Basic Information

Gene Symbol
-
Assembly
GCA_905404315.1
Location
FR990163.1:2623927-2633638[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 0.021 2.8 9.7 1.4 3 23 646 667 645 667 0.92
2 23 0.04 5.5 8.8 0.6 1 22 1041 1062 1041 1062 0.95
3 23 6.1 8.3e+02 1.9 0.3 1 22 1104 1125 1104 1127 0.82
4 23 0.24 32 6.3 0.6 3 21 1138 1156 1136 1157 0.94
5 23 0.61 82 5.1 0.0 3 23 1166 1187 1164 1187 0.89
6 23 0.038 5.1 8.9 0.1 3 23 1207 1228 1205 1228 0.96
7 23 0.0063 0.85 11.3 2.5 1 23 1234 1257 1234 1257 0.95
8 23 0.11 15 7.4 0.0 1 23 1281 1304 1281 1304 0.90
9 23 0.035 4.8 9.0 3.3 1 23 1309 1331 1309 1331 0.96
10 23 0.0033 0.44 12.2 0.2 1 23 1337 1360 1337 1360 0.95
11 23 0.0073 0.98 11.1 1.6 1 23 1374 1396 1374 1396 0.97
12 23 0.00016 0.022 16.3 1.8 1 23 1448 1471 1448 1471 0.97
13 23 0.0037 0.5 12.1 1.8 1 23 1532 1555 1532 1555 0.96
14 23 0.0016 0.21 13.2 1.4 2 23 1577 1599 1576 1599 0.95
15 23 0.09 12 7.7 0.2 2 23 1605 1627 1604 1627 0.95
16 23 0.0089 1.2 10.9 0.2 1 21 1671 1691 1671 1692 0.95
17 23 0.0011 0.15 13.7 0.6 1 23 1702 1724 1702 1724 0.93
18 23 0.00019 0.026 16.1 0.3 2 23 1820 1842 1820 1842 0.93
19 23 1.6e-07 2.2e-05 25.8 1.1 3 23 1849 1869 1848 1869 0.98
20 23 0.00046 0.062 14.9 0.2 1 23 1887 1910 1887 1910 0.95
21 23 0.17 23 6.8 0.0 1 23 1935 1957 1935 1957 0.97
22 23 0.003 0.41 12.3 0.3 1 23 1963 1986 1963 1986 0.96
23 23 0.00023 0.031 15.8 0.4 1 23 1994 2017 1994 2017 0.96

Sequence Information

Coding Sequence
atgagTGTGAATTATGATAGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTATTACCAATTTTCCCTACCACCAGTTCAGATGACACCGAATCTCCTGCCCTTGCATCTAAAATCAAGGATTGCGTGTCTGTTCAGATACACGAAAATGATGAATTACCAACTAATGTCTGCAGGAAATGCGTGGAAAACGTCAATAATTGGCATATTTTCAAGTCAGTTTGTGAAAGGACACAAAACAAATTACAGTCACTCATTAACAAGGGGAGCAGCCTACTAGAAGAGATTAGAGTTAAGAGTGAACCAAATGAAGGTTTATCAGATGAAGCATATGATGATGGAGTTGTCATCGATGGCTCATATCCAGACAATGAGACTCCAACAACTGCTGATAAGGTTCAACCAGAAGGACCACCGATCTTGGCATCACTCGGTCTAACACCTCGCAGTGATAAGAAATATATAGATCCAAGAATGGATTGGATGAGAGTCCATGCAATACTGAATATAATTCGAGATGATGATATTATTGACTCACTCCAACGTAATGAAGAGTGTGAGGTTATTCATCAGTCCGATCATGATTCTGAGTGTGATTCAGAATTAAGAAGTGATACACCAGATAACTGTATTGATAGCATGGGCTATAAATGCTTAAATAATAAGGTTTTAACTAAGAATCCTCAATTGTCAAAAGCTGAGatacagaaaaatataaaagaatgtTTGAAATTAAGGCAGAGCAAAATTGAGACTAGGAAAATATATTCACAGCCAATAAATGTTTGGAAATTGTTATTTACTGATGACTTGATTGAACTTATTGTATCATCAACCAATGCCGGAATTGGTAACACCAATCATATGACTTatgttaatgaaataaaaacattagttGGTATACTGTACTATGTTGGCATAATGAGGCCAACACATCAGAAATGCAGTGACCTCTGGGACATTAAATGTGGCACACTTTGCATCAGAGAAGCAATGAAATATGAGAGATTTAAATTTCTTCTACAGAATCTGAGGTTTGACAATAAAATTGATGATAGCATTATGGAAATAGATATCATGAAGAGAATGAGAAAAGTTTTTGAGATATTTGCATACAATTGTAGAACATCCTTTAGTATTGGTAATACTGCTGTCATTGATGAAGTTCTGCTTCCGATTCAAGGCCCATGCCCATTTAAATATAGCATTGAAAAGAAAGAAATCAAGCAAGGAATTAAAATGGTACTTCTGGTGGATCCggagaatttttatatttctaatcTGGATGTCATTACAGATCCATATTTTGGTGCAGAGGATATAGCAATGAAATTACTTCAGCATTTTGCAGATTCCGGAAAAACAATTGTTATGGACAGTTGGTTCTCATCACTGACATTAATCAATAGGCTTAAGAaggaatataatttatacagcaTGGCCGCACTACACCCAACTAATGACAACATTCCACCTTTATTTCTTTCACACCACAGGTTATGTAAGCCAAGTTTGGGGGGCTTTTTGAACAATGAGATGGTTTTATCATCACTTGTGAATTCTGAACATAAGGTCGCTCATGTACTGACAAATGATCCCACATATTACAAGAAGCGTGCCTGTTCAGTTTCAACGTATAAAAGACATGTTTCTGCTGTTCAAGTCGTAGATGTTCTAATGCACTATTATACAACAATGCAAAATACAAATGATTGGACTCTCTCTTTATTCTTCATGCTTTTGAATATTGCCTCTATAAATGCTCAGGGAACGGAGAGCGACAAAGATGAAGAAGAGGAAGAAgcagaaataaataaagaatccAAAAATCCTGTGACACCCAAAATCCCTGAAGTATCAATTACAGTAATGCGAAATACAGGTGAAACATTAAACGCCCGTCAAGGTATTCAGCAACTTGCTTCCAAAGATTGTCTAGTGTGTGGTCGATCTTATAGATATTCCCATAATGCACGTCGACACGAACTTAATTCTCACAGCTTTGAtagatatacaaacaaaatCACGGCAAAAAAGCAATACAATCATAATATGCAACCAAAACTTAGACCAAATCCATTTAATCCGAAGGCTCGTTTAATGCCAAATCCAATAAACCATAAAATGCAGCGCTTACATAGTTCTGTTGCTCCTTTCAAAATGGCTCCTCAAAAGTTACAAGTCCCACCTAGACCAATCCCTATAAGGAAAGCACAACAAAATAGTCTACCATATCCTCTACGCATTAAAGCTCTGAAAGATTTACAAATCAAGAAAAAGGAAccacaaattttaaaaactttgctTACTTCTAAGCCAGAGGTGCTTGTCTCAGAGCCAGAAATACTCAATTCGGGGCCTGAAAGTCCCGAGACATTGATTTCTGAACCAGAAATAGCGTCATTCCAGGTAGAAACTATTTTGTCGGAACCTGAAGTCTTCGTGGATCAAAATCAAGACGAAGTCGAAGCAGAAGTAGAAAATGAAGATGATGTACCAAACAACCAAGGTAGAAATTATGACACTGTAGATATGGACTCGgaaaatgaaatagaaataGCCAGACAGGGAGAGTTCGAAGATCAACCGAGTGAAACAGTTGAAGATGAAATTGaagagaatattaaagaagaaGTAAGTACTGCCGATGTTGAAGAAGAGCAAAACGATGATGAAAGAGATGAAACGGACTTTATTGGTGATGAACACAATGAAGAAGACAATGGTGAGATTGCCGAGAAGGAAATCAACGATAAAGAAGAAAAGGCTACTGAGAATCATGGGAATGACTATGATGATGAACTAGTTCCTATGGCGCCTGTCGTCGAGATAAATGAAGAAATACAGAATAATTCTTAccataatgaaaataatgaagaGGAAGAAGGAGATCTTGATGAATCTGGTGATCCTAATAATACGGTGGAGGATGAAGAACCCAAAGAGCTTGACCCAGACAAACAGTATGTCACTAAAACACAAcgtgaatttattaaaaaatatcgaGATATCATTGAACAGATCAATACCAAAAGATGTCTATGTTGTGATAGAGAACATCCTCGAAGAAAAGCTGTTATACAACACTTGCAGAAGAATGGCCACAAGGTTCCAAAACATACCTGTTACAATTGTGTTGTCACTTTTAGTCACATTGGAGCTTTGCTTAGCCACATGCGATCAAATACCTGTACTGACTTGTGGAAGATTATTTACAACGAAAATGGTATAACCGATGATCAGGTTCTTGAAGATGAACCAAAAGATGCTAAAGTTCaatacaaagatatatttaatgcaaggTCATATGCATGCAAATTATGTCCTGCAAAATTccaattgaaacaatttattatgaaacATGTTTTAGATGTCCATGAGGACGGACAATCTCGAGTACATCTAGCTTGTGTCCATTGTCGTGCTCGATTTAAGGATAAGAGTATTTGGAAGAGACACATTCGGAATGGGGAATGTACTGTTTATATTGCTTGTGATGTGTGTCCAGAGAAATTTGGCAACATGCAAGATTTTAATGAACATGCTTTGGCTATTCATGCTGGAAGCTATGACCCTGATAATCAGAACAAGTGTGTTGACGGCCGCAGAACTGATTGTCCCATATGTGGAAAGAAAAACAGTGGCTATCCAAATTTAGTTAAACATTTGAAAATAGTTCACAATGAAGAAAAACCACATTACTGCAAACATTGTGATGCCAAATATGAATATGCTACTGAGCTAAATAAACACATATACATAGAGCACTCTGATAAGGTACTTGGAAAACAAGAACCAGATATGTCACTTGTAAAAGAGGAAACAGAGGAATATCATTACTCTTGTACAGAGTGCAATGCCATATTTGAGACTGTCGATGCTTGGACTGATCATCAGGTGGCGGAACATAATCAAATTGCTCACCATTGCGACCAATGTGAGAAGAAGTTTTTAAGACCTTCGGAACTTGCCGAACATAAGAACAGCCATTTGCGTGTCAAATTCTATCCCTGCAGTATTTGTAATAATTCTTACAGTACTCCACAAAAACTATCTGAACATGTGCAACAAGCTCACCCTGGTGCTACTATCGTGGGACCCAATGGTGAGAGTGAATTCTTTTGTGATCTTTGTATTAGATCATTCAAGAGCCGACAGGCCTACTCTAATCATATGCGTATTCATTCCAAAGTTCCAACCACCAACAGAAAACCGGGAGAACCAAAAGGTTTCTCCCCACAAATAATTGGGAAACCAATTCGTCATTTCTCGATAGTACAGCAACCAGGGATCAGTCAGGCTCCCTATAAGCCGAATATTAATGTGCCAAATGCCCCATATTCTTGTGACATTTGTGGAAAAGGATTCATGCACAAGAAAAACATATGgaaacacaaaaaagtattgCATGCTGATATGGTGAACGATCGTAATGACAGTGAAGAGAATACAATGCATGCCTCAACAGAAGAAGATGAATACAACCCCGACGAGAATGGAGCTATGTTGTCTACGCCACAATTCAACAGCTTCAACTTCGCCAATTTGCCAAATTCTATGCAATCAACACCCAGTAAGGATGCAATGCCATTCTCATGTGATTTGTGTTATAAACGATTCCCACTTAAAACTAGTCTTTGGAAACACAAACGCGCTAAACATGGAATAATAAACGCCAGTTCCACAGACCCTGCATCAGTGGAAGCGAGCGGCAGTAGTAGGTCGAGTTGCACTATTTGCAAAATTAGTTTTGCGGACAAGAAATCATATTATCGCCACAGAAAGAACGTTCACAAATCTACAGTGCAGATGTGTAAACTTTGTGGCAAGCCACTTAACTCGACATTGGAACTATATGAACATTTGAAATCGGCGCACGCTCGAGAATTATTGGGATACAATGAGAGTCAAGGTCCCAGCAAGGCGCAAGAAGTGATACCTGATGTAGATATGGATTATGAACCTGAACAAGAATCACTAGACCCCAGTGCCGATTACCAAGCGTGCTACCCCTGCGATACGTGTGGGAAACAATTTGTCGGCTTACTCGCGTTACAAAATCATCAATGCGTTAACCAGATGAACCCTCAATCCCAGACATTTGATTGTGAAATATGCCACAAGAGTTACACATCTATTGCTGCCTTGAAAAGTCACAGAGGTTGGCATCTCCGTTCACCGGACGGAAAGGCTGCCGCTAACAACAGCGGCTTGTGGATGCCCCAAAATAAAGTAACCAACAAAGTGAGCAAATATGAAGTGTTAGATGCGTCCCAGCTAGCTCGAGTTCAACATTCCATAGCACCGACACCGTCGTCATCGTCTGCAGCAGTCAAGCGAAGACTGCCTCCCGAAGTCGAGGTTACCGTGGTCAATCCGAACAAAAAATTACGATCCGACGACTCTGTAGATATTGACAATCAGACGAACATGTCCACCGGCATTGACGACAGATACTGCAACATATGCGATAGGGAGTTCACGAAACGGGCTGCATATCAGCGTCATATGGATGAGGTTCATCAACCGAATTCGGTATTTTGTCCCGTATGCGACAAGAGTTTCACAAGAAAATCGACATTAATTGTTCACATGAAGAAACATTACGATGGCGGTGAAGGTAGTTCTGTGATGACGCAGGTGGATGACGAAATATACGCTTGTGAAGTTTGCGGAGAGAGGTTCAATAACTCAGCCGAGTACAACATGCATCGAGAGTCGCAGCACGGTGAAGATGAGACGGCTGGAGAGTCTGAGGAGGATGATGGTGGTTCGATACCGATGCCGCAGCCTGGTGAGTTCACCTGCGCGCAGTGCGGAGACGGAGTGGCAACGCCGCGGGACCTGATAGCTCACCGAACGATGCACGCCACACCAACTAAGTTCTATTGCAACATTTGCAACGTCTACTTCGCGAGGGCAATAGATTTGTCTTCACACACTCGGGCGAGGCATGCTGACAACGAGAAAGTTTTCTTCCCGTGCGCCATGTGCGACCGATTTTATATGAACAAAAAGAGTTTACAACGACACATCGAAATGGCCCACTGA
Protein Sequence
MSVNYDSVCRLCLSSRGELLPIFPTTSSDDTESPALASKIKDCVSVQIHENDELPTNVCRKCVENVNNWHIFKSVCERTQNKLQSLINKGSSLLEEIRVKSEPNEGLSDEAYDDGVVIDGSYPDNETPTTADKVQPEGPPILASLGLTPRSDKKYIDPRMDWMRVHAILNIIRDDDIIDSLQRNEECEVIHQSDHDSECDSELRSDTPDNCIDSMGYKCLNNKVLTKNPQLSKAEIQKNIKECLKLRQSKIETRKIYSQPINVWKLLFTDDLIELIVSSTNAGIGNTNHMTYVNEIKTLVGILYYVGIMRPTHQKCSDLWDIKCGTLCIREAMKYERFKFLLQNLRFDNKIDDSIMEIDIMKRMRKVFEIFAYNCRTSFSIGNTAVIDEVLLPIQGPCPFKYSIEKKEIKQGIKMVLLVDPENFYISNLDVITDPYFGAEDIAMKLLQHFADSGKTIVMDSWFSSLTLINRLKKEYNLYSMAALHPTNDNIPPLFLSHHRLCKPSLGGFLNNEMVLSSLVNSEHKVAHVLTNDPTYYKKRACSVSTYKRHVSAVQVVDVLMHYYTTMQNTNDWTLSLFFMLLNIASINAQGTESDKDEEEEEAEINKESKNPVTPKIPEVSITVMRNTGETLNARQGIQQLASKDCLVCGRSYRYSHNARRHELNSHSFDRYTNKITAKKQYNHNMQPKLRPNPFNPKARLMPNPINHKMQRLHSSVAPFKMAPQKLQVPPRPIPIRKAQQNSLPYPLRIKALKDLQIKKKEPQILKTLLTSKPEVLVSEPEILNSGPESPETLISEPEIASFQVETILSEPEVFVDQNQDEVEAEVENEDDVPNNQGRNYDTVDMDSENEIEIARQGEFEDQPSETVEDEIEENIKEEVSTADVEEEQNDDERDETDFIGDEHNEEDNGEIAEKEINDKEEKATENHGNDYDDELVPMAPVVEINEEIQNNSYHNENNEEEEGDLDESGDPNNTVEDEEPKELDPDKQYVTKTQREFIKKYRDIIEQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVVTFSHIGALLSHMRSNTCTDLWKIIYNENGITDDQVLEDEPKDAKVQYKDIFNARSYACKLCPAKFQLKQFIMKHVLDVHEDGQSRVHLACVHCRARFKDKSIWKRHIRNGECTVYIACDVCPEKFGNMQDFNEHALAIHAGSYDPDNQNKCVDGRRTDCPICGKKNSGYPNLVKHLKIVHNEEKPHYCKHCDAKYEYATELNKHIYIEHSDKVLGKQEPDMSLVKEETEEYHYSCTECNAIFETVDAWTDHQVAEHNQIAHHCDQCEKKFLRPSELAEHKNSHLRVKFYPCSICNNSYSTPQKLSEHVQQAHPGATIVGPNGESEFFCDLCIRSFKSRQAYSNHMRIHSKVPTTNRKPGEPKGFSPQIIGKPIRHFSIVQQPGISQAPYKPNINVPNAPYSCDICGKGFMHKKNIWKHKKVLHADMVNDRNDSEENTMHASTEEDEYNPDENGAMLSTPQFNSFNFANLPNSMQSTPSKDAMPFSCDLCYKRFPLKTSLWKHKRAKHGIINASSTDPASVEASGSSRSSCTICKISFADKKSYYRHRKNVHKSTVQMCKLCGKPLNSTLELYEHLKSAHARELLGYNESQGPSKAQEVIPDVDMDYEPEQESLDPSADYQACYPCDTCGKQFVGLLALQNHQCVNQMNPQSQTFDCEICHKSYTSIAALKSHRGWHLRSPDGKAAANNSGLWMPQNKVTNKVSKYEVLDASQLARVQHSIAPTPSSSSAAVKRRLPPEVEVTVVNPNKKLRSDDSVDIDNQTNMSTGIDDRYCNICDREFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLIVHMKKHYDGGEGSSVMTQVDDEIYACEVCGERFNNSAEYNMHRESQHGEDETAGESEEDDGGSIPMPQPGEFTCAQCGDGVATPRDLIAHRTMHATPTKFYCNICNVYFARAIDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00875540; iTF_00874679;
90% Identity
iTF_00875540; iTF_00874679;
80% Identity
-