Basic Information

Insect: Leptopilina drosophilae
Gene Symbol: prdm10
Assembly: GCA_032873175.1
Location: CM065483.1:5788668-5794943[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00041 0.083 14.7 0.1 2 23 484 505 483 505 0.96

2 14 1.2e-07 2.4e-05 25.8 2.8 1 23 539 561 539 561 0.98

3 14 0.005 1 11.3 1.5 1 21 569 589 569 590 0.95

4 14 0.014 2.8 9.9 0.7 2 23 614 635 613 635 0.95

5 14 0.00026 0.052 15.3 0.0 2 23 648 669 647 669 0.95

6 14 0.0093 1.9 10.4 3.8 1 23 686 708 686 708 0.91

7 14 0.0061 1.2 11.0 2.6 2 23 717 738 716 738 0.96

8 14 0.13 27 6.8 0.1 1 23 745 767 745 767 0.96

9 14 0.001 0.2 13.5 5.1 1 23 774 796 774 797 0.96

10 14 0.0025 0.52 12.2 3.1 1 23 802 824 802 824 0.98

11 14 1.6e-06 0.00032 22.3 1.5 1 23 830 853 830 853 0.96

12 14 0.0017 0.35 12.7 1.7 1 23 886 909 886 909 0.97

13 14 0.00013 0.027 16.2 2.4 1 23 931 954 931 954 0.97

14 14 0.0039 0.79 11.6 3.4 3 23 992 1013 992 1013 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00041	0.083	14.7	0.1	2	23	484	505	483	505	0.96
2	14	1.2e-07	2.4e-05	25.8	2.8	1	23	539	561	539	561	0.98
3	14	0.005	1	11.3	1.5	1	21	569	589	569	590	0.95
4	14	0.014	2.8	9.9	0.7	2	23	614	635	613	635	0.95
5	14	0.00026	0.052	15.3	0.0	2	23	648	669	647	669	0.95
6	14	0.0093	1.9	10.4	3.8	1	23	686	708	686	708	0.91
7	14	0.0061	1.2	11.0	2.6	2	23	717	738	716	738	0.96
8	14	0.13	27	6.8	0.1	1	23	745	767	745	767	0.96
9	14	0.001	0.2	13.5	5.1	1	23	774	796	774	797	0.96
10	14	0.0025	0.52	12.2	3.1	1	23	802	824	802	824	0.98
11	14	1.6e-06	0.00032	22.3	1.5	1	23	830	853	830	853	0.96
12	14	0.0017	0.35	12.7	1.7	1	23	886	909	886	909	0.97
13	14	0.00013	0.027	16.2	2.4	1	23	931	954	931	954	0.97
14	14	0.0039	0.79	11.6	3.4	3	23	992	1013	992	1013	0.98

Sequence Information

Coding Sequence: atggACCCAAGGGCCCCTCCCGAAGGGGCCCCTGGCGATAATCTGGAGATGGCATCAATTGAAAAAACATCCGACGAAACGTGGTCGTCCGACAATAATGTACCATCGCCTCTTTGTGAACAGCGCAAAAAGATGAACAACAAATTACTCTTTCTAACGgTCGAGTATGTTGAGGATCAAACGCGCGACTACGCTCGTATGTTTTCGGTCTACGAGCCAGTTTCCTATTCACCTAGAGCATCATCGCCACTCTCTGAATTCGAACACCGTGTAAGTCCACACGATCCAAATATGAGTTCAGCCGCAAGATATTCACCGACTCCTGTTCAATTACCACCATCGCCATTTCAAAATTCCGTTGTTGTCCTAGAAAATTCCCCATCATCATCACTAAACTCATCATCAGAAACAAATACAAGAACAGACATCAATTTTGTCACCGAATTAAACGATCATCAAAATACTTCGCCAAGCATTCCACAAAATGAGAATACAACTGATTTTGTTGAGTCAAACAGTGAAGAAGGCCTTGTGCCTGGAAATGAATTGATTCTCATGCAAAGTGGAAATTCCGAATTAGAACCATCCGCACCACCATTGATGTTAACCGGTTCTGATTTTGCATTGACTCGCGATTTTCTTGTCATGCACGATGATCAAATAAGTGTtatgaattcatttaaaacggaaaatttagaaataaacgAAACCTACATTCCAAGTCCAATACAAACACTCAATTCAAATGAAGATATCGATTTGTGTTCAACAGTTGAATCTGACAAGGTTCTAAATACAATGAAAATTGTTGACAATCTTTTAGAATCGAAAGATGAGGAGAcgccaattaaaaaaattgttcgtcGTTCTAAACGACAGATAAATGATAAAAAGACTTATTGGTGTACAGAGTGTGATGCAATTTGTGCTGATGAAGATGGTTGTACGTCGCATAATGTTCAGACAATTGCCGATCAACCAGTTCCTTCGCGAGCAATCGCAACACTTCCTAGTtcttatttatcaattaataaattaaattcaaatgatGTAACACAGCAGGAATTTGGTGTTTTTGCGAAGAAAATTATTCGTAAACGAACACAATTTGGTCCAATTGAAGGTATTTTGTGTGCCTATGATGGCACTCCGTTTACTAACGTCTTACCATTATTGTTCGAAAATGAAGACGGCGATTTCTTCAAAGTCGATGTTTCCAATGAGAATACATCAAATTGGATGCGTTTCGTTCGTCCAGCGTTGTCTTATAAAGAtcagaatttaatgatttgccAGCAAAATGAAGGCATTATGTTTCTCACTACAAGGGATATTTTACCAAAAGAGGAATTGAGAGCCGGTCCAAATCCAGAGTACGCCAAGAAGcggaatttgaaaattctcgagGCTGATTCAGAGAATGCAAACGaAACTAGCTCTGATTCGTGGCCTTGTTTCGAATGTAACCGTCTCTTCCCAACTTCAGGCACCTTACAAAGTCACCTGAATGTCCACGATAATCCTCGTAGTGAAACAAAAGCCAGAAGTAAACGCAGGAAGCTTCACATCGCTTCCAAtAAACTATTTAAAGTCGTCAATGATCAGAAAATTCTCTACTCCTGTCCACATTGTTCGAAAGTATTTTCGCGTAGTTACAGCCTAAAACGTCACTTATTAATACATCCAAATAATAAGACAACACATTACGAATGTTCTAAATGTGGTGAAAATTTCCTATATCCAAATAATCTTTGTCGAcataagaaaatttgtcaaaatgatAATGAGACTGACAACAAGAAGAAGGGAAAGGAAAATTCTGGTCAAAATTCCGAATGGAAATGTACAGTGTGCAATTTGACATTCAATAAAGAATCATTGTTTGATCTACACAAAATATCTCACAATGTGAATAGTTTTGAGAATGGATGTAAATTTGTCGTTTGTCCCGAGTGTGGggtgaaatttgaaaaacaaaacgAGCTTATTAAACATGTTTCTGAACATGGAAAATtaccaatgaaaaaaataacaaacgcCACTACCTCGGCTACCTATAAATGCTCAATGTGCTATAAACGTTTTGCCACTAAAGTTCGACTCCAACAACATTGTTTAGTCCACGGCGCTGAGGACCAAAAACCACTGCCATGCAATATTTGCTTTAAACGATTTATGAATAATTCGGCACTCTCTTGTCATCTAAAGACACATAGAAaAGAGAAGCAAATGTTCGAATGTCCAATGTGTAAAGTacttttcgatcaaattttGATGCTTAAAGAACATGTCGAGTCGCATAGAAATCAGGACGATACATTCACTTGCCCTCACTGCCAgcgaaattttaccaaatattCAGTTATTCGAAAACACATTAGAGCTCATCATTGTGAACGAAAACATAAATGTACCTTTTGCGTGAAACGTTTTCCCACTGTCGATAAATTACGAATGCATTTACTACGCCATTCAGATCACAGAGAATTTCAATGCGCTATTTGTGGAAAACGATTCAAAAGAAAGGACAAACTAAAGGAACACGTGACGAGAATGCATAATTCTCAAAAACCAAATAAAGAAGCAACGTCGCCAATTAatcaagttaaaaaatttgtgcCAAAGGTCAATCCAACCGAGTACGATCGATTTGTATACAAATGTCATCAATGTTTGGTTGGTTTTAAAAGACGAGGTATGCTCGTTAATCATCTGGCAAAAAGACATCCGGATGTTCCGCCAGAATCTGTACCTGAACtgaatttaccaattttaagaCAGACGAGGGATTATTATTGTCAGTATTGTGAAAAGGTTTACAAGAGTAGTAGCAAACGAAAAGCACACATTATGAAAAATCATCCTGGTGCTGCATTGCCACCGAGTAATCGTCATAAGGAAACGGACATTCCCGGCTTGCCGAATTCTACTTTTAGTCAAACTGTGGGAAGTGTTACGACAACGCCCCAAGGATGCCAATGGTGTCATAAACAATATGCCAGTAAAgCGAAATTACTGCAACATCAGCGCAAAAAACATTCGTCATTAATGGAGCCAGCGGATCAGGTTCCAAGACATCGAAATCGTCCGATTCATAATCAAAATGACGAATTAATTTTGAGTAATATTAACTTTGTAATGGctaataatgttaatttaatgaACGATGAATTCGACTCGATTGGACAGCAATTTGTCCGCATGCGCGATATACGCTGA
Protein Sequence: MDPRAPPEGAPGDNLEMASIEKTSDETWSSDNNVPSPLCEQRKKMNNKLLFLTVEYVEDQTRDYARMFSVYEPVSYSPRASSPLSEFEHRVSPHDPNMSSAARYSPTPVQLPPSPFQNSVVVLENSPSSSLNSSSETNTRTDINFVTELNDHQNTSPSIPQNENTTDFVESNSEEGLVPGNELILMQSGNSELEPSAPPLMLTGSDFALTRDFLVMHDDQISVMNSFKTENLEINETYIPSPIQTLNSNEDIDLCSTVESDKVLNTMKIVDNLLESKDEETPIKKIVRRSKRQINDKKTYWCTECDAICADEDGCTSHNVQTIADQPVPSRAIATLPSSYLSINKLNSNDVTQQEFGVFAKKIIRKRTQFGPIEGILCAYDGTPFTNVLPLLFENEDGDFFKVDVSNENTSNWMRFVRPALSYKDQNLMICQQNEGIMFLTTRDILPKEELRAGPNPEYAKKRNLKILEADSENANETSSDSWPCFECNRLFPTSGTLQSHLNVHDNPRSETKARSKRRKLHIASNKLFKVVNDQKILYSCPHCSKVFSRSYSLKRHLLIHPNNKTTHYECSKCGENFLYPNNLCRHKKICQNDNETDNKKKGKENSGQNSEWKCTVCNLTFNKESLFDLHKISHNVNSFENGCKFVVCPECGVKFEKQNELIKHVSEHGKLPMKKITNATTSATYKCSMCYKRFATKVRLQQHCLVHGAEDQKPLPCNICFKRFMNNSALSCHLKTHRKEKQMFECPMCKVLFDQILMLKEHVESHRNQDDTFTCPHCQRNFTKYSVIRKHIRAHHCERKHKCTFCVKRFPTVDKLRMHLLRHSDHREFQCAICGKRFKRKDKLKEHVTRMHNSQKPNKEATSPINQVKKFVPKVNPTEYDRFVYKCHQCLVGFKRRGMLVNHLAKRHPDVPPESVPELNLPILRQTRDYYCQYCEKVYKSSSKRKAHIMKNHPGAALPPSNRHKETDIPGLPNSTFSQTVGSVTTTPQGCQWCHKQYASKAKLLQHQRKKHSSLMEPADQVPRHRNRPIHNQNDELILSNINFVMANNVNLMNDEFDSIGQQFVRMRDIR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00676996;
90% Identity: iTF_00882410;
80% Identity: -