Lsin034149.1
Basic Information
- Insect
- Leptidea sinapis
- Gene Symbol
- L
- Assembly
- GCA_905404315.1
- Location
- FR990195.1:6704109-6715952[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 0.49 67 5.4 5.8 1 23 3 25 3 25 0.97 2 16 4.4e-06 0.0006 21.3 5.1 1 23 31 53 31 53 0.99 3 16 2.1e-05 0.0028 19.2 0.1 1 23 59 81 59 81 0.98 4 16 4.6e-05 0.0062 18.1 0.5 2 23 97 119 96 119 0.93 5 16 4.9 6.6e+02 2.2 0.2 9 23 151 166 147 166 0.93 6 16 0.52 70 5.3 0.1 3 23 220 240 219 240 0.97 7 16 4.7 6.3e+02 2.3 0.1 3 23 255 275 253 275 0.81 8 16 0.00062 0.084 14.5 5.7 1 23 283 305 283 306 0.93 9 16 0.0063 0.85 11.3 0.1 1 23 311 334 311 334 0.94 10 16 0.0041 0.55 11.9 0.2 1 23 394 418 394 419 0.95 11 16 0.00014 0.018 16.6 0.1 2 23 471 492 470 492 0.96 12 16 0.4 54 5.6 0.0 1 23 500 522 500 522 0.95 13 16 3.5 4.7e+02 2.7 0.7 2 23 530 551 529 552 0.91 14 16 0.41 55 5.6 0.4 3 23 628 648 627 648 0.95 15 16 0.0043 0.59 11.8 0.1 1 20 656 675 656 678 0.95 16 16 0.034 4.6 9.0 0.2 1 23 685 707 685 707 0.96
Sequence Information
- Coding Sequence
- ATGCCATTTCGTTGCGAGTTTTGTTCGAGACTGTTCAAGCACAAGAGGTCACGTGACCGGCACGTGAAGCTGCACACTGGCGACAGGAAGTACCGGTGTTCCCATTGTGAATCAGCTTTCTCGAGGagCGACCACTTAAAGATTCACATGAAAACCCACGACAACCAGAAGCCGTTCCAGTGTACCGTCTGCAACCGAGGATATAACACGGCAGCCGCGCTCACTTCTCACATGCAGGGACACAAGAGGGACCGGACCGCGAGAGACATGGACAAGAGAAGGGGACTCAAGTGTGGTCGATGCGGAGAGAACTTCCGCCGACATGACTTACTGCAGGCACACATGTCTGCTGTGCACGGCATTGAGACACTAAATCCGTTGACACCACCGAGACGCGTGGCTTCACAGCCGCTGCCCACGTTACTTGCATGCATCTACTGCACACGAGACACATTCACGAGCATGGAACAGTTGCAACTGCACGTGAGAGCATCGCATTCAGCACTCTTAAGCGGTGAAGCCACTTTCAAAACAGAACAGCCAGCACCCACGGACTTGAGCCGACGAAGCTTAGAAGGCACTCCACCAGTCAAAAGACCAAGATCAAGTTCCGGCTCAATGACACCTCAAACATTGCTATCTCCGAGTACATTACTGTGCAACCAATGCAATGCAGCGTTGCCAGATTTTGAGGCTTTCCGTGTCCACCTAAAAGGTCACCTTGAAGAAACAGGGGATTCGGGAAATACAAGTCCAACGCCTTGCATACACTGTGGAGCAAAGTTTTCTGATCCTTTGGAGTCGGAGCGGCACGTGGCGGCCCATTATCTGGCGGTTTCATGTGAACACACGTGTCATACTTGCTCCCGAAGCTTTCCAACTCAAGATGAACTCGTGAAACACTTGTTTGATCATCACGTTCACACGTTATATAGATGCACTCTTTGCAAAGAAGTATTTGAATCGAAAGTGGCGATACAGGTACATTTCGCGATGGCCCACAGCAGTGAGAACAAGATATGGGTGTGTCGGTCGTGCGGCTCGAGCGGCGGCGCCCTGCGGTCGGAGGCGGAAGGTGCGGCACACGTCCGCAGCCGCCACGCCGCCGCGCGCTGCGGCTGCGGCGCGGTGGTCGCCGGCGCGCGGGCCTTGCGGGCACACTGCGCTCGGCACCACAGCTACCGGTGCCCGGTTCCTTCCTGCAGCGACGCATTCGCCGTCCAGTACTTACTAGAGAGACACATGCAAGTTCACCACACTATGCCTCCACAGGAGTTTAACGGCGATGTAACGAGAAACAAAAGAATAAACAACAACAACGGAGAAGAAACTCCTTGTGATTTGCCCGGTGATAATGGTCCTATACCTCCTCCAGAAGATCGTCGTCGGAAGAACGGCGCAGTTGCTTTACAGTGCGCATATTGTGGCGAACGTACGAGGAGTAGGGCGGACCTGGAAGCGCACACCAGGGCTCACTCCGGCAACACTGTGGCGCGACATAAGTGTCTCATTTGTGACGAAGTGCTGCCCTCTGCCGCGATCTTAGCTGAACATAAACTTACTCATTGCAAggtGGTTGCGGGGGACACCTGTGCTCGCTGTCGCTCAAGGCTGCCTTCAGAAGATGCGTTCCTAACTCACATGGCTCGTCACCATCCAACATTACCAGCACCTTGCATAATTTGCCGGCAAACTTTAGCTTCTGAAGCCGAAGCGCGCCTTCACGCTCGGTTCCATTTACGACCCAGCGAAGACGAACAAAGATGTGCTATTTGCTTAACAACGCTCACTGAGAGTGAGTGTGGAGGTGGGGTGCGTGCTTGCTCGTCGTGTTACGCTCGACATTCAACTCCTCGGCCCCCTCCACCGACAGACAGTGACTGTCGCCTCTGTAGAAGATCACTCGAGTCTCCCACACGACTCCAAACTCACCTTATCGAACACACTTTCGCTGGAATAGGTTCCTTCAGCTGTTACTTATGCTCAGCTGTATTCACAAGCGCAGCGGGGCTACAAAGACACTTACCGGAACACCCCACTGCTTCTAGGCCATACGATTGTGGTCGATGTGGTTTGAAATTCTTTTTCCGAGCGGAATTGGATAACCACGCGTTGATTCACTTAGAAGAAGCAGAATTGGCCCAGAGGGCGTTTTATGAAGCGTATGCTAGAGGTGCTGTGACCGCTTGGGCAGCTATGCAATCTGAAACTTCCCCTAAGCCGCTGCCACCGGGCCCTTCGACAACGACAGAGTTGAAAGTAAAGCAAGAGAATGAAATTAAGGAGGAGAAAAATGATGAATACATTGAAGTATCATCGCCACCTCCACCGCCAGTAGACCCTGAGCCCTCAGATCCAACAAAGGTTGTGGTAAAACAAGAAAAACCTGAAGAGGATAACTAA
- Protein Sequence
- MPFRCEFCSRLFKHKRSRDRHVKLHTGDRKYRCSHCESAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQGHKRDRTARDMDKRRGLKCGRCGENFRRHDLLQAHMSAVHGIETLNPLTPPRRVASQPLPTLLACIYCTRDTFTSMEQLQLHVRASHSALLSGEATFKTEQPAPTDLSRRSLEGTPPVKRPRSSSGSMTPQTLLSPSTLLCNQCNAALPDFEAFRVHLKGHLEETGDSGNTSPTPCIHCGAKFSDPLESERHVAAHYLAVSCEHTCHTCSRSFPTQDELVKHLFDHHVHTLYRCTLCKEVFESKVAIQVHFAMAHSSENKIWVCRSCGSSGGALRSEAEGAAHVRSRHAAARCGCGAVVAGARALRAHCARHHSYRCPVPSCSDAFAVQYLLERHMQVHHTMPPQEFNGDVTRNKRINNNNGEETPCDLPGDNGPIPPPEDRRRKNGAVALQCAYCGERTRSRADLEAHTRAHSGNTVARHKCLICDEVLPSAAILAEHKLTHCKVVAGDTCARCRSRLPSEDAFLTHMARHHPTLPAPCIICRQTLASEAEARLHARFHLRPSEDEQRCAICLTTLTESECGGGVRACSSCYARHSTPRPPPPTDSDCRLCRRSLESPTRLQTHLIEHTFAGIGSFSCYLCSAVFTSAAGLQRHLPEHPTASRPYDCGRCGLKFFFRAELDNHALIHLEEAELAQRAFYEAYARGAVTAWAAMQSETSPKPLPPGPSTTTELKVKQENEIKEEKNDEYIEVSSPPPPPVDPEPSDPTKVVVKQEKPEEDN*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00430847;
- 90% Identity
- -
- 80% Identity
- -