Laer000724.1
Basic Information
- Insect
- Liodrosophila aerea
- Gene Symbol
- -
- Assembly
- GCA_035045005.1
- Location
- JAWNNL010000126.1:240015-242045[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.88 64 4.4 0.7 2 23 246 268 245 268 0.92 2 10 0.045 3.3 8.5 0.7 6 23 277 294 277 294 0.97 3 10 0.00045 0.033 14.8 3.2 1 23 300 323 300 323 0.93 4 10 0.00036 0.026 15.1 2.2 1 23 331 353 331 353 0.96 5 10 7.1e-05 0.0052 17.3 0.4 2 23 359 381 358 381 0.96 6 10 0.15 11 6.8 0.1 2 23 387 408 386 408 0.95 7 10 0.57 42 5.0 4.2 2 23 417 438 416 438 0.92 8 10 0.00029 0.022 15.3 0.9 2 23 446 468 445 468 0.95 9 10 8.8e-06 0.00065 20.1 0.6 3 23 476 496 475 496 0.99 10 10 8.8e-05 0.0064 17.0 8.2 1 23 502 525 502 525 0.98
Sequence Information
- Coding Sequence
- ATGATATGCCGCCTGTGCCTGAATACTTCTGACGACaccatacaaatatttgacgGCGTCGGCTTGTCCCTAAACGTTGCCACAGTCTTAGCCAAATATTTTTGGTTTCAGCCAAAAAGCGATGATCCCATTTCCACCGATATCTGCATGGCCTGCTGGACGCACGTCAGCGATTTCAATGAGTTCTATACGAACGTGGAGAAGGCGCATCGCCTACTGACCGAGCGCTTCTCGTTTAAAACCGGCAGCGGAAGTGAAACGCTGGAGAAGATATCCCCCAAGGAGGAAGAGAAGCAGCTGCCAGAAGATGCGCACAGCGAAGATGATGTGGATAATCAGATGATGCATGACGACGCCCTGTATGGGAGCGGCAATGAGAGCGATGCAGCATTTAGCAATGAGCGGTTCCTCAACGACATGGTGACTCAGCATGATGACACTAATGCGTTGGAGTCCACTGAGCAAAAGGAGTCAGTGCTGCCAGAGCTAACGCATCTTGAACCCGAGCCAGAACGTCGACAGACACGTGCCACCCGGGCCAAGAGTAAAGCAAATGCAGTACTTGCTGAGGAGCCTCCGCCAGTGGCGAAGTCAGCGCCAGTCAAACGTAAAGGCAGAACAAAGACGGCTAAGACGACTGCAAAGCCTGCTGAGCTGCCGCGAAGCAAGCGTTACGTCGACTACAAGAAGTCCATGATAGAGATTGACGAGAAGATTGCGAATCATATGAAACTCatttgcaacatttgccaAGAGGTCCAGGAGACATTCCTATTGCTGTGCAAACACATGATGCAGGAGCACAATCGCAAGGGTTATGCCGTGTGTTGCAACAAGAAATTCTACAAGCGTTCCTTTCTCACCGATCACATTGATTTGCACTTCAATCCGGAGAAGTTTAAATGCAATCTGTGTGAAAGAACGTTTGCGGACAAGCAGTGTCTGCGCAATCATGAGCTGCTCAAGCATCAACCGGATGAGCAGAAGACCTTCATGTGCGAGCACTGCCCGAAGAGGTATACCAAACAGTATTTACTGGATCAGCACAGGGTCATACACAAGGAGCGTAATGTGCCCTGCGATATCTGTGACAGACGTTTTCCTAATGTCTCCATGCTCTGCACGCATGTAAAGATGGTGCATGGCAATTATGGCACCATGTGCGACATTTGCGCTCAGGTTATACGCGGTCGTGCGGCCTTTCAACGTCATCAGCTGGAGCATGCTGGCGTTACGGAGCCCAAGATCCAGTGTGACATCTGCGGCTCTTGGCACAAGAACAAATACAGCTTGCGGAAACATGTGCGGCGGCACAATGGCTCCTCGGAGGAATGCACCTGCAACATCTGTGGCAAAATCTCACCCAATCGCAGCGCGATGCTTAGCCATCAACGTTATGTGCACAATGCTGACCGCGTGCATGGTTGCAGTGTGTGCAATAAGAAGTTCAAGAAAGCCATCAATCTCAAGGAGCACATGGCCACCCACACGGGTGAGGTGCTCTACAAATGTCCACACTGTCCCAAAACCTTCAATTCGAATGCCAACATGCATTCGCATCGCAAGAAATGCCATCCTAAGGAATTCGAAGAGGCTCGCAAGGCACGACTACAGAATCGCATGGAGCCCAAAACAGATGAAGTGAGTGATAAAACCAATTTGAATATGATAACGATAACCACAGAGAGCGGAAGCGGTGGACAGCTGGAGACGCACAACATATTGGtgaccaccaccagcaccacggGGCACAGCGATGAAGAGGAGGGGGAATTCAAAGGTGAGGACATTGAGTTCATGCTCTCGCTCAGTCCACAGCCAGCGGAATAG
- Protein Sequence
- MICRLCLNTSDDTIQIFDGVGLSLNVATVLAKYFWFQPKSDDPISTDICMACWTHVSDFNEFYTNVEKAHRLLTERFSFKTGSGSETLEKISPKEEEKQLPEDAHSEDDVDNQMMHDDALYGSGNESDAAFSNERFLNDMVTQHDDTNALESTEQKESVLPELTHLEPEPERRQTRATRAKSKANAVLAEEPPPVAKSAPVKRKGRTKTAKTTAKPAELPRSKRYVDYKKSMIEIDEKIANHMKLICNICQEVQETFLLLCKHMMQEHNRKGYAVCCNKKFYKRSFLTDHIDLHFNPEKFKCNLCERTFADKQCLRNHELLKHQPDEQKTFMCEHCPKRYTKQYLLDQHRVIHKERNVPCDICDRRFPNVSMLCTHVKMVHGNYGTMCDICAQVIRGRAAFQRHQLEHAGVTEPKIQCDICGSWHKNKYSLRKHVRRHNGSSEECTCNICGKISPNRSAMLSHQRYVHNADRVHGCSVCNKKFKKAINLKEHMATHTGEVLYKCPHCPKTFNSNANMHSHRKKCHPKEFEEARKARLQNRMEPKTDEVSDKTNLNMITITTESGSGGQLETHNILVTTTSTTGHSDEEEGEFKGEDIEFMLSLSPQPAE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -