Basic Information

Insect: Liodrosophila aerea
Gene Symbol: Hivep2_1
Assembly: GCA_035045005.1
Location: JAWNNL010000649.1:66790-75294[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0002 0.015 15.9 0.3 1 23 207 229 207 229 0.98

2 8 0.0003 0.022 15.3 2.9 1 21 235 255 235 259 0.89

3 8 0.0097 0.71 10.6 0.2 1 19 901 919 901 922 0.93

4 8 2.7e-06 0.0002 21.8 2.0 1 23 1615 1637 1615 1637 0.99

5 8 1.1e-05 0.00084 19.8 5.3 1 23 1643 1667 1643 1667 0.92

6 8 6.8e-05 0.005 17.3 3.5 2 23 2116 2137 2116 2137 0.97

7 8 0.00078 0.057 14.0 1.2 1 23 2143 2167 2143 2167 0.91

8 8 0.0025 0.18 12.4 2.7 1 23 2188 2212 2188 2212 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0002	0.015	15.9	0.3	1	23	207	229	207	229	0.98
2	8	0.0003	0.022	15.3	2.9	1	21	235	255	235	259	0.89
3	8	0.0097	0.71	10.6	0.2	1	19	901	919	901	922	0.93
4	8	2.7e-06	0.0002	21.8	2.0	1	23	1615	1637	1615	1637	0.99
5	8	1.1e-05	0.00084	19.8	5.3	1	23	1643	1667	1643	1667	0.92
6	8	6.8e-05	0.005	17.3	3.5	2	23	2116	2137	2116	2137	0.97
7	8	0.00078	0.057	14.0	1.2	1	23	2143	2167	2143	2167	0.91
8	8	0.0025	0.18	12.4	2.7	1	23	2188	2212	2188	2212	0.92

Sequence Information

Coding Sequence: ATGACGCTACAACATGTGGCAAGCAGCGTtgccagcggcagcaacaccaacgacaacaatcagagcagcaacagcattgtGTCGGCCACAGTCAGCGATGAGacgccggcagcagcaacaacattcgGCGAGTGGACAAGTGCCACAAATTCTCGCTATTTGCATAAGAAGTTTAAGCGTTTGGCCAGCACCACCGAGGCAGAGACGGCGGCAACAGTTGTTGCCGGGCAGCGCAGCACATCGTTGTCATCCAACAGCTCGGTGTCGCCGCCACCCGTGGCAACAGCAatcgcaacagcagcaacattgctCAATGGCCATgtgacggcaacaacaacaaatgaattcAGCAATTGCCATgacgagagcaacaacaacaacagcagcggtaagaatgttgctgctgctgttgttgtggcacgCACACCGttgagcaacagcaatagcaattaTGCCAGCAATGCCACATTGTCGCCAGCAACATTCgcccagcatcagcagcagacgCAGCCAACAACCGCTGCTGCCGTCACAGCTGCAACAGTCACCATTGCCACAGCACCACCAACGgttgcagcatcagcaacaccaacaacacctGCCGAAAAATCCGGACGCTATGTCTGCCCCTATTGCAATCTGATCTGTGCCAAGCCATCGGTGCTGCAGAAGCACATACGCGCCCATACCAATGAGCGCCCCTATCCCTGCGACACCTGCGGCATCGCCTTCAAAACCAAGAGCAATCTCTACAAGCACTGCCGCTCCCGCTCCCATGCCGCACGCATGCGCGGCTTCGAGGTGCCGCCCCATGAGGCGGACGGACTCTCCGATCAGGATGGCGATGGCGAgctgagcaacagcagctccgAGTTGTTGAGCGTCGATGTGCTGAGTCGCACGGATTCGCCCTTTGATGAGCCCATGGCCTCGCCCACGCCCTCGCCCTCTACTCTGTCGGCAGCGAAGAGCGCTTATCTGCAACAGCCGCCATTGCTGCAGCAcatgcaacagttgccactgGGCTCGCCAGCAGCAGGCACGCTCCCGCCGGCAACAGCTGATACGCTGCACTCGGCAACAGCTCAGCATCGGCAATCGATAGACTACAAGCCATACAAGCCCAAGTTCCACAATGCATCGCTCTATGCGCCTGGCAGCAGCAAGGAGCAGCAggcactgcaacagcagcagcagcaacaacagcagcagcagcagcagcaagtgttgcagcagcaggcaatgcaacagcagcagcaacagcagaagctaGCGACTCCTCAGGCACAGCTGGCGCATCCGACGCTCTCGCCGAGCACACAGCTGAAGCTGAACAATCACATCAATTCGCaccaattgcagctgcaactgcaacatcagcaccagcaacatcaacagcagcagcaacatcagcatccATCATTGCtgttggcagcagctgctgctgctggtggcaatCCCGCTGCATTGACAGCACTCGCTCCACCTCCGCCGCTGCCCACGGGTGTGTTCTATCTGGGACAGTCGCAGTATTACAATCccgcggcagcagcaatgcaTCAGCATGCCTTGGCATttcagcaactgcagctgcagcaacactttcaactgcagcagcaacatcagcagcagcaacaccaacagcagcagcagcagcagccacaacactCGCCATTGCTAAAGGCACCGCTGCAACAGgcgccgccgccgccaacaGCCactgcacagcagcagcagcaacagttgccgccgcaacagcaacagCTACTCCGCTCCAACAGTCAGCAATTGTCGCTCACCGCAGCAACACCCgcccctgccacgcccacaactgCCAGCAATCTAAGCAGCTTTGCCAGTGCCAGCGGTGGCATGCAAGTGAATGTGGAGAAGGTGCAGGAGCACATCTCGAAGCTGATCTCACAGAACGAGGCCATCGTGGAGAACAAGGAGATACTGCTGCAGAAGAAGTATCCCAAGCAGCTGAATCGTTCGCGCAGTTTCAACaacgccaacagcaacaacaacaacaacaccggcagcaacagcaacaccagcggcggcagcagcaacagcatcacgcacgccggcaacagcagcaacagtcagcAATTGGGGGAGACCAAAGTGAATCTGGCACAGGCTATAgtgcaaaagcagcaacagcagcagctgcagcagcagcaaatgcagcaacagttgcagcagcagcaacagcagcagcaatatcaaATCtatatgcagcagcagcagcagcaattggagCCCGTCAATGGACTGCTGAAGCGTGCCAACTATGCCAGTGCGAAGGCCACGTCGTCGCCAGCcaagctgccgctgcaacagttgccgccaCCGCCGTCAGCAATGGCCATGCAGACGCTGCAATATCGTCAGGatccagcaacagcagtgcccaagctggagcagcagcagcagccgaatCATGCGCAGCCCTTGAATCTGTCCGCCAAACCGAAGCCACTGGccaaaacagcagcagcagcagttgccccagcaacagtaactgcagcagcagcaaccatagctgtcacagcagcagcagcaacaactgcaacagttgctgtgcCCAAGAGCAACATAGCTGTGGCACAGGCACCAAATAATTCCATTATAAAGAATCTATTGCTGAATGCGCGGGGTTTGGCGGTGCCCATTGGCGAGGGCGACGATGCCGTCTACTCGTGTCCCATTTGCGCCAATGAGTTCCGTTCGGCGGATGAGCTGAAGCACCACAACAGCACCTACTGCCAGGATGCCAACAGCAGTTGCCCCATGAGTCCGGCCTCGTCGCCCAGCAGCAAATACTTTCGCTCCAATTCCATATCGATGAGTCTGCCCGAGCTCAAGTCGCACATGGCCAACTCCAAGAATCCGCTCTCGCTGGCCAAGTTGGCCTGGTCCCAGCTCAAGACGAAGCCCAGCAGTCTGGTGCTCAGTCGCTTGAATTCCGCACAAACTCCGccacgcaacagcagcagcagcagcagtagcagcacagcagcagcagcagcaacagccactgctcccagcaccagcagcaatcCTCCCGCCGTAATCCCGCCCAGCATTGATGCCAGCAATGTGGCGTTGCGCTTTGTGGATGCACCGCTGCCTTCACCTGGACCACTGCTGGGCAAGACGCCTCTGGTGGACTATGCAGCGCCACGCAAGGCACAGGATCAGGTGGTCATCACCAAAATGCATGAGGATCGGCCGGAGAACATCATACTGGACACGCCCAGCAAGCGGGCGAAGCTGAGCAACGACGCCAGCTCTGCCAGCTCAGGCTCCTCTGCCTTTGCTCTGCCCACGGGGATGCAGTTGCTCTTTAGCGGCGCCAGCCAGGAGCTGAACAACAGCTTTGGTGGGAATAAGGAGGAACGACTACGTCGCTTCACCTCGTCCGGCGGCAGCATGATACCCATTTCCGAGTGCCCCGAGCTGGACAAGAGCCCCAAGATGATACGCACGCCACTCTTATCCGGTGGCAGCTTCCAGGAGATGTCACCACGTCCCAGCGAGGCCAAGGAGCGCAAGCTGGCGGGGCACAACAATGGCTATCCgcagcattttcaatttccgcCCATCAATAGCATCACTGCCTTCAACCCACTGACGCTGCCGCCAATGAGCACCAGCATGGAGATGAAGCCCATACCCTATGTGCCGGGCATACCAGGACCGGGTAGCATGACACTATTGCCGCCGCcccagcagctgcagttgcccaGCGGTCGCGTGCGTAGTCCCAATCGCAAGCAGCCCAGCCCCAATCCCCAACAACTGCTGGCTGTCACGGATGCAGTGCCTCCCATGAAGGCGCTGTCGCCCTTTGGCGGGGTGCAGAATCTACCCAGTGAGTTCAGTCGACAGCCACCGACACCGGCTCAACGCAGCGCCTTGCAGTGGAACAGCAGCAAGGgagcgacgacaacaacagttgccggcgcagcagcaacagttgccaagCAACCATTCAATTTCCTGCGCATGGCCGAGAATGTCAAGGAGGAAGTGCGTCATTTCAACTTTGAGCAGCTGCAGAAGGCACCCGAGGCGCTGGCACCATTGCATGTGGAAACACCGGATGAGTCGGTGaccagtagcagcagcacgcCCTCCACAGGCACTGGCTCAGCCACCACACCCAGTGGCAGCGCCAAGTCCAAGTTTCTGCGTCCCACCAGTCTGCCCCTCAAGCCGGGCACCTTTACGCCCAAGCGGCATCATGGGATTACGCCCACGGCCAATACGCTGCCCCTGATCTCACCGGAGACGCCACGCCCGTCCAAATCCTGCGTGCAACTGTACCTGAATGGCCACGCCTACACGTACCTGGGACTCAAGTGCAGCACCAAGATGTTCTACTGCACCGTGAACTGTCCACAGCCGTCGTATGTGGCCGGGATGCACAAGCTCTCGATGTACAGCGTGTGGCAGGTGTGCGAGGAGAATCAGCCGCATCCGCTTGGCTTCAAGCCCAAACAGGTGATGGCTCTGTATGATTCGCGCCAGAAACTGGGCAACTCGATGTCCATGGCGGGCGTGGGGAAACTGCACTACGCCCTGGTCAGCTCCCAGCAGATGGTCAGCAGCTTCTCCACCACAGCGAATGGAGTCCAGAGCAAGTGCTATCAGCATCAGCCCAAACAGCCGCCGGCCATTGCGGCGCTGAGTGAGGCCAATGTGGCAGCCAAGGCCAGtcaggatgaggaggaggcggCGGCGTCCAAGAAACTGGAGACGGGACAACTCCTAGTGGGTGGCTATGAATCCCATGAGGATTACACGTACATACGTGGACGTGGACGCGGGCGCTATGTGTGCTCCGAGTGTGGCATCAGGTGCAAGAAGCCATCGATGCTCAAGAAGCACATACGCACCCACACGGATGTGCGTCCCTTCACCTGCAGCCACTGCAACTTCAGCTTCAAGACGAAGGGTAATCTCACCAAGCACATGCAGTCCAAGACGCACTTCAAGAAGTGCATTGAGCTGGGCATCAATCCGGGTCCCATGCCGGCGGATGGTGAGTTCCTCGACGTGGATGTCGAGTTTGATCAGCAGTCCAGCACCTCGGCAGGCGGACGCACTAGCTCCATGGCGGGCGAATCGGACTCTGATGACTACAGCGACAATGAGTCGGAGAGCAGTGATACGGATGAGAGCAAATCCCGCCTCAAGGAGCACGAGGCGGCACGTGGCCTGCTCTCGTTGTCCATGACACCGCCCATACCACAGAGCGTCTCACCCTATCCCGCCCAGCTGCAGGAGACCACACCCGTGCCCGCAGCCAGTCCAGCGAACAGTATCGGCTCCTCGgcgggcagcagcagtgccgCGACACAGCCCAAGCGTCTGGTGTGCTCCTTTACCTCGCCCAAGCCACCGTTTGACTATCAGAAGCAGGAACAGTATTACTCCAATCCGGAGGAGTCCAAGCCCAAGCGTGGCGTGCCCAGCGATGAGAGCAGCGCACCCATGGATCTAACCAAGCCACGCACAGCCTCGGCGGGTTCCTCACCAGCGCCAGCGCCACTGACTGACCAGCTCCTGCCCAAGTCACAGGCGCAACAGATGCGCGATGTCATCTTTGGCGCGGGCAACAATGAGTGCGGCTTCATGAAGACCCTCATCTCGGTGTCCGACAAGGTGCGCATCTCTGCCGAGATGGAGGAGCAGGCAAAGCGCGAGAGTGAGGGCGATGATGTGCTGCTCCAGACCTACATCAAGGAGCAGGCGCTGCAGTACGCCAAGATGAAGCAGAGCCAGTTCAGTCGCAGCTACCAggtgagcagctgcagcagcagtagcatcaGCTACAGTTCCGCCTCGCCCATCATGTCCAGCTGCGTGAGCAAGCCCATCATGGAGCTGCCCAGCATTGAGGTGAGCGAGGTGAAGACACCAGAGCCACCACCAGCGGCTGAGGCCGCCAACAAGTCAGCGGAGGAGAGCAGCGCAGAGGAGACGGAGAGCCCGGCCGAGGAGCCagagcagccgcagccgcagtcCAAGGTGGCAGCCAAGCCAGAGCATAATGCCAACTTGCCTGCTGCAGTGCAGCTGCCGGATGCCACGGACTTCACGGGCgtgctgagcagcagcaagagcagcacgatcaccagcagcagcagcaccaccaccacaccaGCTACTCCAGCACGCGCGGTGGTCGTGGTCGAGGAAGGCTTCaaggccacgcccaccacgaGCATCAgtaccaccagcagcaccaagACAGAGTCTGTGCCTGTGTCCACTGCCTTCCCTCGTGTGGtggcaccaccgccaccacccaTTGCTGGGGATGCGCGTCCCACCTGCAGCGTCTGCCAGAAGACATTCCAGCGGCAGCATCAGCTGACGCTCCACATGAACATCCACTACATGGAGCGCAAGTTCAAGTGCGAACCCTGCAGCATCTCCTTTCGCACCCAGGGACACCTGCAGAAGCACGAGCGGAGCGAGGCGCACAAGAACAAGGTGATGATGACGTCGACGTTCGGTGTGCCGACCACATCGAATCCGCGTCCCTTCGAGTGCACCGACTGCAAGATCGCCTTCCGCATCCACGGCCATCTGGCCAAACATCTGCGCTCCAAGACGCATGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCCTTCGGCACCTACGCGGAGATCGAGCGCGCCGGGATTAGTCTGACCGAGATCGATACGAGTGACTGCGAGAACTCACTGATCTCACTCAAGCTACTGGCACAGAAGCTGCTCGAGAAGGATCCCAACAAGCTGAGTGGCTATACCACTCCGTCGGGCATGCTGCAGCTGTCGGGGGATCCGCCTGCCGCTGGCCAGGACAGCGCCTCGGAGGATGGCTTTAGTGCCGCGAATAGTGCTGCTGCCTCAGCCATCGCTTCGCTGGATAATGACTCCGCTGGCAATACACCACAGCGGGCCAGCTCCATGTCCGAGGATGAGAGTCTGGCCAATGGCATCGGTCATGCCACGAGTCTAAAGCGTCGCCTCCCAGGCAGCAGCTTCAGCAGCAATGGCGATGAGAGCGATAATCCTCTAGAGGGCAGCGAGAAGCGTGCCAGGAGCAACACCAATGAGAAACTAACAGCAGCGCTGCCTGTGGTCGCCTCCACGGCAACAGCCAGCAACTGA
Protein Sequence: MTLQHVASSVASGSNTNDNNQSSNSIVSATVSDETPAAATTFGEWTSATNSRYLHKKFKRLASTTEAETAATVVAGQRSTSLSSNSSVSPPPVATAIATAATLLNGHVTATTTNEFSNCHDESNNNNSSGKNVAAAVVVARTPLSNSNSNYASNATLSPATFAQHQQQTQPTTAAAVTAATVTIATAPPTVAASATPTTPAEKSGRYVCPYCNLICAKPSVLQKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARMRGFEVPPHEADGLSDQDGDGELSNSSSELLSVDVLSRTDSPFDEPMASPTPSPSTLSAAKSAYLQQPPLLQHMQQLPLGSPAAGTLPPATADTLHSATAQHRQSIDYKPYKPKFHNASLYAPGSSKEQQALQQQQQQQQQQQQQQVLQQQAMQQQQQQQKLATPQAQLAHPTLSPSTQLKLNNHINSHQLQLQLQHQHQQHQQQQQHQHPSLLLAAAAAAGGNPAALTALAPPPPLPTGVFYLGQSQYYNPAAAAMHQHALAFQQLQLQQHFQLQQQHQQQQHQQQQQQQPQHSPLLKAPLQQAPPPPTATAQQQQQQLPPQQQQLLRSNSQQLSLTAATPAPATPTTASNLSSFASASGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANSNNNNNTGSNSNTSGGSSNSITHAGNSSNSQQLGETKVNLAQAIVQKQQQQQLQQQQMQQQLQQQQQQQQYQIYMQQQQQQLEPVNGLLKRANYASAKATSSPAKLPLQQLPPPPSAMAMQTLQYRQDPATAVPKLEQQQQPNHAQPLNLSAKPKPLAKTAAAAVAPATVTAAAATIAVTAAAATTATVAVPKSNIAVAQAPNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKHHNSTYCQDANSSCPMSPASSPSSKYFRSNSISMSLPELKSHMANSKNPLSLAKLAWSQLKTKPSSLVLSRLNSAQTPPRNSSSSSSSSTAAAAATATAPSTSSNPPAVIPPSIDASNVALRFVDAPLPSPGPLLGKTPLVDYAAPRKAQDQVVITKMHEDRPENIILDTPSKRAKLSNDASSASSGSSAFALPTGMQLLFSGASQELNNSFGGNKEERLRRFTSSGGSMIPISECPELDKSPKMIRTPLLSGGSFQEMSPRPSEAKERKLAGHNNGYPQHFQFPPINSITAFNPLTLPPMSTSMEMKPIPYVPGIPGPGSMTLLPPPQQLQLPSGRVRSPNRKQPSPNPQQLLAVTDAVPPMKALSPFGGVQNLPSEFSRQPPTPAQRSALQWNSSKGATTTTVAGAAATVAKQPFNFLRMAENVKEEVRHFNFEQLQKAPEALAPLHVETPDESVTSSSSTPSTGTGSATTPSGSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPKQVMALYDSRQKLGNSMSMAGVGKLHYALVSSQQMVSSFSTTANGVQSKCYQHQPKQPPAIAALSEANVAAKASQDEEEAAASKKLETGQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVEFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRLKEHEAARGLLSLSMTPPIPQSVSPYPAQLQETTPVPAASPANSIGSSAGSSSAATQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRGVPSDESSAPMDLTKPRTASAGSSPAPAPLTDQLLPKSQAQQMRDVIFGAGNNECGFMKTLISVSDKVRISAEMEEQAKRESEGDDVLLQTYIKEQALQYAKMKQSQFSRSYQVSSCSSSSISYSSASPIMSSCVSKPIMELPSIEVSEVKTPEPPPAAEAANKSAEESSAEETESPAEEPEQPQPQSKVAAKPEHNANLPAAVQLPDATDFTGVLSSSKSSTITSSSSTTTTPATPARAVVVVEEGFKATPTTSISTTSSTKTESVPVSTAFPRVVAPPPPPIAGDARPTCSVCQKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLSGDPPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDESLANGIGHATSLKRRLPGSSFSSNGDESDNPLEGSEKRARSNTNEKLTAALPVVASTATASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -