Basic Information

Gene Symbol
-
Assembly
GCA_963675555.1
Location
OY776681.1:83817130-83836501[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 0.048 8.9 9.1 6.2 1 23 294 317 294 317 0.93
2 23 0.0046 0.85 12.3 6.6 1 23 326 348 326 348 0.98
3 23 0.0061 1.1 11.9 2.0 1 23 357 380 357 380 0.95
4 23 0.0069 1.3 11.7 1.2 2 23 396 417 395 417 0.97
5 23 0.00011 0.021 17.3 4.6 1 23 426 448 426 448 0.98
6 23 0.2 37 7.2 0.3 1 23 457 480 457 480 0.96
7 23 0.0041 0.76 12.5 0.3 2 23 496 517 495 517 0.96
8 23 0.0021 0.39 13.4 4.0 1 23 526 548 526 548 0.98
9 23 0.00061 0.11 15.1 2.1 1 23 557 579 557 579 0.98
10 23 6.9 1.3e+03 2.3 8.9 1 23 588 610 588 610 0.98
11 23 0.22 41 7.0 5.9 1 23 906 928 906 928 0.98
12 23 0.012 2.2 11.0 6.8 1 23 937 959 937 959 0.98
13 23 0.002 0.37 13.5 2.2 1 23 968 991 968 991 0.95
14 23 0.017 3.1 10.6 0.7 2 23 1007 1028 1006 1028 0.97
15 23 0.002 0.38 13.4 6.7 1 23 1037 1059 1037 1059 0.98
16 23 0.13 24 7.7 0.4 1 23 1068 1091 1068 1091 0.92
17 23 0.31 58 6.5 0.3 3 23 1108 1128 1106 1128 0.91
18 23 0.0038 0.7 12.6 6.6 1 23 1137 1159 1137 1159 0.98
19 23 0.0048 0.89 12.2 2.3 1 23 1168 1191 1168 1191 0.96
20 23 0.011 2.1 11.1 1.2 2 23 1207 1228 1206 1228 0.97
21 23 0.0036 0.66 12.6 4.6 1 23 1237 1259 1237 1259 0.98
22 23 0.00095 0.18 14.5 1.3 1 23 1268 1290 1268 1290 0.98
23 23 1.4 2.5e+02 4.5 8.7 1 23 1299 1321 1299 1321 0.98

Sequence Information

Coding Sequence
ATGACCGACGAAAAATGCACCATATGTAGACTTTGTTTACGCGTAGTCTCTGATAATTCAATGAAGCCTTTAGAAGAAATAGCGAATATTGTTCAAAGTATTCTTCCAAGATTGAACTTAAATATCATAAGTAATCCTATGATATGTAGTACATGTAACGAGTTGGTACAAAAATCATATGAGTACAAATTGTTTTGTCTGGGAACTAATAAATTGTACATGGAAGAAAATATTCACCCTGAATTGTTAAAAGAAATGAAGAAGGAGACAACAAATGATAGTAACAACTGCTGCAGATCTTGTTCACAACCTGTTAATAAAAATGATCTTAGAAAACTAGGTAATGTGGATGCTGGTATGATGGAAGTATTTATTCCAAAATTGgaTCCACCTCTTATGCAGAATGATATATTATGTGAAATGTGTTTAGATAACATACAAGTCCATTATAATTTGGTCGAAATGTGTTCAAATGTAGAAGAAAGAATTAATATTTACTGTAAAGCCTATGCTAATGATACCATTGGTGAAGTTGACTTGCTAGATATCCTTGAATTTTCATTAAATACGGACAATTATATTGACAAGCTTgaaattaaagaagaaaaattgGAGGATACTGATTTGCCAGCGGGAGATATTTTTAGGGAGATGAATGAGAACTGGCTGGCAAAAGAAGAAATCCCCTTTAAAGACGAATCTGAAGTGTATGACACTCATGTAGATTTagaAGCACTCAAAGTTGAAAGCCAACAGGCACCCGAACAAGCAGTCAATGAAATTGCATTGAAACGTACAGAACGTACCTACCTAACCAagaataaacaattttttgtaaGAAATCTTGATTTTCATAACGGCACAAGCAATGTGCACAGGTTCAAATGTCACATTTGTACTTACCAGTGCAGTTTTAAATATCTCCTGACAAGACATAATATGCTGGTACACAAGAACCCAGCAGAATTAGACATGTTCAAATGTCACATTTGTACTTACCAGTCCAAGTTAAAATATCACCTGACAAAACATATGTTGGTGCACAGGGATCCATCAGAATTAGACATGTTCAAATGTAGTCAATGTAGATATCAAGCAAAACGAAAAAGGGACTTAAAAAGACATATTGTGTCGCTTCACGGAGATTCATTCATCCTTACTAGggaaaatgaagaaaatacaTTGGAATGTACAAAATGTACTTACTTAACAACAGATAAATACTTATTTGAAAAACATCTTAGGGTTCATATAGACCTAAACGAGTTGCAGATGTTCGAATGTCACAATTGTACTTACCAGTCCACGAGGAAATATAATCTGAAAAGGCATATGCTAGTACATAGAGAACCAAAAAAATTAGATATGTACAGTTGTAGTCAATGTGAATACCAAGCAAAAGGAAAAAAGGGCTTAAAAATGCATATACAGCTAGTTCACAAAGATTCTTTAATCCTTAATAGGGAAAGCGAAGAAAATGCATTAAAATGTCCAAACTGTACCTACATAACAATTGACAAATTCTTACTTAAGAAACATCTTATAATCCATAAAGACTCAAACAAGTTGCAGATGTTCGAATGTCACAGTTGTTCTTACCAGACCAAGCTCAAAAGCAACCTTAAAAAACATATGCTAGTGCATAGGAACCCTAAAGAATTAGAGATGTTCAAATGTAGTCATTGTAATTACCAAGGAAAACGAAAACAGGAATTAGAAATACATATGTTGGTTCACAAAGATCCTAGtgaagtgacaatgtacaaatgcaaCGAATGCTGTTATGAAACCAGACATAAGCGTTGCCTAAGAAAACATGTTTTGGTTCATCGAAGTAAAAATGAACTGGCAGTTAAAGAGTTAATACATCAATGTCCTCACTGCGCCTATATGTCAAGACAACGAGTGAAGCCCTTAGAAGAAATAGCGAATATTGTACAAAGTATTCTTCCAAGATCGAACTTAAATATCACAAGTAATCCTATGATATGTAATGCATGTAATGAGTTGGTAGAGAAATCCTATGGGTACAAATTGTTTTGTCTGGGAACAGATAACAAATTGTACACGGAAGAAAATATTCACTCTGGagtgttaaccaaaatgaagaaggAGACAGGGAATGAAAGTAACAACTGCTGTAGATTTTGTTCACAACCTgttgataaaaataatttcagaaaattaaataatctagATGCTGGTATGATGGAAGTATGTATTCCAAAATTGGATCCACCTCTTATGCAAAATGATATATTATGTGAAACGTGTTTGGATAACATACAAGTCCATTATAATTTTGTCGAAATGTGTTTAAAAGTAGAAGAAAGAATTAATATTTACTGTAAAGCCTATGGTAATGAAACCAATGGTGAAGTTGACTTACTACATATCCTTGAATTTTCACATACAGACAATTATATTGGCAAGCTTgaaattaaagaagaaaaattggaagaaaatgATTTGCCAGCTGGAGATATTTTAATGGAGATGGATGAGAACTGGCTGACAAAAGAAGAAATCCCCTTTAAAGATGAACCTGAAGTGTATGACACTCGTTTggAAGCACTCAAAGTTGAAAGCCAAGAGGCACCCAAACAAGCAGTCGATGAAATTACTTTGGAATGTACAGAACGTACTTACCTAaccaataataaacaatttgcaaGAAATGTTGGGCTTCATAAAGACACAAGTGATTTGCATATGTTCAAATGTCGCCTTTGTACTTACCAGTGCAAGTTGAGATATCACCTGATAAGACATGTGCTGGTACACAGGAATCCAGCAGAATTAGAGATGTTCAAGTGTCACCTTTGTACGTATCAGTCCAAGTTGAAATATCACCTGACAAGACATATGCTAGTCCACAAGGATCCAGCAGAATTAGACATGTTCAAATGTAATCAATGTAAATATCAAGCAAAACGAAAAAGGGACTTAAAAAGACATATTGTGTCACTTCACAGAGATTCATTCATCCTTACTAAGGAAAATGAAGAAATTACATGGGAATGTACAAAATGTACTTACTTAACAACGGATAAATACTTATTTGAAAAACATCTTATGGTTCATAGAGACTCAAAAGAGTTGCGGATGTTCAAATGTCACCTTTGTAATTACCAATCTAAGTTCAAAGGTCACCTGAAAAGACATATGCTAGTACACAGGAATCCAACAGAATTAGATATGTATAATTGCAGTCAATGTGAATATCAAGCAAGACGAAAAAGAAACTTATATGAACATGTTGCATTGGTTCACCAAGATTGCTTCTTCCTTACTAGGGGAAAGGAAAAGGCTAGATTAGAATGTATAAAATGTACCTACATAACGACAGAAAAATACTTACTTGAAAAACACCTTATGGTTCATGCAGACCCAAGCAAATTGCAGATGTTTAAATGTCACAATTGTACTTACCAGTCCAAGAAGAAATATTATCTGAAAAGGCATATGCTAGTACATAGAGATCCAAAAGAATTAGATATGTACAGCTGTAGTCAATGTGAATACCAGACAAAACGAAAAAAGGACCTAAAAACACATACACTGTCGGTTCACAAAGATTCTTTGATCCTTAATAGGGAAAGCACAGAAAATATATTAGAATGTCCAAACTGTACTTACCTAACAACTGACAAATTCTTATTTAAGAAACATCTTATGACCCATAAAGACTCAAATGAGTTGCAGATGTTCGAATGTCACAATTGTTCTCACCAGACCAAGCTCAAAAGCAACCTTATAAAACATATGCTAGTGCATAGAAACCCAAAAGAATTAGTGATGTTCAAATGTAGCCAATGTAAGTATCAAGGAAAACGAAAAAAGGAATTAGAAATACACATGTTGGTTCACAAAGATCCTAGtgaagtgacaatgtacaaatgcaaCGAATGCTGTTATGAAACTAAGCATAAGTCTTGCCTAAGAAAACATGTTTTGGTGCATTAA
Protein Sequence
MTDEKCTICRLCLRVVSDNSMKPLEEIANIVQSILPRLNLNIISNPMICSTCNELVQKSYEYKLFCLGTNKLYMEENIHPELLKEMKKETTNDSNNCCRSCSQPVNKNDLRKLGNVDAGMMEVFIPKLDPPLMQNDILCEMCLDNIQVHYNLVEMCSNVEERINIYCKAYANDTIGEVDLLDILEFSLNTDNYIDKLEIKEEKLEDTDLPAGDIFREMNENWLAKEEIPFKDESEVYDTHVDLEALKVESQQAPEQAVNEIALKRTERTYLTKNKQFFVRNLDFHNGTSNVHRFKCHICTYQCSFKYLLTRHNMLVHKNPAELDMFKCHICTYQSKLKYHLTKHMLVHRDPSELDMFKCSQCRYQAKRKRDLKRHIVSLHGDSFILTRENEENTLECTKCTYLTTDKYLFEKHLRVHIDLNELQMFECHNCTYQSTRKYNLKRHMLVHREPKKLDMYSCSQCEYQAKGKKGLKMHIQLVHKDSLILNRESEENALKCPNCTYITIDKFLLKKHLIIHKDSNKLQMFECHSCSYQTKLKSNLKKHMLVHRNPKELEMFKCSHCNYQGKRKQELEIHMLVHKDPSEVTMYKCNECCYETRHKRCLRKHVLVHRSKNELAVKELIHQCPHCAYMSRQRVKPLEEIANIVQSILPRSNLNITSNPMICNACNELVEKSYGYKLFCLGTDNKLYTEENIHSGVLTKMKKETGNESNNCCRFCSQPVDKNNFRKLNNLDAGMMEVCIPKLDPPLMQNDILCETCLDNIQVHYNFVEMCLKVEERINIYCKAYGNETNGEVDLLHILEFSHTDNYIGKLEIKEEKLEENDLPAGDILMEMDENWLTKEEIPFKDEPEVYDTRLEALKVESQEAPKQAVDEITLECTERTYLTNNKQFARNVGLHKDTSDLHMFKCRLCTYQCKLRYHLIRHVLVHRNPAELEMFKCHLCTYQSKLKYHLTRHMLVHKDPAELDMFKCNQCKYQAKRKRDLKRHIVSLHRDSFILTKENEEITWECTKCTYLTTDKYLFEKHLMVHRDSKELRMFKCHLCNYQSKFKGHLKRHMLVHRNPTELDMYNCSQCEYQARRKRNLYEHVALVHQDCFFLTRGKEKARLECIKCTYITTEKYLLEKHLMVHADPSKLQMFKCHNCTYQSKKKYYLKRHMLVHRDPKELDMYSCSQCEYQTKRKKDLKTHTLSVHKDSLILNRESTENILECPNCTYLTTDKFLFKKHLMTHKDSNELQMFECHNCSHQTKLKSNLIKHMLVHRNPKELVMFKCSQCKYQGKRKKELEIHMLVHKDPSEVTMYKCNECCYETKHKSCLRKHVLVH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-