Lvar002891.1
Basic Information
- Insect
- Leucophenga varia
- Gene Symbol
- -
- Assembly
- GCA_018903435.1
- Location
- JAEIFJ010001870.1:1555367-1559444[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0036 0.29 12.0 3.6 1 23 507 529 507 529 0.99 2 13 0.0059 0.47 11.4 0.6 3 23 575 595 574 595 0.96 3 13 0.00031 0.024 15.4 3.9 1 23 685 708 685 708 0.97 4 13 0.092 7.3 7.6 0.6 1 23 745 767 745 767 0.97 5 13 0.00057 0.045 14.6 2.7 1 23 773 796 773 796 0.94 6 13 0.43 34 5.5 2.9 3 23 805 826 803 826 0.93 7 13 0.0052 0.41 11.5 0.1 2 19 853 870 852 873 0.93 8 13 0.043 3.4 8.7 3.6 1 23 932 955 932 955 0.96 9 13 0.0041 0.33 11.9 0.2 2 23 994 1016 994 1016 0.95 10 13 0.016 1.3 10.0 2.2 2 23 1041 1063 1040 1063 0.94 11 13 0.028 2.2 9.2 0.3 5 23 1074 1092 1070 1092 0.91 12 13 8.6e-06 0.00068 20.3 3.1 1 23 1098 1120 1098 1120 0.98 13 13 2e-06 0.00016 22.2 1.7 2 23 1127 1148 1126 1148 0.97
Sequence Information
- Coding Sequence
- ATGTTGATACCAAGTGGCAAATCTCAAAATCACTTATCAGCAAATGATAAAATTTTGGCAAGTTTATGCGGTTTGCATACATCAAAAGTGGAGTTGGATGAAGATTCATTTAGTGGTTTTGAATTTAATACAACAACCAATTTAAATATTAAATGTGAGTCGGAAGCAATAAATGTAACAGATAGTACAACGCCACAAAGTGAAAGGAAACATAAAAACACAGAACAGGAAAAGTATATAATCAAATATATAGAAAAGACTCCACAAATGGTTAACATGAAGGGTCTCTGTAAAGCGGAACGAGATGCAATTTGGTTAGAACTAGTCGATAAGCTTAATTGCATGGGACCACCAAGAAAAGATTTAACTTCATGGAAAAAAAACAATCACTTAAAAAAGAAAATAAAAAGAGATGGTAAAGATGCTTTGTTTGGCAATGAAGATCATTTTGCACGACTAAATGGTCTATATGATCAATTTGATGAGATTAATAACAGCAACAATTTTAGTAAAAATCTAAACGAAACAACATCAACACAAAGTGCTGCTGCAACGGGGGAGGAGCAATGCATAAATAGGCCGCAAAAAAAATCTACTAGATGTAAATCAGAATGCAGAACATGCAGGATAAATAGTTCAATGCTACATAAATTAACTGAAGGCATACCAAGTTATCCGAATAAAACATTAAATGATCTGCTTAAGGAATTGGTGCAGCAAACAGATGAAACTGAGGCACATATGCTGCCGCAGCAATTGTGCTACGTTTGTACAAGCAAACTGCTCAATGCTTACGATTTTATGGTGCAAGTGCGTGAGACACATACGCAATTGCTTGCCGAATTAAAAATGCAGATGAACCACTATGAAGATCCACTGGAGAAATCTTTTTCAAATGATGATGAAGTTGAGGAAGATGTGGAAGAAGTAGAAAAGCATACGAAAATTAATAATGCTACAACTGAATCTCAACTCATCACTGAAACTAAGACACCAGCTGTGACCATCAAAAAATCAGAAAGACTTCGTATTAAAAGTGCATTTTCTTTGAACAAATCCGTATCCCAAAAAACATTAAATGTAACTACAAATAAAGCAACTGCCGCCACAAGTATGTCTACTAGAAAAGCAGAAGAATTTAAACATAAAAATACAAGTCAATTGAATAGAAAAATCAATCAACAACTCAAAGATCTCTTGGAATCAGATGATGACGCTCCGATATGCAGCATTAAAAAAATGAAAACGGAAAGCCCTGATTTACAAGATGAAGCACTAGAAATACCGGAAAGTATAGAAATAAATGCAATTACAAAATTGGAAATATTTGACGACGAAATTGAACAAAATGATGAGGATGGAAATTTAAATTATAAAGACGACACAGTGGCGGAAGATATGGAAGTGGATGATAATTCAATAAATTCTGATAATGATGTACAATCCTGCAGCAATCAATCTTCAAATGAGCCAATTCAGAATATGGAACGACAACAACAAAAGAGCGACGAAAAATTCTTTAAATGTAAAAAATGCCCGGCACAATTTTTCTGGCCGCACAATTTACAGTATCATATGCGTAAGCATCAAAATACCGAAAAGTTGGAATTCGTGTCCGTACTGCAATCGAAAGTTCTATCTAAACCAGCAAAATGTCCAAAACCAAAAGCCACAGATGTCGATCCAAATCTATGTGCTCCTAATGGCCCCAAACAAATATTGTGCATGATCTGTCAACGTATGTTTAATAGTTTTACCGAATTACGTACACATTTATTGGCGCATCCAGATATAGATTTTGAACTTTGTTCGGAGCTGGTTGATACGCTTTATGGTTACAATTCGAATACTTCGAAAGAGGAATTCGAACAACGTTTACAAACAGATTTGAATTTGGATAAACTAGCACCGTATTACATAATAACAAATCAAGCGGGCTATGAGCTGACGCTGGACAGTTCAGAAACTGAATTTGAAGCTGAAACGCAAGACGATGATGATGAGGAGACAGCGGCAAGCGACGTTAAACGGCGTACAATGAAACTTAATAGTTATAGATGCGAATTATGTAAGACAGAATTTTCGCGCAAATATCTACTCTACGATCATCAGCGACATGATCATGAATGGTTAGATGCGCAGCATGTTTGTTCACGTTGCGATGCACGTTTTCTGAGCAAACAAATTCTGGATTTGCATCAGCGTAAAAATTGTAAAAATCCCAGCAAACGTTTCATGTGTACCCGTTGTCCAGTAAGATTTTTCTGGAGACGTAATTTAAAAGCACATGTTGTTACGCATCGTGCGACGGAACCTTTCAAATGCTCTAAATGCGAACGTACATTTGCTGCAAAGCATGCACTTACCAAACACTTGTACAATGATCATCCTGCAGACAAAGAACTAATCTGCTGTAGTTGGTGTCCTCGTAAATTTTATCGTCGCGAAGTATTTTTAGAACATTCAAAGCGTAGGCATGGTATTGATGAACTACGACTGCCACTTGCCGAAACATTGGCACAAGCGACAATGGAACCGAATGGTACTAAGGATATTACATGTAAAGTTTGTAATGAGAAATTTGAACGAATTAGTGAATTACGTGAACATTTTCTTCTCGAGATGACCACACACCAGGAGTACAGTTCATTCAGTAGCTATTCGATTACCAATCAAGCAGGCTATGAACTGCATATTGACGATTCGGATACGGATGATGACAACAATGAAATTGATGCTGAGATATACGTGAAACCTAAACGTAAAAAAAATGTCATCGTTAAGAATATGCCATACAATTGTGATCTATGTAAAATACAGTGTATGCGCAAGTACCAAATGATGCGACATCAGAGAGACTTGCATAAATTTGCCCCTTCGCTACCGTATAATTGCGACAAGTGTGTTTTTAAGACAGTTTGTAAAGAGATTTTCCAAAGACATCAGCTATATCAATGCGATAATGCAGAAAAGCAAAATGTTTGTCAAATATGTGGTTATAAGTTTATGTGGAATGAAAATTTAGAACGACATTTAAGTATACAACATCCTGAGCCGACATTGACATTGAAGGAAGCTGCGGCGCAAAAAGCATTAAGTTCGGAAAATGTTAATAAACTGAAATGTCCACATTGCGATAAAACGTATCTGCTAGCAACATGCTTAAACAATCATATACGCGATATACATATAAACCAAAAGAAGAAATATCTTTGCATCACATGTGGCTGGGCAACTGAAAATCGTTCTAAACTAACAATTCATACGCGTTATCATACTGGTGAGCGGCCTTACTCATGTCATTTATGCGATAAAACTTATATAACTCGCTTCCAACTTACGCGTCATATTGCAAGGCACGATGAGAACAGAGATTGGAGTTGCAACGTATGTAATAGAGTATTCCATACGCCAATAAATCTGAAAAGGCATTTAAGAACACACGTTACCGACGAGTGA
- Protein Sequence
- MLIPSGKSQNHLSANDKILASLCGLHTSKVELDEDSFSGFEFNTTTNLNIKCESEAINVTDSTTPQSERKHKNTEQEKYIIKYIEKTPQMVNMKGLCKAERDAIWLELVDKLNCMGPPRKDLTSWKKNNHLKKKIKRDGKDALFGNEDHFARLNGLYDQFDEINNSNNFSKNLNETTSTQSAAATGEEQCINRPQKKSTRCKSECRTCRINSSMLHKLTEGIPSYPNKTLNDLLKELVQQTDETEAHMLPQQLCYVCTSKLLNAYDFMVQVRETHTQLLAELKMQMNHYEDPLEKSFSNDDEVEEDVEEVEKHTKINNATTESQLITETKTPAVTIKKSERLRIKSAFSLNKSVSQKTLNVTTNKATAATSMSTRKAEEFKHKNTSQLNRKINQQLKDLLESDDDAPICSIKKMKTESPDLQDEALEIPESIEINAITKLEIFDDEIEQNDEDGNLNYKDDTVAEDMEVDDNSINSDNDVQSCSNQSSNEPIQNMERQQQKSDEKFFKCKKCPAQFFWPHNLQYHMRKHQNTEKLEFVSVLQSKVLSKPAKCPKPKATDVDPNLCAPNGPKQILCMICQRMFNSFTELRTHLLAHPDIDFELCSELVDTLYGYNSNTSKEEFEQRLQTDLNLDKLAPYYIITNQAGYELTLDSSETEFEAETQDDDDEETAASDVKRRTMKLNSYRCELCKTEFSRKYLLYDHQRHDHEWLDAQHVCSRCDARFLSKQILDLHQRKNCKNPSKRFMCTRCPVRFFWRRNLKAHVVTHRATEPFKCSKCERTFAAKHALTKHLYNDHPADKELICCSWCPRKFYRREVFLEHSKRRHGIDELRLPLAETLAQATMEPNGTKDITCKVCNEKFERISELREHFLLEMTTHQEYSSFSSYSITNQAGYELHIDDSDTDDDNNEIDAEIYVKPKRKKNVIVKNMPYNCDLCKIQCMRKYQMMRHQRDLHKFAPSLPYNCDKCVFKTVCKEIFQRHQLYQCDNAEKQNVCQICGYKFMWNENLERHLSIQHPEPTLTLKEAAAQKALSSENVNKLKCPHCDKTYLLATCLNNHIRDIHINQKKKYLCITCGWATENRSKLTIHTRYHTGERPYSCHLCDKTYITRFQLTRHIARHDENRDWSCNVCNRVFHTPINLKRHLRTHVTDE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -