Basic Information

Insect: Leptura quadrifasciata
Gene Symbol: ZNF143
Assembly: GCA_963675555.1
Location: OY776678.1:102529925-102551372[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0039 0.73 12.5 0.1 1 23 171 193 171 193 0.95

2 18 0.0079 1.5 11.6 0.9 2 23 200 221 200 221 0.98

3 18 6.6e-07 0.00012 24.4 1.0 1 23 227 249 227 249 0.98

4 18 0.0049 0.92 12.2 0.1 1 23 255 277 255 277 0.96

5 18 4.1e-06 0.00076 21.9 0.5 2 23 284 305 283 305 0.97

6 18 2.3e-05 0.0043 19.5 5.0 1 23 311 333 311 333 0.97

7 18 1.4e-05 0.0026 20.2 5.5 1 23 339 361 339 361 0.97

8 18 3.9e-05 0.0073 18.8 2.7 1 23 367 389 367 389 0.98

9 18 1.9e-06 0.00035 23.0 0.2 1 23 395 417 395 417 0.98

10 18 6.9e-05 0.013 18.0 8.1 1 23 423 445 423 445 0.98

11 18 7.6e-05 0.014 17.9 0.9 1 23 451 473 451 473 0.97

12 18 2.9e-05 0.0054 19.2 3.5 1 23 835 859 835 859 0.95

13 18 3.6e-07 6.6e-05 25.2 0.9 1 23 865 889 865 889 0.98

14 18 3e-05 0.0055 19.2 4.7 1 23 895 917 895 917 0.98

15 18 0.0064 1.2 11.8 0.2 1 23 923 947 923 947 0.95

16 18 5.2e-06 0.00096 21.6 0.3 1 23 953 977 953 977 0.97

17 18 0.0004 0.074 15.6 0.7 1 23 983 1007 983 1007 0.95

18 18 2.7 5.1e+02 3.6 4.2 1 23 1013 1036 1013 1036 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0039	0.73	12.5	0.1	1	23	171	193	171	193	0.95
2	18	0.0079	1.5	11.6	0.9	2	23	200	221	200	221	0.98
3	18	6.6e-07	0.00012	24.4	1.0	1	23	227	249	227	249	0.98
4	18	0.0049	0.92	12.2	0.1	1	23	255	277	255	277	0.96
5	18	4.1e-06	0.00076	21.9	0.5	2	23	284	305	283	305	0.97
6	18	2.3e-05	0.0043	19.5	5.0	1	23	311	333	311	333	0.97
7	18	1.4e-05	0.0026	20.2	5.5	1	23	339	361	339	361	0.97
8	18	3.9e-05	0.0073	18.8	2.7	1	23	367	389	367	389	0.98
9	18	1.9e-06	0.00035	23.0	0.2	1	23	395	417	395	417	0.98
10	18	6.9e-05	0.013	18.0	8.1	1	23	423	445	423	445	0.98
11	18	7.6e-05	0.014	17.9	0.9	1	23	451	473	451	473	0.97
12	18	2.9e-05	0.0054	19.2	3.5	1	23	835	859	835	859	0.95
13	18	3.6e-07	6.6e-05	25.2	0.9	1	23	865	889	865	889	0.98
14	18	3e-05	0.0055	19.2	4.7	1	23	895	917	895	917	0.98
15	18	0.0064	1.2	11.8	0.2	1	23	923	947	923	947	0.95
16	18	5.2e-06	0.00096	21.6	0.3	1	23	953	977	953	977	0.97
17	18	0.0004	0.074	15.6	0.7	1	23	983	1007	983	1007	0.95
18	18	2.7	5.1e+02	3.6	4.2	1	23	1013	1036	1013	1036	0.94

Sequence Information

Coding Sequence: atggaaCATGAGAAAAATAACTGGAACACATTTAACGCAAACATAAATTGTGACCAATCAAACAAGTATGATAAAACATGCAGAGCTTGCCTCACCGAAAATGATAATATGATTTCAATTTACCACCCAGAGATAAAAGATATGTTTACATTTTGTACTTCACTGGAGCTGAATAACGACGACAAATTGCCTGGTCTTATTTGCTGCCAATGCAGAACAGATTTATTGCGAGCCCACAATTTCAAAGATTTAtgtataaaatcaaataatatcctACAAGAACACATATCCCGATATAAAATTGATGATATCGAACTTAATTTAAATGAATTACTAAAAACAGATCTCTGTGATCCAAGTATAAACATAAGTTGTGATTTAGCAAAAGATGAAAGAAGTGTTATAGATATTGTAGATAAACAAATTAAGGAAATTATAGATGAACATATTAATAACTGTGATGAAGATAATAATAGTACTGCGAGtattcaatcattaaaagataatctttataaatgtaatatttgttCCGAGGCTTTTACCTTAGAAATAGATCTTGAAACTCATAAAATCGGCCACCCCAATGATGGTATTCCAAGATGTACACTGTGTAATAAACTATTTAATGATGCAAAGATTTTGAGGAGACATGTTCGAATCCACCTAAAAGCGAAACCGTTCCCATGTAACATGTGTAGTAAAAGTTTTTCAGAATCAGGAAGTTTAACCCGGCATATAAGAAAGCATAGAGGAGAAAAGAGGCACATTTGTTCAGCGTGCGGAAAAGGTTTCTATGAAGCTAATGTATTGGCTGTACATATGAGGATACACACTGGCGAAAAACCGATAACTTGTGATATTTGTAGCAAGAAATTTTCAGACCCAAACGGCCTAAGAAGTCACATGAAATCTCACACTGGTGAAAGAAACCACGTGTGTACCATTTGTAACAAGTCTTTTTCGCACTCCTTTGTGTTAAAGAAACACTTAAGGGTACACAGTGGAGAACGGCCCTTCATTTGTCATACTTGTGGAAAATCTTTCACCCAGAGCCATTACGTGAAAATTCACATGAGGCAACACACCGGAGAATTACCATATATGTGTATGATTTGCAAAAAGCGTTTTACGCAGCATAGTCAAATGGAAATTCACCTGAGAATCCACACTGGTATTAAACCATATATCTGTCAGGTTTGTGGGAAGACTTTTGCAAGGTCCGGTGATTTGGGTACCCACTTGAGGTCACACACAGGCGAGAAACCATTCTCTTGTACCCACTGTCATAAACAATATGCCACGTCAAGCCATTTAAAAGTTCACTTAAGGTCGCATACAGGTGAGCGGAACCACATGTGCGTTACGTGTGGAAAAAGATTTGTCGAAAGTCAAGGATTGAAAGCCCACGTACGAACCCATACGGaatttATTGACGTGTTCTCCACTTCTGTAAAGAATAATTGCCCCAAATTTACACTATCTGGCTTCAAATACCAACTCCCACCATTCATATTAAAACTAATCAAAATAAAGAGACAACTATACAGAGAAATAGAGGAAAATGAGGAACCTACACTGAAAACTAAGTATAACGAATTAGGTCAAGATATTCACAAGCTAGTTCTACAATACAAAACTTCTAAATGGCTAGAAGCATGTAAAGAAATTAACGATCTCAAAGGCAGGAAATATTGGCAATCAATAAAAAAACTCTCAAAATACAGAAAAGCTCAGCAATCACGTGACGTTAGGGAAAATGGCCAAATATATAAAACAGATCAAGAAAAGACGGGTGCATTCGccagattttacaagaaaatatttaccgaaaatgacgaTTTCCATGAGGAGCATAGGCAACACATAAACAATTGGTGCGAAGACTACACACAAAGCATTAATGATGACGAAGAAATAACCTTCATAGACGATAACGAATATTTTGGAATCTTGAAAACCACAGAAGTCTTCCCTCATAATATTCAACCACAAAATCAACAACCACTCaccaaaaAAGATTCTCCGAAAGAAGAAGTTTTTCAATATTATACAGATGTAAATGAGGCAGAAAATGTTGAAAAAGTGGATCAGAGAAATCAAGTGATTTTCTTAACAGTTCAATCTgaaaattttgttgataattCTACTATAAACGATACAATGGAAAACTTAGACGCCCCAGAAATTTCTGAAGATATAGAACATAATGGTTTATCGTCATTTGGATCTAATGTTACAGTTATCACTCTTGACGATGGTAGAATTTTGATGACACCATCCTTTGaagAAGACAATTTCGAGTCCATTGAACCTCATCTAATCTCAGATGAAAGTATTAACAAAGACAACGAATCTGAGGAGGAGGAATCAACACAAAACTCAAATGATGATGATACAAATTTGAAAATTGTACAAGTAGTAGGTAATTCTTCCCAAATGTATCAAATGGTATATTGCGATGTTGGATCGTCTACCCAACATACCGTAAAGAAAGAAAAATCATATGTATGTGTGCATGACGGATGTGGAAAAACATATACAAGTGCTCATcatttaaatGTTCATATGCGAAATCATTCCGGCAGCAAGCCATATGTATGTACTGAAGAGCGCTGTGACAAAACATTTTCCACAAATTATTCCCTTAAGGCACACATACGTACACACACAGGAGAGAAACCATATAATTGTGTAATATGCCAGAAATGTTTTAAAACTTGTGGGGACCTGCAGAAACACGTTAGGATACATACAGGCGAAAAACCATTCGTGTGCCCTATTGAGGGATGCGGCAGGTCATTTACTACGTCCAATATTAGAAAAGTTCATGTTAGATCTCATACAGGGGAACGACCATATTCATGTGATTATCCAAATTGTGGCAAAGCGTTCGCCTCatctacaaactacaaaaatcacATTCGGATACATTCTGGTGAAAAACCATATGCATGCAATGTCAAGGACTGTGGTAAGCGATTTACGGAATACTCCTCACTGTACAAACATAATTTAGTTCATCAACCGGACAGACCTTACACTTGTATATTTTGTGGACAAAAATTCAAGCAAGATTGTACAATGAATTTACATAAAAGGGTAAAACACAATGTGATAGTTGCCAATGATGGCAGAGAATTAGTTATTTTAAACTCAGATTTGGATATTGATGATTGA
Protein Sequence: MEHEKNNWNTFNANINCDQSNKYDKTCRACLTENDNMISIYHPEIKDMFTFCTSLELNNDDKLPGLICCQCRTDLLRAHNFKDLCIKSNNILQEHISRYKIDDIELNLNELLKTDLCDPSINISCDLAKDERSVIDIVDKQIKEIIDEHINNCDEDNNSTASIQSLKDNLYKCNICSEAFTLEIDLETHKIGHPNDGIPRCTLCNKLFNDAKILRRHVRIHLKAKPFPCNMCSKSFSESGSLTRHIRKHRGEKRHICSACGKGFYEANVLAVHMRIHTGEKPITCDICSKKFSDPNGLRSHMKSHTGERNHVCTICNKSFSHSFVLKKHLRVHSGERPFICHTCGKSFTQSHYVKIHMRQHTGELPYMCMICKKRFTQHSQMEIHLRIHTGIKPYICQVCGKTFARSGDLGTHLRSHTGEKPFSCTHCHKQYATSSHLKVHLRSHTGERNHMCVTCGKRFVESQGLKAHVRTHTEFIDVFSTSVKNNCPKFTLSGFKYQLPPFILKLIKIKRQLYREIEENEEPTLKTKYNELGQDIHKLVLQYKTSKWLEACKEINDLKGRKYWQSIKKLSKYRKAQQSRDVRENGQIYKTDQEKTGAFARFYKKIFTENDDFHEEHRQHINNWCEDYTQSINDDEEITFIDDNEYFGILKTTEVFPHNIQPQNQQPLTKKDSPKEEVFQYYTDVNEAENVEKVDQRNQVIFLTVQSENFVDNSTINDTMENLDAPEISEDIEHNGLSSFGSNVTVITLDDGRILMTPSFEEDNFESIEPHLISDESINKDNESEEEESTQNSNDDDTNLKIVQVVGNSSQMYQMVYCDVGSSTQHTVKKEKSYVCVHDGCGKTYTSAHHLNVHMRNHSGSKPYVCTEERCDKTFSTNYSLKAHIRTHTGEKPYNCVICQKCFKTCGDLQKHVRIHTGEKPFVCPIEGCGRSFTTSNIRKVHVRSHTGERPYSCDYPNCGKAFASSTNYKNHIRIHSGEKPYACNVKDCGKRFTEYSSLYKHNLVHQPDRPYTCIFCGQKFKQDCTMNLHKRVKHNVIVANDGRELVILNSDLDIDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -