Laer011655.1
Basic Information
- Insect
- Liodrosophila aerea
- Gene Symbol
- -
- Assembly
- GCA_035045005.1
- Location
- JAWNNL010000982.1:466407-470055[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.013 0.93 10.2 1.2 3 23 352 373 350 373 0.96 2 17 0.16 12 6.8 1.8 2 23 416 437 416 437 0.93 3 17 5.8 4.3e+02 1.8 3.0 2 17 448 463 447 474 0.75 4 17 0.011 0.78 10.4 0.5 1 23 505 527 505 527 0.96 5 17 0.00014 0.01 16.3 0.3 1 23 535 558 535 558 0.98 6 17 0.0015 0.11 13.1 0.3 2 23 563 584 562 584 0.97 7 17 2.7 2e+02 2.9 0.1 1 19 592 610 592 612 0.90 8 17 0.00054 0.039 14.5 0.4 1 22 632 653 632 656 0.90 9 17 1.9 1.4e+02 3.4 1.5 1 21 661 681 661 682 0.89 10 17 0.0078 0.57 10.9 0.9 1 23 701 726 701 726 0.96 11 17 0.037 2.7 8.7 1.6 2 23 741 763 740 763 0.93 12 17 0.0013 0.099 13.3 0.7 3 23 770 791 768 791 0.95 13 17 0.013 0.98 10.1 0.4 2 23 795 817 794 817 0.96 14 17 1.1e-05 0.00083 19.8 1.4 1 23 823 845 823 845 0.99 15 17 0.0087 0.64 10.7 1.1 1 23 849 872 849 872 0.93 16 17 5.1e-06 0.00037 20.9 1.2 1 23 878 901 878 901 0.97 17 17 0.0024 0.18 12.5 0.8 3 23 911 933 905 933 0.91
Sequence Information
- Coding Sequence
- ATGTCGGAGAATTTGAAAACTAATAATGAAAATCGAACCGGGCCTAGCTGCCTGCATTGTGGCGTGTACAATTCAAAACAGACATTCCAGCAGATATTTGATGAAGTTGGCGAAGAAATTGAATTGGCCGCTCTATTGGCTAAATACTTTCAGATAAATGTTATGCCCGATGAGAAAAAGCCGCAACTTCTCTGTCAGGAATGCGTGAATACGCTAATACGTTTTTTTGATATTGATGAACTGCAACGGGAACAGGACGCAGCTAATGCGACTAAGAATAAAGCAACAAACCCCACCAAGATTGCGGCAATAACACCACCGTCTGCTCCACCACCGCCATTGGCTCTAGCCAAAAAAGTAGATAAGCCcgccaaaaaacaaacatcATATATAACCCGAGCATCCAATGCTGGCAGAGCTCTTATAGGCGCCAAAAATGTTGCACCAACTAAACGAGCACCAGTCAGCTCCGTGCCAGCTGCAGCACCAACTCTGCGCACTAACAAGTCCAAGCCAGTGGCCTCGACAAAGCCCAAAGAGAGTCGTGCCAAGGTGGAAGAGAAGTCTCAAAATGTCAAGGAAGTTGTGTCTGGTGAGCAGGAGCAGATTAGCGCAATGATACGTGACATATTGGACGATGAGGAGACGCCGACAGCTGAGCAATTTGTTaaggcagcagccacagtgaAGAAGCTGGAAACCCAGCAGATGCGAGACCAACTGGAGCTTGCCGTGGAGGAGTCGTTGAAGAAAGCAGAGGAGGCACTTCGgctgaaacaacaacagtccaACGAACTAGAGTTTCTGGTAGAGCGCGAAGATGGTTCCTATGACATAGATGTGGAACATTTCAAAGTGGAACAGAATTTGACACCCACGCATTCCTTCTCACAGGATGATGAGTTGCCCAGCGAAGACGACGGTTCCATTAAGGTGGAACCATTTAACTTTGTGCTGATCAAGGAAACTGATGACATTGGAGATCTGTATGAATACCTAGCGACTGTGGTGAAGACCTGCTTTGAAACCTTAACATTTGAATGGAGCATTGCTTGCAGCCATTGCTCGCTGCAAGTCAGCAGCTTTGAGGAACTCTTGACTCACATGCGGAGGCGTCATCAGCAGCCCAAGCATAACTACAAGTGCCCCATTGCGGGTTGTCAATCGCAACTGCAGAGCGTCAAATCTTTGGCCATGCACTTAGTGGTGCTGCATGCCCCAGTGGCAGACATACCCATTTATGGCAGCTGTCCGGAGTGCAGCATGAACTTCTCCAATATACTGCAGTATAATAAACACTCCTGTGCTCATGTCATCAAGAAGCGACGCGGCATGCGTCTATACTGTGAGATGTGCGGACTGGAGTTTCCCTCGTGGAAGCGtttcaactTTCATAATCAATTCCACTTGGAGCGTCACAGGCCACGCGCCTGCTTTGTCTGCAATTATGCCAACAATAACATTGATGAGCTCTTCCAGCATTTGCATTATTCCCACGAGCCCGAGGGCACATTCTTCTGTGatctCTGTGATCGACAGTTTCGTGATGCCGATGTGTTTGCGGAGCACAATAAATCCCACACGAATGTCAGCAGCACCACCTACACCTGCACCGAGTGCAATGCCAACTTTGAGACACGTGGACGACTCAATGGGCACATGCGCTCCGCCCATGGCACTGTCATCAGCTGCGAGCTGTGCACCCGGGAGTTTGGCACGGAGGCCACGTATAACGTGCACATGAAAAAGCATCTGATTATTGAGCGTGAGGTGCATGTCTGCACCAATTGCGGGCTGCTCAGCGAGAACAACGAGAAGCTAgtgGAGCATGTGGGCATTGAACAGTCGGAATGCTTTGGCTTGGATGTTTGCACGGAGCTGCTGCGTGATGCTTACATCTGTGAATATTGCTCGGCATATTTCAAGCAGAAAACTGATTTGCGTGCTCATCGCGAATCCGGTGTACACAAGGATGGCCAATTCCATTGTCTGCCATGTGGCAAGCAATTTGGTGAAATGAAACTCTATCGCCATCACATACGCAACTTTCAGCAGCAGCGAGGCGATGTGGAGCATCGCAAACTAGAGATTTGTCTGTACTACATGTGTGATTATGAGGAATGCTTTGAGTCGTACATCAATTGGAATTCgctctacacacacaaacgtcGCACACATGATGTGCACCAAAAACTGGATACAACTGCAAAGGCTGAGTGGATCTGCCAGTTCTGTCAGAAGGAATGCCGCTCGAAAATGTCGCTCTCGGTGCATGTGGCTCGCAGTCATAATAATAATAATGTAATCTGTAAGGTGTGCAATGCATCGTACAAGAACGAGCAGGCACTGCAGACACATCATCGCTACTGGCATGAGCCCATGGAGTGCAATCTGTGCCTGAAGATACTCAAGAATCAGCGCAACTACGACACACACATGAATGTGGTGCACTCCAACAGTCAGCGCTACAAATGTGGCGTTTGTGAGAAGGGATTCTATCACAAGAGCGAAATGGAAGCGCATCAACGACTGCATTCTCAACTCTTTACTTGCGAACAGTGCAGTTTCACCACCAGAAACAAGAAATCGCTGTCGGTGCATGTGCTGGGACAACACTACAAGCGCTTTGCCTTTGAGTGCAAACAGTGTGATAAGCGCTTCGGTCGTCGTCAGGGCTTAACCAGTCACATGCAGCGGGCACATGGCTCCAAGTATGTGTGCCGAAACTTCTGTGATATTGGCTGCAGCAAAGTGTTTTCCACCATCTCCAGGCTGAATGTGCATGCACGTAAGGCGCATGGTGTCAGTGTTATGGTCCTTATGGATAAATTGGACAGAACTACCGGCGAGGAGGATGTATTGGAGGTGTCCTTAGAGTTGGATGAAGAAGAGCTGCCTGATGAGGGTCCATCCACATCAAAAAAAAGTTCCATACGCCTCAGTGATGATACACAAATTGAGTTTATCACTGGCGAAGAGAATGATGAGAGCGTAATTACATCGGAGAGCTATGAAGAGACAGCCCCGCCCAAGCCGAAGAAACTGAAGCACAAATGA
- Protein Sequence
- MSENLKTNNENRTGPSCLHCGVYNSKQTFQQIFDEVGEEIELAALLAKYFQINVMPDEKKPQLLCQECVNTLIRFFDIDELQREQDAANATKNKATNPTKIAAITPPSAPPPPLALAKKVDKPAKKQTSYITRASNAGRALIGAKNVAPTKRAPVSSVPAAAPTLRTNKSKPVASTKPKESRAKVEEKSQNVKEVVSGEQEQISAMIRDILDDEETPTAEQFVKAAATVKKLETQQMRDQLELAVEESLKKAEEALRLKQQQSNELEFLVEREDGSYDIDVEHFKVEQNLTPTHSFSQDDELPSEDDGSIKVEPFNFVLIKETDDIGDLYEYLATVVKTCFETLTFEWSIACSHCSLQVSSFEELLTHMRRRHQQPKHNYKCPIAGCQSQLQSVKSLAMHLVVLHAPVADIPIYGSCPECSMNFSNILQYNKHSCAHVIKKRRGMRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCNYANNNIDELFQHLHYSHEPEGTFFCDLCDRQFRDADVFAEHNKSHTNVSSTTYTCTECNANFETRGRLNGHMRSAHGTVISCELCTREFGTEATYNVHMKKHLIIEREVHVCTNCGLLSENNEKLVEHVGIEQSECFGLDVCTELLRDAYICEYCSAYFKQKTDLRAHRESGVHKDGQFHCLPCGKQFGEMKLYRHHIRNFQQQRGDVEHRKLEICLYYMCDYEECFESYINWNSLYTHKRRTHDVHQKLDTTAKAEWICQFCQKECRSKMSLSVHVARSHNNNNVICKVCNASYKNEQALQTHHRYWHEPMECNLCLKILKNQRNYDTHMNVVHSNSQRYKCGVCEKGFYHKSEMEAHQRLHSQLFTCEQCSFTTRNKKSLSVHVLGQHYKRFAFECKQCDKRFGRRQGLTSHMQRAHGSKYVCRNFCDIGCSKVFSTISRLNVHARKAHGVSVMVLMDKLDRTTGEEDVLEVSLELDEEELPDEGPSTSKKSSIRLSDDTQIEFITGEENDESVITSESYEETAPPKPKKLKHK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -