Lvul023354.1
Basic Information
- Insect
- Linnaemya vulpina
- Gene Symbol
- ZFX_1
- Assembly
- GCA_963675445.1
- Location
- OY776279.1:15600937-15602662[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.0031 0.37 12.5 0.2 2 23 213 235 212 235 0.94 2 9 8.7e-07 0.0001 23.7 0.5 1 23 268 291 268 291 0.97 3 9 0.00091 0.11 14.2 1.9 1 23 300 322 300 322 0.96 4 9 2e-05 0.0024 19.5 0.2 1 23 330 353 330 353 0.95 5 9 1.4e-05 0.0016 20.0 0.7 2 23 360 381 359 381 0.97 6 9 0.062 7.4 8.5 0.2 2 23 390 412 389 412 0.93 7 9 1.7e-05 0.002 19.7 0.3 1 23 420 443 420 443 0.97 8 9 7.2e-07 8.6e-05 24.0 0.6 1 23 449 471 449 471 0.98 9 9 1.4e-05 0.0016 20.0 1.7 1 23 477 500 477 500 0.96
Sequence Information
- Coding Sequence
- ATGGATTGCTGTTTGTtgtgtttgaaattaaataaagatcTAATGGGATATATAGTGGCACATTCAGAGCAGTGGCAAGAGCTTGGTATAacgaaattattagaaaaacatTTCTGGCCACTGAGTAACATGCAGCCATCCTCCTGGCTTTGCTCATCTTGTTGGCAAGAGCTAAACAATTTTCACAAGTTTTATTTGAGTATAGAAGAAGCTCATATGGCCTTAGGTAGAATTAAAATTGAGGATGAGTCAAAAGAAGCCATAAGACAAATAACAGATTTTGCATATCTCGAACCAGAAATATTAATAGACCAAGCAGCAGTAGAgaacaaagaattttttgtaaaactggAAGGAGAGGAGGATGATTTAAATGATTATCCTGTAATAAGTGCGGATCCTTTGACGAAGCCATTAATAATACCAAAGcccaaaaacataaaaactttaaaaattaagtcaAGTACAACGAAAATAGAACAAATTGTTGATGTTAAAAAGGAGTTAAGTGATTCCGATGAGAATGAGAAATTAAGTAATGATGATGATAGCAACTACGAAGCAGATCAAAATAcaacagaatataaaaatcGAAAAGAAGACGATAGTTTTATTGCTgaacattttaaacaaatgtcATGCGATCTCTGCGAAGCtccatttgaaaacttttccgccttgaaaaaacaccttttattaaaacattcaatTCGAAAGGGATATGTAATATGTTGCAACAAAAAGTTATTCCAGTATAATCATTTGGTTGACCACCTGCAATGTCATCTCAATCCAGATTATTTTAAGTGTAGTCAATGCGGAAAAATTTTATCCGATCGAAAAAACTTACAAGCACACATGCTGCGCGTTCATCGTCCAAATGATGTTCCACCAAAACATTCTTGTGACGTTTGCGGAAAGTCGTTCACAATGGCTTACATTTTGCGCACTCACAAATTGAAACATTTGCCTAAAGAGGAAAAAAAGTTTCCATGCACAGAATGCGGCAAATTTTACGCAAGTTCCTACCTATTGAAAATACACACCGAagtaatacatttaaaaaaacttgcaCAAGTTTGTTACATTTGCGGGAAAACGTTACGCACCAGCACCGAATATAAAGCGCATATGAACAAGCATTCAGGACAAAATAATCCATCTTTAAATTGCGACGTATGTGGTTTGCGTCTAATAAGTGAACGAAGTCTCAAGCTTCATAAAGAATCACAACATCCAGAAGGGGGGAAGAAGGATCATCCCTGTCCAATATGTAACAAGATATCTCCAACAGCACGTGCACTAAAGAAACACATAAATACCATGCATGAAAAAGGTGTCGATCATAAATGCACGATATGTGAAAAGGCCTTTAGGAGACCGGAAGGTCTAAAgGAGCATATGGCTTCGCATACTGGAACCCCTTTATATTCGTGCCCTTGGTGTCCAAAAACGTTTAACTCGAATGGAAATATGCATGCACACCGAAAAAATAAACATCCTATAGAGACTTTAGAATTGAAACTACAAAAGTATAATTAA
- Protein Sequence
- MDCCLLCLKLNKDLMGYIVAHSEQWQELGITKLLEKHFWPLSNMQPSSWLCSSCWQELNNFHKFYLSIEEAHMALGRIKIEDESKEAIRQITDFAYLEPEILIDQAAVENKEFFVKLEGEEDDLNDYPVISADPLTKPLIIPKPKNIKTLKIKSSTTKIEQIVDVKKELSDSDENEKLSNDDDSNYEADQNTTEYKNRKEDDSFIAEHFKQMSCDLCEAPFENFSALKKHLLLKHSIRKGYVICCNKKLFQYNHLVDHLQCHLNPDYFKCSQCGKILSDRKNLQAHMLRVHRPNDVPPKHSCDVCGKSFTMAYILRTHKLKHLPKEEKKFPCTECGKFYASSYLLKIHTEVIHLKKLAQVCYICGKTLRTSTEYKAHMNKHSGQNNPSLNCDVCGLRLISERSLKLHKESQHPEGGKKDHPCPICNKISPTARALKKHINTMHEKGVDHKCTICEKAFRRPEGLKEHMASHTGTPLYSCPWCPKTFNSNGNMHAHRKNKHPIETLELKLQKYN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00899909;
- 90% Identity
- -
- 80% Identity
- -