Basic Information

Insect: Leucozona laternaria
Gene Symbol: topi
Assembly: GCA_932273905.1
Location: CAKNZR010002225.1:988182-994156[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 2.9e-05 0.0052 18.5 2.8 1 23 212 234 212 234 0.97

2 10 3.1 5.6e+02 2.6 1.6 2 23 262 283 261 283 0.83

3 10 0.013 2.4 10.1 0.1 2 19 337 354 336 356 0.94

4 10 0.033 5.9 8.9 0.9 1 22 404 425 404 428 0.90

5 10 0.006 1.1 11.2 0.1 2 22 443 463 442 465 0.86

6 10 4.9e-07 8.7e-05 24.1 2.0 1 23 480 502 480 502 0.95

7 10 0.0024 0.43 12.4 1.0 1 23 508 533 508 533 0.95

8 10 0.43 77 5.3 1.6 1 23 539 561 539 561 0.88

9 10 1.8e-06 0.00032 22.3 1.0 3 23 569 589 567 589 0.98

10 10 0.034 6.2 8.8 1.4 3 23 597 618 595 618 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	2.9e-05	0.0052	18.5	2.8	1	23	212	234	212	234	0.97
2	10	3.1	5.6e+02	2.6	1.6	2	23	262	283	261	283	0.83
3	10	0.013	2.4	10.1	0.1	2	19	337	354	336	356	0.94
4	10	0.033	5.9	8.9	0.9	1	22	404	425	404	428	0.90
5	10	0.006	1.1	11.2	0.1	2	22	443	463	442	465	0.86
6	10	4.9e-07	8.7e-05	24.1	2.0	1	23	480	502	480	502	0.95
7	10	0.0024	0.43	12.4	1.0	1	23	508	533	508	533	0.95
8	10	0.43	77	5.3	1.6	1	23	539	561	539	561	0.88
9	10	1.8e-06	0.00032	22.3	1.0	3	23	569	589	567	589	0.98
10	10	0.034	6.2	8.8	1.4	3	23	597	618	595	618	0.95

Sequence Information

Coding Sequence: ATGAACTCTAGCAATTTTTGTGATGAAGACTTCCAAAATTCAGAAGCATGGCTTGCAGAGCAAATATTTTCACAGCTTAAAGATTTCAATACAACGGATTTAAAAAGTGATGTGGAATTAAAAAAAGAAAATGAAGACCTGAAAGAAACTGAGTCGGCAACAATCAATTCAGATGTAATTGATTTGGGGGAATTAAAATATGTCGGCCCACCTCCTGAAGCACCCCAACAACAGCAAATTATCTGCCCCAACCTCGAAATCCCCCAGGAACAATTGATAGGACCTGATTTAGTGAATCAAGAAAAAAAACAAAACCAAAACTTATTTACTTTTTTGGAGCCATCTTTTTTCTATCCACAAATTGTCGAATGTGCCAATTGCAATTGCGTTTTTGATGGCAATTCCTTCCACCAACACATCTGTGACTATGGCGAAGATAATAAGCTGATAGTTCCGGAGCCGACAGAACAATCTTTAGCTCCATTTGAACCTGGCCCAGTTGAGCCACCATGCATGCGTTTGTTGCGTGAAAATCAAATCCGCATCCGCCGTTTTCTTAAAGATGAATTAAAATACGATCTGAATGCCGCAGCCACTTCCGGGAGCACAGCCACAAAGAAACAAGACGGTCCACATGAATGTAATTTGTGTGAGAGAAAGTTTGTCCATGCTTCGGGGCTGTCACGTCACATGGAGAAGCATGCACTGGATCTGATTCCAACAACGACAACTGCACAAGCAACCAGCAGTTATTCTTCATGCAATGGTCTTAAAGTGGTTATTAAATGTACGACTTGTGGGCGGCTTTTTTTTGAACCTCAAACTGCCTACGAACATTTTTGCATCCATTTTCCTGAAATTACGGACAAAGAGGAATTTACAGAGGCTGCAGAATTCCCATACGAAAATTATTTAGATGATGCTATGGAACTGCTTAAAAAAGAATCGTCAGATTCGAACAACATGCCGACGATGCACCTGAAGATGGTAATTCTGAGCTGTGTTTTGCAATGTGAGTTCTGTGATATGATTTTCTCCCAGGTTTCATATTTGTTCGAACACTCGGCTTGTCATCGACCGGACAGACATTTTGAGTGCTCCTCATGTGAAATTCAAGTTTGTACTTCCAAAGAAATTTGCATGCATTGGCAGGCAGAGTGTGTTTTCTCGCGAGAAAAACTTAAACGCGGTTGCTCATCGCAAAGGTTCTACGTCTGCAATGTCTGTGAGAATAAATTTGGATCATTGGAAAGTTTGCATGAACATAGATACACGGCTTATCACTTCTTTCCAAGAGAAGACAACAATTCAAATTTACTATTGCTACCTTGCGAATACTGTGATCGGGTCTTTGAATCGGCCAGCGAAATTGTGGATCACTTTGAAGAAAAACACTATAAGAAGAACAAGCGGGATACACCGGCAAAATATCGACAATATTTGTGTGACATTTGTGGAAAAACATACACACAATCCAGTCATTTGTGGCAACATTTGAGATTTCATAAAGGTGTGAAGCCTTTTGCTTGTAAAGAACCTGGTTGTTCAAGAAAGTTCACCATACGTCCAGATCTAAACGACCACATTCGTAAATGCCACACGGGCGAGCGTCCTTATCATTGCCTCATCTGCGGTAGGCGTTTCTTAACTGGATCGGTATTCTATCAACACCGTCTTATCCACCGGGGTGAACGCCGCTACGGATGCGATGAGTGTGGAAAACGATTCTATCGCGCGGATGCCTTGAAAAATCATCATCGTATTCACACAGGCGAAAAACCCTTCGGATGTTTGTTCTGCACGAAAAATTTCCGCCAAAGAGGAGACCGAGACAAACACATCCGAGCTCGACACTCTAGTTTGGATGCCAATGCTCGTCTGATGATGCAAATGCGCAAGATGCAGCTGGAAGCAGCTGCCAGGGCTAGTTCCAGTTCAACAACACCAGCGGAGGAGGTTCTAATGTTGGGGAATATTCCCTTCCCCAGGAGCATGTTTCAGCCAATGTTGCCCGACATCGATGCAACATCGGGCCATGAATGA
Protein Sequence: MNSSNFCDEDFQNSEAWLAEQIFSQLKDFNTTDLKSDVELKKENEDLKETESATINSDVIDLGELKYVGPPPEAPQQQQIICPNLEIPQEQLIGPDLVNQEKKQNQNLFTFLEPSFFYPQIVECANCNCVFDGNSFHQHICDYGEDNKLIVPEPTEQSLAPFEPGPVEPPCMRLLRENQIRIRRFLKDELKYDLNAAATSGSTATKKQDGPHECNLCERKFVHASGLSRHMEKHALDLIPTTTTAQATSSYSSCNGLKVVIKCTTCGRLFFEPQTAYEHFCIHFPEITDKEEFTEAAEFPYENYLDDAMELLKKESSDSNNMPTMHLKMVILSCVLQCEFCDMIFSQVSYLFEHSACHRPDRHFECSSCEIQVCTSKEICMHWQAECVFSREKLKRGCSSQRFYVCNVCENKFGSLESLHEHRYTAYHFFPREDNNSNLLLLPCEYCDRVFESASEIVDHFEEKHYKKNKRDTPAKYRQYLCDICGKTYTQSSHLWQHLRFHKGVKPFACKEPGCSRKFTIRPDLNDHIRKCHTGERPYHCLICGRRFLTGSVFYQHRLIHRGERRYGCDECGKRFYRADALKNHHRIHTGEKPFGCLFCTKNFRQRGDRDKHIRARHSSLDANARLMMQMRKMQLEAAARASSSSTTPAEEVLMLGNIPFPRSMFQPMLPDIDATSGHE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00665153;
90% Identity: iTF_00665153;
80% Identity: -