Basic Information

Insect: Liodrosophila aerea
Gene Symbol: Trerf1
Assembly: GCA_035045005.1
Location: JAWNNL010001109.1:1086745-1096608[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00014 0.01 16.4 0.2 2 23 339 360 338 360 0.97

2 6 4.3e-06 0.00031 21.1 1.3 1 23 366 388 366 388 0.98

3 6 0.00042 0.031 14.9 2.5 1 23 394 418 394 419 0.94

4 6 0.00071 0.052 14.1 0.8 2 23 677 698 676 698 0.97

5 6 0.0019 0.14 12.8 0.1 1 23 1782 1806 1782 1806 0.97

6 6 9.5e-05 0.007 16.9 0.8 1 23 1960 1982 1960 1982 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00014	0.01	16.4	0.2	2	23	339	360	338	360	0.97
2	6	4.3e-06	0.00031	21.1	1.3	1	23	366	388	366	388	0.98
3	6	0.00042	0.031	14.9	2.5	1	23	394	418	394	419	0.94
4	6	0.00071	0.052	14.1	0.8	2	23	677	698	676	698	0.97
5	6	0.0019	0.14	12.8	0.1	1	23	1782	1806	1782	1806	0.97
6	6	9.5e-05	0.007	16.9	0.8	1	23	1960	1982	1960	1982	0.98

Sequence Information

Coding Sequence: ATGTGCAGCGCTTCTGTGGGCACTGAGGGATCCGTGACACTGCAACTGAGAGATACAAATGCCTTGGAGACAGTCGACAgtacaacaagcacaacagccacaagtgcagcagtaacaacagcagtaggaacatcaacatcaacatcagcagcagcagctgcagcgacagcagcaacatgcaAGAATGCATTGACTATTGGTTATCCGGATCCGGACATGTTAGCAGATGTTCTGGGCACCATACAGACAGCCTCACTCAAGAacaaacacagcagcagcagcagtagtagtagcagcagccacagcagcagctgcaacagcaatatTAAgcgcagcagtaacaacaattgCCGAAACCGTAGCAACAGCACTGCACCAACAATACTGAACAGTACTCTGGCAGGAGCAACCAGCTCCAGCTCGAGCATACATCTGAGCAATCCCAATAAGATAACCATAACTCGACGTAGTGCCAGCAATAAGATCAGTGTGCAGACTGTGAGCACCTCGACGAACACAACGATTAGCAGCATTAACGGTAGCAAAACCAACTACATTAAGAACTGTCTAatacgcagcagcagctgcagcaacacgGCCACCAATGTCACCACATTGGCTCAGATtatgagcaacagcagcactaGCAGCGCTGCCAGTTTACTTAGTcagcacaacaataacagcaactgcagcaacagcagcaactttaGCAACGCCTCATCCGtcggcagcagcatcagcatcggcagcaacagcagcagcaacaccagcagcagcagtagcaacgacagcaacagcagcagtggtcATAGTCTCACTTTCAAGAGCAACGGTCGAAATGTTCCTGGCgtagccaccaccaccaccaccagcaccaccacaacagcagcatacaccagcaccaacagcaatacgaacaccacagcaacaggcaTAGGCCTTGTCACCGTCGACAATACACCTAGGAAGAGCCGACCCAAGTTATCATCGCCCACACGTCACGGACCACAGCAGTGTCAGATTTGTAGCAAGATCTTTGGAAATGCCTCGGCGCTGGCCAAGCACAAACTGACGCACAGCGACGAACGGAAATATATTTGTGCGCTCTGCTCGAAGGCATTCAAGCGTCAAGATCACTTAAACGGACACATGATGACGCATCGGAACAAGAAGCCTTACGAGTGTAAGGCGGATGGCTGTGGCAAATCGTATTGTGATGCACGCTCTCTGCGCCGTCATTCGGAAAACCACCATGGAGGCGTGGCAACGCCCACAAACAACTCACTCTCGCcgacggccatcagcagctgcagcggcggcagcagcagcagcaacagtgccAGCAGCGTGGGTGTAGCCAACAGTTCGCTAAGCCTATCGCCAGCAACGGCCAGCGGGGATGCCAGCTCACCGGATGGCGCCACCTGCATACGCACCTATATATCCACAGGCAGCTCGGTTGTGGATGCAGCCACTGGCATCGCACTGTCCGATGAGCAAATCAAGGCCATGAACTTACCGATCAAGACAGGTGTCACCCTGCTATCGCCCACCACATCGACATCCTCGAATGCATCGTCCACAGCATCCTCGTCGTGCTCGTCCACAAGTGGCAGCACTAGTGGCAACTCCATGACCATGACCAGTTCGCCCACCATCACGCTTAGCGATGGCGCCATGCTGGAGGGCGAGGGGCTCACGCGGGAGCAGCTCGATTTGATCAGCAAGATAATGCAGCAGACCAAGCAGACCAGCGCCCAGGTCACCGTCTCCTCACCCACCAGTGTCAGTTCCTACAAGATCAATACCGAAACTGCAGCACCTGTGCAGGCCAGGCCACGCACCTGGAATATGCAATTGCTCAACAATTCGCAAAATGTGACCGTAACTGTTGAGGATGGCACGGATCTGGTGGCCTCAGCTGCCAGCTCACCCGTCGATGTCAAGGAGGAGGAACTGAGCCAGCAAATTGTGGCCGCCATCAATCCCCACCTGCTGAACATTGTGAAGATCGACAAGCCGGTGGAGTGTAATCTGTGTCATCGCAAGTTCAAGAATATACCCGCACTCAATGGCCATATGCGTCTGCATGGCGGCTACTTCAAGAAGGATCCGGAAGCCAAGCGTAGCGAGAAGAAGGACTCCAGTGGGCCGCCATTGCAGACGGCCAGTATTGGTGTGAGGGCGCTGATTGAGGAGAAGATCATCAGCAAACGCAAGGATATTAACAAGGGCGCCTTTGTAGTGCCTGCTCCACCCGGTGCTAGTGGTGGTACTAACAGCGCTGGAACAGTTAGCATCAATGGGAATAGCAACgtgagcagcaacaacagcagcttgAGACGTTCCATTAGTGAACTGGAGAGTTTCCTCAATCCAAAGAGCAGTCTAAGCCAGGCCTtggcctgcagcagcagcagtagcaccaCCACAGCGGTGCTGCCAGCCGCAACCACCATAAAGAGCAGCAATGGCCTGAGCATACAGCAAATCGGTTTGCCCCAAAGCATTGAGATCTTCAGCGGTGCACAGCGGCAACCCAAAACACTGAGTCTGGGCAGTGGTGCCAACACCATAACCATAACCACCAACAATGTGCCTACCACAACCACAATGAGTGCGCTGACGGCACTTAAGGCCGGCAACAGTGTCCACAACACTGGCCACAGCAATCCCGATCCCAAGGACTCCACATTGATTGAGCTGCTCAAGCGTGGCACTCGCATCGCTGTCACCTCCAAGAAGCCGCAGCCAGGAGCCAATCTGCTGCTGAGCAATATGTCCATGGGCAGTGCAGAGCTGACGGCCATTGGCAACGGTGGACGTCAGATCATCACCAATAACAATCGCACTGTCATCATACCCTCGGATGTGCATGTGGTGTCCAGCAAGAGCAAGCTGATTGCCACTGGCGGCAACAGTAGTGGGAACGCAGCGAGTAGCATCTCTCTGCCGGATGGCACTCCGCTCTCACTGACCATTGCGCCCAGTCATCAGGAGAGCCTCGGTGTTGGGGGAGGggcaagcagcagcattacTGATGACTCTGGCGGTGTCTATACGGTGACATACACCAGCGATGCGGATGCAACGGATCTCTTCGATGATGCCGAAGTGTACAATGTCACTGACACGGAAATGCTGCTGCAGACCGTGGACACCATGGAGCTGCTgaatgatgatgaggatgaggcACACAAAAGCGAACATTCCGAGGACTTTGCACTGCTGAGCGAGCCCACACAGCTGATCAAATTGGAGCCAGAGTCCAGTGGGGTGTGCCAACAACAGACCACAACACCGCTGCCCACCTTCCAACAATTTCATTCCAAGGAGCTCATCATGCAGAATAGCTCACAAATCCAGGCCATTGCCAGCATGCGTGGCAGCAGCACTATGGGTGTGCTGGCATCGCCACTGCACTCCCCCCTGGCCTATCCCACACCGCCCTCGAGCCACGAGAATGTGGCACAATCATCGCCATTCATAGAGGATGCCGCAGCTCAGTTTGTGGATGCGAACCATACGTTCTTTGGGGACAAGACAGACTTCTCGCATGTCTACTTCAAGACGGACGATGGCGATGCCCTGCATGAGCTGAGTGAGAACGACAACGAGAAGATACTGAAGCTGAAAACAGTGCTGGAGGAGAGTAGCTTCGATCAGTCCATTAAGGTGGAGGATCTGTTGAATAATGGCGAAGACGATGCTGGTTGCGATCTGCGTGAGTTTGCCGAGACGAATCTATCATTTCTCGATGAGGATCAGGAGTTTCTAAATGATTCACGCAACGCCACCTCGCCGCTGTCCGAGTCCTTCTTCACCAGCGGCATTGGCTCCGCTGAGGATGTGAAACAGGTGCTGCGTGAGGTGTTGCCCGAGGAGAacatgcagctgcagctgagcagCGAACAGCAGGGTGAGAACATAATCGATCTTTACTATTTACCTGGTCTGGGATTGCAGTCGCAAATGATGCCCAACTCGGATGATCCGCTGCTGTCCTCCTCACCGCGTGAATTTggacagcagcgacagcaggtgttgcatgcaactgccacaactgTGCCAGCACCAATGGACCAGACTAGCCAAGTGCTCtatgagcaacagcagccggaacagcagcagcagcagcacccagtgccacagcagcaacaggagtcCCAACTGCTGCCACAACAGACTGTCATAGCAGCTGaagcaacacagcagcagcagcaacagcagcaacaaacggAGTACATGTTGCCCACGTACACTCAGGTGTCGTGTCAGGCGCAGTATGTGGACACCAGTCAGCATACCATGACCCTGCAGCCGCTGAACAGTCTGCTGCAGCCGTTGCTCTACggtaccaccaccaccagcaacaccaCCACGGTCAGCGATGGCACACTCctgggcagcagcagttctGTGCAGGGCACCATGCTGGATGGTAATACATTCTTCTCCTacggcgacagcagcagcattaccAGCTGCCAGAAGCCAGCACTGGCCACAGTCAACACTTCCATGGTTACGCCCAGTCCAAGTCCGAGCGTTGCCAATCTGCAGCCGTTGTCCAATCAAACGAATTCCATACTGAAGCGTCGTTTGCGTTCGAATGGAGCACAGGATGTGCACAAGCTTTCCAAATTCCATACACTGTCGCCGCATCGCTCCAAGCTGAGGAAACCGTCGCGCACACACTACACTCCAGCGCCCATACTGAATCCGGACCGCAAGGGCACCGGATTGTATTGTAATGTACGCAAACAGCTCGGCCAGGGCATATTCGATGTGTTCGATGATGATTTCGGTGACCCAGTGGGTCTGGTGGACTTCTCCGATGAGTCCAAGGTTAATCTTGGCTCCACGTATCAGGCACAGATACCAGCTTGGAAACCCATCGACGCTGCCTATGGCAAGGATTCAATAGGCGCCGACCTGATGTGGGATCCCAGTGTACAGGTCGATGAGAAGATACTCATGCGGTATATAGATCTCAGTAAGTCATCAGCCGTTCCCATGGGCAGTCACTCCGAGGAAGTCGCACTCCAAACGCTGCTCGAGGCCAAGGGCAATTCGGCAGCAGCCGTACTAACATTGCTGCAGACGCAGTCCAGCGCATTCCAAATGAAATGGACTGCCTATGAGCTGGAGCAGTTCCTGCGTGGCCTCGAGAAGCATGGCAAGGACTTTGGCAAAATTGCTAATGAGCTGCTCACCAAGACCTCCGGCGAGTGCGTGCAGATGTATTACTTTTGGAAGAAGCTGTGTGTGGACTACAAGGTGTCTCATCTGAAAATGGAGCCAGTTACACCTGTGACACCGACGGTGGAGCAGAAGCCCTACGTCTGCGAGATACCTGACTGCTCGGCGAGCTTCAGTTCGAAAGCGGCGCTGCACGGTCATGTACGCATACATGCTTATCACGGCAGAaatgccagcaacaataacaatcacaacagcaacaacaacaacagtaacaataacaacagcaacaataatcacaacaacaacaatcagcatGCCACGGCAGTTagtgccaacagcaacagcaacaacaacaatcacagttgcaacagcagcaacagcaacaacgcaTGCGCGCCCCCAACCAGCAACAATACCAATCATTGCATTAACGCAACAattgccactgcaactgcagccacaacaaccaTAATAAatctcaacaacaacaataacaataacagcaacaacatgggTCACCCCTTGGCCCAAAATGCCATATTgctagcaacagttgccgcaacgacaacaacagcaacatcagcagcattgaaggacaacagcaatagccagagtcagagccagagccagagcaacaTCAGCAATACCAATCTTGTCAAGGATACCGAATTTCCCTGCAAGGTGTGCGGCAAAGTGTTCAATAAGGTGAAGAGTCGGAGTGCTCACATGAAGACGCATCGAGTGCAGGATGCAGATCaaacagcaaatgccaaacacCAGCCAAACGctcactcgactgcagcatcagtcacagccacagcctcagtcgctgccgcagtcgccgccgcagccgcagccgcagcctcTCTAGCTACGTCATCGTAG
Protein Sequence: MCSASVGTEGSVTLQLRDTNALETVDSTTSTTATSAAVTTAVGTSTSTSAAAAAATAATCKNALTIGYPDPDMLADVLGTIQTASLKNKHSSSSSSSSSSHSSSCNSNIKRSSNNNCRNRSNSTAPTILNSTLAGATSSSSSIHLSNPNKITITRRSASNKISVQTVSTSTNTTISSINGSKTNYIKNCLIRSSSCSNTATNVTTLAQIMSNSSTSSAASLLSQHNNNSNCSNSSNFSNASSVGSSISIGSNSSSNTSSSSSNDSNSSSGHSLTFKSNGRNVPGVATTTTTSTTTTAAYTSTNSNTNTTATGIGLVTVDNTPRKSRPKLSSPTRHGPQQCQICSKIFGNASALAKHKLTHSDERKYICALCSKAFKRQDHLNGHMMTHRNKKPYECKADGCGKSYCDARSLRRHSENHHGGVATPTNNSLSPTAISSCSGGSSSSNSASSVGVANSSLSLSPATASGDASSPDGATCIRTYISTGSSVVDAATGIALSDEQIKAMNLPIKTGVTLLSPTTSTSSNASSTASSSCSSTSGSTSGNSMTMTSSPTITLSDGAMLEGEGLTREQLDLISKIMQQTKQTSAQVTVSSPTSVSSYKINTETAAPVQARPRTWNMQLLNNSQNVTVTVEDGTDLVASAASSPVDVKEEELSQQIVAAINPHLLNIVKIDKPVECNLCHRKFKNIPALNGHMRLHGGYFKKDPEAKRSEKKDSSGPPLQTASIGVRALIEEKIISKRKDINKGAFVVPAPPGASGGTNSAGTVSINGNSNVSSNNSSLRRSISELESFLNPKSSLSQALACSSSSSTTTAVLPAATTIKSSNGLSIQQIGLPQSIEIFSGAQRQPKTLSLGSGANTITITTNNVPTTTTMSALTALKAGNSVHNTGHSNPDPKDSTLIELLKRGTRIAVTSKKPQPGANLLLSNMSMGSAELTAIGNGGRQIITNNNRTVIIPSDVHVVSSKSKLIATGGNSSGNAASSISLPDGTPLSLTIAPSHQESLGVGGGASSSITDDSGGVYTVTYTSDADATDLFDDAEVYNVTDTEMLLQTVDTMELLNDDEDEAHKSEHSEDFALLSEPTQLIKLEPESSGVCQQQTTTPLPTFQQFHSKELIMQNSSQIQAIASMRGSSTMGVLASPLHSPLAYPTPPSSHENVAQSSPFIEDAAAQFVDANHTFFGDKTDFSHVYFKTDDGDALHELSENDNEKILKLKTVLEESSFDQSIKVEDLLNNGEDDAGCDLREFAETNLSFLDEDQEFLNDSRNATSPLSESFFTSGIGSAEDVKQVLREVLPEENMQLQLSSEQQGENIIDLYYLPGLGLQSQMMPNSDDPLLSSSPREFGQQRQQVLHATATTVPAPMDQTSQVLYEQQQPEQQQQQHPVPQQQQESQLLPQQTVIAAEATQQQQQQQQQTEYMLPTYTQVSCQAQYVDTSQHTMTLQPLNSLLQPLLYGTTTTSNTTTVSDGTLLGSSSSVQGTMLDGNTFFSYGDSSSITSCQKPALATVNTSMVTPSPSPSVANLQPLSNQTNSILKRRLRSNGAQDVHKLSKFHTLSPHRSKLRKPSRTHYTPAPILNPDRKGTGLYCNVRKQLGQGIFDVFDDDFGDPVGLVDFSDESKVNLGSTYQAQIPAWKPIDAAYGKDSIGADLMWDPSVQVDEKILMRYIDLSKSSAVPMGSHSEEVALQTLLEAKGNSAAAVLTLLQTQSSAFQMKWTAYELEQFLRGLEKHGKDFGKIANELLTKTSGECVQMYYFWKKLCVDYKVSHLKMEPVTPVTPTVEQKPYVCEIPDCSASFSSKAALHGHVRIHAYHGRNASNNNNHNSNNNNSNNNNSNNNHNNNNQHATAVSANSNSNNNNHSCNSSNSNNACAPPTSNNTNHCINATIATATAATTTIINLNNNNNNNSNNMGHPLAQNAILLATVAATTTTATSAALKDNSNSQSQSQSQSNISNTNLVKDTEFPCKVCGKVFNKVKSRSAHMKTHRVQDADQTANAKHQPNAHSTAASVTATASVAAAVAAAAAAAASLATSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00901437;
90% Identity: iTF_00901437;
80% Identity: iTF_00901437;