Basic Information

Gene Symbol
-
Assembly
GCA_035044805.1
Location
JAWNNP010002837.1:954309-957362[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00021 0.013 16.2 4.6 1 23 239 262 239 262 0.96
2 15 0.0072 0.44 11.4 1.3 2 23 303 324 302 324 0.96
3 15 1.9 1.2e+02 3.8 2.6 1 23 406 430 406 430 0.93
4 15 0.041 2.5 9.0 1.9 1 23 467 489 467 489 0.91
5 15 0.0013 0.079 13.8 0.3 2 23 497 519 496 519 0.94
6 15 0.027 1.7 9.6 1.7 2 23 527 548 526 548 0.95
7 15 0.011 0.69 10.8 0.1 2 21 575 594 574 595 0.93
8 15 0.0015 0.095 13.5 1.1 1 23 645 668 645 668 0.97
9 15 2 1.2e+02 3.7 3.4 2 23 706 728 705 728 0.89
10 15 0.0097 0.6 11.0 0.6 2 23 760 782 759 782 0.95
11 15 0.00029 0.018 15.8 0.5 1 23 797 819 797 819 0.96
12 15 0.00011 0.0069 17.1 3.0 1 23 825 847 825 847 0.99
13 15 0.0001 0.0062 17.2 5.6 1 23 853 875 853 875 0.98
14 15 2.9e-06 0.00018 22.1 3.8 1 23 881 903 881 903 0.98
15 15 0.072 4.5 8.2 0.0 2 20 910 928 909 930 0.93

Sequence Information

Coding Sequence
ATGGCGACGCTCTGTCGCACTTGTGATACCAACGCAGCCACAGAGCTGTACGAACTCCGGCTACCATACACCGAAAAGTATCCGGGAAAGGAATTGCTGGATTTGTTAAAGGAGCTAGTACAGATAAGTCATAATATGGCATATGAAACACAACTACCGCAGCACCTTTGTGGCAACTGcatgcaaaaattaaacaacgcCTACGACTTTATGATGCAAGCGCGCGGTGCCTATCAACGTCTGCTGGACGGTATCGAGCCGGACTTGAAGTTGGATATAGGCGATTATGCACAGGAAGCGTTGCCATTAGAGCAGTTTATGACTGTTAAATTGGAACCCGTCGGCGAAGAGACGCCGCATATGGGTTTAAACCAAAGAGATGTGAGCGATGAAGCGCGAAGCGATATATTTGATGAAGCTTCTAATCAGAAAAACTCCAGTGAGAAACAACAATTGGATCCTTTAACAATAATGCAACAAAGAAACAACAAAGCACAGCTTAGTAAAGAAGATTTAACTAGTAATAATGAGAGTGAGGACGACATTAGCAGCAGTGATGACGATGCACCACTATTAAGGCGTaaagtaaaaatacaaaaaagtaagCGTAAGCACACGAAATCATTTCCAGGCGAACGAGTTGATAAAACTGTTCCCTTAGAACGCAGTTCAAAAAATcacaagcaaaataatttaaagaaatctaGCGAGACTCACGCATGTACGCATTGCACACGTAAATTTCGACGTATAGAAACTTTAGAGAGGCATTTAAAAACCGCACATGCCGGAGCTGTAAACACTttaaaagaagcaacaaaatgCAACGAACGCACACTTTGCAAAACCAAACAAGCAAAGGAACTCGACTTGAATCTGTGTAGACCGCATGGTTGCAAGTTGATACAATGCATGATTTGTCTGCAGCACTTTACAAAAATTTCCGAACTACGTAACCATTTGAAGGCACATCCTGTTATTTCTACATTCTCAAACCACAAGGAAACCCTACAAGAAATTACCGAATCCTTCTATCCTAATATTAAAGGCGAAATTACGGAATCCGATTTGTTGACACGcataaaaaatgatttgaaggcagaaaagtttgtttatttctattCGATTACCAATCAGGCGGGTTACGAGTTAAGTTTGGATACTTCAGATACAGATAGCGATACGGATGAGCAAATGTTGGCCAATAAACACTTCTATGCGTGCGATTTATGCGAAAACACGAAATTTCGGCATAAATACCAAATCTACGAACATCAGCGAGACCAACATGCCTGGCAGGATGCACAACATGTGTGCCGGCGTTGTGACGCACGTTTTCTAAGcaagcagctgctgcagcatcaTTGCGAGTCACGATGTCGAAATTCTCAAAAACGTTTTCTGTGCAACAAATGTCCGCTACGCTTTCGCTGGAGACATAATCTTAAAGCGCATTACGGGGAACACAAAACTAAGgTACTGAATCTGTCATGTGAGCTGTGTAATCTTAGCTTTGACCGTAAGAAACCACTGACACTGCACATGATTAATGTACATACGGATGCAGAAAAGATTGTGCCTTGCCTCTGGTGTAATCGGAAATTCTATCGTCATGAATTTTTTGTTAAGCATCTTGCGCGTCACGGATTGAAGGAGTCAGATTTGCCAGAGGCTGAGATGTTAATCAAGGCAACCGAGAAGGTTAATGGCGCTAAACGTATTAGTTGCAAGATCTGTCAGATGCAATTCGATCACATTGCAGATTTAAGAGTACATATACAAATGGAGctgaaactaaatttaaatgctcATCAGAGCTATGAGTCAATGGAAAATTATTCCATAACAAACGAGACCGGCTTTGAGCTACACATAGATGACTCGGAAACGGATATTGATGAGCCTGTGGCCAATGCAAAGCAGTCCACGCATTACAAATGTGAAATATGTCAAGTAAAAGTTCGCCGGCGTTATGAAATGTTTCAGCATCAGCGTGCAATGCATTGGCGAGATACAATACCGCATACATGCGACAAATGCGTATTCAAATCCGTTTGCAAGcGCATATTGGAACGTCATCAGCAAACACAATGTCACAATGCATTAAAGAAACTCAGCTGCGAGcattgcaaatataaatttatgtggCCGGAAAATTTGGAACAACATTGCAAAATGCAGCACGGCGATGTGTTAAAGGCCAAAagtgttgctgctgcaacattaACTGTACAGGCAGAGCAAACGGATGACAAAACGGCACCAGCGGCGTTATTAAAGTGTCCACATTGCGAACGTACGTATATGCTACTAGCGCGTCTAAATAATCACATACGCGATGTGCATAGCGAAGGtactaaaaagaagaaagtggAATCGAAACCCAGATTTCTCTGTTCACATTGCGGCATGGAAGCATCATCAGCTTCTTCATTGGTTACGCACATTCGACGCCATACAGGTGAAAAGCCCTTCAAATGCGAATCATGTGAAATGAGTTTTCCCCGTCACAGCGAGCTGCTGCAGCATCGCCGGAAGCACACTGGCGAAAAACCATACCATTGTACCATTTGCGGTAAGGACTTTGCATTCTCACACAAACTAAAGCGACACACTTTGACGCACACCGAAGTGAAACCATACAAATGCACGCTCTGTGATAAGAGCTATCGCCGGAAAGAGGATCTCAATCTGCACATGCAACACCACACCGGCGACAGACCAATTGAATGTGGCACCTGTGGTGAACGTTTTATAGAGCGTATTGCATTGGAAAATCATCGTGTTATGTGTGCACAATTCGAAAAGATAGAATag
Protein Sequence
MATLCRTCDTNAATELYELRLPYTEKYPGKELLDLLKELVQISHNMAYETQLPQHLCGNCMQKLNNAYDFMMQARGAYQRLLDGIEPDLKLDIGDYAQEALPLEQFMTVKLEPVGEETPHMGLNQRDVSDEARSDIFDEASNQKNSSEKQQLDPLTIMQQRNNKAQLSKEDLTSNNESEDDISSSDDDAPLLRRKVKIQKSKRKHTKSFPGERVDKTVPLERSSKNHKQNNLKKSSETHACTHCTRKFRRIETLERHLKTAHAGAVNTLKEATKCNERTLCKTKQAKELDLNLCRPHGCKLIQCMICLQHFTKISELRNHLKAHPVISTFSNHKETLQEITESFYPNIKGEITESDLLTRIKNDLKAEKFVYFYSITNQAGYELSLDTSDTDSDTDEQMLANKHFYACDLCENTKFRHKYQIYEHQRDQHAWQDAQHVCRRCDARFLSKQLLQHHCESRCRNSQKRFLCNKCPLRFRWRHNLKAHYGEHKTKVLNLSCELCNLSFDRKKPLTLHMINVHTDAEKIVPCLWCNRKFYRHEFFVKHLARHGLKESDLPEAEMLIKATEKVNGAKRISCKICQMQFDHIADLRVHIQMELKLNLNAHQSYESMENYSITNETGFELHIDDSETDIDEPVANAKQSTHYKCEICQVKVRRRYEMFQHQRAMHWRDTIPHTCDKCVFKSVCKRILERHQQTQCHNALKKLSCEHCKYKFMWPENLEQHCKMQHGDVLKAKSVAAATLTVQAEQTDDKTAPAALLKCPHCERTYMLLARLNNHIRDVHSEGTKKKKVESKPRFLCSHCGMEASSASSLVTHIRRHTGEKPFKCESCEMSFPRHSELLQHRRKHTGEKPYHCTICGKDFAFSHKLKRHTLTHTEVKPYKCTLCDKSYRRKEDLNLHMQHHTGDRPIECGTCGERFIERIALENHRVMCAQFEKIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-