Basic Information

Insect: Leptopilina clavipes
Gene Symbol: ZEB2
Assembly: GCA_001855655.1
Location: JUFY01026932.1:17817-22376[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0081 0.84 10.7 0.3 1 20 407 426 407 427 0.95

2 18 0.0039 0.4 11.8 0.0 2 23 432 454 432 454 0.94

3 18 0.15 15 6.8 2.4 1 23 459 482 459 482 0.97

4 18 1.7e-05 0.0018 19.2 0.1 1 23 488 511 488 511 0.94

5 18 0.045 4.7 8.4 5.0 1 23 518 540 518 540 0.98

6 18 8.2e-06 0.00084 20.2 0.3 2 23 546 567 545 567 0.97

7 18 3.3e-06 0.00034 21.4 2.0 1 23 573 595 573 595 0.99

8 18 4.6e-07 4.7e-05 24.1 0.2 1 23 601 623 601 623 0.98

9 18 0.47 48 5.2 0.9 2 23 811 833 810 833 0.96

10 18 1.4e-05 0.0014 19.5 1.2 1 23 839 862 839 862 0.98

11 18 0.23 24 6.2 0.1 2 23 868 890 867 890 0.95

12 18 0.00013 0.013 16.4 0.1 1 23 895 917 895 917 0.97

13 18 0.021 2.2 9.4 0.8 1 23 923 946 923 946 0.92

14 18 0.00017 0.018 16.0 6.6 1 23 962 985 962 985 0.96

15 18 0.001 0.11 13.6 0.1 1 23 996 1018 996 1018 0.96

16 18 0.015 1.5 10.0 3.6 1 23 1024 1046 1024 1046 0.95

17 18 1.1e-06 0.00011 22.9 1.1 1 23 1052 1074 1052 1074 0.98

18 18 0.58 60 4.9 1.2 1 21 1080 1100 1080 1101 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0081	0.84	10.7	0.3	1	20	407	426	407	427	0.95
2	18	0.0039	0.4	11.8	0.0	2	23	432	454	432	454	0.94
3	18	0.15	15	6.8	2.4	1	23	459	482	459	482	0.97
4	18	1.7e-05	0.0018	19.2	0.1	1	23	488	511	488	511	0.94
5	18	0.045	4.7	8.4	5.0	1	23	518	540	518	540	0.98
6	18	8.2e-06	0.00084	20.2	0.3	2	23	546	567	545	567	0.97
7	18	3.3e-06	0.00034	21.4	2.0	1	23	573	595	573	595	0.99
8	18	4.6e-07	4.7e-05	24.1	0.2	1	23	601	623	601	623	0.98
9	18	0.47	48	5.2	0.9	2	23	811	833	810	833	0.96
10	18	1.4e-05	0.0014	19.5	1.2	1	23	839	862	839	862	0.98
11	18	0.23	24	6.2	0.1	2	23	868	890	867	890	0.95
12	18	0.00013	0.013	16.4	0.1	1	23	895	917	895	917	0.97
13	18	0.021	2.2	9.4	0.8	1	23	923	946	923	946	0.92
14	18	0.00017	0.018	16.0	6.6	1	23	962	985	962	985	0.96
15	18	0.001	0.11	13.6	0.1	1	23	996	1018	996	1018	0.96
16	18	0.015	1.5	10.0	3.6	1	23	1024	1046	1024	1046	0.95
17	18	1.1e-06	0.00011	22.9	1.1	1	23	1052	1074	1052	1074	0.98
18	18	0.58	60	4.9	1.2	1	21	1080	1100	1080	1101	0.92

Sequence Information

Coding Sequence: ATGCAAAATaacattcttttcttttttttttgttttagggAAACtggcaagaaaaaaaaacaaatgagtGCAGCACAATTAAAGGCATTGAAGAAATTGctttctcgaaaaaaaaggaaaagtaaAAGATGGAATAAAGTgacatcaaaaaataaaaaagaaagttttcgACTTtatcagaaaagaaaaaaagaattggaaaatgaaattgccaattcgaaaaaaattcaagacatGAAGAAAATGGCGAAGACTGAAATTGTCACTGAATCAAAACAAGTTTTACGAGTAAAATCCCTCGTCGAATTGGaagattcaataaaaaaacaaaatttacccACATTACCAAACTCTTATGCTGAACGAACATTACTGCGAATTATTAATCCAAAATCACTACCAACTGAGGAAAAGAAGTTTCTCGTCGCATTAAATtcaggagaaaaatttttaggttcaACTGAAGCaccaaagaaaatatttattattcgtaAAGCGAATTCAGAAAATTCCAAaccaagaaaatttgtttcgaaGGAATTTCCAGCGGGTGAACAATTAAAAGcaccgaatttaattttacatcagGCGAATTTGATTTCATCGGATGAAAATTTAGTGGTGATGGATAATTCAAAGGAAGGATCATCCAAATATCAACAtttgaatcgaaaaaaagGACCAACACCGTCAACTTCAAAAGCGAGTAAAGTTGTAAATCAAAAACGAGTTATTAGAAAGGAAATGATTTTATTGGAAGAGTTTCGTGACACAGGGACTCCGGAGCCTCAAATGTTACAAGATCCGATTGATATTACTGGTACGATCTCGCCGAAACTTGAGGGTGAAACTGAAAAGGATGAAATTTGCCCTGAAACTGCAAATCAAActgtgaagaaattaaataatcctAAAGAAGCTACTTCGATTGttgattttaagaaaactgaTGAACTTCCGTCAACTTCCTTTCAATTTGATACGATTTCAAGTTTACCGTCAAACTCAAAACCTTCTAAAAATAATGCAGCAATTTCGAAAACACTTGAATCGACACCAGGCTTTTCGAATTTAACAGCCGATGAGAAATTGTCACAATCTCAACAATGTTTAGAATTTCTGAATGACCTGATTTTTGCAGATCTGGACAATTCAATGATGGAAATAACGGAGGacagtaaaaatttcacaacTTCTGAATTGGATGTGGATGAAAATTATCCTTGTGCACATTGCAATCGGGAATATAATTCATACACGGATCTCGTGAAGCATTGGATTGACTTGAAAAACGTTTGTGAATTATGCGATGTAGTTTTTCCGTTTCCTTTCTTATTGCAAATGCACATGCAGGACGTTCACAACATCAAGGGCTACAAATGCgcaaattgtaattatttccaTAGCAATTTGTGGAATCTAAAAATTCATCGTTCACGTGGCCACTGTCATGAGTATAAATATCCTTGCGAGAATTGCGACCGTGCTTTCAACAATTCCGATTCTTTACAATTACACATTGATCAAGATCACAAAACACCCAAGCAAAAATTCACCTGTAAACAGTGTGGTAAAATTTGTGTTACGCGAGCAATATATTGTCGTCATTTACAATCACacagaataaagaaaattgtttgcgaatattgtggcaaaaaatttgacatacAATCGGGACTTAAGAATCATTTGCGTCAGCATACTGGCGAGAAACCTTATAAATGCAGTATTTGCTCAAAGACATTCGCCAAGAGTAATACATTGCGACAACATTTATTGACACACTCCGGCAAGCGGCCATACGTTTGTGACATTTGCGGAAAAACATTCACGCAAAAACCCGGATTGTCCGCACATCGAAAAATTCATCCCGGTCAATTGCCTCAACAGCAAtgtgtttttattaatgatattCTCAAGGATTTGCCTGATGCTGCTTTAGAAAATTCGGGACCAAACAGCGAATCccaagaaattgaaaaagaactCAAGGAAGACGATGTAGAACAAGTTGAAAACAATactaatggaaataaaaaagcagttgaagaaaataaagtcAATTCAAGGGAAAAGGAGAATCTTCTTAATTcgattgaagaaaatttaccgGAGGCAAATACAATTGAAGCTAATGTTATGGAAATGGTTACAAATGAAGCAAACATCCTCGAAATAGTTGAAAACGAAGCAAACATCTTGCAAATGAATACTAATGATGCAAATATCTTGAAAATAGTCgagaatgataataatttggaagatatTTTCGagaatgatttaaataatgtcattcaaaaagaaatcgaAGATCCTGCCAACAATAAACACAATGTCAATAAGGTTGAACTTACAATTGAGGATTACAAGATCAAACTTGAAGACAAAACGGAAAAAGTGgatgaaaaATTCGAAAGCAGTGGTGAAAAATCGTGCGAATTTTGCGAAGAGAAATTCCACTTTGTCACGAGATTAGTGGCGCATTTACGAATTGCACACGGAATTCTAAGGCCCTTCAAGTGTGATAATTGTGACAAAACATATCCCCAACAATTTATGTTGAATGCCCACGTGAAAAAATCGCATACACCAAAAATAGTGCCTTGCAATCAATGTGATTTTATGGGTGTATCAAAGGCGGACGTTGAACGTCACAGCAAAAAATTGCACAAAGAAGTGAAATTCATTTGTGAAATTTGCAGCGAAGTCTTTAATCGTGAAGAGGATTTAATGACACACACGGCGATGCATGAATTTATGCAATTTCATCAATGCAACGCTTGCGGTGGTACATTCGATGATCTTTACAGTCTCAGGGAGCACAATCAACTTTATCATTATAATCCAAATTTAGGAATACAAAATGAGGAGAATTCACTTGAACATAAATGCGATATTTGCGGGAAAACTTATAAATATCGTTCAATGTTGAAGCAGCATAAAATAAAGTGTCATCCGGATACAGTCACCGTTGAGAGGCGACGATATCTTTGTGCGCTTTGCGGCAAGGAGCTAAAAACAGCAAAGGGCTTGGAAATTCACACGAGATCACACACAGGTGAAAAACCCTATACCTGTGAGGTTTGTGGCAAATGTTTCGCGTGCGAAACACTTTTAAGGACCCATAGCGTGACACACACTGGCGAACGGAAATATTCCTGTGATCAATGCGGTAAAGCTTTTACACAGAGATCAACACTCGTTGTTCATAAAAGGTACCACAGTGGCGAAAGACCATATTTGTGCCCTCGTTGTTGCAAGGGCTTTGTTACAAGAACTGTACTTAATACTCATTTAAAATCATGTCgttaa
Protein Sequence: MQNNILFFFFCFRETGKKKKQMSAAQLKALKKLLSRKKRKSKRWNKVTSKNKKESFRLYQKRKKELENEIANSKKIQDMKKMAKTEIVTESKQVLRVKSLVELEDSIKKQNLPTLPNSYAERTLLRIINPKSLPTEEKKFLVALNSGEKFLGSTEAPKKIFIIRKANSENSKPRKFVSKEFPAGEQLKAPNLILHQANLISSDENLVVMDNSKEGSSKYQHLNRKKGPTPSTSKASKVVNQKRVIRKEMILLEEFRDTGTPEPQMLQDPIDITGTISPKLEGETEKDEICPETANQTVKKLNNPKEATSIVDFKKTDELPSTSFQFDTISSLPSNSKPSKNNAAISKTLESTPGFSNLTADEKLSQSQQCLEFLNDLIFADLDNSMMEITEDSKNFTTSELDVDENYPCAHCNREYNSYTDLVKHWIDLKNVCELCDVVFPFPFLLQMHMQDVHNIKGYKCANCNYFHSNLWNLKIHRSRGHCHEYKYPCENCDRAFNNSDSLQLHIDQDHKTPKQKFTCKQCGKICVTRAIYCRHLQSHRIKKIVCEYCGKKFDIQSGLKNHLRQHTGEKPYKCSICSKTFAKSNTLRQHLLTHSGKRPYVCDICGKTFTQKPGLSAHRKIHPGQLPQQQCVFINDILKDLPDAALENSGPNSESQEIEKELKEDDVEQVENNTNGNKKAVEENKVNSREKENLLNSIEENLPEANTIEANVMEMVTNEANILEIVENEANILQMNTNDANILKIVENDNNLEDIFENDLNNVIQKEIEDPANNKHNVNKVELTIEDYKIKLEDKTEKVDEKFESSGEKSCEFCEEKFHFVTRLVAHLRIAHGILRPFKCDNCDKTYPQQFMLNAHVKKSHTPKIVPCNQCDFMGVSKADVERHSKKLHKEVKFICEICSEVFNREEDLMTHTAMHEFMQFHQCNACGGTFDDLYSLREHNQLYHYNPNLGIQNEENSLEHKCDICGKTYKYRSMLKQHKIKCHPDTVTVERRRYLCALCGKELKTAKGLEIHTRSHTGEKPYTCEVCGKCFACETLLRTHSVTHTGERKYSCDQCGKAFTQRSTLVVHKRYHSGERPYLCPRCCKGFVTRTVLNTHLKSCR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -