Basic Information

Insect: Leptomastidea abnormis
Gene Symbol: MED25
Assembly: GCA_030522805.1
Location: JAPYZE010000558.1:31204-55214[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00015 0.027 16.2 0.1 1 21 64 84 64 85 0.96

2 15 4.9e-05 0.0086 17.8 0.1 2 21 146 165 146 166 0.95

3 15 1 1.8e+02 4.2 0.9 1 11 273 283 273 286 0.90

4 15 0.0086 1.5 10.7 0.8 1 21 362 382 362 383 0.94

5 15 0.0012 0.21 13.4 0.9 1 21 468 488 468 489 0.95

6 15 0.16 28 6.7 0.2 1 13 536 548 536 551 0.81

7 15 0.00034 0.06 15.1 2.1 1 21 580 600 580 601 0.93

8 15 0.76 1.3e+02 4.6 3.0 1 13 609 621 609 623 0.92

9 15 3.2e-05 0.0057 18.3 1.4 1 21 676 696 676 697 0.96

10 15 4.3e-06 0.00077 21.1 2.3 1 21 794 814 794 815 0.96

11 15 0.012 2.1 10.3 0.4 1 21 912 932 912 933 0.95

12 15 3.8e-05 0.0067 18.1 0.2 1 21 994 1014 994 1015 0.96

13 15 0.0006 0.11 14.3 3.6 1 23 1023 1046 1023 1046 0.97

14 15 6.1e-06 0.0011 20.6 1.2 1 21 1130 1150 1130 1151 0.96

15 15 0.056 10 8.1 0.1 2 20 1209 1227 1209 1229 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00015	0.027	16.2	0.1	1	21	64	84	64	85	0.96
2	15	4.9e-05	0.0086	17.8	0.1	2	21	146	165	146	166	0.95
3	15	1	1.8e+02	4.2	0.9	1	11	273	283	273	286	0.90
4	15	0.0086	1.5	10.7	0.8	1	21	362	382	362	383	0.94
5	15	0.0012	0.21	13.4	0.9	1	21	468	488	468	489	0.95
6	15	0.16	28	6.7	0.2	1	13	536	548	536	551	0.81
7	15	0.00034	0.06	15.1	2.1	1	21	580	600	580	601	0.93
8	15	0.76	1.3e+02	4.6	3.0	1	13	609	621	609	623	0.92
9	15	3.2e-05	0.0057	18.3	1.4	1	21	676	696	676	697	0.96
10	15	4.3e-06	0.00077	21.1	2.3	1	21	794	814	794	815	0.96
11	15	0.012	2.1	10.3	0.4	1	21	912	932	912	933	0.95
12	15	3.8e-05	0.0067	18.1	0.2	1	21	994	1014	994	1015	0.96
13	15	0.0006	0.11	14.3	3.6	1	23	1023	1046	1023	1046	0.97
14	15	6.1e-06	0.0011	20.6	1.2	1	21	1130	1150	1130	1151	0.96
15	15	0.056	10	8.1	0.1	2	20	1209	1227	1209	1229	0.93

Sequence Information

Coding Sequence: ATGTATTCTTATAGTGAAAATCTTGTTCGACACGTTAAGTTTGAATGTAATATAGAGCCACAATTTGGTTGTGCTTATTGTTCAAAAAGTTCCAAACATTTTGAAAATGCATACGGTGACCCTTTATTTCTACCCGAGATGCCCATCCCCAGAATGATAATTCAAAGACATAAACAACAAAATAAGCCTTACGTTTGTCAAAAATGTGGTCAAGCGTATTCTTATCCAGGAAATCTCGGACGACACATTAAATATGAGTGTTTTTTAGAGCCACAATTCAGTTGTTTCTATTGTCCAAAAAGTTGTAAACGTATAAaTTTTAATGTTCTACTTAATGATCCCTTACTATTACAAAGTAAGCCTACAGTAAAAATGATCGAACATCAAATTATGGCAAAAATGGATAAACGTCGAATTACGAGTCAAGGCAATAACGTTTGTCCAAAATGTGGCAGATCATACACTTTGAAAGGAAATCTTGTTCGACATCTTAGATACGAGTGTGGTTTAAATCCACAACTAAGTTGTGCTTATTGTCCGCTGATCTGCAAACAAATAAATTTTAATGATCCAGTTATTGATCCCTTATCTTCACCAAAGAAGCCTACAACCAAAATGATTAAACCTCGCATGGAACGGTCTAATGATACTGTAGTTTTACTGTATAAGTCATCAACTCCAATGGGAAGATTTCGAATTAAAGATCAGGAAGATAAGCCTTACTTTTGTCCAAAGTGTGGCGGGTCACATGATTGGAATGGTGATCTTAACCAAAATTTACAATCTATAATGTTCGAACCTGGTTTTAATGGAAAATTTAGTTGTTCTTATTGTCCGAAGATGTACAAGAAAATAgATTTTAATGATCCACTTAATGATCCCTTATCATCACCAAAGGAACCTATAGTTAGATTGACTAGACATCGAATTAAGCATTCCAATACTTTGTTATCTTCACCAAACAGGCTCAAAGTCAAAATGCTTGAACCTCGAATTAAGCGTACCAATAAtacttcattttcaaaaaataagtcATCAACCGAAATAGTAAAACGTCAAGTTAAACATCAGAAAAATAAGCGTCACGTATGTCAAAACTGCGGCAGATCGTATACTTGGAAACGTGATCTTGTCCGACATCTTAAATACGAGTGTGGTGTCAACCCCAAATTCAattttaatgATCCACTTGATGATCCTTTATCATCACCAAAGAAGTCTAAAGTCACGATAGTTAGACATCGAATTAAGCGTTTCAGTACTTTGTTATCTTCACCAAACAAGGTTAAAGTCAAAATGCTTGAACCTCGAATTAAGCGTACCAATAAtacttcattttcaaaaaataagtcATCAACCGAAATAGTAAAACGACGTATTAAACATCAGAATAATAAGCGTTTCGTTTGTCATAAGTGTGGCAGATCGTATACTTGGAAACGTGATCTCGCCCGACATCTTAATTACGAGTGTGGTGTAAATCCAAAATTTGCTTGCGATTACTGTCCACAACTTTATCACAAAGATCCATCTGTTGACCCTTTATTTTTACCCAAGAGAATTACCATCAAAATGAATAATCAAAACGATATACGACAAAAATGTTACATTTGTCAAAAATGTGGCAAAGCTTATAATTCACATGatCTCGAATATTCATATTACAATCCTGTACTCGAACCAGAAAAGTCTTTCGATAGTGTCACCTATAAAGGAAATGTGCAACGAGATGGTCGTCACATTTGTCATAAATGTGGTAGAAAGTATCGCCAACGAGGGACACTTGCTCGACATGTTAAATATGAATGTGGCGTAAGGCCAAAATTTAGCTGTGGCTATTGTCAAAGAAGATTCAAACGTAAAAattTTGATGATCCACTCGATGATCCATTATCTTTACCAAAAGAGCATAAAGGCAAATTGGCTAAACATCAAATAAGGCGTTCCAGTACTTTATTGTCTTCACCAAACAAGCTTAAAGTCAAAATGCTTGAAGATCGAATCGAACGCCAGAGTATTGAACGTTACGTTTGCCATAAGTGTGGCCGttcatatactttaaaaaataatctcgcCCGACATCTTAAGTACGAGTGTGGTGTTAATCCAAAATTCAGTTGCGCTTATTGTTCTCAACGTTGCAGATACTTAGaTTTAAATGATCCACTTAATGATCCTTTATCCTCACCAAAGAAACCTGTAGTCAGATTGATTAGACATCAAATTAAGAGTTCCAGTACTTTGTTATCTTCATCAAAGAAAGTTAAAGTCAAAATGCTTGAATCCCGAATTAAGCAGCCCCATAATACttcattttcacaaaaaaagtcATCAACCGAAATAGTAAATCATCGAGTTAAACGTCAAAAGACTAAGCCTTATGTTTGTCATAAATGCGGCAGATCATATAATCAAAATTACTCACTAAACCGACATCTTAGATACGAGTGTGGTTTAACTCCAAAATTTGCTTGCGCTTATTGTCCATATATTTGTAAACAATTTAattttaatgATCCACTTAATGATCTCTTATCATCACCAAAGAAACCTATAGTCAGATTGATTAGACATCAAATTAAGCGTTTCAGTACTTTGTTATCTTCACCAAACAAGCTTAAAGTCAAAATGCTTGAACCTCAAATTAAGCAGCCCCGTGATGCTTCATTTTCACATAATAAGTCATTAACCAAAATAGTAAAACGTCAAGTTAAACACCAAAAGAATAAGCCTTATATTTGTCAAAAATGCGGCAGATCATATGCTTGGAAACATGATCTTGGCCGACATCTTAGAAACGAATGTGGTGTTAACCCCAAATTCAATTTATATGAACCACTTTATGATTCTTCAGCTTTACCAAAAAAACCTACAGTTACAAGAGATATTAATGATCCACTCAATCAACCTTCATCTTTATCAAAGAAGATTTTAGACAAAACTATCAGACGTCAAAGtagatataaaaacaataaacctTACGTTTGTCAAAAATGTGGTAAATCATACGCTTATAAAGCAGGACTTGTCCGACATCTTAGATACGAGTGTGGTGTACATCCAAAATTTAGCTGTGTTTATTGTCCAAAGCGTTGCAAACAATTAGATAGTTTAAAAGTGCATTACAAATCTCAACATCGTGAACAACCATTCATATACcaTTTTAATGATCCACTCAAGGATCCTTTATCTTCACCAAAGAAACCTGTAGTCAGATTGATTAGACATCAAATTAAGAGCTCCAGTACTTTGTTGTCTTCATCAAAGAAAGTTAAAGTCAAAATGCTTGAATCCCGAATTAAGCAGCTCCATAATacttcatttttacaaaaaaagtcatCAACCGAAATAGTAAATCGTCGAGTTAAACGTCATAGTAATAAGCCTTACGTTTGTCAGAAATGCGGCAGATCATATAATCAAAATTACTCACTAAACCGACATCTTAGATACGAGTGTGattTTGATGATCCACTCGTCGATCCTTTAGCTATACCAGAGATGCCCACAGTCTGTATAAATAAACGTCAAATTATACAACCcagtaatacaatatttttacaaaagaagTCATCAACCAAAACAGTAAAATCTCGAGTTAAACGTCAGAAGAATAAAGTTAACGTTTGCGAAAAGTGTGGCAGATCGTATGCTTGGAAGAGGGATCTCGTTCGACATCTTACATACGAATGTGGCGTGGATCCAAAATTTCGTTGTGCTTATTGTTCAAAGCgCACACTAAATCCTGCGATGGTTATAAGTCCTCAAGAAGTTCAACCgcaaaaacagcagcagcaactcaaCCAACAACAGCAggGTAATAATGCTGGTCAGCCTAAGACTCGGCCACTGATGACAGCAATAAATACAACAGTTATTTGGGAAGGTACACTTGAATGGGTTGATACGAAAAAAAGCACAAATGATGATCAAAATCAGATGTATCAATGTCCTTGTCAAATATCTGGATTCCATAAAAATGGCAAACCAAATGTaaacgCGGAATCTTGgccaaaaaaattgaaagtgcaATTATTGCCTAAAAGATTAGTAGGAAATGTTGGTAAAgcgtatttgaaaaattgtaaaccAATTCACATACAACCATCTAATTGTAATGCActtgaacttttaaaaaaaatattatctaatggATACacaGGACATGTTCATTTTACCCAAACAACTCACTGCAACATCAAAGTGCTTTTATTGTTGTATTCTGCTGAAAAAGATGCATTTCTTGGATTAATTCCTAATgaacaagaaaattttattaatcaattgaaaaagGTTATTTTACATTGGAAAAGTGTTTACGAAAGGATTCAACGAGCCCGCGTTACTTCAAAACCAGCCTCAACAAATATAGTTACAAATGTAAATGTAACATCTGAAGGTGTCCCCAATGTTTCCAATACTCCAAATAGCAGTCTTTCTGAGCTGCACCCGGTATCCGAGTTAGCAGAGCAAGAAAATCAAATGACCATACAAGCAGTTAAAATTACGGAAGGTATTCCAAAATTACAGTCGCAAATAAATACTAATGACAAAGCTTTGATAAATAAGCGTCAACAATTGAAACTTGCTCGAGAacaaaatttgctaaaaatacAAGAGTTGCAACGATCTTTAGAAGCTGCCCAGCAACAAGAGGCACAATATAAGTCACAAGAAGCACAGTACGAATCACAGATGGAAGTTGATGACGACGTAAATTGA
Protein Sequence: MYSYSENLVRHVKFECNIEPQFGCAYCSKSSKHFENAYGDPLFLPEMPIPRMIIQRHKQQNKPYVCQKCGQAYSYPGNLGRHIKYECFLEPQFSCFYCPKSCKRINFNVLLNDPLLLQSKPTVKMIEHQIMAKMDKRRITSQGNNVCPKCGRSYTLKGNLVRHLRYECGLNPQLSCAYCPLICKQINFNDPVIDPLSSPKKPTTKMIKPRMERSNDTVVLLYKSSTPMGRFRIKDQEDKPYFCPKCGGSHDWNGDLNQNLQSIMFEPGFNGKFSCSYCPKMYKKIDFNDPLNDPLSSPKEPIVRLTRHRIKHSNTLLSSPNRLKVKMLEPRIKRTNNTSFSKNKSSTEIVKRQVKHQKNKRHVCQNCGRSYTWKRDLVRHLKYECGVNPKFNFNDPLDDPLSSPKKSKVTIVRHRIKRFSTLLSSPNKVKVKMLEPRIKRTNNTSFSKNKSSTEIVKRRIKHQNNKRFVCHKCGRSYTWKRDLARHLNYECGVNPKFACDYCPQLYHKDPSVDPLFLPKRITIKMNNQNDIRQKCYICQKCGKAYNSHDLEYSYYNPVLEPEKSFDSVTYKGNVQRDGRHICHKCGRKYRQRGTLARHVKYECGVRPKFSCGYCQRRFKRKNFDDPLDDPLSLPKEHKGKLAKHQIRRSSTLLSSPNKLKVKMLEDRIERQSIERYVCHKCGRSYTLKNNLARHLKYECGVNPKFSCAYCSQRCRYLDLNDPLNDPLSSPKKPVVRLIRHQIKSSSTLLSSSKKVKVKMLESRIKQPHNTSFSQKKSSTEIVNHRVKRQKTKPYVCHKCGRSYNQNYSLNRHLRYECGLTPKFACAYCPYICKQFNFNDPLNDLLSSPKKPIVRLIRHQIKRFSTLLSSPNKLKVKMLEPQIKQPRDASFSHNKSLTKIVKRQVKHQKNKPYICQKCGRSYAWKHDLGRHLRNECGVNPKFNLYEPLYDSSALPKKPTVTRDINDPLNQPSSLSKKILDKTIRRQSRYKNNKPYVCQKCGKSYAYKAGLVRHLRYECGVHPKFSCVYCPKRCKQLDSLKVHYKSQHREQPFIYHFNDPLKDPLSSPKKPVVRLIRHQIKSSSTLLSSSKKVKVKMLESRIKQLHNTSFLQKKSSTEIVNRRVKRHSNKPYVCQKCGRSYNQNYSLNRHLRYECDFDDPLVDPLAIPEMPTVCINKRQIIQPSNTIFLQKKSSTKTVKSRVKRQKNKVNVCEKCGRSYAWKRDLVRHLTYECGVDPKFRCAYCSKRTLNPAMVISPQEVQPQKQQQQLNQQQQGNNAGQPKTRPLMTAINTTVIWEGTLEWVDTKKSTNDDQNQMYQCPCQISGFHKNGKPNVNAESWPKKLKVQLLPKRLVGNVGKAYLKNCKPIHIQPSNCNALELLKKILSNGYTGHVHFTQTTHCNIKVLLLLYSAEKDAFLGLIPNEQENFINQLKKVILHWKSVYERIQRARVTSKPASTNIVTNVNVTSEGVPNVSNTPNSSLSELHPVSELAEQENQMTIQAVKITEGIPKLQSQINTNDKALINKRQQLKLAREQNLLKIQELQRSLEAAQQQEAQYKSQEAQYESQMEVDDDVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -