Basic Information

Insect: Leptopilina heterotoma
Gene Symbol: zfh1
Assembly: GCA_015476425.1
Location: JABAIE010000022.1:985612-1187022[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.53 1.1e+02 5.1 0.3 3 23 360 382 360 382 0.87

2 13 0.42 88 5.4 0.7 5 22 573 590 569 593 0.85

3 13 4.4e-05 0.0093 17.9 0.2 2 23 608 630 607 630 0.96

4 13 0.015 3.1 10.0 0.7 1 23 645 669 645 669 0.93

5 13 0.0075 1.6 10.9 1.3 2 23 686 708 686 708 0.93

6 13 0.034 7.2 8.8 0.2 1 21 713 733 713 734 0.94

7 13 0.001 0.22 13.6 5.0 1 23 794 815 794 815 0.98

8 13 0.044 9.2 8.5 1.0 1 21 821 841 821 842 0.95

9 13 0.0007 0.15 14.2 2.3 1 23 858 880 858 880 0.98

10 13 0.085 18 7.6 0.6 1 23 885 910 885 910 0.96

11 13 0.0043 0.9 11.7 1.2 1 23 917 939 917 939 0.98

12 13 0.94 2e+02 4.3 1.2 1 23 950 975 950 975 0.94

13 13 0.00027 0.058 15.4 1.1 1 21 981 1001 981 1006 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.53	1.1e+02	5.1	0.3	3	23	360	382	360	382	0.87
2	13	0.42	88	5.4	0.7	5	22	573	590	569	593	0.85
3	13	4.4e-05	0.0093	17.9	0.2	2	23	608	630	607	630	0.96
4	13	0.015	3.1	10.0	0.7	1	23	645	669	645	669	0.93
5	13	0.0075	1.6	10.9	1.3	2	23	686	708	686	708	0.93
6	13	0.034	7.2	8.8	0.2	1	21	713	733	713	734	0.94
7	13	0.001	0.22	13.6	5.0	1	23	794	815	794	815	0.98
8	13	0.044	9.2	8.5	1.0	1	21	821	841	821	842	0.95
9	13	0.0007	0.15	14.2	2.3	1	23	858	880	858	880	0.98
10	13	0.085	18	7.6	0.6	1	23	885	910	885	910	0.96
11	13	0.0043	0.9	11.7	1.2	1	23	917	939	917	939	0.98
12	13	0.94	2e+02	4.3	1.2	1	23	950	975	950	975	0.94
13	13	0.00027	0.058	15.4	1.1	1	21	981	1001	981	1006	0.94

Sequence Information

Coding Sequence: ATGATGGAGGCATACGATGATGACGATGACGACACACACTTTTGCATTAAGTGCAATTCCACAATCCATGGTTTGGAGAATTACGTTCGTCACCGACAATCCGGATGTCGTGTTAAAACAGAATCACATGATGCACCTGCAACTCCAACGACAGTATCCTATCCAGAAATTTTAAACGCTGACGCTTTCTTCAGTTCTCTGGAGCTACAAAGCAGTTCGAAATCAAATTCACGTCGAATGACTTCAAGTGATCGTTCAAGAAAATCCGGAAGAAATGAGGATCGTAAAAAGAAGAATCAAAAGGACAAAAGTCCGGAAGACTCTTCAAAGGATAAATTACACAATCTTCTGCCAGTCGTAACTGATCTTGATGATCCGACAGATCATCTTGGAATTCCGTCATTGGTCGGATTTCCCGATATAGTCTCAACCAGTAAACCATCAACTTCCGTCAAAATATGCCTGGTTTCCTCAGGAAAAATAGAAGCATCTGAGTTTCATGGAAAACAAGATTCATTGGAGAGTGTAATTTCTAAGCAGCTGGATAGTAAACGGAATGATTCGCAAAGATTAGACCAAGATCATCAAAGTTGGTTGGATGATTCCCTTTTGGTTGATTTGGTGGTAAATCCTGTCAATAAGGACACTTCGAACTCGAGTCTGAGTAGATTTGAAGATTTCGACTTTCAGCAGGAGGAGGAAATGGAGGAAGAGAGTGGGGAAGATTATATAGAAGATGATGAATCATTCTCGGAATCAGATGATGAAGATCGTAGTTATCCTCCTGTTAGTCACACGGGGGGAAAGTGGAAACCAGGCAGCATATCACAAACCATATCACATGATCTTCATGAAGATGATATAGAAATTACAAATGAAGATGAAAATGAACATAATCATCATCATCATCATCCTCCGCCGTCGCACACTGGTGGCAAGTGGAAGCCTACCGAAAGTAATTCTATGGATGATATAGAGTTGATGGAGCACAAAATGGATATAGACCAACCACCGCTGGGACATACTAGAGGAAAATGGGTACCCGGAGCACGTGCTGATATAAGCTCAGGATATTGGTGCAGTCCTTGTGGTAGAAATCTGGCTTCACGCGTACTCTACAACAGGCACCTGCGCTCTGACCTTCACGCCAGGAGAAACATGCAGGAAATCGATGGTGTTGTACAATTTCCTCAATCTGTCAACCGAAAAATGAAGCTTCAAGAGCCGAGAGAAAATAATGAAGAGAATTCGAATGACGGGCATCAGATTGTCAAGAAACAGATTCGCAAAAGGGAAAAAGAGATTTTGACTTGTGAGATGTGTTGCGCTCGAGTGCGTCGCCCACAAATGGGAAAGCATCTACTTTCCCATTATCACTGCCGAGTAGCAGGTGCAAACCCTTTTAGAGCAAAAGCCCAGCAATTCCTTTTGGAGAACATGGAGAACGTTGTACGACAATGTCCTTTTCAATGTAGTCCCTGTAAATTTTATTGTAACACAGAAGACACCTTTTTATTACATTGGCGATCTTCCTTTCACCTGTCGATTATCAGCAAGATTGATGGAAACTTTAAATGTGCTCCATGTGCCTTTTGGTGTGATGAAAACTCAAGTATGGAGTCACATCTTTTGAGTTCTTGTCATCGAGATTTGATTGCTATGATGAATGGTTCAATTCCTACTGTCATATCAAGACAAAGAAGCCTAATATGCATAACTTGCGAACAAACATTTAGATATAACATAGAATTATGCCAACATGCAAAAAGTACTGGACATGAGGTTAATTTCACAGCTACTGACGAATACCAAAAAAGAATTAGATGTCAACTCTGTGATATCGTATTTAGATCATTAGTGGCACTACAAAGACATCAATTAACATTTCACAAGTCAGAACCTAATAAAGTTCCAAAGATGGATCTTGTTCCGTACTATTGCTCTTTTTGTTCTTTGAGTTTCAAGACAACAGAAGAAGCTATTTTGCACCGAAGAACTTTGGCCCACAAAGAAATAGTCAAATCGACGAAAGCTGATAATCCCTCGATTTCTAGAGAATGTCTTAATTGCAATAAACATCTGTCCAGCCTTTCAGAATTAAGAACTCATCTTCTCGAGCTACATCCAGAACTTTGCTTCAGGTGTCCAAAATGTGCTAAAATTTTTGCACTATCTCAAGATGTCTCAAGACATACCAAAGAAGGTGAATGCAATCCGCAAGAAATTCCAAATGTTTTTAACGACAATGTCGAATGGAAATGTAGCATATGTCCTTTTGCAACTGAGTTGCAGTCAGAATTCATTTTTCACGAAGCGCTACATGCGGGACCTGTTGAACCTAAAATTGGAGAAGCCGGAAGTAGTAGACCTGCGGTTAATTATCAGTGTACTCTCTGCAAAAAGTGTTACTCGAAAACAACTTTGAGAAATCACATCAGGGGTCACACTGGCGAACGACCATTTCCATGCAGCAAGTGCAGTCTTAGTTTTTTGAGACGAAATGACCTGAACACACATCGTAAAAATTGCAGGCAAATTCCTCAACATGAAAAATCAGATCGTCAAAGAAACTTTTCGTGTGCTGAATGCAGTTCTGCTTTCTTCACCAAGCATGCACTTCGACAGCATATGATGAGGCATAATGGAAAGCAGTATAAATGCGAATTTCCTGGCTGTATTACTTCTTTACGTACTGAAGCTGAATTAAAACATCATCAGATGAGAGTTCACGGAACTCCGGAGCAAATCTATCCATGCAGTTACTGTAGTTATACAGCTAAATTTCGCTGGCAACTAGCAAGGCATGAAAAGAAACACAGGCCTCCAGATGACGTGAGTGATAAGCAGCATGCTTGTCCATTCGACGGCTGTCAATTTCGGGCAATTTCTACTGGACATATCAAACGCCACGTCCGTACTATTCACACAAATGAGAAGCCCTTCAGGTGTCGCTACTGCACCTATGCCAGTAGCACTCAGGAGAATCTAAGGAAACATATTCTTTCAACGAGTCTGCACGTTGGCAAAACGATTTACGAGTGCGATGCTTGTAAGGAAAAAGGTTTGGAGCCATACTGCACTAACTTTGCCAAAGAACTTAAAGCTCATTTACTTGAAGAACATTCTGACGAATTTCCATCAATGGATGTTGTTAATAACTATGTGACTAATTTTTTTGACTTTGTACAAGAATGA
Protein Sequence: MMEAYDDDDDDTHFCIKCNSTIHGLENYVRHRQSGCRVKTESHDAPATPTTVSYPEILNADAFFSSLELQSSSKSNSRRMTSSDRSRKSGRNEDRKKKNQKDKSPEDSSKDKLHNLLPVVTDLDDPTDHLGIPSLVGFPDIVSTSKPSTSVKICLVSSGKIEASEFHGKQDSLESVISKQLDSKRNDSQRLDQDHQSWLDDSLLVDLVVNPVNKDTSNSSLSRFEDFDFQQEEEMEEESGEDYIEDDESFSESDDEDRSYPPVSHTGGKWKPGSISQTISHDLHEDDIEITNEDENEHNHHHHHPPPSHTGGKWKPTESNSMDDIELMEHKMDIDQPPLGHTRGKWVPGARADISSGYWCSPCGRNLASRVLYNRHLRSDLHARRNMQEIDGVVQFPQSVNRKMKLQEPRENNEENSNDGHQIVKKQIRKREKEILTCEMCCARVRRPQMGKHLLSHYHCRVAGANPFRAKAQQFLLENMENVVRQCPFQCSPCKFYCNTEDTFLLHWRSSFHLSIISKIDGNFKCAPCAFWCDENSSMESHLLSSCHRDLIAMMNGSIPTVISRQRSLICITCEQTFRYNIELCQHAKSTGHEVNFTATDEYQKRIRCQLCDIVFRSLVALQRHQLTFHKSEPNKVPKMDLVPYYCSFCSLSFKTTEEAILHRRTLAHKEIVKSTKADNPSISRECLNCNKHLSSLSELRTHLLELHPELCFRCPKCAKIFALSQDVSRHTKEGECNPQEIPNVFNDNVEWKCSICPFATELQSEFIFHEALHAGPVEPKIGEAGSSRPAVNYQCTLCKKCYSKTTLRNHIRGHTGERPFPCSKCSLSFLRRNDLNTHRKNCRQIPQHEKSDRQRNFSCAECSSAFFTKHALRQHMMRHNGKQYKCEFPGCITSLRTEAELKHHQMRVHGTPEQIYPCSYCSYTAKFRWQLARHEKKHRPPDDVSDKQHACPFDGCQFRAISTGHIKRHVRTIHTNEKPFRCRYCTYASSTQENLRKHILSTSLHVGKTIYECDACKEKGLEPYCTNFAKELKAHLLEEHSDEFPSMDVVNNYVTNFFDFVQE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00880011;
90% Identity: iTF_00881631;
80% Identity: -