Basic Information

Insect: Leptidea sinapis
Gene Symbol: Bcl11b
Assembly: GCA_905404315.1
Location: FR990190.1:5111358-5136470[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.012 1.6 10.5 3.8 2 23 70 91 69 91 0.96

2 13 0.045 6.1 8.6 3.1 3 23 99 120 97 120 0.88

3 13 0.15 20 7.0 0.2 2 23 128 150 127 150 0.93

4 13 1.7e-05 0.0023 19.4 3.6 1 23 156 178 156 178 0.96

5 13 1.2e-05 0.0016 19.9 2.0 1 23 184 206 184 206 0.98

6 13 0.00067 0.091 14.4 0.3 1 22 212 233 212 233 0.95

7 13 0.0088 1.2 10.9 1.1 3 19 253 269 252 274 0.92

8 13 3.1e-06 0.00042 21.7 2.6 1 23 545 567 545 567 0.98

9 13 0.00011 0.014 16.9 0.1 3 23 576 597 576 597 0.92

10 13 0.0016 0.22 13.2 2.0 2 23 606 630 605 630 0.92

11 13 5.2e-05 0.0071 17.9 0.3 2 23 637 660 636 660 0.94

12 13 0.00068 0.091 14.4 1.4 1 21 666 686 666 687 0.96

13 13 0.00052 0.071 14.7 1.4 1 20 700 719 700 721 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.012	1.6	10.5	3.8	2	23	70	91	69	91	0.96
2	13	0.045	6.1	8.6	3.1	3	23	99	120	97	120	0.88
3	13	0.15	20	7.0	0.2	2	23	128	150	127	150	0.93
4	13	1.7e-05	0.0023	19.4	3.6	1	23	156	178	156	178	0.96
5	13	1.2e-05	0.0016	19.9	2.0	1	23	184	206	184	206	0.98
6	13	0.00067	0.091	14.4	0.3	1	22	212	233	212	233	0.95
7	13	0.0088	1.2	10.9	1.1	3	19	253	269	252	274	0.92
8	13	3.1e-06	0.00042	21.7	2.6	1	23	545	567	545	567	0.98
9	13	0.00011	0.014	16.9	0.1	3	23	576	597	576	597	0.92
10	13	0.0016	0.22	13.2	2.0	2	23	606	630	605	630	0.92
11	13	5.2e-05	0.0071	17.9	0.3	2	23	637	660	636	660	0.94
12	13	0.00068	0.091	14.4	1.4	1	21	666	686	666	687	0.96
13	13	0.00052	0.071	14.7	1.4	1	20	700	719	700	721	0.95

Sequence Information

Coding Sequence: ATGGAATCTAACATATCGTTCTATAGTTTACCTtttttagacTGCGAACATGTTGAATTAGACCTAAAAAGGGAAACTGATTGTCAGTTTGATATTCATAATACTCTATCAGCAAGCAGTGCATTACTTGGAGGAGATGATGTTCTAGCCCAATTTCTAACTGATGGCCCCTTGGAGGAACCTGATCTAAATGGGCCAGCATCATTGCATTGTGAGATTTGTAAGAAGCAGTTTGACAATGCTAAGAAGTATCATGGACATTTAAGGGTTCATTCAAAAGATAATCTATGGATTTGTGATAAGTGTACTGATCAAAAGTTTACTACAAAGCAACACTTAATGAAACATAGTTTGACTCATAAGCCGCTAGCTAGAGTCTGGAAGTGTCCACAGTGTAGCATGGCGTTTGAAGCACTTTGGCGATTGCAACAGCACTTGTTCTCTAAACATCTTCATTacaaGCCTCACAAGTGTGACAAGTGTGAGAAATCATTCACCAAGTTGTCAGATTTGCAAAAACATAAAGATGTCCATGAAGgTGTGGGTAAATTCGAATGTACCACATGTAAGAGAAAGTTCAAAGATGGCTCCAACTTGAATAGACACGAGCTAACACATACCAAAGATAAATCATTCATTTGTGTTGGTTGTCAAAATAGATTTGCACAGTCAGGTTCACTGCAACGACATCAAAAGAAATGCAGAGCTTATCTAAATCTAAACATAATTGAAGACAAGTCTATAAGGAAGAACTATTGCCGCGTTTGTGGTATGGTGTTCAAGTATAAAAGTGCTTTGCTGGAACACTGTGTCAGgcaacattcaaattcaaataatagtgACAATGAGcaaaacacaataaatgttGACACAAACAGAATGGTAGACAATATAGTTGATGACATACTCTCAGCTGAGGATGACTACATGACAATGTCCACATCTCAAGATCTCATGAGTTTCTCAAGTGTACAGACTCAGAACTATACTGCGCCTGGCTACGAGAGTTTAATGCAAGTTGAATTACTCAAAGAGATGAATCAACTGCACTCTCTAGATGATGAGCTTCTATATAATGATTTGTACTTTGATGGTCTACAAAGTAATCAGACATTCAATATGAATACAAATGATATTGATTATAGTACAGATAATACAGAGTTATTCGAATATGtgaatgaaaacaaaaatattgatcAGGATTTTCTAAACACTCTGAGCTACACAAAAGATAGTATGCAGGATGAATTGCTAAATTTAAATAGCACTGATAGAAACCAACCATTGACATTAACTGAAGATTGTGCTACTATATTTGAAAGTGATGTCGATTTAGAAGTAAGTACGAATCTTGCAGCAAACTTAAACCAACTGATTGGTGAAAACAGTGTGCAATATATATCTACTGAAGATGAtgacacatttataataagccTGAATAGTGAAATTGATGCCGCTAGACTAACAGATATGTTGAACAAGGTTGAAGTAGTGAATAAGATTGATGAGTCAGAGTATATGCCTGAAGTAAGCGACAAGAGTCATCTTCTTGAATATATAGTGCCATTTATTAAGCCGACAGATAAGTGTGAGAAAACCGAAGTTGAGAAAAAAGTTAAGACGAAACCGCTTTACTTCTGCAACACTTGTGGTAAAATATTCAAGAAAAAGGATAATTTTAAATCTCATTTAgCCACGCACGACGCGTCACTCCGGCGGCACGGCTGCCCGGTGTGCGGGCGCCGCTTCGGGTACCGCTCGTCACTCAACAAGCACGTGGCGGCCGCCCACGAGCCTCGCACGCGGCCCGACCACGCCTGCTCCGTGCAGCGCTGCGACAAGCACTACCCCACCGCCTGGCAGTTAAAGAATCATATCAAGAGAGACCACGAGATGGCGCTTAAGTGGGTGTGCGAGCGGGACGGCTGCGGGAAGAAGTTTTACAAGAAGAGCGATCTAGTCGTGCACACCAGGTACCACACGGGCGAGCGGCCGTACCAGTGCGAGTCGTGCCAGGTAACGTTCGGGCAAGTGTCGCACCTCAGACGGCACCGCAAACGCCTCCGGTGCGCCAAGTACCACAGGGGCGATCGGCCGTACCAGTGCGAGTCGTGCCGGCAAACGTTCCGGCGAGTGTCCCATCTCAGAGAGCACCGCGAACAGCTCCGTTGCGCCAAATCGGGTGGTTGTCGAAAAAATGATTCACTGTTGCAGAAGCCGAAGAAAGAAATTGTGACGACTTGA
Protein Sequence: MESNISFYSLPFLDCEHVELDLKRETDCQFDIHNTLSASSALLGGDDVLAQFLTDGPLEEPDLNGPASLHCEICKKQFDNAKKYHGHLRVHSKDNLWICDKCTDQKFTTKQHLMKHSLTHKPLARVWKCPQCSMAFEALWRLQQHLFSKHLHYKPHKCDKCEKSFTKLSDLQKHKDVHEGVGKFECTTCKRKFKDGSNLNRHELTHTKDKSFICVGCQNRFAQSGSLQRHQKKCRAYLNLNIIEDKSIRKNYCRVCGMVFKYKSALLEHCVRQHSNSNNSDNEQNTINVDTNRMVDNIVDDILSAEDDYMTMSTSQDLMSFSSVQTQNYTAPGYESLMQVELLKEMNQLHSLDDELLYNDLYFDGLQSNQTFNMNTNDIDYSTDNTELFEYVNENKNIDQDFLNTLSYTKDSMQDELLNLNSTDRNQPLTLTEDCATIFESDVDLEVSTNLAANLNQLIGENSVQYISTEDDDTFIISLNSEIDAARLTDMLNKVEVVNKIDESEYMPEVSDKSHLLEYIVPFIKPTDKCEKTEVEKKVKTKPLYFCNTCGKIFKKKDNFKSHLATHDASLRRHGCPVCGRRFGYRSSLNKHVAAAHEPRTRPDHACSVQRCDKHYPTAWQLKNHIKRDHEMALKWVCERDGCGKKFYKKSDLVVHTRYHTGERPYQCESCQVTFGQVSHLRRHRKRLRCAKYHRGDRPYQCESCRQTFRRVSHLREHREQLRCAKSGGCRKNDSLLQKPKKEIVTT*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00874726; iTF_00875622;
90% Identity: iTF_00874726;
80% Identity: -