Basic Information

Gene Symbol
-
Assembly
GCA_951813805.1
Location
OX638414.1:9839113-9841737[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 1.1 63 5.0 2.7 2 23 110 131 109 131 0.95
2 20 0.0036 0.21 12.7 6.6 1 23 137 159 137 159 0.98
3 20 0.0068 0.4 11.9 1.4 2 23 166 187 165 187 0.96
4 20 0.0081 0.48 11.6 4.0 1 23 193 215 193 215 0.96
5 20 0.0016 0.094 13.8 6.9 1 23 221 243 221 243 0.98
6 20 0.0016 0.097 13.8 1.3 1 23 249 271 249 271 0.98
7 20 0.14 8.2 7.7 3.9 1 23 277 299 277 299 0.98
8 20 0.002 0.12 13.5 4.5 1 23 333 355 333 355 0.99
9 20 0.00037 0.022 15.9 5.0 1 23 361 383 361 383 0.98
10 20 0.00037 0.022 15.8 3.4 1 23 389 411 389 411 0.98
11 20 0.14 8.2 7.7 3.9 1 23 417 439 417 439 0.98
12 20 0.0011 0.067 14.3 2.4 1 23 473 495 473 495 0.99
13 20 0.0011 0.067 14.3 2.4 1 23 501 523 501 523 0.99
14 20 5.5e-05 0.0033 18.4 3.0 1 23 529 551 529 551 0.99
15 20 0.0011 0.067 14.3 2.4 1 23 585 607 585 607 0.99
16 20 0.0011 0.067 14.3 2.4 1 23 613 635 613 635 0.99
17 20 5.5e-05 0.0033 18.4 3.0 1 23 641 663 641 663 0.99
18 20 0.0011 0.067 14.3 2.4 1 23 697 719 697 719 0.99
19 20 0.0011 0.067 14.3 2.4 1 23 725 747 725 747 0.99
20 20 5.5e-05 0.0033 18.4 3.0 1 23 753 775 753 775 0.99

Sequence Information

Coding Sequence
ATGGATATTAAGTCCGAACCAGTGACGATTCCTGAAGAAAATAGTCCTACATCGCCTAGTGACGCAATATTGCTGTTCGGGATTGTCAAACAGGAGACAGAAGAAGCTTTTGCTATCAAGTGTGAACCAGGGACTCTAGTGGCAGAAGAACATTCACAAGAATGTGGTGCATACTCCGAAATAGATTTTGACTATCCTGATATTAAAAAGGAGTGCTTTGTCCACCTTGAAAACATCGACCAAAATCgagATATCGTTTGcaaaacattcataaattgtacaaaacatccaaataaaaaaaaaactgtcataaGAAAGAAGTTACTCTGTTGCCCAACTTGCTCCTTCAGGTGTGGGCTTAAATCTAAACTGGTTGTCCACATTGGAACCcatactggagagaaaccattctcgtgctcgGAATGCACATACAAGTGCTCTCAAAGAAGCCATATGGTTTATCATATTAGgacccacactggagagaaaccgtTGTCGTGCTTGGAATGCCCCTACAAGTGCATTCAAAAAAGCAATATGGTTATTCATAGtagaacccacactggagagaaaccattcttgTGCTCAGAATGCCTTTATAAGTGCTCTAATAAAAGCAGTTTGGTTTATCATACaagaacccacactggagagaaaccattctcttGCTCGAAATGCCCTTATAAGTGCTCTAAAAACAGCAGTTTGGTTCATCATACaagaacccacactggagagaaaccattctcatgctcCGAATGTCCCTACAAGTCCACTCAAAAAAACACTATGATTATTCATACTAGAACCCACACTGGACAGAAACCATACTCGTGCTCGGAATGCCCTTATGAATGCTCTGCAAAAAGTAGTTTGGTTTGTCATACAAGAACCCACTCTGGAGAGAAACTATTCTCGTGCTCAGAATGCCGTTATGAGTGCTCTGAAAAAAGGCGTTTGGTTTGTCATACaagaacccacactggagagaaaccatacTCGTGCTCGGAATGCCTTTATAAGTGCTCTAATAAAAGCAGTTTGGTTTATCATACaagaacccacactggagagaaaccattctcttGCTCGAAATGCCCTTATAAGTGCTCTAATAAAAGCAGTTTGGTTTATCATACaagaacccacactggagagaaaccattctcatgctcCGAATGTCCCTACAAGTGCACTCAAAAAAGCACTATGATTATTCATACTAGAACCCACACTGGACAGAAACCGTACTCGTGCTCGGAATGCCCTTATGAATGCTCTGCAAAAAGTAGTTTGGTTTGTCATACAAGAACCCACTCTGGAGAGAAACTATTCTCGTGCTCAGATTGCCGTTATGAGTGCTCTGAAAAAAGGCGTTTGGTTTGTCATACaagaacccacactggagagaaaccatacTCGTGCTCGGAATGCCCTTATAAGTGCTCTGAAAAGGGCAGTTTGGTTTATCATACaagaacccacactggagagaaaccatacTCGTGCTCGGAATGCCCTTATAAGTGCTCTGAAAAGGGCAGTTTGGTTTATCATACaagaacccacactggagagaaaccatacTCGTGCTCGGAATGCCCTTATAAGTGCTCTGTAAAAAGCAGTTTGGTTCGTCATACAAGAACCCACTCTGGAGAGAAACTATTCTCGTGCTCAGATTGCCGTTATGAGTGCTCTGAAAAAAGGCGTTTGGTTTGTCATACaagaacccacactggagagaaaccatacTCGTGCTCGGAATGCCCTTATAAGTGCTCTGAAAAGGGCAGTTTGGTTTATCATACaagaacccacactggagagaaaccatacTCGTGCTCGGAATGCCCTTATAAGTGCTCTGAAAAGGGCAGTTTGGTTTATCATACaagaacccacactggagagaaaccatacTCGTGCTCGGAATGCCCTTATAAGTGCTCTGTAAAAAGCAGTTTGGTTCGTCATACAAGAACCCACTCTGGAGAGAAACTATTCTCGTGCTCAGATTGCCGTTATGAGTGCTCTGAAAAAAGGCGTTTGGTTTGTCATACaagaacccacactggagagaaaccatacTCGTGCTCGGAATGCCCTTATAAGTGCTCTGAAAAGGGCAGTTTGGTTTATCATACaagaacccacactggagagaaaccatacTCGTGCTCGGAATGCCCTTATAAGTGCTCTGAAAAGGGCAGTTTGGTTTATCATACaagaacccacactggagagaaaccatacTCGTGCTCGGAATGCCCTTATAAGTGCTCTGTAAAAAGCAGTTTGGTTCGTCATACAAGAACCCACATCAGAAAGAAACCATTATCGTCCTTGAAATGCACCTTTAGGGGAGCTCAAAAAAGCATTTTGGTTTCTCATACTAGAACATACGCTTTAGAGAAACCATAG
Protein Sequence
MDIKSEPVTIPEENSPTSPSDAILLFGIVKQETEEAFAIKCEPGTLVAEEHSQECGAYSEIDFDYPDIKKECFVHLENIDQNRDIVCKTFINCTKHPNKKKTVIRKKLLCCPTCSFRCGLKSKLVVHIGTHTGEKPFSCSECTYKCSQRSHMVYHIRTHTGEKPLSCLECPYKCIQKSNMVIHSRTHTGEKPFLCSECLYKCSNKSSLVYHTRTHTGEKPFSCSKCPYKCSKNSSLVHHTRTHTGEKPFSCSECPYKSTQKNTMIIHTRTHTGQKPYSCSECPYECSAKSSLVCHTRTHSGEKLFSCSECRYECSEKRRLVCHTRTHTGEKPYSCSECLYKCSNKSSLVYHTRTHTGEKPFSCSKCPYKCSNKSSLVYHTRTHTGEKPFSCSECPYKCTQKSTMIIHTRTHTGQKPYSCSECPYECSAKSSLVCHTRTHSGEKLFSCSDCRYECSEKRRLVCHTRTHTGEKPYSCSECPYKCSEKGSLVYHTRTHTGEKPYSCSECPYKCSEKGSLVYHTRTHTGEKPYSCSECPYKCSVKSSLVRHTRTHSGEKLFSCSDCRYECSEKRRLVCHTRTHTGEKPYSCSECPYKCSEKGSLVYHTRTHTGEKPYSCSECPYKCSEKGSLVYHTRTHTGEKPYSCSECPYKCSVKSSLVRHTRTHSGEKLFSCSDCRYECSEKRRLVCHTRTHTGEKPYSCSECPYKCSEKGSLVYHTRTHTGEKPYSCSECPYKCSEKGSLVYHTRTHTGEKPYSCSECPYKCSVKSSLVRHTRTHIRKKPLSSLKCTFRGAQKSILVSHTRTYALEKP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00898065;
90% Identity
-
80% Identity
-