Laer005591.1
Basic Information
- Insect
- Liodrosophila aerea
- Gene Symbol
- HINFP
- Assembly
- GCA_035045005.1
- Location
- JAWNNL010000648.1:1084725-1086229[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.22 16 6.3 0.4 3 23 21 42 19 42 0.92 2 9 0.017 1.2 9.8 0.1 3 23 123 145 121 145 0.89 3 9 0.073 5.4 7.8 3.6 2 23 164 187 163 187 0.96 4 9 0.0011 0.084 13.5 1.3 3 22 195 214 194 214 0.95 5 9 0.0015 0.11 13.1 0.8 1 23 223 245 223 245 0.96 6 9 1e-05 0.00075 19.9 1.8 1 23 249 272 249 272 0.97 7 9 3e-06 0.00022 21.6 1.5 1 23 278 301 278 301 0.97 8 9 0.017 1.2 9.8 0.6 1 23 306 331 306 331 0.93 9 9 0.56 41 5.0 4.0 1 23 338 361 338 361 0.95
Sequence Information
- Coding Sequence
- ATGATGACACAACATTCGAcggctaaaagaaaaaaatcctGTGAAATGGAGTTGGCGTGCTGCTGGGGGGATTGTCGAGAGATTTGCACTGGCGAATGGCAACTAAATAGCCACATAGCAGTCCATCTGGAGGAGATGCTGAAACAAAAGCCGCAGGAGGGAgagatatatatgtgtgtgtggaacaaTTGTGATTTTACGACCAAATGTAGTGAAGAGTTTGAGCGCCATAGCTATTACCATGGCTACTACCTGAATCTACTGCTGCATGGCAAGTGGGAATGCGAACAAAACCCGGAGATACCCGCCTGCTATGGGCCGCAACGAGATGGTGAAAAGCTGCCCGATCTCAAGCAGAATTTCCTGTGCGGCTGGACGGATTGCAATCGTTCGTTCGTGTCAATTGTCGAGTTTCAGGATCATATTGTGCAGCATGCTTCGTTCGagtatgagatacaaaagtcaCCCGATGACGAACGGCCCAAGACGCAGTGTAACTGGAATCTGTGCCACAAGCAGCTGGAGAACAAATACCGCCTCATCGAACACATTTGCACACACTCGAACAAGAAGCATGTGGCCTGCTTTCACTGTGGCGAACTATTTCGCACCAAGACCACGCTCTTTGATCATCTGCGTCGTCAGCCGGATAATAATACTCAGAAATTCCAATGTGGGCAGTGCTTCAAATTCTTTGCCACGGAGAAGCTGCTGCGAGGTCACGTCGTGAGGCACATCAACTGCTTCAAGTGCACCATGTGCGACATGTCCTGCAGCACGGCTGGCGCACTGacaacacacatacgctaTCGCCATCTGAAGGACAAGCCGTTCAAGTGCAGTGAATGCGACACACGCTGCGTTAGGAAGTCCGATTTGGAGAGGCACGTCCAGGTTGTACACGAGAAAACGGTTCATCAATGCGATCAGCCTGGCTGTCAGTACTCGGTGCGCACCTTTGCCCAAATGAGAAGGCATTTGCTGGAGGTACACGGCAACAATCCCATCTTCTATGCCTGCCACTGTTGTGAACGCTTTTTCAAGAGCGGCAAAGCATTGTCTGTGCATCTGATCAAGAAGCATGGATTGAGTTTGCCATCGGGGCACCAACGCTTCACCTACATACTGGACGATAATGGTTTCTATCGCCTGCAGACCACACGCCTCGAAAGCCTCGAGGTCACACAACAAATACTTGCGCAACATATCAAAACTGAGACTGAACAGAATACGCCAGTGGCGGGCAGCTGCTACGAGATTGTCAATCCCATTGGTGCGGACTATGAGCGTATACTTGTGTCCAATGATGCCAATGAGGCGCACTTTGTGGGCGAGGTGACCATATCATTGCCCAGCCTCATGGATAACGATATTTTGTGA
- Protein Sequence
- MMTQHSTAKRKKSCEMELACCWGDCREICTGEWQLNSHIAVHLEEMLKQKPQEGEIYMCVWNNCDFTTKCSEEFERHSYYHGYYLNLLLHGKWECEQNPEIPACYGPQRDGEKLPDLKQNFLCGWTDCNRSFVSIVEFQDHIVQHASFEYEIQKSPDDERPKTQCNWNLCHKQLENKYRLIEHICTHSNKKHVACFHCGELFRTKTTLFDHLRRQPDNNTQKFQCGQCFKFFATEKLLRGHVVRHINCFKCTMCDMSCSTAGALTTHIRYRHLKDKPFKCSECDTRCVRKSDLERHVQVVHEKTVHQCDQPGCQYSVRTFAQMRRHLLEVHGNNPIFYACHCCERFFKSGKALSVHLIKKHGLSLPSGHQRFTYILDDNGFYRLQTTRLESLEVTQQILAQHIKTETEQNTPVAGSCYEIVNPIGADYERILVSNDANEAHFVGEVTISLPSLMDNDIL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00832453;
- 90% Identity
- -
- 80% Identity
- -