Basic Information

Insect: Lerema accius
Gene Symbol: ZFX
Assembly: None
Location: scaffold608:295004-302392[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 9.5 5.9e+02 1.2 0.9 3 23 256 276 255 276 0.93

2 18 1 63 4.3 0.5 6 23 288 306 288 306 0.97

3 18 1.7 1.1e+02 3.6 0.0 2 23 315 337 314 337 0.94

4 18 5.5e-05 0.0034 17.7 0.3 2 23 365 386 364 386 0.97

5 18 5.8e-05 0.0036 17.6 2.2 1 23 393 416 393 416 0.97

6 18 2.6 1.6e+02 3.0 0.1 1 23 422 444 422 444 0.88

7 18 2.9e-05 0.0018 18.6 1.5 1 23 450 472 450 472 0.98

8 18 0.00029 0.018 15.4 7.5 1 23 478 500 478 500 0.98

9 18 0.14 8.4 7.0 2.8 1 23 645 667 645 667 0.95

10 18 9.6e-05 0.0059 16.9 2.0 2 23 674 696 673 696 0.92

11 18 1.4e-05 0.00088 19.5 0.8 1 23 702 724 702 724 0.98

12 18 3.5e-06 0.00022 21.5 1.2 1 23 730 752 730 752 0.98

13 18 9.1e-05 0.0057 17.0 3.5 1 23 758 782 758 782 0.93

14 18 2.7e-05 0.0017 18.7 0.0 1 23 788 810 788 810 0.99

15 18 0.00012 0.0075 16.6 0.2 1 23 816 838 816 838 0.97

16 18 0.0042 0.26 11.8 0.4 6 23 848 865 845 865 0.99

17 18 0.00042 0.026 14.9 0.4 3 23 1103 1124 1102 1124 0.96

18 18 5.6e-05 0.0035 17.7 0.7 1 23 1130 1152 1130 1152 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	9.5	5.9e+02	1.2	0.9	3	23	256	276	255	276	0.93
2	18	1	63	4.3	0.5	6	23	288	306	288	306	0.97
3	18	1.7	1.1e+02	3.6	0.0	2	23	315	337	314	337	0.94
4	18	5.5e-05	0.0034	17.7	0.3	2	23	365	386	364	386	0.97
5	18	5.8e-05	0.0036	17.6	2.2	1	23	393	416	393	416	0.97
6	18	2.6	1.6e+02	3.0	0.1	1	23	422	444	422	444	0.88
7	18	2.9e-05	0.0018	18.6	1.5	1	23	450	472	450	472	0.98
8	18	0.00029	0.018	15.4	7.5	1	23	478	500	478	500	0.98
9	18	0.14	8.4	7.0	2.8	1	23	645	667	645	667	0.95
10	18	9.6e-05	0.0059	16.9	2.0	2	23	674	696	673	696	0.92
11	18	1.4e-05	0.00088	19.5	0.8	1	23	702	724	702	724	0.98
12	18	3.5e-06	0.00022	21.5	1.2	1	23	730	752	730	752	0.98
13	18	9.1e-05	0.0057	17.0	3.5	1	23	758	782	758	782	0.93
14	18	2.7e-05	0.0017	18.7	0.0	1	23	788	810	788	810	0.99
15	18	0.00012	0.0075	16.6	0.2	1	23	816	838	816	838	0.97
16	18	0.0042	0.26	11.8	0.4	6	23	848	865	845	865	0.99
17	18	0.00042	0.026	14.9	0.4	3	23	1103	1124	1102	1124	0.96
18	18	5.6e-05	0.0035	17.7	0.7	1	23	1130	1152	1130	1152	0.96

Sequence Information

Coding Sequence: ATGAATCATTTACCTTCAAGAAACACGGCGGAGGATCTTCCGGATCTCAGCACACCTCCGCCTCTTAAATTAAACATCAGATATCCCGATATAGTCACACCAGACCGTCTATCGATGAAGCACAATTACCACAACCTGTGTCGCCTGTGTGCCGATGAGACACCTGACATCATGCCTATATTCAAAGGCGAAGGGGTGAAGTACGACATTGCTGCCAAAATACGAAAATATATGAATCTGAGGGTGCTGGCGTCGGAGTTCCTGCCGGAGTTCATCTGCGCGGCGTGCGCCAGCACTCTACTGTCCTTCCACGAGCTGGTGCGCAGCGCGCGCATCACCGACTACATGATGCGGACCCACGTCGGCGCCTCGCCATCAATGCCCGTGCCGGCGCCGCTGCCCAGCTCCAGCTCCGGCAACGAAGTCATTAAGAATGGAGTCAAGTGTGAGCCGCCGGCCTCGTTACAATCTGTAATAAAAAATGTATTGACCAAATATTTCCATACCCTGAATATCGAAGCAGACAATGTGGACTTTGAGTACGTTTGCCAAAAATGTGACGCGATGTCTGTCGGAAACAAAATCGAGCATTTAACCGAACATCTAACGACGTGCCACGACACTGCAGTCGACTGTGAGCGATCGATTGACGAGTTTATCAGAAGCAACATCATGTTCGAGGAGACCTTAGCGATCGACGAATTTGGCGATGACCACGAGGGCAGCATGCGGTGCACGAGCGACGCGGACCTCCCGAAGTTTTGGTGTCCGTTTTGCGAAAGCATATTTTCCTCCCCGACGAGATTGCTATGCCATCTTGCCAAGCACGTGAACCTCGACCACGACGATGGAGTGATGTGCTGCGACACCGTCTACTGCGACAGAGAGTCTATCATGACGCATCTCCGACAACGACACGGCCAACGTTCGGCTACGGGAACGACGTGTCGGACGTGCGGATTCGTCGCCGAGGACGACGCGGGATTGCAAGAACACATCGATCGTTCCCACGTCGAAGCGCCGGCGATCTCGGCGGATCGAAACAAACCGAAAGCTTCGACCGGTCGGCTTCAACAAAAATACATTCGCGTCGAGTGCCCCGCCTGCAATAAGATATTCTCGAATAAATACAACATGTCGGTACACCTGAAGAGTCACAGCGCTGGACCGGAGACATACACGTGCGAAACCTGCAGCAAAAGTTACAGAAGTCGAGGGAGTTTGGCGCATCACCGGAAGGTGGTCCACGAGGGAGAGATGCGGCACGTGTGCGCGTCGTGCGGGGAGGGCTTCCCGTCGCGGCTGGCGCGGGACGTGCACGCGCGCCTGCACACCGGGCTCAGGCCCTACAGCTGCCGATATTGTGGAAAGTCGTACCGAGCTCGAAACACCCTAAACAGACACCTCGAGATGCACCTCGACGTCAGGAAATACTCTTGCCATCTGTGCCCGAAGAAGTTTAGGAAGAGTACACATTTAAGGTATCACTTAACCACGCACGACCAGAGGAGGGAATCGACGCTTCGAGTGGACCTCCAAAGGTGTGACGATGCCGGCGATCGCTTCCACGACCCGATCGACTGGACCGGCGAGCGGGAGCGCCGCGGCGGCCCGGACTCGTTTTCGGAGGATGACGCTCCGCTGTCGAATATCGCAGCTAAAAAATCGACCGAACTTTACGATAGACTTTACGCGGCGCTGGCGAACTTCAGGAGTCACTTCGAAAGCCAACACGAATCGCACGAATGTAATTATCCAGACTTCACGGATTCGAATGAATCTGGCGCAGAGGACGACGCCCTCGAAACGGAGCCGCCGGACCCGAGCGAGTACGACGACCTCACGCGGAGCAACATGAGGAGGGACCGAATGGACGAGGAGACCCGGCTCGAACTGAACGAGGTGCGCACTAAGCTCGACGGGAAGGTATCCTACGCTTGCAAGACGTGCGGGAAGAAGTTGAGCTCGGCGCACTCGTACCTATTCCACAAGAGAATCCACACCGGCGAGCGGCCGTGCGTGTGCCACGTGTGCGGCAAGCAGTTCCGGGCGCCGAGCGGCCTGCAGCGCCATCTCACGGAGACCCACGAGCGGCTGCGCCGATACTCGTGCACGCTGTGCCCCAAGATCTTCGTCAACCTGCAGAACCTCAAGCAACACTTCCGGATCCACACCGGCGAGCGGCCGTTCGAGTGCGGGCAGTGCGGCAAGCGGTTCACGCAGAGCGGCAGCCTGCACGTGCACGCGAGGAGCCACAGCGAGCGGCCGCCGCACGAGTGCGCGGAGTGCGGCTGCGGCCGCGCCTTCGCACGCAAGACTCATTTACAAGACCACCTGCGCTCACACTGCGACGCTCGCGACTACGTCTGCGACGTCTGCGGAAAGGCGTCCAAGTCCGCCGCCGCGCTCCGCATGCACGCGAGGACCCACGGCGCGCCCTGCAGGTTTCGATGCATGGAGTGCGGATCGGAGTTCAAGCGAAACGGCGAGCTGAGGGCTCACGTGACGATTCACACGGGCGAACGGGCTCACCGATGCCCTTGCGGCAGGGCCTTCCGGCTGCGCGGCCAGCTCACGGCTCACGCGAGGACCCACGCCGCGAAGCCGAACGTCGACGAGTACGTAGACGTCGGCACCGACGCCCCGAAGATGCCCGAGTATCGCCACTGCAGGACCTGCTCGCTGCACCGGCCCGCCAGGCGGTACAACTTCCACGTCGCCAATCGACTCAGCAGGGTGGTGTACCGCTGCGAGGAATGTAGCTCGTACCTCGACAAGGACGACGTCCTTTTCCACTTGGACACTAACATCTTCGAGGACCTTCCGGACCACGTTAAGGAAGACTATTATAAAACCGAGAAGGCCTACTTGGAGGAGCAGGCGAAAGTCGATCCGCAAGCTAAGATCGACCTCGATCACCTCAACGACTACTTCCGTAAAAAGGCGGAGGAGGATGCAGTAAAGCGCGAGCGTGGCGCCGGAGCTCCGCCGGGGCGGACCGAGGACGAGCGACTGGCGAGAGGAGCCGGAAGAATAGACGAGGCGGGCCCGGCCACCGAGCGGAGCGCCGACAGGTCGAGCGACGAAGGGCGGTCGGAGGCAGATTCCGACGAGGACCCGTTGACGCCCAAACGAGAGCCAGTCGAGTCGTCGGAGTCCTCGCCGGTGAAGCGCCCGAAGAAGCGAGTGTCGATCGCCAGGAGCGGCCAGCGGGGGAAGGAGCTCGCCGACCACGACGACGAGGACGGCGCCGACGACGAGGTCGACAGCTCCCCGGCGGCCCACTCGCCCAAGGCCTCCCGGGCGTGCCCCATCTGCGGCAAGCAGTACCGCGCCTCCTCGAGCTACTTCTATCACATGAAGTACTTCCACAAGCGCAGCCGCGAGCACGAGTGCTCCGTGTGCAACAAGAAGTTCGGCACGAAGGCGAACCTCGCGCAGCACGCGAGCATCCACACGGGCGCGTACGACCTCGAAATGTACGTGGAATACCGACAGTTGTATTACTCCATCGGTACCAAACCAACATTCGCCGTCGCATCAAATCTAACATCACATCGTTTGAAAAAACGCCAAACGTACTTAGCTGACGCCCCCTCAAATAGATTTGGACCATAA
Protein Sequence: MNHLPSRNTAEDLPDLSTPPPLKLNIRYPDIVTPDRLSMKHNYHNLCRLCADETPDIMPIFKGEGVKYDIAAKIRKYMNLRVLASEFLPEFICAACASTLLSFHELVRSARITDYMMRTHVGASPSMPVPAPLPSSSSGNEVIKNGVKCEPPASLQSVIKNVLTKYFHTLNIEADNVDFEYVCQKCDAMSVGNKIEHLTEHLTTCHDTAVDCERSIDEFIRSNIMFEETLAIDEFGDDHEGSMRCTSDADLPKFWCPFCESIFSSPTRLLCHLAKHVNLDHDDGVMCCDTVYCDRESIMTHLRQRHGQRSATGTTCRTCGFVAEDDAGLQEHIDRSHVEAPAISADRNKPKASTGRLQQKYIRVECPACNKIFSNKYNMSVHLKSHSAGPETYTCETCSKSYRSRGSLAHHRKVVHEGEMRHVCASCGEGFPSRLARDVHARLHTGLRPYSCRYCGKSYRARNTLNRHLEMHLDVRKYSCHLCPKKFRKSTHLRYHLTTHDQRRESTLRVDLQRCDDAGDRFHDPIDWTGERERRGGPDSFSEDDAPLSNIAAKKSTELYDRLYAALANFRSHFESQHESHECNYPDFTDSNESGAEDDALETEPPDPSEYDDLTRSNMRRDRMDEETRLELNEVRTKLDGKVSYACKTCGKKLSSAHSYLFHKRIHTGERPCVCHVCGKQFRAPSGLQRHLTETHERLRRYSCTLCPKIFVNLQNLKQHFRIHTGERPFECGQCGKRFTQSGSLHVHARSHSERPPHECAECGCGRAFARKTHLQDHLRSHCDARDYVCDVCGKASKSAAALRMHARTHGAPCRFRCMECGSEFKRNGELRAHVTIHTGERAHRCPCGRAFRLRGQLTAHARTHAAKPNVDEYVDVGTDAPKMPEYRHCRTCSLHRPARRYNFHVANRLSRVVYRCEECSSYLDKDDVLFHLDTNIFEDLPDHVKEDYYKTEKAYLEEQAKVDPQAKIDLDHLNDYFRKKAEEDAVKRERGAGAPPGRTEDERLARGAGRIDEAGPATERSADRSSDEGRSEADSDEDPLTPKREPVESSESSPVKRPKKRVSIARSGQRGKELADHDDEDGADDEVDSSPAAHSPKASRACPICGKQYRASSSYFYHMKYFHKRSREHECSVCNKKFGTKANLAQHASIHTGAYDLEMYVEYRQLYYSIGTKPTFAVASNLTSHRLKKRQTYLADAPSNRFGP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -