Lvar006411.1
Basic Information
- Insect
- Leucophenga varia
- Gene Symbol
- -
- Assembly
- GCA_018903435.1
- Location
- JAEIFJ010001211.1:194923-196284[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.0024 0.19 12.6 0.0 2 21 16 35 15 36 0.93 2 10 0.00012 0.0098 16.6 4.0 1 23 89 112 89 112 0.98 3 10 8.1 6.4e+02 1.5 1.2 1 22 119 140 119 140 0.88 4 10 0.0031 0.24 12.3 0.7 2 23 150 172 149 172 0.95 5 10 3.8e-06 0.0003 21.4 2.0 2 23 223 245 222 245 0.94 6 10 2.1e-05 0.0016 19.1 0.1 1 23 264 286 264 286 0.96 7 10 1.8e-05 0.0014 19.3 1.1 1 23 292 314 292 314 0.99 8 10 3.3e-05 0.0026 18.4 4.4 1 23 320 342 320 342 0.97 9 10 2e-07 1.6e-05 25.4 2.3 1 23 348 370 348 370 0.99 10 10 0.014 1.1 10.2 0.0 2 22 377 397 376 400 0.89
Sequence Information
- Coding Sequence
- ATGTTGATCAAGGCAACGGAGCAACCTAATGGCATGAAGCGTATTACCTGCAAAATCTGTCAAATACAATTTGAGCGTATTGCGGATTTAAGAGCACATATAACAATGGAATTAAGACTAAATTTAAACGCACATCAAAGCTATGAATCTTTGGCCAATTATTCAATTACAAATGAGGCTGGCTTTGAACTTCACCTAGATGATTCGGAAACGGATAATGATGATACTGCCAATAATAGCAGTACAACAGTGCAATCTATAGCATACAAATGTGAAATTTGTCAAGTGCAATGTCGCCGGCGTTATGAACTGTTTCAACATCAACGTTCAATGCATTGGCGTAATCCAGCACCGCATGCATGTGACAAATGCGTTTTCCGCAGTGTTTCTAAGCGTATACTGGAGCATCATCAGCAAACTCAATGTCAGAATGCATTGAAGCAGCTTAGCTGCGAATATTGCAATTACAAATTTATGTGGTCTGAAAATTTGGAGCAACATCGGAAAATACAACATGGTGACTCACTTGAAACAAAGCGGAATGCAGCGAATACTGATGCCACTACTGCTATAGAGGAAGTACATGGTGATACCATAACAGAACAACTGACAGTATCGCAACAAGAGAACAAAATCGTAACAACAGCAGCAACTGCAAATATTTTAAACTGTCCACATTGCGATAAAACTTATATGCATCAATCATGGCTTAACAATCATATACGTGATGTACACAATCTTGGCAACGATATTAATAATAAAAAGAAGAAAAAGGAAACGGAACGTAGATTTCTTTGTCCTCATTGCGGCAAGGAGGCATCATCTGCAGCTGCATTGGTAACGCATATACGACGTCATACGGGCGAAAGACCATATAAGTGCGACATGTGTGAGATGCGTTTCCCACGTAACAGCGAAATGCTGGAGCATCGGAGAAAACATACTGGCGAGAAACCATATCATTGTACTGTTTGTGGCAAGGATTTTGCTTATTCGCATAAACTGAAACGACACACGTTAATTCACACCGGCATGAAACCATACAAGTGTACACTCTGCGAAAAGAGCTATCGACAAAAAAAGGATCTCAATATACACATGCAAACACATACCGGCGATACAACAATTGAATGTGGCTCATGTGGCGAACGTTTTATTGAGCGTGTTGCACTGGAGAATCATCGTATTATGCGTGGACACTTTGAGAAGATACATTAA
- Protein Sequence
- MLIKATEQPNGMKRITCKICQIQFERIADLRAHITMELRLNLNAHQSYESLANYSITNEAGFELHLDDSETDNDDTANNSSTTVQSIAYKCEICQVQCRRRYELFQHQRSMHWRNPAPHACDKCVFRSVSKRILEHHQQTQCQNALKQLSCEYCNYKFMWSENLEQHRKIQHGDSLETKRNAANTDATTAIEEVHGDTITEQLTVSQQENKIVTTAATANILNCPHCDKTYMHQSWLNNHIRDVHNLGNDINNKKKKKETERRFLCPHCGKEASSAAALVTHIRRHTGERPYKCDMCEMRFPRNSEMLEHRRKHTGEKPYHCTVCGKDFAYSHKLKRHTLIHTGMKPYKCTLCEKSYRQKKDLNIHMQTHTGDTTIECGSCGERFIERVALENHRIMRGHFEKIH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -