Laer002748.1
Basic Information
- Insect
- Liodrosophila aerea
- Gene Symbol
- -
- Assembly
- GCA_035045005.1
- Location
- JAWNNL010000401.1:962-7414[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.044 3.2 8.5 0.3 1 23 1338 1361 1338 1361 0.94 2 13 8.1 6e+02 1.4 0.2 1 23 1530 1552 1530 1552 0.91 3 13 0.00018 0.013 16.0 2.7 2 23 1555 1576 1555 1576 0.97 4 13 7e-05 0.0051 17.3 0.2 3 23 1584 1604 1582 1604 0.98 5 13 5.8e-07 4.3e-05 23.9 4.1 2 23 1611 1632 1610 1632 0.97 6 13 5.5 4e+02 1.9 0.4 5 23 1645 1663 1643 1663 0.96 7 13 1.4 1e+02 3.8 5.4 3 23 1670 1691 1668 1691 0.93 8 13 0.32 23 5.8 0.2 2 23 1702 1722 1701 1722 0.96 9 13 5.6e-05 0.0041 17.6 0.4 1 19 1728 1746 1728 1750 0.95 10 13 1.6e-05 0.0012 19.3 0.5 1 23 1758 1780 1758 1780 0.98 11 13 0.0001 0.0077 16.8 7.6 1 23 1786 1808 1786 1809 0.96 12 13 0.0002 0.015 15.9 5.9 1 23 1814 1836 1814 1836 0.98 13 13 0.029 2.1 9.1 8.2 1 23 1842 1864 1842 1865 0.95
Sequence Information
- Coding Sequence
- ATGGCTGACAGTATGCAGTGCCCCGTGTGCACGCTGTACCTGCATGCGGGTATGAACCTCTCCGATCACTTGGAGACGCATCCCAAGGAGCAGGTGATCAGGGCTCTGGTGCAGATGACAATCGTTGGCACTAATCCTGCCATGACCCAGGCGGCGCTGGCAACAACTGCGCTCTCCACTGCTGGCAGTGGATGtggtgcaacagcagcagcagatggcTGCGGCACCGGCAATGGCACTTCCTCCTCAACATCGACATCAGTGGCATTAACGACTGACGTTGATGTGAAACCAGTTGTGCCAgccatagcaacaacagcagcagcagcaacaacaacaacaccagcaacagcagcagcagcaacagccacaaaatCAGCAGCAAGCAAAGCTGTGCTATTGCTGGGAAATGCCAGTAGCAACAATACcaatagtagcagcagcagcagcagcagcagcagtaccagtagcagtagcaataataacaaattgaacAATCCACCGATTAAAGCTGTTAAAAGCGCGCCACCTTCGACTGAGGCGCCGCCAGTCCCCACATCCAACACACCCACCATGAGCAGCGTGACTGCCATTTATCCGCCAACACTGACATCCGACTATCGCTatccgcaacagcagcagcagcaacagctgcagccactGGCGACAGCGACAAGCACACTTCATGGCTTTGCACGTGGTGGCACCACGACGCTGGTGATACCAcaagcagcacagcagcatcACTTCCTGGCcagccaacaacaagcagccCACTttgcccagcagcaacagcagcagcagcagcagtcggcaATGAAGTACACATATGCAACAGCGCTGCCACCACCCCCGCCGCCCCTGCAGCTCTTTGCACAGCAGCCGACGGCAACGCAGTCGCAGCACCAGAAGCCACCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGcacaaccaaaacaaacagcagcagcagcagcatatagcTGTGCAGCATAATGTTAACCTAACACCACCGAGTGGTAAACACAGCAAAGCCCAAACGGAGATCTTTCTTAATCCACCGCCTCCACCACCTCCTccgtcacagtcacagtcacagtccaCTTCGTCGCAGGCACTGAGCTCTTCCTTGagactgcagcaacagcagcatcagcagcaactgcagcaacaatcgCCTGGTAGTTATGCCAATGCCAACTGCAGTAGCTCCACATCGGCTTTACTCATATCGTCCACATCGACGGCACGTGGTAGCAATAGTCGCCAGTCGAACAGTTCACCATTTGGAGCTCTACTGAATGCAGCTGCTCATGCTGCTTGCGCCTCGCCAGCCCCGTCCTCGGGCGCTCCATCTGTCTTACGCTATGCTGAATCTCCGGTAGCCCACTATCTAGAGCGAGAAAATGGTGACTTTATTGTACAAGAGACACCCAAGCATATTGTGGAGTGTGTGGAGAAGGACGACGGTGAGTTCTCGGTGATTGAACGCATCTACCATTCGCCACCCAGCGTGCTGCACATactcgacgacgacgatgacgaggaGGACCACGAGGAACACGGCTGGACAAACAGCGAGGAAGAGCAGCACGTTAAGCAGTCGCATAACCATGTGGAGGATGGCGATGATGAGCGCGAGGATAGCCGCAGTCGAGCTGGACTTAAGAGTTCAACGAAAAAGATGCGCAAGACAAAGGCCGGAAGCAGGGCACACAAACGCTCCACCAGGCAGcaccagccacagcagcaacatccgccagaggatgaggaggatTTCATGAGTgttggcagcagctgtgccGAAAGTGAGCTGCAGGAGGAGCACCAGCCGCAAGCGTCTCCAAGTGTAGCACCAACGGCAACAGCCTCGCAAGCGTCAGCTCCGGCAGAGATCTGCACGGCACCGTCGACAAGCAGTGGAGTAGCTGGAGCTGTTGCATCGGCCAATGGCAACGCTACATCTAGCACCAAGTCCAAAAAGAATCGCGTTACGGTGCTCAGCGATGTGCCactaaatatgaatgaataccTGGATCTGGTGGGGAACATAGTGGCTTCGAGTCGCATTGGCGCCTCGCGTCCCTTTGCTGCTGTGCCGTCCGTCCCGTATGTAAAGGTGGAAAAGGAGGAGCCATTGGATGACTATGATGCCGTGCAGCTGACAATGGAGCCGAAGTCCGGTCTAGAGCATGCCAGTAGCCACAGCAGGAGTAGCAGTTGCGGAAGTAGCACCAATGGACATGGCACCACCAGCGTTATTCGCATGCCAACGACGTCGTCGGCGCTGACTGATTTcaaagtggaagtggaagccACACAACTGATACCGCAACGCTTCTCAGCGCCGGCCCAGCAGCGTGGACCCAAGAAGTTGGTCATCAAAccaaaggcaatggcaatggcaacaataacgTCGATACCGACTAAAAAGActgataacagcagcagcagttgtgcTCCTGAATCTCCTAGCATATCAGCTAAAGCGCCAACTGCAGATCACGTACAGGTCAAGAGCGAGACTGTGGACCCGGCAGCCATCAGTGGCAGTATACTGGAGAAGCATCTGACCAACAAATATGCTGCTGTCGCCACCGCACATGCCTCCTCCTCTGGGCAGGGACGCAAGCACTCTTCCGTTAATGATGACGATGCACGGGTGTTGCTGGAGTTtgccaactccaactccaagcagctgccacaggCAGGTACCACCTTTGTGGTGAATGCAGCCAGCTTTGCATCGGCAGGATCTGTATTTGCCAGCGGCAGCACTGTGGGCAAGTCGAGCCAACCGGGCGATGAGTATATAGTGCCTGATGATAATCTAGACGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTTTGCCTCCACcacgcagcaacagccacacccacacacacatcatcatcagcagcagcagcagcagcaacaacaacaagcgacacaccagcagcaacaacagccacagcaggcGCATTCCTCGCAAGCAACGCTGCAGCCAATTGGTTTCaatgatttcaattttctatacCATCATAGCACAGCCGCAACGACTCCAACTGCTTCCAGCTTTGCACCATTCGGcttgcagcatcagcagcagcagcagcagcatccacacGGCTCTAGTGAAGCCACCAATGCAGCCACGCTTGCTTCATCATCCAGCAATAGCTCAGCCATAGATCAGGACTGTTCCATGAATGCCACGTTCCGTATGGCCAAGTCACAATCGACGCTGAGCAACTCCTGGTATCAAGCGCAaccccaacagcaacagccaagcAGCTCCCACAGCGTGGAGCATTCGAGCAACTTCATTGCTGCCCTGGCAGCCGTTGAATGCTCCAACGTGGCGGTGGACAGTGATGCAAGTGATGCCAAATACTTGGACCTCGACGCCTGTAAGCgagagcaactgagcaatagcagcagccaTTTACCCTCGGCATCAGCATCCACATCGACCACATCGTCATCCTTTGCGGCTGCCGCGACGGAGAGCAGCCTGGTTGGGGGCTTGGGCCTCAATATACGCACCGATGAAAAGATGCCTGCCAAGGGTGAAATTTCCGAGCAGGAGAGCAACTGCGACATAGAAAACTCGTGGAGTCAATCCATGTACGGAGACATATCACAGCGTTACTTCAGAAATCAGTTCACGGATGGCTACAATCAGCAACTGGCCGATTGGCGTCCGGATTACTATCCGGCCCAGGATCTCAGTGGTCAGCCAGAGCAGACGGAGCAACGTGAACACAAACTCTTTGACTTCAATGCGGTCAACTCGGAGTATGCGCCAGCAGGTAATATGGATGCCTCGTCGAGCTCTGCACGCTGCAATCAATTGCTGGATGCACAACCCACCACTTCATCGTCATCGGCTCTAATGGCTGGCTCACCCATAGCCTCAACGTCACGTGCTGCCGCCGAAGCGGAGGCAGCTGTTGCAGCGGCATTGACTCAACGGAAACCACCACGTCGCAAGATCTACAAGTGTCCCCATTGTGTGGCCATCTTTGAGAAGCTAAAGGATCGCAATGCCCACATGATTGGCGAACACAACTATGTGCGGCAGAATCGCCGTCTGATCTGCACTCAGGCGCTGATCAATGCCACCATCTTGAGCCAAACCCAggagctgcaacagcagcagcagcaacagtcggagcaacaacagcaactgttgttgcagGCAGCAGGTGGCAGCAATGGCGATATAATGCATGAAGATTCCAAGGATGGCATTGTGAAGATCAAGCAGGAGAACTGTCCGGATAAGAATGATGCAGCCGAGCAGATGCTCGATCATATGGGTCTGCCTGATGTCAAGGATGCCGATTTGCTTGACGCCTCTAGTGCGGAGAATGCACGTGAGCCGGACATTAAGCCACCGACCAGTGAAACGGAACTGGATGAGAAGCCGACCATCACGCCGTTGACCATGACAACACCAGCTGCAAAGCTGGCGGCAATTTATCGCATGTTAATCACATACAATGAATCAAAGCTGGGGCAGGAGCGCAATATCAGTGAGCTGGAGAAGAAGGCCATGGAGAAGTCCATATTCTTATGCTATGTCTGTCGCACCGATTTCCCCTCGGTCAAACTGTACGATGCGCATCTCACGGAACACCCGGCCGAATGCTTCACCTGCGGCAAGAAGTTCTACCGTTGGAAAAACTTCTCGTTGCACTTGAAGCGTCACCTGGGCTGGAAGGAGTTCGGCTGCTATGTCTGCGATAAGAAATTCGTTGTGCGCAGCGCACTCGTGGAACACATGCGTATGCATACGGGTCAGACACCATTGAAGTGCAAGATTTGTGGTAAGAAATTCAAGCGCTACTCAAATTTGACGCAGCATCGCAAGCGACACAACAAGATCAGTGTGCGCAAGAAGGAGTATGTGTGCCACTGTGGCGAAGTGTTGCCATCGAAGGCCCGCTTCCTGTGGCACAAGGAGACGCATGACTTGAAGCCCAAATGCTGTCCATATTGCTGCGATCGTTTCGTGCATGCCAATTCGCTGCGCCGTCACATTCGCCTGGCGCATTCGGATAAATTCGATTATGCCGAGCCCGTGGAGTGTACGATGTGCAAGCAGATCTTTGCCAAGACGTCCATCAAGGCGCACATGGCGACCCACTCGACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCATGCGAATCGCACGGCGAAGCCCTTCAAGTGCGAGTACTGTCCCAAGGCATTTGTACGTGAGCTGGACTTCAAGAACCACATGAATGCCCACAAGCAGATCAAGCCGTACACATGCGAGTATTGCGGCTGCAAGTTCATACGGAAGTACAACTACATGCGGCATCGGCGGGAGCATCATGGCAACAAGAAGTTCACCTGTGATCAGTGCGACAAATCCTTCCATCGACACTACTATCTGATCGAGCATAGGCGCATTCATACCGGCGAGCGGCCCTTCCATTGCACCATCTGCGGCAAGAGCTCCACCACGAAGACCAACCACAATAAGCATCTGAAGATACATCATTCGCGCGATCCCTTCACTGTCGAGGTCTAA
- Protein Sequence
- MADSMQCPVCTLYLHAGMNLSDHLETHPKEQVIRALVQMTIVGTNPAMTQAALATTALSTAGSGCGATAAADGCGTGNGTSSSTSTSVALTTDVDVKPVVPAIATTAAAATTTTPATAAAATATKSAASKAVLLLGNASSNNTNSSSSSSSSSSTSSSSNNNKLNNPPIKAVKSAPPSTEAPPVPTSNTPTMSSVTAIYPPTLTSDYRYPQQQQQQQLQPLATATSTLHGFARGGTTTLVIPQAAQQHHFLASQQQAAHFAQQQQQQQQQSAMKYTYATALPPPPPPLQLFAQQPTATQSQHQKPPPAYGAAISQIRSQHNQNKQQQQQHIAVQHNVNLTPPSGKHSKAQTEIFLNPPPPPPPPSQSQSQSTSSQALSSSLRLQQQQHQQQLQQQSPGSYANANCSSSTSALLISSTSTARGSNSRQSNSSPFGALLNAAAHAACASPAPSSGAPSVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKDDGEFSVIERIYHSPPSVLHILDDDDDEEDHEEHGWTNSEEEQHVKQSHNHVEDGDDEREDSRSRAGLKSSTKKMRKTKAGSRAHKRSTRQHQPQQQHPPEDEEDFMSVGSSCAESELQEEHQPQASPSVAPTATASQASAPAEICTAPSTSSGVAGAVASANGNATSSTKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGASRPFAAVPSVPYVKVEKEEPLDDYDAVQLTMEPKSGLEHASSHSRSSSCGSSTNGHGTTSVIRMPTTSSALTDFKVEVEATQLIPQRFSAPAQQRGPKKLVIKPKAMAMATITSIPTKKTDNSSSSCAPESPSISAKAPTADHVQVKSETVDPAAISGSILEKHLTNKYAAVATAHASSSGQGRKHSSVNDDDARVLLEFANSNSKQLPQAGTTFVVNAASFASAGSVFASGSTVGKSSQPGDEYIVPDDNLDVDEIVISSSSSFASTTQQQPHPHTHHHQQQQQQQQQQATHQQQQQPQQAHSSQATLQPIGFNDFNFLYHHSTAATTPTASSFAPFGLQHQQQQQQHPHGSSEATNAATLASSSSNSSAIDQDCSMNATFRMAKSQSTLSNSWYQAQPQQQQPSSSHSVEHSSNFIAALAAVECSNVAVDSDASDAKYLDLDACKREQLSNSSSHLPSASASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRPDYYPAQDLSGQPEQTEQREHKLFDFNAVNSEYAPAGNMDASSSSARCNQLLDAQPTTSSSSALMAGSPIASTSRAAAEAEAAVAAALTQRKPPRRKIYKCPHCVAIFEKLKDRNAHMIGEHNYVRQNRRLICTQALINATILSQTQELQQQQQQQSEQQQQLLLQAAGGSNGDIMHEDSKDGIVKIKQENCPDKNDAAEQMLDHMGLPDVKDADLLDASSAENAREPDIKPPTSETELDEKPTITPLTMTTPAAKLAAIYRMLITYNESKLGQERNISELEKKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHNKISVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPVECTMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -