Laer016939.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Liodrosophila aerea
Gene Symbol
hang
Assembly
GCA_035045005.1
Location
JAWNNL010001408.1:246323-266670[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.38 28 5.6 1.0 3 23 551 572 550 572 0.93
2 19 1.1 80 4.1 3.2 3 22 679 698 677 698 0.89
3 19 0.00081 0.06 14.0 3.3 1 22 800 821 800 823 0.90
4 19 0.094 6.9 7.5 0.1 2 21 835 854 834 855 0.93
5 19 0.00094 0.069 13.8 0.2 2 23 988 1010 987 1010 0.95
6 19 0.0027 0.2 12.3 0.1 1 23 1018 1041 1018 1041 0.96
7 19 2.2e-05 0.0016 18.9 0.1 2 23 1128 1149 1127 1149 0.97
8 19 0.00039 0.028 15.0 2.9 2 23 1262 1284 1261 1284 0.97
9 19 0.03 2.2 9.0 0.2 2 23 1293 1315 1292 1315 0.95
10 19 0.0079 0.58 10.8 0.9 1 23 1328 1351 1328 1351 0.97
11 19 0.00017 0.012 16.1 1.1 1 23 1385 1407 1385 1407 0.99
12 19 0.0026 0.19 12.4 0.9 1 23 1415 1438 1415 1438 0.96
13 19 0.092 6.7 7.5 0.4 2 19 1446 1463 1446 1464 0.94
14 19 9.7e-05 0.0072 16.9 0.4 3 23 1566 1586 1565 1586 0.98
15 19 0.0014 0.1 13.2 0.1 1 23 1621 1643 1621 1643 0.97
16 19 8.4e-05 0.0061 17.1 0.6 2 23 1732 1754 1731 1754 0.93
17 19 1.1 81 4.1 0.1 2 20 1774 1792 1773 1794 0.91
18 19 0.0087 0.64 10.7 0.3 3 23 1809 1829 1809 1829 0.98
19 19 9.1e-05 0.0067 16.9 2.1 1 23 2289 2311 2289 2311 0.99

Sequence Information

Coding Sequence
ATGTGCGACGCtgccgcaacaacaatagcagcagcagcaacagcgtctAGTGGCGGTGGAGGAGGCGGCGGCGCTGCAGGAAGCAGTGACAACTTGACCGCAATGGAAGAACAGAATCAACGCACCCGACAGAGTTGTTGTCGCCTCTGCATTGCGCCCGCCAGCGAGTGCATTTCCATCATTAACAGTTATGCAGCCGATAAGGAGCCGCTGGCCACTAAAATACATAACTGCGTAAATATCAAGATCACAGCATTGGATCGTCTGTCGCTGCACATCTGCCATGCCTGCATCAGCTATTTGAACTCGTGGCAGAGCTTCAAGAACCGCTGCCTCAGCTCACAGTCGAAGCAGAGACAATGGCTGGAGTCGGACCGAAGCAAGCAGCAGACGCTATTGGGCTACTTGGATTTGAACAGAGCCGAGAACGGTAGCTCTGGTCttgatcagcagcagcagcagcagcaacagcagcaatctgAATTGAAAAGCGattcggcagcagcagcagcagcagccgcagcagcagtagcagcagcagaaaaggTGTCCGCCAACATATTGGATGGTATACCCTCGTTGAAGAAGCGCAAATCGTTAACAGTCTATGTGAGTCcaaagcaacagctacaacagctgcaacaacatcaacagcaacaacaacagcaatcagcCAAAACGACGAGCGCGGCGGCGGAGACGCAGCAGCAAACGTTGCAGACCCTTTTATTGCAGGTGCCCTCGACAacattggcaacaacaacggcaatgCAGCAGCGCaaatatcagcagcagcagcaacgtggcaggcagcaacatcatcactatcaacagcaacaacaacatcagcaacagcagcattatcagcaacaacatcatcagcatcagcatcgacAGCGACGCATGCGTCAGCCAaagcgtcagcagcagcaacagcagcaacaactacagcaacaacagccagcgtcagcaacaattgcaactgcaactgcaactgcaacagctgccgccGTGCAACGCATGGCCAAGTTTAAGCCGAAAGTGTTTTTGCCACTGGATATAGCTGTGCCACCATTGCCGCCACTGCCAATGCCGCTGCCCGTGGCACCAACTGCTGTTgaggcattgccattgccattgtcgttgtcgttgccaATTGATTTCAGCCAGCCTCTGACTCtgaatcccaatcccaatcccaatgccAATCTCAATCCCAATTCGAATTCATCTCAGAATCCGAATCAGAGATACAGCAGCGTTTTGccactgccgccgccgccgccgccgccgcttcTGCCACCGGTTGCAACAATGGctagcagcagcgcagcagcagcagcaacagttgctgctgccacggtCACGACTCCGTTGCTCATGCCGCCTCTGCCTGCGGTCCCCATCAAAGATGAGCCCCTGGACGATACGGACGATGACTTTCAGATGAAGTGCATTGACGAGTCGGACGACATGATGGATCCGACAATGTTCCTGGAGCGTTCCGAGCACGAGGGCGACGTGCCATTGATGGCCGCGGACTATGATTACACGGCACAGCATGGCgtgccagcagctgttgctgccgcatCCTTGCCAGCCAGCGCTGTGGCAAATGTGGCTGCCGCTGGCGACTCTAAGGTGGCCAGCTGCCGCGCTTGCAGTCTGCAGTTCTCGACGCGTGCCAATGCGAGACGTCATGAGCGGAATCTGCATCCGAATCTGTTTCAATTGTCGACCGATTCGCCCAATAACACGCCTATAACCAAACCGACGCCAGCTCTGGCCGCCGCACTGGAGATACAGCgtgcagctgccgctgctgctgccacagcggAGGCAACCAAGGCGGCGGCTGGTGGCAACATATCCACACAGAAGTATCGCCAGGTGGTGATGAATACGTTCATCAAGTGCGAGAATGGCGGATACGATTACGAGAATCCGGAACAGTATCAGCCGCTGCTGACGCGCGACAAGATCGAGTTCATACAGGACAACAACGAGTTTCTGGAGCAGTACCAGACGATGACGTGTCGCTGCTGCAACAAGTACTTCAATACCTACAAGAATTTCATGGCGCACGTGCGCAAGAAGTATCCACTGCTGCCGCGCAATCTCTGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTCTTCATCTCACATCTTAAGAAGCGCAACTGCATCAATCTGTTTCGTGTGTTGCATGCGCTGCGGGGCAAACAGTCCGGCACAGATCAGCATTCAGCGGGgggagctgcagctggagctggagcatcAGTTGGCGCTGTCTCAGCATCCGCATCGGCGGCAACCACACCGCATGATACCTCATCGTGTTCGGAGCGGCCGGAGAAGCTGCGCGCCAAGGAGCTGCTGGTGAACAAGCTGTACGAATGCAAGCTCTGCCCCAAGGGATTCCGCACCAAGCACGAGTTCCGCACCCACGTCTACGACAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGCCTGGACTTTGCCGATCCGGTGGATCGTCGCCGACATTACAATAACATGGACTGCATTGTGCGGCTGCGCTGCATGACGTGCGATGCCAAGCTGGAGACGCACCAGCGCTTCCTCGATCACGTGTATCATGATCATCTGGGCGTGGCCAGCAGCGATAATACGTCCACAGCGAACAGTGGCGGTGTTATGGATCATTCGCCTGGCAAGCGCAGCCTGCTGGGCGCACTGGGGATTGGGGTCAGTCAGGCCTCGTCCAATGATGAATCacgcggcagcagcaacaataacaatccaAATGCTCCACTTACCTCAACGCCCAAGCCAGGTGCAACGGGTGTGGCAGGAGTAtctggagcaacagcagccggaGGAGCAGCATCTTCATCCGGTGGCGGTAATCGTGATGCACCTAAATCACAGTATTTCTCGCGCATGCCACAAGTGTGCCCCATCTGCGGCCAGCAgtacaacaactataacaatgTGCTGCGCCACATGGAATCGAAGCATCCCAACAAGTTGCCCGAGACCTACAAGTGCGTCCGCTGTGGACTGGGCTATCCGCGCATCTCCTACCTGCGGGAGCACATGATCAACGTGCACGGCGTCGATAAGAATCGCCATTCTGGCGGATTCGAGTACATTGTGAACGCGGATGCTGTCAAGTTGGCGGATGGTAGCACACCCAACGTGTATACCGGACGATATGATTATGTGATGAAGGATCTGATGTCCATAACAAATGGTGGGACACTCGatgacgatgaggatgagcCTGCGGGCAGTGTGGCGAAGAAGATGCGTCTCGatgacagcagcaataatagcAGCATTAACACGAGCATTGCCAATCAGCAGAAGGAGTGCCCCATCTGCAACGCGGTGTTCAGCAACAATATCGGTCTGTCAAACCACATGCGATCCCACTACACCGCCTCATCGACGGCAGCCACAAATGCAGCGTTGGCTGCTGCCAATCGCATGACACCCAAATCACTGACCATAACGGCAACATCGTCGCCATTGGATGTGGCCAATACATCGAGCACTGCTGGAGGCggaggcagtggcagcagcagtagtagcaccACCACCATAACCGTAACACCAGCCACAACAAAGGCAGCCGCAGCTGGCGAGAATGCCGGAGGAGCAGCAACTGGGGGCAGCTTACCACCAGCGATGGTTCATCAGACGCCGCAGGAGCAGGCGGTGTTCCGTCGCAGTTTGGACCAGGCGGCCGATCGTCGCTTCCGTCGAATGCGTTGCCGCATCTGCCAGCGTCGCTTCAGCTCAAAGAAGTCGTATCGCTATCACATGCTCACCGATCATCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCGGAGTTTGCCTACGAGAAGGGGTTGAAGGTGCATCTGTTCAAGGTGCACGGACGTGCCATCAAGGACGAGATGATTGTCAAGCAGTTCGAGTGCGATGTCTGCTCCACGGTCTACAGCTCTGAGCTGGAGTTGCATCAGCACAAGCGTAGTGTTCACAAATCCCAAGCCAGCGCGCCGAAGTCATCAAACAAATCCCTAACCTCAACATCTGCCGACGTGGCGGATGTCTCTGCTGGCACATTGCCGCTGTATTGGTATCAGTGCAAGTACTGTCCATCCAATTTCAACACCAACAAGAAGCTTGCCATCCACATCAATTCGCACGACGAGTTCGATTCGAATGATTACTCCTGCAAGGATTGCGGCAATGTCTATAGTGGACGCAAGAGTCTCTGGGTGCATCGGTATAAGAAACATCCGCAGGTTCCGGATCCGGCCGAGTGTACGCTGTGCCGCAAAATGTTCTTTGACCGTCAAATGCTGGAGAATCACACGCCCACCTGCAATCGCAAGCCTATCACAGCGACCGGGGCACATCAGcaggatcagcagcagcagcagcaacagcatcagcgtAGCATCTTTAAGCACAAAACTGgcgacgatgatgacgacgaggAGGATGATAATCAGCAAATAATGCTGCTTGACGATGCCGATGGTGGCACAGAcggagcaggaggagcagcagcagcagccggtgGTGGAGCTACTGGCAGTGATAGCAATGGTGGCACAAGCACAACAAAGAACACCATTAACACCAGTTCATTGAAGATACGCATACCGGAGGTGGCATGCACCATCTGTGGTGCACGCTTCACCGATCAGGAGATGTTTAGCAAGCACATACAGAAGCACGAACAGGAGCTCTATGTGGACAATCCGCTGGCTGCCATGTTCGACGATGGCCCAGCCGATGCCGGCCAATTCCAGGTGGAGCGCCAGAACGAGAATGGCGAATATGCGTGCGATCTGTGCACCAAGACGTTCCCCCAGGTGATCGCACTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCCATCATCGACGGCGAAGCGACAATGctgaacaacagcagcagcaacagcaacaacaacaactcgatgCTGCATCTGCGCGAGCTGCATGCGGTGGGTCTGATGCCCAATCAGCAGCACcagaagcagctgcagctgaacaacaacaacaacatcagcaacaacagcagcagcagcagcaacaacaacaacaacaacagcagcaacagaagcaaaTCGATGAAGCGGAAACGTGAACTGAAATGTGAATACTGCCCCTCCACcttcatcagcaacaacaacctgcGTCGCCACATGTACGAGCTGCACAAGCACGAGGTGAGTAATCTGCCGGAGCCACCAGTGATCGAGGTGGATGAGCCGCTCAGCTGTCGCCGCTGTGACCTGCGCTTCGACACCAAGGAGCTGTGGATCGAGCATAAGCTTGCCGATGCCAAGGTGGTGCGTCCATTCTGCCCCTTTCAATGGGGCTGTGATCTCTGTGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATCAATCACATAAACAATCATCTCAAAGAGGAGCTGATTGTGCCAGTGGCAACCaaagcaacagcggcagcagcagtggtgAACCACAAGacaccagcagcagtggcggcatcagcaacaacagcagcagcagcagcaccatctAAGCCTGCAGCTACGCCAGCAAAGACAAGCGCAActgcaggagcaggagcagcaccAACACTAGCAAAGGCTAAGCTCAAGACAGAGGTGAAGACGGAGCGGCAGCTGCATGATAAGGTcgaagaggaggaggtggCGAAGGGGGTGCCGGCGTTAGAGGTGGACGATAGTGATATGGATGAGAATAGCGATAGTGATGACAACGATGAGGAGAGCAGCACAGCTGAAGATgaaggggaggaggaggaggatgatgatgctgatgatgacgatgatgatgatgacgacgatgatgaggatgatgaggaGGACGACAATGAGGATgatgtgcaacaacaacagcagcacaacaacagaagcaacaaTATTGTCGACGATGATGATCTCATCGAGGAGGTCATTGAAGATGACGACATTGTCGAGGAGCTGGACGACGATGAtggcaacagccacagccacagcaacagcaagcagcAAACTCGACGCCTAAATTTTGAGTACAGCAGCAAGCTGAATGGAAAAGCGAAAGCCAAGACAGTGCACAGCtctgaggatgatgatgatgttgatgaagATGATGTTGAGGCAGTCGAAGGGGCTGCTGGTGTAGGTGTGAGTGTGGGCGAGGGTGTGCCCATGACAATTGATGATATTATCGAAGAAGATCATGGCGAGGACGAAGAagatgacgacgacgaggatgatgatgatgtggttGACGTCAGTGGTGGCACACACGTTGTTGCCGATAATGATGAGGATGAAGACATGGAGGACGTTGACGaggacgatgacgacgacgacggcgacgatgatgatgacgacgatgacgatgacgatgatgatgaggatgatgacaCGGACGATGACAacgacaatgacaacaacaatgccaacgcTGATAATGATGTGGAAGACGATGACGTCGACGAAGATGATGtgattgatgatgatgatgatgaagacgtggaacggcagcaacagccacagcgacagcgacagcagccgGCGAACATCAGCAATGGTGACGCCAtggatgtcgatgtcgatgctgatgctgatgctgaagTTGAtgctgccattggcattgattCGTCATCATCAGCGAGCGAATcgtcgacgacgacggcggcaacaacaaccacggcCAATTCACATTCAACTGGTGAGCGGCGTAAAAGTCATAAGAAAGTAGCTGCATCAGCTGCAGCGGCGGCACCTGGCGCTGCCGCTGATCAGTCTAATAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCTACTGCAGACACATATTAAATCACATTTCCTCAATGGGCCTGCGTTGAGCAAGACCACCAGCGTTGTCAAcgccagcggcagcggcagtggcagtgccagTGGCAGAGCCAGTGTAaacggcagtggcagcagccgtagcagcaacagcagcagtaggagcaacagcaacaataacagcaataaaaccaaaacaaataagTCCGCCTtgaatgcaacagcagcagcagcagcagcagcagcaacgacggcagcagaggcagcgccAGATGCTGCAACGGGCTTGAACTGA
Protein Sequence
MCDAAATTIAAAATASSGGGGGGGAAGSSDNLTAMEEQNQRTRQSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITALDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLESDRSKQQTLLGYLDLNRAENGSSGLDQQQQQQQQQQSELKSDSAAAAAAAAAAVAAAEKVSANILDGIPSLKKRKSLTVYVSPKQQLQQLQQHQQQQQQQSAKTTSAAAETQQQTLQTLLLQVPSTTLATTTAMQQRKYQQQQQRGRQQHHHYQQQQQHQQQQHYQQQHHQHQHRQRRMRQPKRQQQQQQQQLQQQQPASATIATATATATAAAVQRMAKFKPKVFLPLDIAVPPLPPLPMPLPVAPTAVEALPLPLSLSLPIDFSQPLTLNPNPNPNANLNPNSNSSQNPNQRYSSVLPLPPPPPPPLLPPVATMASSSAAAAATVAAATVTTPLLMPPLPAVPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMAADYDYTAQHGVPAAVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISTQKYRQVVMNTFIKCENGGYDYENPEQYQPLLTRDKIEFIQDNNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLFRVLHALRGKQSGTDQHSAGGAAAGAGASVGAVSASASAATTPHDTSSCSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYHDHLGVASSDNTSTANSGGVMDHSPGKRSLLGALGIGVSQASSNDESRGSSNNNNPNAPLTSTPKPGATGVAGVSGATAAGGAASSSGGGNRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEDEPAGSVAKKMRLDDSSNNSSINTSIANQQKECPICNAVFSNNIGLSNHMRSHYTASSTAATNAALAAANRMTPKSLTITATSSPLDVANTSSTAGGGGSGSSSSSTTTITVTPATTKAAAAGENAGGAATGGSLPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDVCSTVYSSELELHQHKRSVHKSQASAPKSSNKSLTSTSADVADVSAGTLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQHQRSIFKHKTGDDDDDEEDDNQQIMLLDDADGGTDGAGGAAAAAGGGATGSDSNGGTSTTKNTINTSSLKIRIPEVACTICGARFTDQEMFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCTKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATMLNNSSSNSNNNNSMLHLRELHAVGLMPNQQHQKQLQLNNNNNISNNSSSSSNNNNNNSSNRSKSMKRKRELKCEYCPSTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLSCRRCDLRFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEELIVPVATKATAAAAVVNHKTPAAVAASATTAAAAAPSKPAATPAKTSATAGAGAAPTLAKAKLKTEVKTERQLHDKVEEEEVAKGVPALEVDDSDMDENSDSDDNDEESSTAEDEGEEEEDDDADDDDDDDDDDDEDDEEDDNEDDVQQQQQHNNRSNNIVDDDDLIEEVIEDDDIVEELDDDDGNSHSHSNSKQQTRRLNFEYSSKLNGKAKAKTVHSSEDDDDVDEDDVEAVEGAAGVGVSVGEGVPMTIDDIIEEDHGEDEEDDDDEDDDDVVDVSGGTHVVADNDEDEDMEDVDEDDDDDDGDDDDDDDDDDDDDEDDDTDDDNDNDNNNANADNDVEDDDVDEDDVIDDDDDEDVERQQQPQRQRQQPANISNGDAMDVDVDADADAEVDAAIGIDSSSSASESSTTTAATTTTANSHSTGERRKSHKKVAASAAAAAPGAAADQSNNSSYTCDLCQLCFDSQELLQTHIKSHFLNGPALSKTTSVVNASGSGSGSASGRASVNGSGSSRSSNSSSRSNSNNNSNKTKTNKSALNATAAAAAAAATTAAEAAPDAATGLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-