Basic Information

Insect: Leucophora obtusa
Gene Symbol: Zfa
Assembly: GCA_949987735.1
Location: OX465296.1:20177030-20191294[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.33 35 6.8 6.3 2 23 45 65 44 65 0.96

2 20 2.7e-06 0.00028 22.9 1.5 1 23 73 95 73 95 0.97

3 20 0.002 0.21 13.9 2.3 1 23 101 123 101 123 0.97

4 20 1.4e-07 1.5e-05 26.9 4.2 1 23 131 153 131 153 0.99

5 20 0.0057 0.6 12.4 4.4 1 23 159 181 159 181 0.98

6 20 0.068 7.2 9.0 6.6 1 23 189 211 189 211 0.96

7 20 2e-05 0.0021 20.1 2.0 1 23 215 237 215 237 0.98

8 20 1.7e-07 1.8e-05 26.7 3.5 1 23 246 268 246 268 0.98

9 20 6.2e-05 0.0066 18.6 1.8 1 23 274 296 274 296 0.98

10 20 8.3e-05 0.0087 18.2 1.2 3 21 301 319 299 320 0.93

11 20 0.12 13 8.2 3.6 2 23 323 343 322 343 0.96

12 20 2.6e-06 0.00028 22.9 1.8 1 23 351 373 351 373 0.98

13 20 0.0073 0.77 12.1 2.0 1 23 379 401 379 401 0.97

14 20 1.9e-07 2e-05 26.5 1.9 1 23 409 431 409 431 0.98

15 20 0.00033 0.035 16.3 5.9 1 23 437 459 437 459 0.97

16 20 0.0013 0.14 14.4 3.5 1 23 467 489 467 489 0.97

17 20 0.0011 0.12 14.7 2.0 1 23 495 517 495 517 0.99

18 20 1.1e-07 1.2e-05 27.2 3.6 3 23 527 547 525 547 0.97

19 20 8.7e-07 9.2e-05 24.4 2.6 1 23 553 575 553 575 0.98

20 20 8.4e-08 8.9e-06 27.6 3.0 1 23 583 605 583 605 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.33	35	6.8	6.3	2	23	45	65	44	65	0.96
2	20	2.7e-06	0.00028	22.9	1.5	1	23	73	95	73	95	0.97
3	20	0.002	0.21	13.9	2.3	1	23	101	123	101	123	0.97
4	20	1.4e-07	1.5e-05	26.9	4.2	1	23	131	153	131	153	0.99
5	20	0.0057	0.6	12.4	4.4	1	23	159	181	159	181	0.98
6	20	0.068	7.2	9.0	6.6	1	23	189	211	189	211	0.96
7	20	2e-05	0.0021	20.1	2.0	1	23	215	237	215	237	0.98
8	20	1.7e-07	1.8e-05	26.7	3.5	1	23	246	268	246	268	0.98
9	20	6.2e-05	0.0066	18.6	1.8	1	23	274	296	274	296	0.98
10	20	8.3e-05	0.0087	18.2	1.2	3	21	301	319	299	320	0.93
11	20	0.12	13	8.2	3.6	2	23	323	343	322	343	0.96
12	20	2.6e-06	0.00028	22.9	1.8	1	23	351	373	351	373	0.98
13	20	0.0073	0.77	12.1	2.0	1	23	379	401	379	401	0.97
14	20	1.9e-07	2e-05	26.5	1.9	1	23	409	431	409	431	0.98
15	20	0.00033	0.035	16.3	5.9	1	23	437	459	437	459	0.97
16	20	0.0013	0.14	14.4	3.5	1	23	467	489	467	489	0.97
17	20	0.0011	0.12	14.7	2.0	1	23	495	517	495	517	0.99
18	20	1.1e-07	1.2e-05	27.2	3.6	3	23	527	547	525	547	0.97
19	20	8.7e-07	9.2e-05	24.4	2.6	1	23	553	575	553	575	0.98
20	20	8.4e-08	8.9e-06	27.6	3.0	1	23	583	605	583	605	0.99

Sequence Information

Coding Sequence: ATGATAACCATCTTCttttggccaaaattggatGATTTGGATATGGACGACATGTGGTGCCAACAGGACACCACTACGTGCCACACGGCTGATGCCACAATATACATTCTGCACGAGCAATTTGAGGAAACCGAATGTCATATATGCCACAAACGTTTAAAAAGAACAAGTCTAAAGAGTCACAGAAAAGTGCATATGGGAGAATCTGGAAAAATTTTCGAATGTCCACATTGCGATAAGAAGTTCAGATATCGTGGTGATTTAAACTCCCACGTGAGCGTTCATACTGGAGAAAAACCATTTGAATGTGATATATGTCACAAACTTTTCAGATTAAAAAATACTTTGAATGTTCACAAACAGTGGCATTTGGGAGaatctgcaaaaaaatttcaatgcAATTATTGTCAAAAGAAATTCTCAAATAGTTCTAATTTTAAAGCTCACCTTAAAACACATACTAGCGGTAGACCTTTTAAATGCGATTTATGCCACAAAAAATTACGCAATATCACAACTCTTAAACGTCATAAAATCAGTCATTTGGGAGAAGCTGGAAAAGTACATAATTGTGAATATTGTAGTATGAAATTCTTTTTCAAAAGTAAATTAGTAGCCCACACACGTCATCATTCATTACCATTTAAGTGCGATATGTGCCCTAAAAGTTATGAAACTAATGATAAACTTACTAATCACAAGCAAAGACATATAAAATCCAATAATGAACGGATTTTTAATTGTGAACATTGTGATAAGAAATTTAATCGTAGTTCTAATCTTAAAATCCATTTACGAGTTCATACTGGCGAAAAGCCCTATGAATGTGAGATATGTCACAAACGTTTTACAATAAGAGGAAATATGACAGCTCACAAAAAGATACATTTGGAAATAAATTGCGAATATTGTGATAAAAAGTTTCAACGAAATCAAGAGTTTCGGAAACACATGATGAGAGAAACCGAATGTGATATATGCCACAAACGTTTAAAAAGAACAAGTCTAAAGAGTCACAGAAAAGTGCATATGGGAGAATCTGCAAAAATTTTCGAATGTCCACATTGCGATAAGAAGTTTAGATATCGTGGTGAATTAAAGCCCCACATGAGGGTTCATACTGGAGAAAAACCATTTGAATGTGATATATGTCACAATCTTTTCAGTTTTAAAAACGCTTTAAATGCTCACAAAAAGTTGCATTTGGGAGAATctggaaaaaaatttatttgcGAATATTGTGAAAAGACattttttactagttctaatttaaaaattcaCCTTAGAACACATACTGGCGAAAGACCTTTCGAATGTGATATATGCCAGAAATGTTTTCGCAGTATAACACATCTAAAATCTCACAAAATCAGACATATGGGGGAAGCTGGAAGAGTTCATAGTTGTGAATATTgtgataaaaaattttttcttagAGCTGAATTAATGACTCATATACATATTCACACCGGCGAATTGTCTTATAAATGTGATGTATGCTCTAAACGTTTTCAAACTGCTGAACGACTTAGTGATCACAAAAAGAGACATATCGGACAAGTCGAACGGATATTGGATTGTGAACATTGTGATAAGAAATTTAAACGTAGTTCTAATCTTAAAGTCCATTTACGTACTCATACTGGCGAAAAACCCTATAAATGTGAGATATGTCACAAATGTTTTGCAGATAATGGAAATTTAATTGCTCACAAAAAGATACATACAAGCGATGCaggaaaaatatttaaatgtgAATATTGTGATAAAAGATTTAAACGAAATCTAGAGCTTCGGAAACACATGAGAGTACATACTAAAGAAACTACAAAATaa
Protein Sequence: MITIFFWPKLDDLDMDDMWCQQDTTTCHTADATIYILHEQFEETECHICHKRLKRTSLKSHRKVHMGESGKIFECPHCDKKFRYRGDLNSHVSVHTGEKPFECDICHKLFRLKNTLNVHKQWHLGESAKKFQCNYCQKKFSNSSNFKAHLKTHTSGRPFKCDLCHKKLRNITTLKRHKISHLGEAGKVHNCEYCSMKFFFKSKLVAHTRHHSLPFKCDMCPKSYETNDKLTNHKQRHIKSNNERIFNCEHCDKKFNRSSNLKIHLRVHTGEKPYECEICHKRFTIRGNMTAHKKIHLEINCEYCDKKFQRNQEFRKHMMRETECDICHKRLKRTSLKSHRKVHMGESAKIFECPHCDKKFRYRGELKPHMRVHTGEKPFECDICHNLFSFKNALNAHKKLHLGESGKKFICEYCEKTFFTSSNLKIHLRTHTGERPFECDICQKCFRSITHLKSHKIRHMGEAGRVHSCEYCDKKFFLRAELMTHIHIHTGELSYKCDVCSKRFQTAERLSDHKKRHIGQVERILDCEHCDKKFKRSSNLKVHLRTHTGEKPYKCEICHKCFADNGNLIAHKKIHTSDAGKIFKCEYCDKRFKRNLELRKHMRVHTKETTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -