKQEMNVDSVSGHAGGGEVILPMNLTNNSPKFVEKIRTELLLQCEFCNRTYANKKSLLWHQDTHTTSINYNCVMCCETFESYVLAAKHWLTKCANEANLFYLPKLIYCKCCDRTFKSHEILYMHKIKKKHYSAKRHISTGNDDDTAQSETNENGPCGEEPKTSTHQSASTGDPIIKEVEMEIDVCKESKIVEKGRKRAKKQDAKSAKSEDKTENKETIIKLIEDVLCSIKHKMNSDNEEQKNSDEECVEGHEEGEEDKENPLSIKSEVASQSSLIIAEEVPPEEKTTGKKKRGRKRKPVSQSNKNKKAVVVEPGYKYQCERCIKVFASIMDLEVHRNKDHPANYKCEECDQVVHSSKALVIHSRAHQSLKPYVCEICKRCYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCDKCFLTGSVYYQHRLIHTNDRRYACDICNKRFFRADALNNHRRIHTDERPYPCTVCGRHFRQKGDRNKHVRTQHPDCQI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -