Basic Information

Insect: Leuctra nigra
Gene Symbol: znf423
Assembly: GCA_934046545.1
Location: CAKOHC010003026.1:31750-39572[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.49 35 6.3 5.9 1 23 3 25 3 25 0.98

2 24 2.6e-06 0.00019 22.9 4.1 1 23 31 53 31 53 0.99

3 24 4.1e-05 0.003 19.1 0.2 1 23 59 81 59 81 0.98

4 24 0.00017 0.012 17.2 0.4 1 23 109 131 109 131 0.98

5 24 0.011 0.78 11.5 0.1 1 23 221 244 221 244 0.91

6 24 1.7 1.2e+02 4.6 0.2 3 23 353 373 352 373 0.97

7 24 0.014 1 11.1 0.1 2 23 412 433 411 433 0.95

8 24 0.087 6.2 8.7 0.1 3 23 443 464 441 464 0.93

9 24 0.047 3.4 9.5 0.3 1 23 469 492 469 492 0.92

10 24 8.7 6.2e+02 2.4 1.0 1 19 539 557 539 561 0.77

11 24 0.26 19 7.1 7.6 1 23 565 587 565 588 0.96

12 24 0.79 57 5.6 2.3 3 23 622 644 621 645 0.89

13 24 0.0071 0.51 12.1 4.6 2 23 659 680 658 680 0.96

14 24 0.13 9.3 8.1 0.5 1 23 690 712 690 712 0.97

15 24 0.43 30 6.5 0.6 3 23 721 741 720 741 0.97

16 24 0.00012 0.0086 17.6 0.4 1 23 846 869 846 869 0.94

17 24 0.61 43 6.0 0.2 1 23 873 895 873 895 0.97

18 24 0.31 22 6.9 2.6 1 23 903 925 903 925 0.96

19 24 0.012 0.84 11.4 0.4 1 23 933 955 933 955 0.97

20 24 1.6 1.1e+02 4.7 2.0 1 23 962 984 962 984 0.96

21 24 0.0011 0.079 14.6 0.3 1 23 1031 1053 1031 1053 0.98

22 24 6.2e-05 0.0044 18.6 1.0 1 23 1063 1085 1063 1086 0.94

23 24 0.62 44 6.0 0.0 2 23 1104 1126 1103 1126 0.91

24 24 0.00025 0.018 16.6 0.7 2 23 1128 1149 1127 1150 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.49	35	6.3	5.9	1	23	3	25	3	25	0.98
2	24	2.6e-06	0.00019	22.9	4.1	1	23	31	53	31	53	0.99
3	24	4.1e-05	0.003	19.1	0.2	1	23	59	81	59	81	0.98
4	24	0.00017	0.012	17.2	0.4	1	23	109	131	109	131	0.98
5	24	0.011	0.78	11.5	0.1	1	23	221	244	221	244	0.91
6	24	1.7	1.2e+02	4.6	0.2	3	23	353	373	352	373	0.97
7	24	0.014	1	11.1	0.1	2	23	412	433	411	433	0.95
8	24	0.087	6.2	8.7	0.1	3	23	443	464	441	464	0.93
9	24	0.047	3.4	9.5	0.3	1	23	469	492	469	492	0.92
10	24	8.7	6.2e+02	2.4	1.0	1	19	539	557	539	561	0.77
11	24	0.26	19	7.1	7.6	1	23	565	587	565	588	0.96
12	24	0.79	57	5.6	2.3	3	23	622	644	621	645	0.89
13	24	0.0071	0.51	12.1	4.6	2	23	659	680	658	680	0.96
14	24	0.13	9.3	8.1	0.5	1	23	690	712	690	712	0.97
15	24	0.43	30	6.5	0.6	3	23	721	741	720	741	0.97
16	24	0.00012	0.0086	17.6	0.4	1	23	846	869	846	869	0.94
17	24	0.61	43	6.0	0.2	1	23	873	895	873	895	0.97
18	24	0.31	22	6.9	2.6	1	23	903	925	903	925	0.96
19	24	0.012	0.84	11.4	0.4	1	23	933	955	933	955	0.97
20	24	1.6	1.1e+02	4.7	2.0	1	23	962	984	962	984	0.96
21	24	0.0011	0.079	14.6	0.3	1	23	1031	1053	1031	1053	0.98
22	24	6.2e-05	0.0044	18.6	1.0	1	23	1063	1085	1063	1086	0.94
23	24	0.62	44	6.0	0.0	2	23	1104	1126	1103	1126	0.91
24	24	0.00025	0.018	16.6	0.7	2	23	1128	1149	1127	1150	0.95

Sequence Information

Coding Sequence: ATGCCGTTCCGCTGCGAGTTCTGCAGCCGATTGTTCAAACACAAGCGCAGCCGAGATCGACACATCAAGCTGCACACGGGCGACAAGAAGTACAGGTGCAGCCACTGCGAGGCCGCCTTCTCGCGCAGCGACCACTTGAAGATCCACATGAAGACGCACGACAATCAGAAGCCCTTCCAATGCACGGTGTGCAACCGCGGCTACAACACGGCGGCGGCGCTGACCTCGCACATGCAGAACCACAAGAAGGAGCAGCAGAACGGACTCAACAACAGCGGCAGCAGTCAGGGCGGCAGCAACACGCCCAGTCCCGGCGCAAACACGTTCAGATGTCTGCAGTGCGGAGACACGTTCCGCAAGCCCGAGGACCTGCAGGCCCACATGACGTCACACCAGCTGGACGCGTCCGGCTCGCCGCGGGGCCTGCTGGGGGGCCTGATGATGGGGGACCTGCCCCCGCTGATGCGCTCCCCCCTAGCGTTCCCACCCCCCAAGATGGCGTGCATCTACTGCACCAAGGACAGCTTCAACACCATGGAGGCGCTGCAGCTGCACGTCCAGGCCATGCATGGCTCCATCTTGAACGGGGATCTGCGAGACTTCCCGTCGCTGCGTCACCACTCGCACCCCCCGAGCCCGTCGCCGACCTCCTCGCCGCCCTACTCCTGCGAGCTATGCACCATGCGCTTCAGCTCTGCCCAAGCCATGCAGAAGCACGCTCTGGGAGTCCACGGTCTTCTGGCTCCTCCGCGCAGCTCCGCTTCGTCCCCCGGACTCTTCTGCATCCAGTGCTCGGTGTCGTTTCCGTCGGCAACGCTATTCGCCGATCATTACGTACTCATGCACGGACATCTCAATGGAGTGAGTCTGATGAACTCTTCGCCTCCGATCCCTGAACAGACCAAGCCGACGGATCTGAGCAAGAAGTCGAGATCATCGAAACACGTGGAGGAGCGAGTCGCCAAGCGGCAGAAGACTTCCGATGCAGTTCCGATGTCGAGCGCGGACTCCACCACAAGTCTCATGAATCAGTACGACCATCCCGGCACTCTTCTTTGTAATCAATGCAGCGCTGCTCTGCCCGACTTCGAGTCTTTCCGCAACCACTTGAAAGCCCATCTGGAGGAGGCCGGGGGTATTCGGGGCCTGCTGGGGGGCGGCATGGACCTCATTGGTCTTCTCGGGAGTCCTGAAGCTCGGCCCAAGAGCCCCGTGACGTCGTCCAACATCCTCTCCTGCCCTCACTGCGGGGCCAAGTTTGACGATCAGCCGGTCTTTGAGCAACACGTGGCCAGCCACTTCATGGCCACTGCGACAGAGTACGGCTGCCAGAGCTGCCTGAAGCTGTTTGCAAAGCCCGATGAATTGCAGAAGCATCTCATGGATATCCACGCTCACCATCTCTACAGATGCTCGCTGTGTAAAGAGATGTTCGACTCCAAGGTTGCGATTCAGGTGCACTTCGCCGTGAAGCACAGCAATGAATGCAAGATGTTTCGATGCACCGCGTGTGCCAACTCGAACGCGGTGTATCGGACGGAGGTGGAGTTTGCCACTCATGTCCGCAACACTCACGCGCTTCCCCTTCCGTCGGGTAAGAATCATCAGCCGCAGCATCGCTGTCTGTTCTGTCACCTGAGCTTCGCCACGGAGCTGGAGATGCAGTTCCATCTGGCGGCACACGCAAAGCAATATCACTGCCATCTCTGTCAAGAGGCATTCCACGTGGAGTTCCTCCTGGACAAACACATGCAGACGCATCACGAGCAGAAGTCGCCTAAGACGAACGGGACTCCGACGTCCAGCAGCAACACTCCGGTCTCCAACAACCACTCCGAGGGGAAGAAGGAGCCGACCGGCAGCTGCGACATCTGCGACCGCTGTGACTTTGCGTCTGAGTCTGAGCTGCAGTCGCATCGGAAGCTGGTGCACCACGTGAAGCCGAGCGCGGGGAAGAACGGCGCGGTGTCGCTTCACTGCGCGTACTGCAGTGAGAACTGCAAATCGCGAACCGAGCTGGAGAACCACATGAAGACGCACTCGCAAGGGTCCGGAGCTTCGGGGAAACACAAGTGCAACATCTGTGATGAACTCTGTCCGTCGGCTGCGGTTCTTGCGGAACACAAGCTCACGCACTGCAAGGTGGTGTCGGGCAGCGCCTGCACGCAATGCAAGGCTTCACTCAACAACGAGGATCAGTTCTACTCACATCTACAACAACACagcaataacaacaacaacaatggaTCCAATCAACAGGTGTTACTGCCGACACCATGCGTGGTTTGCCGACAAACACTGATCTCCGATATTGAGGTCAGAATGCACGCCAGATTCCATCTGAAGAACTCGTCCATGTCAGATGCTCTGTTTCAGTGTTGCTTGTGTTTGAAACAGTTCGAGTTTCACAACGTGATCATGGCTGGAGGCGGCAATGGAATCACACCGAACCTCCAGTCAGCGACTTATGTGTGTAAAGACTGCTATCATCTTCACCGCAAGCCGTCGCCAGCTCACCATCACGTGAGCGAGGACCACCGATGTCCAGAATGTCAGGTGAAGTTCGAAACATCGTCGGCCCTTGAGAAGCATCTCGTCTCCGTCCACCGCAAGACATATCAGTGCATCAAGTGTCAGGTGAGCTTCGAGACGGAGCGAGAGATTCAGCTCCACGTCGCCACACACATGCTGACCGACGGGTCGAGTCACGAATGTCACCTGTGTCGTCGTCATCTCGCCACTCCGCTGAAGCTGCAAGCGCATCTCATCGAACACACGTTTGCTGGCTGCGGGAGCTTCACTTGCTATCTGTGCAGCGCGGTCTTCACTGCGGCCCAGGGTCTGCAGCATCACATGCTGGAGCACGGCCTCTCGGCCCGACCCTACGACTGCACGAGATGCAGTCTACGCTTCTTCTTCCGCGCCGAACTGGACAATCACAGCTTCACGCATCTCGACGAGGATGCAGCCAGCGTCATGGCCGCCTCCTATCATCATCTCAATAACAACGGAGCTTACGACATGGAGGGTTTGAATTATTACAAGTCTGAAGCTGCGAAGAAGGCAAAGAGCAACGGAAAGTCCCCGATGTTTAAGTGTTTGGAATGCAACAAAGAACTGAGCAGTGCATTAGGTCTTCAGGCTCATCAGCGTTATCACAAACATGCTACGAAGGACAAGAAAACCCACGCCTGTGTCGAGTGCGGGAAGGAGTTTGCGCTGGCGCGGAATCTGAGCGTTCACATGCGTTCCCACCACGAAGAAGTATCGGAAGACGACGTGATGAACGGGAACCGGCTGGGTCTGGTGTACTGCCCCGTGTGTCGACAAGACTTCCCGGAGGTAGACCAGCTGGATGCGCACATCACCGCGCAGCACGTGCGATGCCCGCAATGTGGCGAGCCGTTCTCGCATCAGGAGTACGTGAACGAACACGTGCGGGCTCATCACGAGGTCAAGCAGGAGGTGGGGGAGGTCAAAGAGGAGAGAGTGGACGAGGAGGAGATCGACGTGTCGTCACCGGCTAATGATCGGGACGAATCGCTTCATGATGAAGCCAGCCAGGAATAG
Protein Sequence: MPFRCEFCSRLFKHKRSRDRHIKLHTGDKKYRCSHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKEQQNGLNNSGSSQGGSNTPSPGANTFRCLQCGDTFRKPEDLQAHMTSHQLDASGSPRGLLGGLMMGDLPPLMRSPLAFPPPKMACIYCTKDSFNTMEALQLHVQAMHGSILNGDLRDFPSLRHHSHPPSPSPTSSPPYSCELCTMRFSSAQAMQKHALGVHGLLAPPRSSASSPGLFCIQCSVSFPSATLFADHYVLMHGHLNGVSLMNSSPPIPEQTKPTDLSKKSRSSKHVEERVAKRQKTSDAVPMSSADSTTSLMNQYDHPGTLLCNQCSAALPDFESFRNHLKAHLEEAGGIRGLLGGGMDLIGLLGSPEARPKSPVTSSNILSCPHCGAKFDDQPVFEQHVASHFMATATEYGCQSCLKLFAKPDELQKHLMDIHAHHLYRCSLCKEMFDSKVAIQVHFAVKHSNECKMFRCTACANSNAVYRTEVEFATHVRNTHALPLPSGKNHQPQHRCLFCHLSFATELEMQFHLAAHAKQYHCHLCQEAFHVEFLLDKHMQTHHEQKSPKTNGTPTSSSNTPVSNNHSEGKKEPTGSCDICDRCDFASESELQSHRKLVHHVKPSAGKNGAVSLHCAYCSENCKSRTELENHMKTHSQGSGASGKHKCNICDELCPSAAVLAEHKLTHCKVVSGSACTQCKASLNNEDQFYSHLQQHSNNNNNNGSNQQVLLPTPCVVCRQTLISDIEVRMHARFHLKNSSMSDALFQCCLCLKQFEFHNVIMAGGGNGITPNLQSATYVCKDCYHLHRKPSPAHHHVSEDHRCPECQVKFETSSALEKHLVSVHRKTYQCIKCQVSFETEREIQLHVATHMLTDGSSHECHLCRRHLATPLKLQAHLIEHTFAGCGSFTCYLCSAVFTAAQGLQHHMLEHGLSARPYDCTRCSLRFFFRAELDNHSFTHLDEDAASVMAASYHHLNNNGAYDMEGLNYYKSEAAKKAKSNGKSPMFKCLECNKELSSALGLQAHQRYHKHATKDKKTHACVECGKEFALARNLSVHMRSHHEEVSEDDVMNGNRLGLVYCPVCRQDFPEVDQLDAHITAQHVRCPQCGEPFSHQEYVNEHVRAHHEVKQEVGEVKEERVDEEEIDVSSPANDRDESLHDEASQE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -