Lvar022079.1
Basic Information
- Insect
- Leucophenga varia
- Gene Symbol
- -
- Assembly
- GCA_018903435.1
- Location
- JAEIFJ010001519.1:544643-555331[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 2.7e-05 0.0021 18.7 2.1 1 23 28 50 28 50 0.97 2 18 1.9e-05 0.0015 19.2 0.3 1 23 56 78 56 78 0.97 3 18 0.00098 0.077 13.8 0.5 1 23 84 106 84 106 0.95 4 18 1.9e-05 0.0015 19.2 3.1 1 23 112 134 112 134 0.97 5 18 4.3e-05 0.0034 18.1 4.7 1 23 140 162 140 162 0.99 6 18 7.8e-05 0.0062 17.3 5.7 1 23 168 190 168 190 0.97 7 18 3.8e-07 3.1e-05 24.5 4.3 1 23 196 218 196 218 0.98 8 18 1.4e-07 1.1e-05 25.9 2.4 1 23 224 246 224 246 0.97 9 18 8e-05 0.0064 17.2 6.7 1 23 252 274 252 274 0.97 10 18 1.1 90 4.2 5.6 1 23 280 304 280 304 0.88 11 18 1.2e-05 0.00099 19.8 4.5 1 23 310 332 310 332 0.98 12 18 9e-06 0.00072 20.2 8.1 1 23 338 360 338 360 0.98 13 18 7e-06 0.00056 20.6 7.8 1 23 366 388 366 388 0.97 14 18 8.2e-07 6.5e-05 23.5 7.7 1 23 394 416 394 416 0.98 15 18 4.6e-05 0.0036 18.0 6.9 1 23 422 445 422 445 0.97 16 18 0.00022 0.017 15.9 0.5 1 23 451 473 451 473 0.97 17 18 0.00097 0.077 13.8 4.4 1 23 483 505 483 505 0.98 18 18 1.1e-05 0.0009 19.9 1.6 1 23 511 534 511 534 0.96
Sequence Information
- Coding Sequence
- ATGGAAGGCGGCTTACAGGCTGTTGATGGACAACCGCCTGTAACATTAGCACCGGATGGAACACCAATTGCAACGGGCACGCATGTCTGCGATATTTGTGGCAAAATGTTTCAATTTCGCTATCAGCTTATTGTGCATCGTCGTTATCACAGCGAGCGTAAACCGTTTATGTGTCAGGTATGCGGACAGGGCTTTAATACGTCGCAGGATTTAACACGTCACGGTAAAATACATATTGGTGGCCCGATGTTTACGTGCATTGTTTGCTTCAATGTATTTGCGAATAATGCAAGTCTGGAACGGCATATGAAACGGCATTCAACCGATAAACCGTTTGCCTGTACAATCTGTCAGAAAACGTTTGCACGCAAAGAACATTTGGATAATCATTTTCGTTCGCATACGGGCGAGACACCGTTCCGTTGTCAATATTGCGCTAAGACATTCACACGCAAGGAGCACATGGTTAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCTTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGACAAACACCACATCAGTGCGATGTCTGCGGTAAGAAATACACACGAAAGGAGCATTTGGCCAATCATATGCGTTCGCATACCAACGACACGCCGTTCCGTTGTGAGATCTGTGGCAAGAGTTTCAGCCGAAAGGAACACTTCACCAATCACATACTCTGGCATACAGGTGAAACACCGCATCGTTGCGATTTCTGCTCGAAGACGTTTACACGCAAGGAACATTTGTTGAATCATGTGCGTCAACATACCGGAGAGTCACCACATCGCTGCTCATACTGCATGAAGACATTCAGCGGGCGACGTAAGGAGCACCTGGTCAATCATATACGGCAGCACACGGGTGAGACACCGTTCAAGTGCACCTATTGCACGAAAGCGTTTACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACCTATTGCACCAAGACGTTTACACGCAAGGAGCATCTGACGAATCATGTACGCCAACATACCGGTGATTCACCGCATCGTTGCACCTATTGCAAGAAGACTTTTACACGCAAGGAGCATTTGACCAATCATGTGCGTTTGCATACAGGTGATTCGCCACACAAGTGTGAATATTGTCAGAAGACGTTTACGCGCAAGGAACATCTAAATAATCATATGCGTCAGCATTCAAGCGATAATCCCCACACGTGCAATGTCTGTAGCAAGCCCTTCACACGCAAGGAACATCTAATCAATCACATGTCACGTTGTCATACTGGAGATCGTCCGTTTGCATGCGAAACGTGTGGCAAATCTTTTCCACTCAAGGGTAATTTGCTATTCCATCAACGCAGTCACACTAAGGGACAAGAAATGGAACGTCCATTCTCGTGTGAAAAATGTCCCAAGAATTTCATATGCAAGGGTCATTTGGTCTCTCATATGCGCTCGCATTCCGGCGAGAAACCACACGCATGTACGCTATGCAGCAAAGCCTTTGTTGAACGTGGTAATCTTAAGCGTCACATGAAGATGAATCATCCCGATGCAATGATGCCACCACCGCCTATACATCCACATCCGCAGATTCCGGCTGGTGTGCTTTCGCAATTAAAACAAGAAGTGAAGCCGATAATATCAACAATTCCACTTTCTGTACCGCATCAAGCGCCAACAATGCACACCATGAAACAAGAAGTGAAACCGATTATATTAAATATTGGACTGGTGGAACTGAATGACGATGTACTCGAAGTAATACTGCGCAATTTAAATATATTTCAACAATTTTTAATGGCCGAAATGCATACACGTTTCGGTAACATTGTACAAACTCTCTGGCGTACACGCATGCGTAATATTGTGCTCTATGAGGAAATGTTCCGCTTTGGCGAAGCAAAATATCCGCCTGATGAAATCTTTATAAATTTTATACGTGCCATTTTGCCACATATGCCACATCGTTTAATTTTGCATAATTTTGAAGTGGAAAAATTACGCCTATTGGATGAACAAGAATTTGAATCTATACATTCGTTCCAATGGATTGGACCATTTCAAGCCGAGGAGAACAAGGAAAACTTTTCAAGTGCACTATTCATGGATGAGGATATTTTGCTGTTACAGCGTATTTTTCCAAATTTAAAATCTTTAAAATTACGCGCTTGTCAAATAACCGGAAAATATTTACCCGGTTTGACGCATTTACGTGAACTCTGTTTGGATGATTGTCAGCATCTTGAGGCATATCATTTTTCTGAAGTCTTTCATCAGTTACGTTTGCGTAAATTCGATATAATGGGTGATTGTGATGAAGTGAATTGCTGTGATTTGGCTGATCTGCAAAGGTGTCCCACATTGGAACACATTAAAATTGCCGATTATCATTTATGTTATGAGGTCTATCATCTCAACGAGCTATTACGCATGCCAGCGTTGCGTAAACTTTCGATTTTATCCAAGAATTTCGTTTTCGATGTTATGGCACGTATGTCGCGTAATCTTATCAAAACCATTGAAGCATTTAAATTTACCGGTGTGCTGCCAAATTTTGGACGTTTTTTCAATGAAATTGGCAATATGGAATATTTGCAACGTCTTTCGATTTACTCATGTCGCATGGATCCCGATGTCGAGGGCATACGTGATCATATGCTGCTGGATGTTGCAAAAAAATTAACGGAATTAACTGAAATACATTTTTGTGCTTGTGATATGGAAAGCTACAAGGGTCTTTTACCTTTCGTTGCGTACTGTCGTCAGTTGCGTTTGATAAATGTTACCAATTCGAAGAATATTGGTAATAAATTTATCTGGCGCTGCATTGATCTTATAAAGAAACAGAAATGGCGCACCACACCAATTGAGATTTGGATCAGAAATAGTGATATCGATCGACGCATACAGGAGCATCCACGATTTTTGCCTTTGGAAAGACTGCTTAAGATTAATAATAAAAAAGTGACACACAATACAAATCTGCCGGGTGTATTGAAATTTACTTTTGCTCGATGA
- Protein Sequence
- MEGGLQAVDGQPPVTLAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFNTSQDLTRHGKIHIGGPMFTCIVCFNVFANNASLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNDTPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFSGRRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCTYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHTCNVCSKPFTRKEHLINHMSRCHTGDRPFACETCGKSFPLKGNLLFHQRSHTKGQEMERPFSCEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPIHPHPQIPAGVLSQLKQEVKPIISTIPLSVPHQAPTMHTMKQEVKPIILNIGLVELNDDVLEVILRNLNIFQQFLMAEMHTRFGNIVQTLWRTRMRNIVLYEEMFRFGEAKYPPDEIFINFIRAILPHMPHRLILHNFEVEKLRLLDEQEFESIHSFQWIGPFQAEENKENFSSALFMDEDILLLQRIFPNLKSLKLRACQITGKYLPGLTHLRELCLDDCQHLEAYHFSEVFHQLRLRKFDIMGDCDEVNCCDLADLQRCPTLEHIKIADYHLCYEVYHLNELLRMPALRKLSILSKNFVFDVMARMSRNLIKTIEAFKFTGVLPNFGRFFNEIGNMEYLQRLSIYSCRMDPDVEGIRDHMLLDVAKKLTELTEIHFCACDMESYKGLLPFVAYCRQLRLINVTNSKNIGNKFIWRCIDLIKKQKWRTTPIEIWIRNSDIDRRIQEHPRFLPLERLLKINNKKVTHNTNLPGVLKFTFAR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -