Basic Information

Gene Symbol
ZBTB41
Assembly
GCA_951813805.1
Location
OX638412.1:18965756-18974850[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 1.9 1.2e+02 4.1 3.9 1 23 89 111 89 111 0.95
2 19 0.0038 0.23 12.6 3.9 1 23 117 139 117 139 0.94
3 19 0.00014 0.0084 17.1 2.4 2 23 155 176 154 176 0.97
4 19 0.0013 0.077 14.1 1.9 1 23 192 214 192 214 0.98
5 19 0.99 59 5.0 1.1 1 23 268 290 268 290 0.97
6 19 0.00011 0.0066 17.5 3.2 1 23 296 318 296 318 0.99
7 19 0.017 1 10.6 1.1 1 23 324 346 324 346 0.96
8 19 0.16 9.5 7.5 0.1 1 20 351 370 351 372 0.94
9 19 0.77 46 5.4 0.5 1 23 376 398 376 398 0.97
10 19 3.5 2.1e+02 3.3 4.1 1 23 544 566 544 566 0.97
11 19 0.00012 0.0072 17.4 3.0 1 23 572 594 572 594 0.95
12 19 0.13 7.4 7.9 1.5 1 21 617 637 617 638 0.93
13 19 0.0032 0.19 12.9 0.8 2 23 645 666 644 666 0.96
14 19 0.064 3.8 8.8 0.9 1 23 672 694 672 694 0.97
15 19 0.15 8.8 7.6 1.4 1 23 699 721 699 721 0.96
16 19 1.5 90 4.5 0.9 1 23 824 846 824 846 0.96
17 19 8.6e-05 0.0051 17.8 5.1 1 23 852 874 852 874 0.97
18 19 0.014 0.81 10.9 2.7 1 23 880 902 880 902 0.96
19 19 0.057 3.3 9.0 1.5 1 22 908 929 908 929 0.96

Sequence Information

Coding Sequence
atggaagaaaaaaaagataaatcatTTGAAGAGATACAGCAAGAACAGGCAAAATCCACAAAAGAAAATAGCAACGAATTAGAAACAAATGATAACAAAACCACAAACACATCAATGCCCCAAACACAACAAATCAACGCAAGCGAATGCAGCAATTACAACGCTTACAACTTAAAAGATATTGTTGAAGTTACCAACGAAACAAACCTCAATCAAAATTTGACCGAGGTTGAAAATTTGCCACCTAAAAGCGTTGATCGCTTTTTCTTTTGCGATCTCTGCAACTTCTCAAGTCGTAGACACCGCTCGGTTAAGGTTCATAAATTGTTGCATTCTGGCGAACGTCCGTTCCTCTGCGATCTTTGCCCCGCCAGTTACACGAGAAAGCACCATTTGTTGAAGCACAGGAGTCTGCACATGACTGCGAAGGACGGCAAGGAATCCAAGACGATGACTATAATTACTTGTGATGTTTGTGGATTCACGTGTGCCCACAAGGCCAGTCTTCAGCGGCATCAATTGATGCACGCCGAGAAGAACCCGAACTGCGAAGAGCTGATGAATATGCAAAAGTTTCCATGCAATATTTGCAAATTGAAGTATACAAAAGAATTGCATCTTATTAAGCATTTGAAAATACACTTGGAAAAGGGAAATTTGGCCGGTTTTCTTTGCGACCCCTCCTCCAACAAAAGCCTACTGGATCAATTCTGCGACTTCAATCAATTTGATTACAACATACAACAAGAAGCCATCATATCCCAGCAATATCAGGACATCTGCAAAAAGATCAACGAAATATACCATTGTAACGCGTGCGAATTTACCACGAAAAACTTGGCATCTATCAAAGTGCACTACCTTATTCATACAGGCATAAAACCATACAAATGCGACTTATGTCCAGCAAGCTATAGACGCAAACAACACTTGCAATTGCATAGAAATCGGCACGATAAAGAAACGACTTATCTATGTCATCTCTGCGATTTTACAAGCATAGACAAATCGAGCATGGAAGTCCATAGAGAAATGCACGAGCCGAAATTGTACGAGTGTGATAGATGCAGGTTTAGTTTTGCAGAGTCCGAAGAATTGGATATTCATAGATTGAATTGCGTGCAATATATGTGCAGTATGTGTGCAACTATCTTTTTAGATAAACAGCTGTTTGAGAAACATGAATTGAGTCACGgtttagaaaatttgaaaactattGAATGTGAAAAGATATTGCAtaaatttgattcatttgaagaagttttgaatgcacaaATTGAGaTTAAAGAAGAAGAGGACTGTGATTCAGAAACAGACAACATTccactttcaaaaattaaaatcaaagtaGAAACAGCTTATTTCGAATCAAGCTATGACAGTAACGAAGCCGACAATCAACTTCTATATGACCACTCTGATTACGGGGACAATTGCAATGATAACGACACTGATTACGAAGCCTACAAGGAAGAGAAACATAACTTGAGCGATTACGAAGAAACAATTGCtgtaaagaaaaagaaaagcaAGAAAAAGAAACGTCTCTTGTCAAAAGTTGTTCAAAATGAAAAGAATATCGTTGTAAGAAAGTTCAAACGAAatcaagaaaagaaaatagacgGATTATACCACTGCAAATTTTGCAACTATTCTAataaacgtttaaattctgttaAAGTCCATCGCATGATACACACCGGCGAACGGCCTTTCTTATGCGACGTTTGTTCTGCCACATTCCGCCAAAAGGAACATCTAATAAAGCACAAAAAGACGCATGTTGGAATTAAATGCGAACGAAACGCGAGAGGAAATAGTAGCGAAATATACGACAGAGAAAAATCGTTTGTCTGTTCAAAATGCGGTTACATCTGTAGAATGAAGATTACGCTGGACAAGCACGAAAAGAAATGCTACAACGCCGTGTTAAAATGTTCAACTTGTGATGAAACTTTCTTAACTAGGAACGAACTTATTCGTCACAGATCTATTCACGTTGAACTGCGTAGCTACGATTGCGAACTTTGTGATTTTACAACTGGGAAtcttttgtatttgaaaaagcACACGTTGAAGCATTCCAAGATGTTATATTTGTGTTACGTGTGCAGTTTTACGACCGTGTATAAGTCTACTATGCAAGAACATAGACTCACACACAATGATAAGAAAGATCTGAATGATGTTAGAGATATGGATGGATGTAATTATAAATTAGAAGAAAAACAAGAGTATCTTGGCAGTAAGAATGCTCAACAAAATATCATGTATAATGATAGAATACAGGAATCCCCACAACACGTACAAGGACCATTACTAAACCACCCAGAAACAATAACAAACAGAATAAAGAAACCATCTCTTTACGACCCATTTGTGGACCCACAACTCGCACAAGGAACGATCAAAACCCAAGGACGACCACGCAAATACAAGCTGGGTGaattcaaaaaagaaaacgactTATACTTCTGTGATTTTTGCGATTATTCTAACACTCGTGTCAACTCTGTTAAAGTTCACCGGATGATACACACGGACGAACGCCCATTCTCTTGCGATCTGTGCTCCAAGTCTTTCAGGCAAAAGATGCACCTGAGGAAGCACAAGATCTCTCACACAAAGGAAAAGATGTTTGCCTGTGACGTGTGCGACTTTTCGTGCCGTTACAAGTCCAGTCTGGATCTGCACAAGTTGAAACATTCAGGAGTTAAACCGTACGTATGTGAAAAGTGCCTTTGTTCATATAGGACTCAACTAGAGATGGAACGACATGTCAGGAAATGTTCGTAA
Protein Sequence
MEEKKDKSFEEIQQEQAKSTKENSNELETNDNKTTNTSMPQTQQINASECSNYNAYNLKDIVEVTNETNLNQNLTEVENLPPKSVDRFFFCDLCNFSSRRHRSVKVHKLLHSGERPFLCDLCPASYTRKHHLLKHRSLHMTAKDGKESKTMTIITCDVCGFTCAHKASLQRHQLMHAEKNPNCEELMNMQKFPCNICKLKYTKELHLIKHLKIHLEKGNLAGFLCDPSSNKSLLDQFCDFNQFDYNIQQEAIISQQYQDICKKINEIYHCNACEFTTKNLASIKVHYLIHTGIKPYKCDLCPASYRRKQHLQLHRNRHDKETTYLCHLCDFTSIDKSSMEVHREMHEPKLYECDRCRFSFAESEELDIHRLNCVQYMCSMCATIFLDKQLFEKHELSHGLENLKTIECEKILHKFDSFEEVLNAQIEIKEEEDCDSETDNIPLSKIKIKVETAYFESSYDSNEADNQLLYDHSDYGDNCNDNDTDYEAYKEEKHNLSDYEETIAVKKKKSKKKKRLLSKVVQNEKNIVVRKFKRNQEKKIDGLYHCKFCNYSNKRLNSVKVHRMIHTGERPFLCDVCSATFRQKEHLIKHKKTHVGIKCERNARGNSSEIYDREKSFVCSKCGYICRMKITLDKHEKKCYNAVLKCSTCDETFLTRNELIRHRSIHVELRSYDCELCDFTTGNLLYLKKHTLKHSKMLYLCYVCSFTTVYKSTMQEHRLTHNDKKDLNDVRDMDGCNYKLEEKQEYLGSKNAQQNIMYNDRIQESPQHVQGPLLNHPETITNRIKKPSLYDPFVDPQLAQGTIKTQGRPRKYKLGEFKKENDLYFCDFCDYSNTRVNSVKVHRMIHTDERPFSCDLCSKSFRQKMHLRKHKISHTKEKMFACDVCDFSCRYKSSLDLHKLKHSGVKPYVCEKCLCSYRTQLEMERHVRKCS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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