Basic Information

Insect: Liodrosophila aerea
Gene Symbol: -
Assembly: GCA_035045005.1
Location: JAWNNL010000646.1:784635-788438[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00042 0.031 14.9 0.1 1 23 159 182 159 182 0.96

2 14 0.0015 0.11 13.2 2.9 2 23 231 253 227 253 0.89

3 14 0.0071 0.52 11.0 1.0 1 23 353 376 353 376 0.93

4 14 0.049 3.6 8.4 2.7 2 23 425 447 424 447 0.96

5 14 0.0072 0.53 11.0 1.2 1 23 511 534 511 534 0.92

6 14 7 5.1e+02 1.6 0.1 2 14 553 565 552 577 0.83

7 14 0.0038 0.28 11.9 5.5 2 23 585 607 585 607 0.96

8 14 0.0008 0.059 14.0 0.1 1 23 698 721 698 721 0.95

9 14 3.6e-05 0.0027 18.2 0.4 1 23 781 804 781 804 0.93

10 14 0.0012 0.087 13.5 2.2 2 23 854 876 853 876 0.97

11 14 0.0013 0.092 13.4 1.4 1 23 956 979 956 979 0.92

12 14 0.053 3.9 8.2 1.5 1 21 1031 1051 1031 1052 0.95

13 14 0.57 42 5.0 0.1 2 23 1081 1105 1080 1105 0.84

14 14 8.2 6.1e+02 1.4 1.7 1 13 1123 1137 1123 1147 0.60

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00042	0.031	14.9	0.1	1	23	159	182	159	182	0.96
2	14	0.0015	0.11	13.2	2.9	2	23	231	253	227	253	0.89
3	14	0.0071	0.52	11.0	1.0	1	23	353	376	353	376	0.93
4	14	0.049	3.6	8.4	2.7	2	23	425	447	424	447	0.96
5	14	0.0072	0.53	11.0	1.2	1	23	511	534	511	534	0.92
6	14	7	5.1e+02	1.6	0.1	2	14	553	565	552	577	0.83
7	14	0.0038	0.28	11.9	5.5	2	23	585	607	585	607	0.96
8	14	0.0008	0.059	14.0	0.1	1	23	698	721	698	721	0.95
9	14	3.6e-05	0.0027	18.2	0.4	1	23	781	804	781	804	0.93
10	14	0.0012	0.087	13.5	2.2	2	23	854	876	853	876	0.97
11	14	0.0013	0.092	13.4	1.4	1	23	956	979	956	979	0.92
12	14	0.053	3.9	8.2	1.5	1	21	1031	1051	1031	1052	0.95
13	14	0.57	42	5.0	0.1	2	23	1081	1105	1080	1105	0.84
14	14	8.2	6.1e+02	1.4	1.7	1	13	1123	1137	1123	1147	0.60

Sequence Information

Coding Sequence: ATGGAAGGTATGGATCTGTGGACGTCTATGTTTTCGGCCGACTtcgacgaggaggaggaggagggcgAAAACCACAATAATGGCGAGCTTATTGGCGATGAAGACGATGAGAATGGGGCGGATTTTGACGACCTCGAAGTCGAAGGCAGTACCAGCAGCaggaaaagaagaagacaaaaaGGACAAGAACCCGATGATGATGccatatttgattttgaacTGGAACCCATTGTTAGTATTGCTGAACAAGAACCCGATTCACATACGGATACAGAGCGAACAGCAAGAAGAACATCTCTTCCATTGGCGCCATCAATACCAGGTGGACCAGCAGTACGTCCCATGCACCGTCAATCGTTGCCAGGACCGTTGGGGCCAACGGGATTAGCAATGCCGCCCACTCGTCCAACGACATCGCAGATCAATGCCACCGATGAGCACGGTGTGCCCATTAACTATGAACTGGGTGTGATCTACATCTGTCCGGCTTGCGGAGCAGAGTACAGGCAGCAGGATATGTGGAAGCGTCACATGAACCAAATGCATCAATACAATACACGCAAGGGACTCAATTTTGTGGCCATCGACAAGCTGTACCATCGGTGTCTGGAGTGCAACAAGCGGATTGCGATGCACAGTCGAGAAAAtctgctaaagcacaagttcaCCCATTTGCCATATCGCTGCACCAAGTGCTACATCTGTAAGCGAGAGTACAAATACAGGCAGGACCTGATGGTGCATCTGCGCATGGTGCACTGCGACGAAGTGGTGGCCATGATGCGTGACAGTGATCCCAGTGCCGGTCGCAAGACTCGTGTTCGTGAGCCACGCACAGAGGCACAACAGATCACTGCATCCTCAGCCTATCCCATGCCGAAGCATGACTCTGACGATGACTTTGAGGTAAGAAACGAACCCATGGAAACAGAAACGTTGACTGCCGATGATGCCGGTGGGGACGATGATGCCAGTCGCAAGCGGCAGCGTTCCTCTAACCCTattgggaatgggaatggcaaTGGGCCCGCGGATATCTGTGAGGACTATATAAACTACACGTGTCCGGATTGTGGCACCGACTGCGACACCCATGCCCAGTGGAGCCAGCACATTGAGTTCGTGCACGACTATGTGAGTAGGCGTGGCCTCAATTTTCGCAGCGTCGACATGCAGATGCAGTGCCTCGAGTGCAAGCAGTTTGTGATCCCCAACACCATAAAGATGTTGCGTGCCCACAAGTTtagccacttgccacagccagagTGGATGCGCTGCAAACTCTGCTACAAGGGCTACACGGAGCACCATGAATTAGTCGCGCATCTGCTGAAGCAACACAATCTGGAGACGTTGATAGCCGATGCCATCGAAGATAATGGTGAAGAGCATCTGCACCAGGTAGCAGATGATAATGAGGATAATAGCATCGGCATTGGCTGTGACGATGAATCCTTGTCACAGTCTGAAGATGTGCCTCGCCGTGGTGGACGCATTGGCAGCGATGACATTTATGAACCGCACATTGACTATTTGTGTCCGCAATGCGGTCGCGAGTTCTTCGAGAAGAAACACTGGCGCAGTCATGTGGTCAAGGTGCACGGCATGAACGATCTGTCCAAGCTCAATTTCGAGGTGATCAACGATCGGCAGCTGAAGTGCACCGAGTGCGAAAAGATCATAACGAATGCGTACGGCATACAGAATGCCCAGCAGCATCGCATCACCCACTTGCCATACAAGGCGTATGCCCGCTGTTGCAAGTGCCACAAATCGTACACGGATCGCAAGGGATTGGTCAAGCATTTGGCCACCTATCATCGCGTTGGCTACGAGGCACGTAAATCAAGTGGAGCGAGTGCTGTCAAAACACAGGCGCAGCCACAGTCGCAGCGCAAACAGATTGTCACCGTGGCCAATGAAACGTATGAGATTATCTATTTGGATGAGGAGGAGCTGTCCAATAACGAGGAGAATGACTTTGGCGAGCAGATGCAGGCGGACGATGATGACTATGCCATAGCAACTACCAGTAGTGCCAAGTTGTCACCAGCTACAGCccatcccaatcccaatcaaAATGTCAATCGCTACAAGTGTGTGGACTGCGGCAGCCTGTTTGCCACACAGGCAGCGCTCAAGACGCACATCAGCGAGGAGCACGACTTCATGGATACCCAGTACAGTGCCAAAAAGTTTGATAATGCCGAAGCCACGGAGGAGGCAGCTAAGCCAGCAGTTAAGGATGCAGCAGGAGGCGGAGGAGCAGCCTCAAGTAGTTCCAATAAACCCACGCCCATCAATACTTCCGGTCTGTCGACCATCGAACAGAACTACATCTTCCTCTGCCCCTCGTGTGGCAAGTCGTACAAGACACAGTTCGAGTGGAGGCGCCACATCAATGAGGCGCACAACTTCGATAAGCGGCAGTCGTTGAACATGCGTCAGCTGGATAAGTACACCTATCAGTGCACTCAGTGCAAGGACGTGGTGTGCAATTCGAAGCTAAAGGGACTGCAGGACCACCATTTCCGGCATCTGCCCTACAGATTGTATCTCAAGTGCTTGGTCTGTGGCACGTGCTACAACCACAAGCCCAACATTGCGGCACATTTGCGTACGCGCCACAACATCTTCGAGCGGGAGCTGGTTAAGGCGCAGCACTCCAGTAACTCCAAGGAGCGGGATAAAGAGCGCGGGGAGAAGGAAACGCGTGTCATAtcctcatcgtcgtcatcgtcgccCACAAGCACTGGTCGCACGCTGAAACCACAGCCGGGTCTGCTGCCCACGCGACCCGCTGGACTCAACACGCTGGAGGATAGCATTTCATATCACAATGCCGTCGATCTGGACTTCATCACCTACTATTGCCCCAAGTGCAATAAGAACTTTGACTCGCACGCCTTCTGGCGCAAGCACATCGTCGAGGTGCACAACTATAATAGTCGCCAGGGCTTGAATTTCCGCCAAATCGATATACATCATTATCTGTGCCTCGAGTGCTACAAACGGGTGACGGTCACCCACACCAAGGGCGCCATTGGCCAGCTGCAGTCGCACAAGTTTCGCCATCTGCCCCATCGCTCCTTCAAGTGCTTGACGTGCAACGGGGAGTTTGTGCGCAAACAGATGTTCTTCAAGCACCTGAATCGCGACACCAATCGCTGCGATAACCAGCCACTTGGCAgccaggagcaggaggagcatGCAGTTGTTGATCCTGCAGCGTATACGCTGATGTGTCCACAGTGTGGCGACGATTTCACTACCAGCAGCAAGGCGCTCTGGCGGGAGCACATCAATATCCAGCATAGTCTCGGCAAGCGCGAGTCGCTGCACATGCGCCAGATCGGGGACGACCTCTATCGCTGCACGGACTGCCAAGAGCAGCTGCAGACGAAACACTTGcgtgtgctgcagcagcatcgcTTCCGACATCTGCCTTACGCTGCCTACATACGCTGCCAGCTGTGCGAGCAGCAACCGGACGGACTGGGTGCAGTGGCAGCCGGACTGCACAGCATgctggagctgcagcagcacatgcagcaacagcatcccGCCGAGAACGTTGAGCaaatgcagttgctgcagGAAGACGAGGAGGACAGTCGGCAGCAGCAATCGCAGGCAGCACAGGAAGAGAATGGTCCTTACATGCCGCTGCCACCGCATCTACTCGACGATGACGATATGGGGGATGTGGAGTTCGAAGATCAGTATCTGCTGGGATAA
Protein Sequence: MEGMDLWTSMFSADFDEEEEEGENHNNGELIGDEDDENGADFDDLEVEGSTSSRKRRRQKGQEPDDDAIFDFELEPIVSIAEQEPDSHTDTERTARRTSLPLAPSIPGGPAVRPMHRQSLPGPLGPTGLAMPPTRPTTSQINATDEHGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRKGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRDSDPSAGRKTRVREPRTEAQQITASSAYPMPKHDSDDDFEVRNEPMETETLTADDAGGDDDASRKRQRSSNPIGNGNGNGPADICEDYINYTCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKQFVIPNTIKMLRAHKFSHLPQPEWMRCKLCYKGYTEHHELVAHLLKQHNLETLIADAIEDNGEEHLHQVADDNEDNSIGIGCDDESLSQSEDVPRRGGRIGSDDIYEPHIDYLCPQCGREFFEKKHWRSHVVKVHGMNDLSKLNFEVINDRQLKCTECEKIITNAYGIQNAQQHRITHLPYKAYARCCKCHKSYTDRKGLVKHLATYHRVGYEARKSSGASAVKTQAQPQSQRKQIVTVANETYEIIYLDEEELSNNEENDFGEQMQADDDDYAIATTSSAKLSPATAHPNPNQNVNRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEATEEAAKPAVKDAAGGGGAASSSSNKPTPINTSGLSTIEQNYIFLCPSCGKSYKTQFEWRRHINEAHNFDKRQSLNMRQLDKYTYQCTQCKDVVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERELVKAQHSSNSKERDKERGEKETRVISSSSSSSPTSTGRTLKPQPGLLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEVHNYNSRQGLNFRQIDIHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNQPLGSQEQEEHAVVDPAAYTLMCPQCGDDFTTSSKALWREHINIQHSLGKRESLHMRQIGDDLYRCTDCQEQLQTKHLRVLQQHRFRHLPYAAYIRCQLCEQQPDGLGAVAAGLHSMLELQQHMQQQHPAENVEQMQLLQEDEEDSRQQQSQAAQEENGPYMPLPPHLLDDDDMGDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -