Basic Information

Gene Symbol
ZFPM1
Assembly
GCA_947049285.1
Location
CAMRIN010000784.1:88024-93950[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 0.79 56 4.9 0.2 2 20 129 147 128 149 0.93
2 23 0.0089 0.63 11.0 2.9 2 23 181 202 180 202 0.96
3 23 0.00091 0.065 14.1 1.4 1 23 207 230 207 230 0.96
4 23 3.2e-06 0.00023 21.9 0.9 1 23 263 286 263 286 0.97
5 23 4e-05 0.0029 18.4 5.2 1 23 294 316 294 316 0.98
6 23 2e-05 0.0014 19.3 3.5 1 23 323 346 323 346 0.98
7 23 0.039 2.8 9.0 4.3 2 21 462 481 461 482 0.93
8 23 0.03 2.1 9.4 1.3 2 23 487 508 487 508 0.95
9 23 0.45 32 5.6 1.2 3 23 515 536 514 536 0.93
10 23 0.11 7.8 7.6 2.4 1 23 541 563 541 563 0.93
11 23 3 2.1e+02 3.1 0.5 6 20 570 584 568 586 0.92
12 23 0.0011 0.077 13.9 0.4 1 23 598 621 598 621 0.93
13 23 0.00036 0.026 15.4 2.8 1 23 627 649 627 649 0.98
14 23 0.061 4.3 8.4 1.7 5 23 659 677 657 677 0.97
15 23 0.26 18 6.4 0.7 1 23 683 706 683 706 0.86
16 23 0.0027 0.19 12.6 3.0 2 21 830 849 829 850 0.92
17 23 0.044 3.1 8.8 0.8 1 23 883 906 883 906 0.91
18 23 0.002 0.15 13.0 1.2 1 23 911 933 911 933 0.92
19 23 0.0001 0.0073 17.1 0.9 1 23 983 1006 983 1006 0.95
20 23 0.031 2.2 9.3 1.3 1 23 1012 1034 1012 1034 0.89
21 23 0.097 6.9 7.7 0.1 1 23 1040 1062 1040 1062 0.97
22 23 0.0043 0.31 12.0 0.9 1 23 1068 1091 1068 1091 0.94
23 23 0.00024 0.017 16.0 0.5 2 23 1098 1120 1098 1120 0.96

Sequence Information

Coding Sequence
ATGAATTATGGTAAGACAACAACAAACTATCTGACACATCTGGAAGGAACACCCACGCTGCCCGGTGGACTCTGCGAAACCTGCACTTCTTCCCTCTCCAGCTTCATACCCTTCATGCTATTATGTCGAGAATCCAATCGAAAGTGGACCCAAATCACTGACCATTTAGACACAGTATCAGTTAGCGGGCCAGCCAGTTCTGCCTATATCATTATAGGCGATGAACTCCAAGTATTGGTTAACAGAACCAACAAGAGAAATAAAACTCCTAAAGAAGTTCTAAAAAACATCAGAGTTAGAATGCATTCCGCTCGCTTCAAGCGAAAGAAAGTAACTTTAACACCACAAAAACTTAAGGCCCTAAATCATATGGGAACAAAATGGTCTTGTCCAGAATGTCAAGTGGAATTAAAGACTTTGTACAGGTTCAACAAACATTTGGAGTTTATTAGGAGACATTGCTGCGAGTATTGTTTCAAAATACTAAAAGCAGAAGATTTTGGACAACATCTTACTGAAATACATAACCTACAGAGTTGTCAATGCGAAGTCTGTAATTTATACTTTGAAGATGAAACATCTTTGGCAAGACACAGATGTGTTCACAACAGGGGAGATTTCGTGTGTCCGGAATGCAAACAGACTTTCGCTTCGATGTTCTGTTTGACAGCGCACACTAATTATGCGCATGGAAAAATCAAATGTGTTTGCGATGAACTATTCACAGGACATAGTTGCTATAATAATCACCGAAAGACCTGCACATATAATGTACAGACTAGTCAGTACGTGTGTGATTATTGCTCGAAGGCTTTCCCCCAGAAGGGTTCGCTGAGTCACCATATCAGAAATATTCACGAAGAGCCGAATGTCGCTGACCATCAGTGTCATAAATGCGGCAAGAGGTTCAGGAACAGTGCTACGTTGTTAGAACATTCCAACACTCACGATAAAGTTCTGGATAGATTTACTTGTAAATACTGCGACAAGAAGTACAGTACTAGTCGTGGATATCGGAAACATCTTAAAATGATTCACGCAGACATCGGTCCAGACTTGTATAAAAAGCTGCGATGCCATACGTGCCGAGTAGAGGAGGAGCCCAAGTTGCCGCCTGGCCTGTGCAGATCTTGCACAGAAGAAGTCGTTAGCGCTTTTAACTTCAAACAACTCTGCCGGACATCCGAGCGCCACTGGGCCGAAGCTACCGATCACCTGACAGCCATACGCGACCCAACTACCGAAGACAAGACGTATTTCGTCTTCTATTCGAATGAAGCCAATTTTTACAGCACTTCAGAAGTTGCTAATACAGCGAATAACGCTCTAAAGTATTTAAACAGGCCAAAACGCACGAGAACTTATAAGAGACCTCTCTCTTGTACATGTCCTTACTGCAACAAAAAGTTTAGATGCTTGGACGATCTGAACGAGCATTTGAAGTACACATCGAACCGATACTGTCCTGAATGCCATATCAGCGTCAGCAAGAAGAGTTTGGCGAAACACTTGCGTCTGAAACACAACATGAAAGTTGCGGCCTGTCCGTCATGCCACGAATTATTCTCGAAACAGATAGATGTTCAACGCCATTTTGACAAAAACCACGGGCCAGAATCTTATAATTGCTGCTACTGCGGCAGCGGCTTTCCCAATGAACGCGGGCTCAGAGCTCACAATCACTTGCACACGTTATTCACGTGCAGCTGCGGCGCGTCTTTCGAGAACAGCCGATGTCTCAAATACCACGCATCCATCTGCGCTTCGGAAAGACCAGAAACGGAGTCTGTTTTCGAATGCGACCACTGCGGAGTAGTTTATGATAAGAAGCCGTCTCTCCGCATCCACATAGTACAAAAGCATCTAAATGTGCTACCGTTCGTTTGCCAAACATGCGGCAAGCGTACATCAACTATCGCACATTTAAAATCTCACTCAAAGACTCACGAGACAACACGGAAGGTTCAAAGATGTCATTGCGGAGCGAATTTCCGTACCGCGTTAGGTTTCAAGCTTCATATGCGAATCCATTCTGGATTTAAGCCTTATAAATGTTCGCTCTGTGACGAGAGCTTCCTATCGGCCTCTAGACGGTTGGATCACGTTAAAAGACGCCACCAAACGTCGAGAGAGATGGCTCATAGTTGCAGCGAGTGTAGCGCTAAGTTCTTAATAGAGGAGCCGTCGTGTCCGCTCGGTGCGTGCGTCGAGTGCGCGAGCGCAGCGCTTGCCGCTCAAGAGTTCCGCCTTTTCGTGCGCAACTCTGAGAAAATATGGTACAAGACCTTACACAACCTCACAGATATCGAGTGTAACGACACGGACAACGCAAAATCCATATGTGCCTTCATAAAACCAACAGATTTGACTCTTATCACCGCCAAGGACTACTCCGGCGGAGAACCCACGGCCATAGTCAATCGCTCCAAGACGAAAGTGAAAAAAACTAAGCGCAAACCGAGAAGACACAAAAACGGTCCCACGACAACATGTCCAGATTGCCACAAAACGTTTACGAGCCCATTTTTCTTGCACGACCATTTCAAAAACAATGGCCCCAAAAGCGCATGCATAAGTTGTGGCGTCATTGTAGCCAGAGGCCAAGAGATGAAGGACCATATAGAGACCGTTCATAAGGAGAAGGCGTTCTTGTGTGCTCAGTGCCCCAGCGTGTTCACTAAGCGGGAAGAGTTCAATCAGCACACGAAAGATTCCCACAAGCCTGGAGTCTATAACTGTGCGGAGTGCGGCAGAACGTTCCCCAGGAAATCAACATTCGAGTTCCACTCACAGATGCACGTCGTGCGCACTTGCAGGAAGTGCGTCTGTCAGTTTACAAATAGGATCTGCTACAGGGAGCACCGAGCGCAATGCGAGCCGGAAGCGATGGTCAAAAAGGATACGTTGCCCAGAAACCGCAGGTCCAACGTGCGGGACCAAGCGGTGTTTATATGCGATTACTGCAACAAACATTACAGTTTACGTTCCGCCTTGCAGAATCACATACTCTGGATTCACATGAACCATAAGCCGCATCAGTGTCAGTGGTGTGGAAAGAGGTTCTTTACTTTAGGACGCATGACGGAGCACTCCGTTGTGCACACGCGAGAGCGGAACTTCGAATGTGACATCTGTGGCGCGAAATTAGTTTCCAAAATGGCCGCCGTGTACCATAGACGACGTCACACCGGGGAAAAACCTTACAAATGCGAGGATTGCGATCTTTCATTCATATCTTCGTCGCGTAGATTGGAACATGCTAAGCGAAAGCATAATAAAGGTAACAAGGCGCAGTGCGAGCTCTGTCCAAATACGTTCGCGAGGAAAACTGAACTTAAACGTCATGTGGAGAAGGTTCATAGAAATGTGAATACGGAAAAGTTACAATGGACCGAACCGATAACGCAAGCAGCGCAACCAGTCTAA
Protein Sequence
MNYGKTTTNYLTHLEGTPTLPGGLCETCTSSLSSFIPFMLLCRESNRKWTQITDHLDTVSVSGPASSAYIIIGDELQVLVNRTNKRNKTPKEVLKNIRVRMHSARFKRKKVTLTPQKLKALNHMGTKWSCPECQVELKTLYRFNKHLEFIRRHCCEYCFKILKAEDFGQHLTEIHNLQSCQCEVCNLYFEDETSLARHRCVHNRGDFVCPECKQTFASMFCLTAHTNYAHGKIKCVCDELFTGHSCYNNHRKTCTYNVQTSQYVCDYCSKAFPQKGSLSHHIRNIHEEPNVADHQCHKCGKRFRNSATLLEHSNTHDKVLDRFTCKYCDKKYSTSRGYRKHLKMIHADIGPDLYKKLRCHTCRVEEEPKLPPGLCRSCTEEVVSAFNFKQLCRTSERHWAEATDHLTAIRDPTTEDKTYFVFYSNEANFYSTSEVANTANNALKYLNRPKRTRTYKRPLSCTCPYCNKKFRCLDDLNEHLKYTSNRYCPECHISVSKKSLAKHLRLKHNMKVAACPSCHELFSKQIDVQRHFDKNHGPESYNCCYCGSGFPNERGLRAHNHLHTLFTCSCGASFENSRCLKYHASICASERPETESVFECDHCGVVYDKKPSLRIHIVQKHLNVLPFVCQTCGKRTSTIAHLKSHSKTHETTRKVQRCHCGANFRTALGFKLHMRIHSGFKPYKCSLCDESFLSASRRLDHVKRRHQTSREMAHSCSECSAKFLIEEPSCPLGACVECASAALAAQEFRLFVRNSEKIWYKTLHNLTDIECNDTDNAKSICAFIKPTDLTLITAKDYSGGEPTAIVNRSKTKVKKTKRKPRRHKNGPTTTCPDCHKTFTSPFFLHDHFKNNGPKSACISCGVIVARGQEMKDHIETVHKEKAFLCAQCPSVFTKREEFNQHTKDSHKPGVYNCAECGRTFPRKSTFEFHSQMHVVRTCRKCVCQFTNRICYREHRAQCEPEAMVKKDTLPRNRRSNVRDQAVFICDYCNKHYSLRSALQNHILWIHMNHKPHQCQWCGKRFFTLGRMTEHSVVHTRERNFECDICGAKLVSKMAAVYHRRRHTGEKPYKCEDCDLSFISSSRRLEHAKRKHNKGNKAQCELCPNTFARKTELKRHVEKVHRNVNTEKLQWTEPITQAAQPV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-