Basic Information

Insect: Liodrosophila aerea
Gene Symbol: -
Assembly: GCA_035045005.1
Location: JAWNNL010000158.1:91893-94359[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.074 5.4 7.8 2.3 1 23 258 280 258 280 0.99

2 11 8.8e-06 0.00064 20.2 0.3 1 23 286 308 286 308 0.99

3 11 0.00019 0.014 15.9 2.9 1 23 314 337 314 337 0.97

4 11 0.36 27 5.6 3.8 1 20 343 362 343 365 0.95

5 11 0.0089 0.65 10.7 1.7 1 23 371 393 371 393 0.97

6 11 7.2e-05 0.0053 17.3 1.1 1 23 399 421 399 421 0.99

7 11 0.00015 0.011 16.3 2.2 1 23 429 452 429 452 0.96

8 11 0.0005 0.037 14.6 0.2 3 23 460 480 458 480 0.97

9 11 0.0017 0.12 13.0 1.3 1 23 486 508 486 508 0.98

10 11 2.3e-05 0.0017 18.8 0.9 1 23 514 537 514 537 0.97

11 11 5.7e-07 4.2e-05 23.9 2.6 1 23 551 573 551 573 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.074	5.4	7.8	2.3	1	23	258	280	258	280	0.99
2	11	8.8e-06	0.00064	20.2	0.3	1	23	286	308	286	308	0.99
3	11	0.00019	0.014	15.9	2.9	1	23	314	337	314	337	0.97
4	11	0.36	27	5.6	3.8	1	20	343	362	343	365	0.95
5	11	0.0089	0.65	10.7	1.7	1	23	371	393	371	393	0.97
6	11	7.2e-05	0.0053	17.3	1.1	1	23	399	421	399	421	0.99
7	11	0.00015	0.011	16.3	2.2	1	23	429	452	429	452	0.96
8	11	0.0005	0.037	14.6	0.2	3	23	460	480	458	480	0.97
9	11	0.0017	0.12	13.0	1.3	1	23	486	508	486	508	0.98
10	11	2.3e-05	0.0017	18.8	0.9	1	23	514	537	514	537	0.97
11	11	5.7e-07	4.2e-05	23.9	2.6	1	23	551	573	551	573	0.98

Sequence Information

Coding Sequence: ATGCCGAAGAAGTCGCGAGACACCGAATCCGAGGATTTGCAGTCATTTCTCAGGAATTTTCACAAGGAAATCGAGGATGGCAGTGGTGACGCTAAAAATACCAAGCCAAAAAATGCCAGCAAGCAGCATgttaaagaagaagaagatgaagaagtGGAGGAAGATGAGGACGACGATGATAAGTATTTCATTGATGATGAAGGCAATTGCTACATCAAGACCACTccaaaaaagcaacaacaacttaaaaAGAAACTCAAACAAACTGCGGCCGTGCCAGCTGCACCAATCACGGTGCGCAGCGCCCGTGGAGGCAGCAATGCAACAGCGCCTAAAGCTATCAGCTTACGCCCAGCTAAACAGAAATCGGATCTAAAGTCGCCGAAAGAAGTTAATATACGACCTGCGCCCCCAAAGCGCACATCAGCTGCAGTCAGCCCACCCAAGCCACAATTGCGTTCAGCAAACACACGGAACACAACGAAAGCCAGCACAAAGCCAGCTGTCACCAAAGTTGTTGTGGAGAAAGTGGAGATGCTCGAGGAGTATGTGGATGATCCGGACATTTTAAGCGATGTTGATGACCTCATCGAGAACACATTGAATGAGGGTGCTGCGGATGGTACAACAGCAAGCAGAGACAATCAATCGGACGACGAGGTGTACAAGTTCGAGGAAAGTGCGAACATGTCCGTCAAGCTGGATGCGGATTACGTGGTGTCTGGCAAACAGTACAAGCTGAAAACGGTGTCCGCTTCATCCCCATCGAAATACACCTGCTCGCAATGCAGCTATGAGACGAACAAGAAGTTTCTTATCTCACGTCATGTTCGCTCCCATGACATGGAGTTCTCATTCAAATGCTCGATCTGTGAGCGCGGCTTCAAGTCGAACGTAGGATTGGTGAATCATCTGAACACGCACATGGGCAACAAACCGCACAAGTGCAAACAGTGCGAGAGTGCCTTTACCACCAGTGGAGAACTGATACGCCACACACGCTACAAGCACACTAAAGAGAAGCCGCACAAGTGCACGGAGTGCAGCTACGCCAGCGTGGAGCTCACCAAGCTGCGTCGTCACATGACCTGCCACACGGGCGAGCGCCCGTACCAATGCCCACACTGCACCTACGCCTCGCAGGATATGTTCAAGCTGAAGCGTCACCTGGTCATACACACCGGGGAGAAGAAGTACCAATGCGATATCTGCTTGTCGCGCTTCACCCAATCTAATTCACTGAAGGCACACAAGCGCATCCATAGTGTGGTGGACAAGCCAGTCTTTCAGTGCACTCAGTGCCCCACAACATGTGGCCGTAAGGCGGATTTGCGCACACACATGAGCAATATGCATACGCCGGATAAACCAATCGCCTGTAAGCGCTGCGGCCAGGTGCTGCCCGATCGCTATCAGTACAAGCTGCACATTAAGACCCATCAGGGCGAGAAATGCTATCGCTGTACTCTATGCAGCTATGCGTCTGTGTCCCAGCGCCATCTGGACTCGCACATGTTGATACACACGGATTCCAAGCCATTTACATGCGATCTATGCCCGCAGGCATTCCGACAGCGGCAGCTATTGCGCCGCCACAAGAATGTGATGCATAACGATGACTATAAGCCTCCCGAGCCACGTGATAAGTTGCACACATGTCCCAGCTGCCCGCGTGTCTTCACCCACAAGGGCAACCTAATGCGCCACATGGAGATGCACGATGATACGCTGAATGCGCGCGAGCAGAAGTTGAAGCTCAAAATGGGCCGAAATGTGCGCCTGCAGATGGATGGCAGCACTGTTACCTTGCTTAATGGCGCCGACATAAAGGCTCTGGGTGATTCCCTGGATGCAGACGAGCACGGCTACGAGTTGCAAGAAGTAGACGATGACGAAGACTTGACCAGTGATCCCGTTGTGTTAAGCACGGCTAAACCGAAAACGAGCAATAGGATCACACTCAAGGAACGCCAAGAAGCTCGTTCCAAAGGCAGTAAGCCCGTCATTATCAATCGCCAACTGAAGGTATCACGCCCAAATAGGGAGCTGACCACCCAATCAGGCACGTTTCGCATTAAAGAGGAGCCGGAAGCCAACGAATTTACCGTGGAGTTGGAGGGCGATGATGAGCAGTTTATGGTCGTGCAACTGGTCAACGACGAGAACGAAGTTGTGGTCAAACGCGAATCAAAAACGAATGTGAATGCCAACAACTGTTTTGGCTTCGAGGAGGATGTTGATGCTGACTATGAGGAGGAGTACGCTGAGCCTTCAGTGGAAGTGGATGGCGCATCGCAAGAGTTTCTTCAGCTGATGGATATGATTGAGCAGGACGGATAA
Protein Sequence: MPKKSRDTESEDLQSFLRNFHKEIEDGSGDAKNTKPKNASKQHVKEEEDEEVEEDEDDDDKYFIDDEGNCYIKTTPKKQQQLKKKLKQTAAVPAAPITVRSARGGSNATAPKAISLRPAKQKSDLKSPKEVNIRPAPPKRTSAAVSPPKPQLRSANTRNTTKASTKPAVTKVVVEKVEMLEEYVDDPDILSDVDDLIENTLNEGAADGTTASRDNQSDDEVYKFEESANMSVKLDADYVVSGKQYKLKTVSASSPSKYTCSQCSYETNKKFLISRHVRSHDMEFSFKCSICERGFKSNVGLVNHLNTHMGNKPHKCKQCESAFTTSGELIRHTRYKHTKEKPHKCTECSYASVELTKLRRHMTCHTGERPYQCPHCTYASQDMFKLKRHLVIHTGEKKYQCDICLSRFTQSNSLKAHKRIHSVVDKPVFQCTQCPTTCGRKADLRTHMSNMHTPDKPIACKRCGQVLPDRYQYKLHIKTHQGEKCYRCTLCSYASVSQRHLDSHMLIHTDSKPFTCDLCPQAFRQRQLLRRHKNVMHNDDYKPPEPRDKLHTCPSCPRVFTHKGNLMRHMEMHDDTLNAREQKLKLKMGRNVRLQMDGSTVTLLNGADIKALGDSLDADEHGYELQEVDDDEDLTSDPVVLSTAKPKTSNRITLKERQEARSKGSKPVIINRQLKVSRPNRELTTQSGTFRIKEEPEANEFTVELEGDDEQFMVVQLVNDENEVVVKRESKTNVNANNCFGFEEDVDADYEEEYAEPSVEVDGASQEFLQLMDMIEQDG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -