Basic Information

Gene Symbol
-
Assembly
GCA_963675445.1
Location
OY776280.1:75326086-75328332[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.00024 0.029 16.0 3.7 2 23 198 220 197 220 0.96
2 13 0.0036 0.42 12.4 3.1 1 23 226 248 226 248 0.94
3 13 0.00026 0.031 16.0 2.2 1 21 254 274 254 276 0.95
4 13 0.00018 0.022 16.4 3.5 1 23 282 304 282 304 0.96
5 13 0.18 21 7.0 1.8 1 23 310 332 310 332 0.95
6 13 0.00019 0.023 16.4 0.8 2 23 393 415 393 415 0.96
7 13 9.2e-05 0.011 17.4 0.9 1 23 421 443 421 443 0.99
8 13 3.9e-05 0.0047 18.5 0.6 1 23 449 471 449 471 0.98
9 13 1.1e-05 0.0013 20.3 1.8 3 23 479 499 477 499 0.95
10 13 0.25 30 6.6 7.3 1 23 505 527 505 527 0.96
11 13 1.4e-05 0.0017 19.9 0.2 1 23 532 554 532 554 0.99
12 13 0.0013 0.15 13.8 4.0 1 23 560 582 560 582 0.97
13 13 7.6e-05 0.0091 17.6 4.1 1 23 588 611 588 611 0.98

Sequence Information

Coding Sequence
ATGGACTCCAAACTATGTCTAACATGTCTCTGTGAAGCTTCCAAGGCCCACAATGTAAATGAGATTATAATGGAAAATCTTAAAATACTAGAAATACTTCACCTGTTTGTACCGCTGTTTTCGAAACAAGAATTTATATTACCAGACACGATTTGTGCTAAATGTTTGGAGAAATTAGttatatcatttaaatttcGAAAACAATGCTTGGactcattaaaaaatgtatataaggtATGGCCAGCAAGCTCCTTGTATAAAGAAACTCCATATGAAGAGTCCTCACCAAAGCTGGAGGCTGAAAACGCTGAATTGGTATTAATGACTGATCATAATGATGACAGTACAGTGGGATCTTCTCCTGAAGCTGAAGAAGATTTGAAAATGGCATTTGAGGAAATTGCAGTTGATCCTTTAACTACAAATAAAACTCTACACGAACTTGTTCCTGATGACAACGAAATCGAAAAGGATAAGCCAATTCCTGAAGAATTATTAAATGATGAATTGGAATGTAACAAAAATAGTTACAAAAAGTTACACGAAAAGCCTGATGTAGAAGGTTTTAAGAAGTCATCAGTTGTTTCAAATCAGTGTAAACTTTGCAATAAAGTATTCAAACAGCACCAAGGACTGTCGTCGCACATGTCAAAGActcattttaaaaaacatttatatcgATGCCAAAAATGCGATAAAGGATTTAGCGTTGAAGAACTCTTTATAAGACACTGTAATCGCCACTTGGGTATCAAGCCTTTTCCTTGCACCCAATGCAGTAAAGCTTTTGACAGTAAAGGTACCTTAAATCAGCACATGCTTTGTCATTCTAAAGAGTCTTCTTACTTATGTACTATTTGTGGTAAGACGTTTTATCGTATGGATGTTTTCAAACAGCATATGCACCGTCATGACGACAGAAAACTATTCGAATGTTTAAAATGTTCTATAAGCTTTAAAAGTTTCGCTGATCATATAAAACACTTGGATATGCATAAACATGAGCAGTCCTACGACGGTAAAGATAAAACTGAGGATAtggaaaaattgaatataaaacaagaaaaaaatgatGGCGACGGaaatgaGATCGAATTTAAAATAGACCAAAAAACTACCTCTAATAATACTAAAGATAACGAAAATAATAATCCAACGATATCGACTGATTCAGCTCAATGTGATCTATGcaatcaagtatttaaaaattcacaagGATTGGCTAGGCACAGATCTAGTACGCATTTCAAAAATCACTTATACCAATGTGATCAATGTGATAGAGGATTTAGTGTGGAAGAATACTACATAAAACATCGCAATCGCCATTTGGGTATAAAAGCCTTTAAATGTAACCAATGTGACAAAGCTTTTGAAACTAATAGTATCCTCAATCAACATTTAATATCACATTCTAAACTTACACCACATTTATGTACAGCCTGTGGCAAAGGCTTTCGACGACTGGATGGCTTAAGGCAGCATATGCGACGTCACGCAGAAGAAAGGCCATTTAAATGTACACAATGTCCAAAAAGCTTCAAGTGTCACTCTGATAAGTTAAAACACGTTCTCAAACACGATGAAAAACGTTATGAGTGCAATATATGTGGCACACGTGTATCTACTCCCGAGTCACTTTCGCAACATAAAATGACACATACTGGCGAAAAGCCTTTTAAATGCAGTTTTTGCGATAAGAGcttCATCTCCTTGTCTAATATGAGATGTCACGAGAGAATACATACTGGCGAAAAACCTTACAAATGTCAATATTGTTGGAAATCATTTCGGCAAAGCAATGATCGCAAAAAGCACACAAACCGTTTGCATAAAAATGAGCAAAACGAAAAACACGTGGAGGAAAATCTATAA
Protein Sequence
MDSKLCLTCLCEASKAHNVNEIIMENLKILEILHLFVPLFSKQEFILPDTICAKCLEKLVISFKFRKQCLDSLKNVYKVWPASSLYKETPYEESSPKLEAENAELVLMTDHNDDSTVGSSPEAEEDLKMAFEEIAVDPLTTNKTLHELVPDDNEIEKDKPIPEELLNDELECNKNSYKKLHEKPDVEGFKKSSVVSNQCKLCNKVFKQHQGLSSHMSKTHFKKHLYRCQKCDKGFSVEELFIRHCNRHLGIKPFPCTQCSKAFDSKGTLNQHMLCHSKESSYLCTICGKTFYRMDVFKQHMHRHDDRKLFECLKCSISFKSFADHIKHLDMHKHEQSYDGKDKTEDMEKLNIKQEKNDGDGNEIEFKIDQKTTSNNTKDNENNNPTISTDSAQCDLCNQVFKNSQGLARHRSSTHFKNHLYQCDQCDRGFSVEEYYIKHRNRHLGIKAFKCNQCDKAFETNSILNQHLISHSKLTPHLCTACGKGFRRLDGLRQHMRRHAEERPFKCTQCPKSFKCHSDKLKHVLKHDEKRYECNICGTRVSTPESLSQHKMTHTGEKPFKCSFCDKSFISLSNMRCHERIHTGEKPYKCQYCWKSFRQSNDRKKHTNRLHKNEQNEKHVEENL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-