Basic Information

Insect: Linnaemya vulpina
Gene Symbol: ZEB2
Assembly: GCA_963675445.1
Location: OY776277.1:105587162-105589734[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.018 2.1 10.2 0.8 1 23 324 347 324 347 0.97

2 11 0.0069 0.82 11.5 0.2 1 21 411 431 411 432 0.94

3 11 0.00018 0.021 16.5 0.3 1 23 440 462 440 462 0.98

4 11 0.0026 0.31 12.8 1.7 1 23 466 489 466 489 0.96

5 11 1.5e-05 0.0018 19.8 2.8 2 23 496 517 495 517 0.98

6 11 6.4e-08 7.7e-06 27.3 1.3 1 23 523 545 523 545 0.95

7 11 0.00012 0.015 17.0 0.7 1 23 551 573 551 573 0.99

8 11 3.1e-05 0.0037 18.9 4.7 1 23 579 601 579 601 0.99

9 11 0.0042 0.49 12.2 0.5 1 23 607 629 607 629 0.98

10 11 0.0042 0.49 12.2 4.8 1 23 635 657 635 657 0.98

11 11 0.0016 0.19 13.5 4.8 6 23 666 683 663 684 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.018	2.1	10.2	0.8	1	23	324	347	324	347	0.97
2	11	0.0069	0.82	11.5	0.2	1	21	411	431	411	432	0.94
3	11	0.00018	0.021	16.5	0.3	1	23	440	462	440	462	0.98
4	11	0.0026	0.31	12.8	1.7	1	23	466	489	466	489	0.96
5	11	1.5e-05	0.0018	19.8	2.8	2	23	496	517	495	517	0.98
6	11	6.4e-08	7.7e-06	27.3	1.3	1	23	523	545	523	545	0.95
7	11	0.00012	0.015	17.0	0.7	1	23	551	573	551	573	0.99
8	11	3.1e-05	0.0037	18.9	4.7	1	23	579	601	579	601	0.99
9	11	0.0042	0.49	12.2	0.5	1	23	607	629	607	629	0.98
10	11	0.0042	0.49	12.2	4.8	1	23	635	657	635	657	0.98
11	11	0.0016	0.19	13.5	4.8	6	23	666	683	663	684	0.93

Sequence Information

Coding Sequence: atggaTATCGACAAAATATGTAGGTGCTGTCTGGGCTTGGATATGCCACTGTTATCCATATATGATGCTGGATCGTTTGGAACAGGATGTGTAGCGGATatgttaaaacaaatttccAAGTTGATGCCTCAGCGAGGCGATAATATGCCAGAGAAAGCGTGTCTGCAATGTATAAGCGAAATAAATCGCTGCTATGTATTCAAAATGAAAtgtgaaaattcaaataaaactcttaGGCAGTTATTACCAGAAGCAGTACCTGAGCCTTTGGATTTCGTAGCAAAAAAGATTATTGAAGCATCATCAGCTGTGCAGACTGAAGACAAATCAGTAATTACGTATCCGGTACAATCTTTAAAGGAAAAGGAACCTTTAGTTAACCACGTAAGTGTTCAAACAGTTGAAGTAAAGCCATTTGTAAGTCATACAGAAGTTCAAACTGAATACGAAGTTATTAAATCTTgtgaaaacaaatacaaaagacatgatgagcatctagaagatatttttatatatgaaggaATAGAAAATTCTAGTGAAAAAAATGAGGAGGAAGAAGAATTCATGCCAGAAAGTAAACCGATGAGCAAAAGATTGCGTTTCGAAAGCAGTAAAGCAGTTGATATTGAAACGAAGGAAGAATCGCAGATAAATTCTCAACGAACAAGTGCTTATATATTACTTGAGGACTCAAACTGCTCCGCAGAAActgaaatatatacacaaaGTACAACAGACAATCAAAAGTATTCTGAATTTGATCGCTATGAATACTATGAAAATGAAGAAGATGAAATTGAAGATGATGAGCAAAAGAACTTAATATATCAGGAAAACGAAGACTCAACTGAAAATTATAAAGTAAGTACTGTTTATGAAATTGATAGCTCAGAAGGAAAAACCAAGTCTGACGAGGAAGCTGAAGCAATAATTAAACATAGGAACAATAAAAGGAAACCAAAGGGACAATATAAATGTTCAGAATGCATAATGACATTTGTAAGTACGAAGGTACTTAAGAGACACTTAGCCAAAATGCATGATATTAAAGATGATGAACTTATAATTGATTACGTACCTGATGATCCTGATGAGATGCCAAAACGTGTGGATGGTCCTTTATATAATTCTATTCTAGAATTGACATCAGAAAATGTTCCCAAACCGCAATTAATGCCACGAGAAAAACCAGCTTCTCTACCAAGTGCCGAAATATTAAcggatgttaaatatttttgcgacaATTGCCAAGCTGGATTTGCACAACGCAAAACATTGACAGCACATGTTAAACAACGAGTCTGTATgactaataattttaaaTGTAATATTTGTGAGAGTATCTTTGTCTCTGAAGAAAATTTGGAAACTCACAAACTCACACATGAAAATCCACACAAATGCCTAGAATGTGACACAGTGTGTAAAACTATTGAAGAATTAAGTGAACATATGATTAGTTCTCATAATAGAAGTGCACGGAATCAATGTCATGTCTGCAAAAAAGTTTTTACAATGAAAACATCGTTAAATGACCACTTGCGTATACATAGCGGCGAAAAACCATTCCTTTGTACAATATGTGGGAAAAGTTTTCGTCAGAACTCAAATTTGCGCCAACATTTGATACGTCATACGaatgagaaaaatttcaaatgtgacAATTGTCCCAATGCCTACGTAACTAAAGCAGAGCTATTCTCTCACAAACGAACCCATACAGGTGATCACCCATTTAAATGTGATATTTGTCAAGCTCGTTTTACCACATCCTGTTCATTGAAAAAACACGTACGCAAACATACTGGTGAAAGACCATATGCTTGCGAATTTTGTTCCAAGCGTTTTGCTGCTCTTAATGTGTTAAAAAATCATCGTCGAATACATACTGGTGAAAAACCCTTCCAATGCGCTCACTGTCCAAAAAAGTTTACCCAAAAAGGCGATTGTTTAATGCATGAGAGAACTCATATCAGTAATgatttcaagtgtttttgtgaTACAAAGTTTTCAAAGAAATCTAATTTAACTTACCATATAAAGACACATCATCCCAATTATAACGAAAAAGAACTTCAAGATATGCTAGATAAAACTATCCATTACAACGATGAAGCTGAGtatcatataataaaaagtactaataatgaaaatgataatgaGCATTTTGTAGCAATTTCGCATGAAAAAACATCTTCGAATGATAATGGTGATGAGTTGGTGGAAATTGTCTTTCAAGATGTAGGTTAA
Protein Sequence: MDIDKICRCCLGLDMPLLSIYDAGSFGTGCVADMLKQISKLMPQRGDNMPEKACLQCISEINRCYVFKMKCENSNKTLRQLLPEAVPEPLDFVAKKIIEASSAVQTEDKSVITYPVQSLKEKEPLVNHVSVQTVEVKPFVSHTEVQTEYEVIKSCENKYKRHDEHLEDIFIYEGIENSSEKNEEEEEFMPESKPMSKRLRFESSKAVDIETKEESQINSQRTSAYILLEDSNCSAETEIYTQSTTDNQKYSEFDRYEYYENEEDEIEDDEQKNLIYQENEDSTENYKVSTVYEIDSSEGKTKSDEEAEAIIKHRNNKRKPKGQYKCSECIMTFVSTKVLKRHLAKMHDIKDDELIIDYVPDDPDEMPKRVDGPLYNSILELTSENVPKPQLMPREKPASLPSAEILTDVKYFCDNCQAGFAQRKTLTAHVKQRVCMTNNFKCNICESIFVSEENLETHKLTHENPHKCLECDTVCKTIEELSEHMISSHNRSARNQCHVCKKVFTMKTSLNDHLRIHSGEKPFLCTICGKSFRQNSNLRQHLIRHTNEKNFKCDNCPNAYVTKAELFSHKRTHTGDHPFKCDICQARFTTSCSLKKHVRKHTGERPYACEFCSKRFAALNVLKNHRRIHTGEKPFQCAHCPKKFTQKGDCLMHERTHISNDFKCFCDTKFSKKSNLTYHIKTHHPNYNEKELQDMLDKTIHYNDEAEYHIIKSTNNENDNEHFVAISHEKTSSNDNGDELVEIVFQDVG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00899926;
90% Identity: -
80% Identity: -