Laer008072.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Liodrosophila aerea
Gene Symbol
su(Hw)
Assembly
GCA_035045005.1
Location
JAWNNL010000782.1:107071-110172[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0007 0.052 14.2 2.2 1 20 216 235 216 237 0.94
2 12 2.8e-06 0.0002 21.7 0.4 3 23 288 309 286 309 0.93
3 12 0.013 0.94 10.2 0.1 1 23 315 337 315 337 0.97
4 12 7.5e-07 5.5e-05 23.5 2.5 1 21 344 364 344 365 0.95
5 12 3.2e-06 0.00024 21.5 0.6 2 23 377 398 376 398 0.96
6 12 0.0001 0.0076 16.8 5.3 1 23 409 431 409 431 0.99
7 12 8.1e-05 0.0059 17.1 0.9 1 23 437 459 437 459 0.97
8 12 1.6e-05 0.0012 19.3 0.8 1 23 465 487 465 487 0.99
9 12 1.5e-06 0.00011 22.6 3.0 1 23 493 515 493 515 0.98
10 12 0.0011 0.078 13.6 1.5 1 23 519 541 519 541 0.97
11 12 0.0014 0.1 13.2 0.2 3 20 551 568 549 573 0.93
12 12 2.2e-05 0.0016 18.9 0.3 3 23 593 614 591 614 0.97

Sequence Information

Coding Sequence
ATGACGGACACCGCGCCGGCGAAGTCCGCTTCAGGAGGTACAGTGATCAAAATATTGGATGTCTCTCAACTCACGGCACCGAAAGACAAACGTCCTGGCACGCGCATGAAACTGCTCAACGATCTGCAGGCCACACGAGGCAAGCCCGTAAAACAGGAGAAACGCGCcagcattaaaataatcaacaacaataatgagACCACAGTAGCGACTTCCAAACCGGATAGGCGCTCCGCTGCCAAGAATTCCATCAGTCCCGCTGGAGCTGTGAAAATCTTGAACGAAAAGCGTGCTGCCGCCACAACCCCGGCAAGCACAACTCCGGAGTCAAGCAAGATCAAGACAACGCCGAACAAAAGGAAGAAAATGGATCACTACGTGCTGCAGGCCATAAAGAGcgagaacagcaacaagctgGATAAAACGTCCACTATCACTGTGGAGGATGATGATACCATTGACTTTATACTCGCCGACGATGAGGTCGAGCTGGGTCCAGCTAAATCGAACGATGCCGAGTTCGTTGTCTCCAGCGTGGAGGATGAAGAGGACgaggacgatgatgacgagGACGAAGAGCCCTCAGGCGATGCTAAGACCAAGACCAAACAGACCAATAATGGCGAATTTAAGGAAATGGTGGAgcatgtgtgtggcaaatgctACAAGACATTCCGACGCATCAAAAGTCTGAAGAAGCATTTGGAATTCTGTCGCTACGACAGTGGCTATCATCTGCGCAAGGCAGACATGCTGAAGAATCTGGAGAAGATCGAGAAGGATGCAGTGTTTATGGAGAAGAAGGACATATGCTTCTGCTGCAGCGAGAGCTACGATACCTTCCATCTGGGCCACATTAACTGCCCGGATTGTCCCAAGTCGTTCAAGACGCAGACGAGCTATGAGCGCCACATCTTTATAACACACTCGGAATTTAATGATTACCCCTGCTCCATTTGCAATGCCAAACTGCGCAGCGCCGCTCTGCTCAATTTGcacgagcagcagcatcagtcgCGTGGCAAGCCCTTTGCCTGCAAGATCTGCGGCAAGGACTTTACGCGCTCGTACCATCTGAAGCGCCACCAGAAGTACTCCTCGTGCTCGGCCAATGTGAATGACACCATGAGCTGTAAGGTGTGCGATCGCGTCTTCTATCGCCTGGATAATCTGCGTGCGCATCTCAAGCAGCACCTGGGAACCCAGGTGGTAAAGAAGCCGGAGTACATGTGCCATGTGTGCAAGAACTGCTTCTACAGTCTCTCCACGCTCAACATACACATACGCACTCACACCGGAGAGAAGCCCTTCGATTGCGATCTCTGCGACAAGAAGTTTTCCGCTTTGGTGGCTCTGAAGAAGCATCGACGGTATCACACGGGCGAGAAACCCTACACCTGCACAGTGTGTAGCCAATCGTTTGCTGTTAAGGAGGTGCTGAACCGCCACATGAAGCGTCACACGGGTGAGCGGCCACACAAATGCAACGAGTGCGGCAAGAGTTTCATCCAGGCCACACAGCTGCGCACGCATTCCAAGACGCATCTGCGTCCCTACTCCTGCACAGAGTGCTCGGACAAGTTCAAAACGGAGAAACAACTCGAACGCCACGTCAAGGATCATTCGCGTCAGAAGCGTCCCTCCTTTGGCTGCCAGAAGTGCACGCGTACCTTCCGCACCAGCGCCCTGCTCAAGGAGCACGTTGATGCCGGCGTTCATTCGCCTGTAAAATCCACACGGACTAAGCGCTCTGCTAAGACCATTGAGCGCACGGATTGCGCCATTTGCGATAAAAACTTTGAGAGCACCGAGACGCTGAGGAACCACATTCGCACAGTGCATGAATGCGATCCGGACGACATCTTCGGCACTGGCCCACCAGCCAAGCGTAGGGCCACTAAGAAGCGTGCGGCGGCGCCAGACAATTTCGTCGGAGCTGATGATGAAGCAGCGGAGGAATCGGAGGAGGAGAACGCGcaagacaaagacaaagatGATTATGTACCTGCAAATGCGTCAGCGGGTTCGCTAATATCTAGCCGAGAGGATCCCAATGGGGTGGTGGTGCAGGAGTTCATAGTCGATGAGGGCGATGGCAATACTCAAACAATTATTCTAGAGAATGATGAAATCTATACCATACTGCCTTTGGATGGTGTTGAGGGAACAAGCGCCACGcctacagctgcaacagccacGGCAGCAGTCGGCAACAACGCTGAGGAGAAGACAGAGTCCACGGAGAAAAAACAACTGTCTCCGGTGGTAAAGAAGGAGCAGCGTAAATCCCTGGCGGCCAGTTTGGCAGCTGCCATTGCGGATGATCTCGATGAGCCATTGAGCGATGAAGACTTTACCGGCGAGATGCTTACCGAAGAGGACATTAAACTGAAGGAGAACATTGCCAAGCTGATCGATATGCTGGTGGATCCACAGACCCTCAAGAAATACGGCTGGCCGAACAGCTCCGAGGAGACGGTGCTATGCAAGGTGATTGAGAACTGTGGCCACGACCTGACCAAAGGCGGCGAGAACTATGCCGAGTTGGATTACGGCAGTCGCATGCGTGAATACTGCAAACTGCTATTCACAGTCGTAATACACAATGATTCCATAAAGTCGCTGCTCAACAATTTCCCCATCGATGATGTTATCGAATATGTGCTGGGCGATGAGGATCAGGACCAGGAGCAGGACACAGACAAGTCGGACGAGAAGATGGCCGAGAAGTCAACCGAGAAATCGGACAAAGACACCAGAGCGGGAAGCGTTGAAGCAAAAGCTTAA
Protein Sequence
MTDTAPAKSASGGTVIKILDVSQLTAPKDKRPGTRMKLLNDLQATRGKPVKQEKRASIKIINNNNETTVATSKPDRRSAAKNSISPAGAVKILNEKRAAATTPASTTPESSKIKTTPNKRKKMDHYVLQAIKSENSNKLDKTSTITVEDDDTIDFILADDEVELGPAKSNDAEFVVSSVEDEEDEDDDDEDEEPSGDAKTKTKQTNNGEFKEMVEHVCGKCYKTFRRIKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVFMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDYPCSICNAKLRSAALLNLHEQQHQSRGKPFACKICGKDFTRSYHLKRHQKYSSCSANVNDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYSCTECSDKFKTEKQLERHVKDHSRQKRPSFGCQKCTRTFRTSALLKEHVDAGVHSPVKSTRTKRSAKTIERTDCAICDKNFESTETLRNHIRTVHECDPDDIFGTGPPAKRRATKKRAAAPDNFVGADDEAAEESEEENAQDKDKDDYVPANASAGSLISSREDPNGVVVQEFIVDEGDGNTQTIILENDEIYTILPLDGVEGTSATPTAATATAAVGNNAEEKTESTEKKQLSPVVKKEQRKSLAASLAAAIADDLDEPLSDEDFTGEMLTEEDIKLKENIAKLIDMLVDPQTLKKYGWPNSSEETVLCKVIENCGHDLTKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQDQEQDTDKSDEKMAEKSTEKSDKDTRAGSVEAKA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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